Jurnal Ilmiah Manuntung
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No full textThis experiment centred in metered dose inhaler (MDI) device which used routinely by asthma patient as controller therapy. MDI used ask patient’s skill more when using their medication. MDI technique informnation provided by pharmachist are important to achive optimal medication in asthma therapy. By a non experimental study, mysterious patient collect MDI technique gived by pharmacist in Tuban pharmacy using observacional and cross sectional method. Information about MDI technique comprehensive collected by two ratter as mysterious patient which assessed with checklist that got measseured by kappa to know ratter aggrement percentage. The result showed from a total sampling under 41 pharmachist which represent each 41 pharmacy in Tuban, by purposive sampling Pharmacists as pharmaceutical personnel responsible for information services at pharmacies, including information on how to use MDI. Most of the apothecary's ability level in providing information is still lacking, then continued with adequate technique, and optimal technique in providing complete information of MDI use for asthma patient. Pharmacists know how to use MDI and no pharmacist is unexpected or not familiar with MDI as an asthma therapy. Pharmacists in Tuban district have a tendency to inform only four stages of the nine stages of MDI use from Osman et al (2012), ie at the 1st, 3rd, 5th, and 6th stages of MDI us
PENGARUH KEMASAN TERHADAP AKTIVITAS ANTI BAKTERI SUSPENSI ERITROMISIN SETELAH PENYINARAN DENGAN SINAR MATAHARI LANGSUNG
Get PDFErythromycin is a type of antibiotic medication. The drug is unstable when in the water because it can undergo hydrolysis process. Fortunately, it can be prevented by making dry syrup dosage form. In addition to hydrolysis, erythromycin can also have photolysis. For preventing the reaction, it can be done by packing the medication in an opaque and tightly closed container. This research was conducted to determine the effect of packaging on the stability of erythromycin suspension that has been exposed to direct sunlight within a period. The research was done by exposing erythromycin suspension, which was packed with three kinds of color packaging namely brown, translucent, and opaque, for 30 minutes, 60 minutes, 90 minutes and 120 minutes, then continued by a microbiological test with a diffusion method to determine the activity of erythromycin against Staphylococcus Aureus. The results of the research showed the existence of diameter of barrier areas around the spots that were given a test solution. It means that the test solution has antibiotic activity against bacteria. Preparations packaged in brown color have higher inhibition when compared with the opaque and translucent. It shows that the erythromycin suspension packaged in brown colors was more efficient in stabilizing the preparatio
ANALISIS KUALITATIF FORMALIN PADA TAHU MENTAH YANG DIJUAL DI PASAR KALINDO, TELUK TIRAM DAN TELAWANG BANJARMASIN
Get PDFTofu is one of favourite food in Indonesia because it is containing the nutrients which body needs, such as protein. Tofu comes from processed soybeans and contains high water, so it can only save for 1 or 2 days in storage. Because of that reason several manufacturers or dealers add additional ingredients, one of them was formaldehyde to made tofu were durable to be restored and increases consumer appeal. The aim of the study was to identifity the contain of formaldehyde at crude tofu in Kalindo, Teluk Tiram and Telawang market Banjarmasin. The investigated sample was white crude tofu were 19 samples obtained with accidental sampling. The type of research was descriptive research. Qualitative analysis of formaldehyde at crude tofu was done with conventional method by using Ag(NH3)2NO3 and KMnO4 0,1N reagents. The result of study shows that crude tofu was sold in Kalindo market 90% (9 of 10 samples) positive contain formaldehyde, 100% (4 of 4 samples) at Teluk Tiram market positive contain formaldehyde and 80% (4 of 5 samples) at Telawang market positive contain formaldehyd
PENETAPAN KADAR ASAM LEMAK BEBAS DAN BILANGAN PEROKSIDA PADA MINYAK GORENG YANG DIGUNAKAN PEDAGANG GORENGAN DI JL. A.W SJAHRANIE SAMARINDA
