Jurnal Ilmiah Manuntung
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UJI EFEK ANALGESIK EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) PADA MENCIT PUTIH JANTAN (Mus musculus) DENGAN INDUKSI NYERI ASAM ASETAT
Get PDFKersen leaf (Muntingia calabura L.) contains tannins, flavonoids and polyphenol compounds allegedly have analgesic effect. The objective was to determine the analgesic effect of ethanol extract of kersen leaves and to determine the most effective analgesic dose. This study was an experimental research. Leaves were extracted with ethanol 70% and the analgesic effect test was divided into 5 groups: negative control treatment (distilled water), positive control (mefenamic acid 2.6mg/kg), kersen leaf ethanol extract first dose (100mg/kg), second dose (200mg/kg) and tthird dose (400mg/kg). Giving treatments by oral, after 30 minutes, the mices were given a pain inductor with 0.5% acetic acid by intra peritonial administration. Analgesic power was calculated by counting the number of writhing in mice for 1 hour. The results showed that the ethanol extract of cherry leaf has analgesic effect. From the calculation of the first dose analgesic power (42.9%), second dose (59.4%) and the third dose 69.9%. Statistical test results kruskal wallis value of p=0.011 (p<0.05) showed a significant difference between all analgesic treatment groups. The conclusion of this study is all of the ethanol extract had analgesic effects on male white mice, whereas a dose of 400mg/kg is the most effective analgesic dose
PERSEPSI MASYARAKAT TERHADAP DAMPAK KESEHATAN DARI AKTIVITAS PENAMBANGAN BATUBARA DI KAMPUNG TASUK KABUPATEN BERAU
Get PDFMining is an ancient occupation, long recognized as being arduous and liable to injury and disease. Coal mining carried dangers from exposure to noise, heat, and airborne dusts, causing many associated diseases. Respiratory diseases caused by coal mine dust are pneumoconiosis, chronic bronchitis, and emphysema. The process of coal mining involves the discharge of huge amount of effluent into the surface water. Effluent from coal mine contains high load of TSS, TDS, calcium carbonate and heavy metals accumulates in water, soil, sediment and living organism. Coal mining has long been established in East Kalimantan. This paper explores the public perceptions of the health and environmental impact of opencast coal mining in Kampung Tasuk, Gunung Tabur, Regency of Berau, East Kalimantan. The obtained result may be used as an input to formulate and redesign the community development program of coal mining company in Berau. The public perception of coal mining activity in kampung Tasuk was dissastified with costumer satisfaction index 58.
FORMULASI PATCH KOSMETIK LENDIR BEKICOT (Achatina fulica) DENGAN POLIMER KITOSAN DAN BERBAGAI VARIASI AMILUM
Get PDFThe research on cosmetic patch formulation containing snail slime with a variety starch was aimed to determine the type of starch that could produce a patch preparation with a good physical characteristic had been conducted. Cosmetic patch formulation of snail slime was using combination of chitosan and starch polymers such as corn, potato and tapioca starch. The method was used the solvent evaporation technique. The evaluation of patches include weight uniformity, folding endurance, thickness, moisture content, moisture uptake and stability of the patch. The combination of chitosan and starch polymers produced patches that had pH 5 with color uniformity, smoothness of surface and easily removed from the mold. The results showed that patches containing tapioca starch gave weight uniformity that did not much different on each replication that was 0,568 ± 0,03. Patches containing corn starch provided thickness values on each replication did not much different from 0,16± 0,01. Patches containing potato and tapioca starch produced patches that was accordance with the standard parameter of folding endurance was more than 200 times. Patches containing corn and tapioca starch producing patches accordance with the standard parameter of moisture content were less than 10 %. Patches containing potato starch gave patch a high moisture uptake that was 8,2%. The combination of chitosan and tapioca strach as polymers produced patch preparation with a good characteristic on the formulation of snail slime cosmetic patch
PEMANFAATAN EKSTRAK HERBAL TERHADAP PRODUKTIVITAS DAN MUTU AYAM PEDAGING SEBAGAI UPAYA KETAHANAN PANGAN DI KALIMANTAN TIMUR BERBASIS PETERNAKAN RAMAH LINGKUNGAN
