Jurnal Ilmiah Manuntung
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No full textDiabetic wounds are a form of diabetic complications that results in wounds experiencing deeper tissue damage and a longer healing process due to the condition of hyperglycemia. One of the plants known to the community as a wound medicine is the Malaysian grass plant (Chromolaena odorata L). The purpose of this study was to determine whether the ethanol extract of Malaysian grass leaves can accelerate the wound healing process in diabetes mice.The research process using the induction of alloxan monohydrate and the wound observed in this study was a cut. Diabetes mice were injured along 1.5 cm on the back of the scalpel and then divided into 5 treatment groups namely not treated (KN), ointment Betadine® (KP), ethanol extract of Malaysian grass leaves at a dose of 5 mg (P1), 10 mg ( P2) and 15 mg (P3). Basting is done twice a day for 14 days.One Way Anova analysis results 0.033> 0.05 which shows that there are significant differences between each treatment group. In the study it was found that treatment group 3 with a dose of 15 mg better accelerated wound healing and followed by positive control and treatment group 1.
 
No full textPalm trees is one plantation commodities important in development sub the plantation sector, among others to meet the needs of domestic, and as a commodity export foreign exchange producing countries. Cream sunscreen is made with an emulsion phase (VCO, lanolin, stearic acid and cetyl alcohol) and aqueous phase (triethanolamine, glycerin, aquadest). TiO2 was added with various concentrations of F0 (0%), F1 (5%), F2 (10%), and F3 (15%). The research vco oil colorless and odorless typical fresh coconut. Produce the centrifugation does not happen the separation between the oil and the water pH value the range of 6.87-7.63; viscosity and range of cp 12400-21600; SPF value at F0 (0.189); F1 (2.857); F2 (4.252); F3 (6.154). Of the value of the two of them have met the standards according to the SPF concentration F2 and F3.
 
No full textHyperuricemia is a condition of abnormal health hence increasing urid acid level within blood that is up in normal value spesificaly for man is over 7,0 mg/dL and for woman is over 6,0 mg/dL. Ekor naga leaves (Rhaphidophora pinnata L.f.) have some second metabolic compound namely flavonoid and alkaloid that have a capability to hampering xhantine oxidase enzyme. The objective of this reseach is to know the effectiveness giving ethanol extract of ekor naga leaves for decreasing urid acid level and to know the effectiveness dose ethanol extract of ekor naga leaves for decreasing uric acid level. The sample of this reseach was ethanol extract of ekor naga leaves, allopurinol as positive control, chicken liver juice and potassium oxonate as inductioun of hyperuricemia. The design of this research is complete random design with 5 action where in one action consist of 5 mice. The group of action was K+ Allopurinol 0,26mg/kgBB, P1 extract 125mg/kgBB, P2 extract 250mg/kgBB, and P3 extract 375mg/kgBB. The best dose is dose II (250mg/kgBB) with percentage of decreasing uric acid is 45,22%. Than dose III (375 mg/kgBB) with perfentage of dereasing urid acid is 44,66%, and dose I (125 mg/kgBB) with percentage of the decreasing uric acid is 39,60%. Moreover, it can be concluded that all dose of ethanol extract ekor naga leaves have an activity as antyhiperuricemia
No full textThe kepok banana peel extract (Musa paradisiaca Linn) and avocado peel extract (Persea americana Mill) contain alkaloids, flavonoids, saponins and steroids. There is a linear relationship between antioxidant activity and sunscreen capability. The stronger antioxidant activity,the better sunscreen capability will be. This study aims to determine antioxidant activity and sunscreen capability from the combination of kepok banana peel extract and avocado peel extract compared to it’s single form. This study was conducted with quota sampling. The preparation of ethanol extract from kepok banana peel and avocado peel were using maceration method with 96 % of ethanol. The study was started by collecting samples, making the extract with 96% ethanol solvent, then continue with phytochemical testing, antioxidant activity testing of kepok banana peel extract and avocado peel extract with variation ratio (1:0), (1:1), (1:2), (2:1), (0:1). Further tests including cream formulation, cream stability test and in vitro SPF value determination was also conducted. The result of IC50 determination from : kepok banana peel extract is 122,77, belongs to medium category; avocado peel extract is 11,50, belongs to very strong category; (kepok banana peel extract : avocado peel extract) (1:1) is 39,88, belongs to very strong category; (kepok banana peel extract : avocado peel extract) (1:2) : 25,31, belongs to very strong category; (kepok banana peel extract : avocado peel extract) (2:1) : 76,77, belongs to the strong category. The result of SPF measurement from the single form kepok banana is 16,21, belongs to ultra category; single form avocado peel is 21,21, belongs to ultra category; (kepok banana peel extract : avocado peel extract) (1:1) is 21,32, belongs to ultra category; (kepok banana peel extract : avocado peel extract) (1:2) is 21,52 belongs to ultra category; (kepok banana peel extract : avocado peel extract) (2:1) is 21,51, belongs to ultra category. The antioxidant activity from the variation ratio of banana peel extract and avocado peel extract (1:2) is stronger than the single form of banana peel extract, but it is weaker than the single form of avocado peel extract. The combination of kepok banana peel extract and avocado peel extract (1:2) has better sunscreen capability than it’s single form
No full textBeluntas (Pluchea indica (L.) Less) is a plant that is often used in traditional medicine because of the presence of several substances that have activity as antimicrobial compounds. Beluntas leaves contain secondary metabolite compounds such as flavonoids, alkaloids, tannins, steroids, terpenoids and saponins which can function as antibacterial. This experimental research aimed at obtaining beluntas leaf extract gel and to determine the physical stability and the effectiveness of beluntas extract gel against Propionibacterium acnes. The first step is drying the beluntas leaves and and extracted by maceration method with 70% ethanol solvent. The extract obtained was then formulated into a gel and evaluated, the evaluation results show that formula 1 is the most stable. The results showed that beluntas leaf extract gel was effective in inhibiting the growth of Propionibacterium acnes, the inhibition zone obtained was categorized as strong, where the average diameter before the accelerated stability test was 12.02 mm and 11.58 mm after the accelerated stability test
No full textJamu (Indonesian herbal medicine) are prohibited from containing chemicals medicine which are isolated or synthetic chemical compounds. Chemical compounds which is commonly added in jamu pegal linu (rheumatic pain) is phenylbutazone. One simple alternative test for detecting chemicals medicine content is to use a strip test. The purpose of this study was to determine the presence or absence of phenylbutazone content in jamu using a strip test. The research conducted is experimental research. This study used 6 samples of jamu pegal linu which were extracted using 95% ethanol solvent. The strip test is carried out by immobilizing reagents into Whatman’s filter paper using the impregnation method. Data obtained from observations of the color change of the strip test. The results showed that strip test made with alizarin red reagent and potassium hexacyanoferate (III) identified 2 samples of jamu pegal linu containing phenylbutazone, namely sample D and E, from 6 samples that circulated in Sungai Pinang District, Samarinda
No full textFoot odor is a common body odor problem. The smell of feet makes oneself and people around uncomfortable, the smell of feet can be eliminated by washing the foot using soap, using a tabun powder. However, the foot wash using soap or powder is assessed less practical. Footsanitizer Spray is a new innovation of foot odor relievers that are practical and efficient use. Stirring process will affect product quality especially particle size distribution. So in this study aims to assess the effect of speed and time stirring of physical characteristics of the preparation of the foot sanitizer spray. In this research has been done variation of speed and stirring time, variation of stirring speed is done by varying the stirring speed at 300 rpm, 500 rpm and 700 rpm. Variation in stirring time is done by varying the stirring time for 1 hour, 2 hours and 3 hours. From the results of this research can be concluded that coffee beans extract and ginger rhizome can be used as a spray footsanitizer. And the greater the speed of the mixing form of the Footsanitizer spray the more cloudy and the viscosity value and type weight is getting bigger. The longer the stirring also leads to greater viscosity and density values.
 