Get PDFFree fatty acids and peroxide are part of cooking oil quality parameters. This study aims to determine the levels of free fatty acids and peroxide value in cooking oil used by fried merchant in Jl. A.W. Sjahranie Samarinda. Sampling was done by total sampling which is cooking oil before frying and after frying a few times from four fried merchants. Determination of free fatty acid content using alkalimetry method and levels of peroxide using iodometric method.The test results of the free fatty acid content of samples A, B, C, D cooking oil before frying is equal to 0.16%; 0.27%; 0.33%; 0.32%, and free fatty acid levels after few times frying is 0.19%; 0.29%; 0.37%; 0.36%. The test results of the peroxide sample A, B, C, D cooking oil before frying in the amount of 18.95 meq O2/kg; 27.63 meqO2/kg; 24.67 meq O2/kg; 23.29 meq O2/kg. Peroxide levels after several times frying is 26.25 meqO2/kg; 35.72 meqO2/kg; 34.54 meqO2/kg; 33.16 meqO2/kg. Average levels of free fatty acids cooking oil before frying is 0.27% and after frying to 0.30%, or an increase of 12.04%. While the average level of peroxide cooking oil before frying of 23.64 meqO2/kg and after frying be 32.42 meqO2/kg or an increase of 37.16%
No full textMicrobial on food are caused by various factors such as nutrients, water, and temperature. If total amount of microbes increase it would damage food and if it ingested could affect grastrointestinal track. Snack, especially unregistered snack such as syrup in school is one of important problem to concerned. The purpose of this study is to detect the present of Staphylococcus aureus and Salmonella in syrup in four elementary schools in Cimahi. Detection of Staphylococcus aureus is done using BPA medium, while detection of Salmonella is using Indol test, methyl red test, Voges Proskauer test, Citrate test and Gram staining. The result shows that the syrup from the elementary school contains Staphylococcus aureus but not all of samples of syrup give positive result of Salmonella. Based on the requirements which in set in SNI that microbes in syrup should not be contain to Staphylococcus aureus is negative/ml and Salmonella is negative/25 ml, then syrup that sold in all four elementary schooldi not qualified
No full textABSTRACT
This study aims to determine the effect of using gelling agent and chemical penetration enhancer on the solid dispersion Ibuprofen gel in increasing the transdermal drug penetration. Inhibition of the COX-1 enzyme caused by ibuprofen in oral administration can cause side effects of gastrointestinal disorders, dyspepsia, diarrhea, upper gastrointestinal infections, nausea and bloating, resulting in a topical route to reduce side effects. The gel is prepared using hydroxy propyl methyl cellulose (HPMC) and carbopol® as gelling agents, and also propylene glycol and glycerin as chemical penetration enhancer compounds. The gel evaluation are viscosity, pH, spreadability and penetration flux rate. The value of the formula 3 penetration flux is 1.5383 ± 0.029 ug / cm2.minute, the formula 1 is 1.403 ± 0.055 ug / cm2. minute, the formula 2 is 0.756 ± 0.071 ug / cm2 minute, while the formula 4 is 0.5404 ± 0.106 ug / Cm2. minute. The amount of gelling agent concentration and chemical penetration enhancer compound effect on the value of the flux penetratio
No full textExposure of the skin to ultraviolet (UV) radiation from the sun has various adverse effects, photoaging and skin cancer are of great concern. The ability of botanical antioxidants for prevention of photocarcinogenesis and photoaging had been widely known. Bawang tiwai (Eleutherine bubosa) is traditionally used by the native people of Kalimantan for cancer treatment. The ethanolic extract of bawang tiwai originated from Banjarbaru district, South Kalimantan had strong antioxidant activity. The objective of the study was to formulate Eleutherine bulbosa extract into cream and evaluate its scavenging activity. Antioxidant activity of Eleutherine bulbosa cream was assessed by 2-diphenyl-1-picrylhydrazyl (DPPH) method. The Eleutherine bulbosa extract was incorporated into five cream formulas in varied concentration of emulsifying wax and cetyl alcohol. Evaluation of cream including physical appearance, pH, viscosity, stability, and microbial growth test. The result showed that Eleutherine bulbosa cream has antioxidant activity and good physicochemical qualit
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN FUNGSI PARU PADA PEKERJA PEMBUAT KASUR (STUDI KASUS DI DESA BANJARKERTA KARANGANYAR PURBALINGGA)