Get PDFQuality broilers become a serious problem for farmers. Many studies done to solve these problems, one of them by making use of natural materials. Some plants are known to have the ability to improve the quality of broilers as bitter, ginger and onions tiwai. This study aimed to determine the effect of ethanol extract of the herb on the quality of broilers. Subjects used is Strain Cobb broiler DOC. A total of 60 chickens were kept in a cage stage measuring 1.5 x 1.5 m for 30 days. Subjects were divided into five treatment where each treatment consisted of four tails. The experiment was conducted with three replications using a completely randomized design. Such treatment includes control (P0), the ethanol extract of sambiloto 0.02 % (P1), the ethanol extract of umbi bawang dayak 0.05 % (P2), the ethanol extract of temulawak 0,075 (P3), Product Imugas (P4). Quality parameters include coarse fat content and crude protein. The data obtained were statistically analyzed using analysis of variance (ANOVA). The results showed that the treatment of all types of ethanol extract of the herb can improve the quality of broilers compared to control (sig < 0.05), the type of treatment is best to P4. Quality parameters which include : crude protein and crude lipid. Levels of the protein, which is the highest in treatment P4 by 23.87% . Fat content, which is the lowest in treatment P4 of 10.50
UJI AKTIVITAS EKSTRAK ETANOL GAMBIR (Uncaria gambir Roxb.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA KULIT PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus)
Get PDFGambir (Uncaria gambir Roxb.) contains flavonoids, tannins, saponins and alkaloids that can help in the healing process of burns on the back skin of mice. Gambir has been used for the treatment because it has the effect of antimicrobial and anti-inflammatory. Gambir is used by the people as a traditional medicine to treat burns.This research is experimental research. The object studied is the potential of gambir extract on healing burns of mice back skin. The number of mice used are 15 which divided into 5 groups: the positive control group (branded ointment), negative control group (vaseline flavum), group of gambir ethanol extract and vaseline flavum concentration of 25%, 35%, and 45%. Each group consisted of 3 mice.Backs of the mice induced using a heated solder which tip contained stainlees plate measuring 1x1 cm and placed for 2 seconds on the back skin of mice. The percentage of burns healing is obtained by calculating the surface area of the wound. The data were analyzed using ANOVA analysis followed by LSD test. The results showed that ethanol extract of gambir concentration of 25% with the healing burns percentage of (72.00%), the concentration of 35% (85.00%), and the concentration of 45% (88.67%) have activity on healing burns of back skin of mice. The results of data analysis using ANOVA showed that the data has significant differences with a significance value <0.05 is 0.000. LSD test results stated that each treatment group have significant differences with a significance value <0.05. It can be seen that with increasing dose will be followed by duration of burns healin
IDENTIFIKASI DAN PENETAPAN KADAR RHODAMIN B DALAM KERUPUK BERWARNA MERAH YANG BEREDAR DI PASAR ANTASARI KOTA BANJARMASIN
Get PDFCrackers are made from tapioca flour batter mixed with flavorings and colorings, still many outstanding crackers that contain ingredients banned dye Rhodamine B. Rhodamine B is a chemical used for red dye in the textile industry and plastic. Rhodamine B can cause cancer, poisoning, lung irritation, sore eyes, and sore throat. This study aims to identify and determination the levels of Rhodamine B in circulating red crackers Antasari market Banjarmasin.The population is that sold in the red crackers that sold in Antasari market Banjarmasin.. The sampling is technique incidental sampling , that is based on chance, so any population by chance met with researchers can be used as a sample. Identification of Rhodamine B was done by Thin Layer Chromatography (TLC) by using the stationary phase silica GF 254 and mobile phase is elution solvent is n-butanol, ethyl acetate, ammonia (10:4:5). Then detected with a UV lamp 254 nm and 366 nm. While for the determination of levels using Vis spectrophotometry at a wavelength of 544 nm.The results showed that the samples of 6 found one sample containing Rhodamine B, namely samples 5 (cassava crackers matches) and obtained values of 7,25 ± 3,8640 levels mg / kg. Based on these results, Rhodamine B still found in crackers that sold in the market Antasari Banjarmasin
UJI KUALITAS SERUM SIMPANAN TERHADAP KADAR KOLESTEROL DALAM DARAH DI POLTEKKES KEMENKES KALTIM