No full textPomegranate is one of the plants of the Lythraceae family. Pomegranate plants are spread from the subtropics to the tropics, from the lowlands to altitudes below 1000 masl. Pomegranate contains flavonoid compounds that can be used as traditional medicine for hepatoprotectors. The aim of the researcher was to determine the total flavonoid levels in pomegranate juice (Punica granatum L) by UV-Vis Spectrophotometry. The method used in the study is the Chang method. Identification of flavonoids with concentrated HCl reagents and magnesium metal causes a change in color to red which indicates a positive sample containing flavonoids. The results of the study showed total flavonoid levels contained in pomegranate juice 0.0075766% QE. Results Variation Coefficient Value (% KV) of the sample is 0.7475%, Variation Coefficient (% KV) is the percentage ratio between the standard deviation and the average. % KV is used in grading to express precision
No full textEndophytic fungi are one of the microorganisms that live in plants and symbiotic with their host plant produce secondary metabolites. This study aims to determine the optimum growth profile of endophytic fungus isolated from the leaf of Anredera cordifolia (Ten.) Steenis namely isolate I5 as antibacterial. The fungus growth profile optimization analyzed by a correlation between fermentation time and mycelium weight, which collected every 24 hours for 15 days. The media were varied at pH conditions of 4, 7, and 8 in each PDYB medium (glucose and fructose substrates). The results showed that isolate I5 grew optimally on the 13th day on the PDYB medium pH 8. Ethyl acetate extract 5% of isolate I5 could inhibit bacteria growth with the largest inhibition zone diameter against Staphylococcus aureus of 9.96 mm (± 0.60) and Escherichia coli of 9.03 mm (± 0.46)
No full textPharmacy Department A.M. Parikesit Regional General Hospital always working to improve the quality of service, analyses is need to find the performance in Pharmacy Department A.M. Parikesit Regional Public Hospital. The concept of the balanced scorecard is a performance evaluation tool that is comprehensive, coherent and relevant to be applied in hospitals for improving the performance of every aspect of total. The study to evaluate the performance Pharmacy Department A.M. Parikesit Regional General Hospital through learning and growth perspective. This research used non experimental case study arrangement research the explorative descriptive approach. Data collection was retrospective and prospectively in the form of quantitive data. Qualitative data was obtained by questionnaires, depth interview with the head of Pharmacy Departmen A.M. Parikesit. The quantitative data obtained through direct observation and personnel file. The results of research with the used balanced scorecard at a performance perspective learning and growth shown that: a. human capital: Good category productivity of employess, the level of employee productivity is 86.73%, the percentage of employees who received training in 2013, 2014 and from January to July 2015 is respectively for 15.38%, 32.25% and 97, 72%, the average value of the high category in morale, job satisfaction, knowledge, empskill and talent; b. information capital showed the average category of high on the aspect of information technology, a database and network, but need the information management system updates for support the management and drug reporting and need to improve communication with the customer network.; c. organization capital showed the value of the average category of high on the aspect of cultural organization ,leadership and alignment