Get PDFMattress maker is one of the high-risk job of lung function. Dust from the production of an effect on lung function. Research describe dust from production assosiated to the pulmonary dysfunction. Previous studies explain the illness rate reached 70% in workers who inhale cotton dust. Describe the various factors assosiated to the pulmonary dysfunction between age, nutritional status, years of service, the use of masks, ventilation, workplace ownership, and the amount of dust inhaled by the incidence of lung function, job characteristics, and the amount of dust inhaled by the mattress makers in the District Karanganyar Purbalingga. This study was an cross-sectional, with a total sample of 80 workers mattress maker. The independent variable in this study is a age, nutritional status, years of service, the use of masks, ventilation, workplace ownership, and levels of total particles inhaled. The analysis was performed using univariate, bivariate and multivariate as well as by calculating the ratio of prevalence. The results showed that there are 4 variables significantly associated with lung function. that workers exposed to dust> 0.2 mg/m3 per day with a ratio of 27.203 prevalent (95% CI = 1.885 to 39,257) Working period (≥ 10 years), with a ratio of 21,502 prevalent (95% CI = 9.559 to 483,65) The use of masks (not always use) with the ratio of 43.965 prevalent (95% CI = 2.831 to 682,80) Ownership separate workplaces with 27.583 prevalent ratio (95% CI = 1.955 to 389,25). The risk factors significantly associated with impaired lung function is inhaled dust particles, years of service, the use of masks and a separate work between sections. suggested to the labor department and the health department to conduct promotive and preventive so that workers can be maintained mattress maker of health and safety wor
UJI AKTIVITAS EKSTRAK ETANOL 96% BIJI SRIKAYA (Annona squamosa L.) SEBAGAI ANTIDIARE YANG DISEBABKAN OLEH BAKTERI Shigella dysenteriae DENGAN METODE DIFUSI CAKRAM
Get PDFThis research aims to find out how to extract ethanol 96% seed custard apples as Antidiarrhoeal that is caused by bacteria Shigella dysenteriae with different concentrations and compare with chloramphenicol. In addition, also to find out whether their respective inhibitory power of concentration of ethanol 96% seed extract custard apples have a difference in meaning. Research done by experimental methods, was carried out in the laboratory of pharmaceutical Academy IKIFA. Testing was done using the diffusion disc method. The concentration of ethanol 96% seed extract custard apples are used i.e. 15%, 30%, 45%, 60%, and 75%. As positive controls used chloramphenicol 30 µg/ml and NaCl 0.9% as the negative control. Each test is carried out as many as eight repetitions. The results showed an average diameter drag power which formed on the test solution with a concentration of 15%, 30%, 45%, 60% and 75% respectively of 6,887 mm, 11,49 mm, 8,144 mm, 7,694 mm, 7,150 mm, whereas for chloramphenicol for 40,31 mm. Based on the results of the statistical tests there are meaningful differences between concentrations showed a meaningful difference between the concentration of 15% and 30%, 15% and 60% and 15% and 75%. Conclusion of this research is at a concentration of 15%, 96% ethanol extract of seeds of custard apples have been able to inhibit the growth of bacteria, Shigella dysenteria
No full textImmunization is a process to make the body's immune defense system against invading microorganisms (bacteria and viruses) that can cause infections before these microorganisms have a chance to invade our bodies. Hepatitis B immunization is the immunization to prevent the body less susceptible to hepatitis B virus. The purpose of this study was to identify whether there is the Relationship Between Hepatitis B Immunization Status Completed At Age 0-6 Month With Events Hepatitis B in the Work Area Puskesmas Perawatan Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu.This research method is analytical survey and cross sectional approach for studying the dynamics of the correlation between risk factors and the effects of the approach, observation or data collection at once at a time (point time approach), the sampling technique is taken with total sampling technique that met the inclusion criteria and exclusion of mothers with babies were recorded in the register Puskesmas Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu. The data obtained were analyzed using chi-square test with significance of 0.05. Chi-Square test results obtained there is a significant relationship between the completeness status of hepatitis B immunization (P = 0.005) with the occurrence of Hepatitis B, for the conclusion in this study found no relationship between the completeness status of hepatitis B immunization with Hepatitis B in Puskesmas Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu. It is hoped that no more infants are immunized against the completeness of incomplete hepatitis B immunization to reduce the incidence of hepatitis and reduce infant mortalit