Get PDFClinical Chemistry Examination Guidelines stated several factors may affecting the stability of the specimen i.e. contaminant germs and chemicals, exposure to sunlight, the effects of temperature and metabolism of living cells such as blood cells. Blood specimens should be stored in the form of serum in a refrigerator at a temperature of 2-80 C. This study aimed to compare cholesterol levels of serum with no erythrocyte and with erythrocytes during storage for 3 and 9 days at 2-8ºC. This is an analytical survey to compare cholesterol levels in serum blood during storage. Data was analyzed using Independent Sample t-test. The result showed value p (0.410) is greater than α (0.05), so there is no correlation between serum with erythrocytes and with no erythrocytes in cholesterol at a temperature of 2-8 0C stored for 3 days and the p-value (0.162) is greater than α (0.05) then pat concluded that there was no influence of serum with erythrocytes and without erythrocytes to changes in cholesterol at a temperature of 2-8 0C during storage of 9 day
KELENGKAPAN INFORMASI MENGENAI CARA PENGGUNAAN PEAK FLOW METER YANG DIBERIKAN KEPADA PASIEN ASMA DI APOTEK
Get PDFMeasurement of lung fungction is a way to determine the effectiveness of a given therapy. A monitoring asthma symptoms is to see the value of peak expiratory flow (PEF) with a peak flow meter. The measurement is objective and can be used to predict the prognosis of asthma through the monitoring of conditions of the lung. This study aims to find out information on the use of a peak flow meter explanations given to the patient’s pharmacist in a pharmacy in a town in East Java. This research method is a non-experimental with cross sectional study. This study uses observation techniques in the form of a checklist, using the concept of a mysterious patient. Sampling by the proportional method, and then the data will be processed descriptively. The research sample of 80 pharmaceutical personnel consisting of 33 pharmacists and 47 non-pharmacists. In the group of non-pharmacists and pharmacists, the points most overlooked is the explanation of the recording of the results (number 6) and compared with the best value (number 8). Pharmacists still need to improve in understanding the basics and techniques in order to use a peak flow meter can help asthma patients to monitor their asthma medicatio
FORMULASI SEDIAAN SABUN MANDI PADAT DARI EKSTRAK BUAH APEL (Malus domesticus) SEBAGAI SABUN KECANTIKAN KULIT
Get PDFAs the development time of usage and utilization of traditional medicine in Indonesia is experiencing a very rapid progress. Interest of the community to utilize natural materials back to health is greatly improved. Apple or (pyrusmalus) is one among the faforit fruit in the family rosaceae or rose-mawaran. Apple plants allegedly came from around israel-Palestine, then spread throughout the world, including indonesia. Europe and Australia is the country’s most used to develop crop of apples in agribusiness. Apples contain a natural anti oxidant which is great for the health of the skin and eyes. This research uses research methods laboratory ekperimental Soap to be created with a penembahan extract of apples made with olive oil. Apple fruit is extracted by means of maceration using penyari ethanol. Ethanol extract of Apple made in the form of solid bath soaps and bath soaps performed the examination test includes solid Favorites, pH, testing methods and solid bath Soap Irritation Test made with a concentration of 2.5%, 3.5%, 4.5%. The results of the test checks gladness solid bath Soap preparations obtained are really like 13 people, like 4 people, 3 people and less like don’t like 0, pH 8.3-7.3, on the test of irritation in the preparations of solid bath SOAP from Apple fruit extracts do not cause skin redness and itching. The conclusion of the researchers extract of apples (Malusdomsticus) can be formulated in the form of preparation of solid bath Soap. The advice of researchers is expected for the next researcher to be able to formulate the Apple fruit extract (Malusdomesticus) in the form of other preparations, such as face masks
STABILITAS DAN AKTIVITAS GEL EKSTRAK BULBUS BAWANG TIWAI (Eleutherine americana (Mill.) Urb.) SEBAGAI ANTI ACNE
Get PDFawang Tiwai has an antibacterial activity toward some microorganisms e.g. Staphylococcus epidermidis dan Propionibacterium acne, two acne related bacteria. Bawang Tiwai extract 1% and 2% were formulated into gel (no oil content, because oil could make the acne worse) with carbomer 940 as gelling agent. Physical stability of bawang tiwai gel was evaluated included stability, organoleptic, pH, homogeneity, viscosity, consistency, spreading test, and activity toward Staphylococcus epidermidis. The result showed that all formulas are stable after 7 days. The test results of antibacterial activity gel are 17,24 mm dan gel 19,75 mm to gel 1% dan 2% respectively