Pustaka Kesehatan
Not a member yet
642 research outputs found
Sort by
Hubungan Antara Karakteristik Individu dan Manual Material Handling dengan Keluhan Muskuloskeletal Akibat Kerja (The Relationship Between Individual Characteristics and Manual Material Handling With Musculosceletal Complaints Due To Work)
Get PDFOccupational Health and Safety (K3) is one of the requirements to improve employeeproductivity, beside that the Occupational Health and Safety is every labor rights.Conveyances Workers in Tanjung Market Jember generally works using their body as a toolto carry goods, and done in a long time and repeatedly. It is potential to experience workrelatedmusculoskeletal complaints. The aim of this study was to analyze the relationshipbetween individual characteristics and Manual Material Handling with musculoskeletalcomplaints due to work. The method used was cross sectional with the respondents of 60people, using lambda association test analysis techniques. The results of data analysisshowed no relationship between age (Ï = 0.0001), and nutritional status (BMI) (Ï = 0.041),with musculoskeletal complaints due to work. While the smoking habit (Ï = 0.249) andworking period (Ï = 0.170) showed no relationship with musculoskeletal complaints due towork, and for manual material handling (MMH) (Ï = 0.018) by using the method of RWL andLI measurement indicated there was a relationship between manual material handling withmusculoskeletal complaints due to work. Based on these results the government isexpected to take action to prevent the occurrence of occupational diseases, especially inthe informal sector.Keywords: Individual Characteristics, Manual Material Handling, MusculoskeletalComplaints, Conveyances Workers
Perbedaan Kualitas Hidup Lansia yang Tinggal di Komunitas dengan di Pelayanan Sosial Lanjut Usia (The Different of Quality of Life Among the Elderly who Living at Community and Social Services)
Get PDFQuality of life is a very board concept that was affected by individual physical condition, psychological, level of independence, and individual's relationship with the environment. This research aimed to determine differences in the quality of life of the elderly who living at community and Social Services, according to the physical, psychological, social, and environmental domain. This research was analytically studies using cross sectional design. The number of sample was 210 respondent. Mann Whitney and Kruskal Wallis test (alpha 0,05) was applied to analyze the data. There were not significant difference between quality of life of the elderly living at community and at Social Services in Jember (p=1.000). Based on domain quality of life, the were significant difference between physical, psychological, social, and environmental domain of the elderly living at community and Social Services in Jember. Â Keywords: elderly people, quality of life, community, Social Services Â
Studi Kualitas Pelayanan Apotek Ditinjau dari Tingkat Kepuasan Konsumen di Kecamatan Sumbersari Jember (Study of Pharmacy Quality Service According to Costumer Satisfaction Levels in Sumbersari Jember)
Get PDFPharmacy is one of many place that provide products and services linked to customer satisfaction. To increase the quality of pharmacy services, we need know costumer satisfaction levels about the pharmacy services they received currently. The aim of this research was to know customer satisfaction level of pharmacy services. This was the descriptive type research with purposive sampling. The sampling method was proportional stratified random sampling. Samples were 100 respondents from 13 pharmacies. Data obtained by distributing questioner that measure the level of satisfaction based on five dimensions of satisfaction that is tangible, responsiveness, reliability, assurance and empathy. The data then was analyzed using correlation value, by comparing the perception of reality and hope which was showed in Cartesian diagram. The results showed that consumers have a good perception of the pharmacy service on all the dimensions indicated on the interpretation of high-value, which means the level of satisfaction is very satisfied. Keywords: satisfaction, pharmacy services, Jembe
Sintesis asam 2-(2-(4-kloro-N-(2,6-Diklorofenil)benzamida) fenil)asetat sebagai salah satu turunan diklofenak yang merupakan kandidat obat penghambat COX (siklooksigenase) (Synthesis 2-(2-(4-Chloro-N-(2,6-dichlorophenil)benzamido)phenil)acetic acid as dic
Get PDFSodium diclofenac is an analgetic agent as an antimetabolite that used for treating pain. Several compound as a derivative diclofenac has been synthesis for increase its activity and reduce side effect. 2-(2-(4-Chloro-N-(2,6-dichlorophenyl) benzamido)phenyl)acetic acid is a derivate of Sodium diclofenac that synthesized for development new drugs. Synthesis 2-(2-(4-Chloro-N-(2,6-dichlorophenyl) benzamido)phenyl)acetic has benzoylation reaction between Sodium diclofenac and 4-Chlorobenzoil Chloride to give the target compound (2-(2-(4-Chloro-N-(2,6-dichlorophenyl) benzamido)phenyl)acetic acid).This compound has been purified by Column Chromatography and give yellow color with melting point 143-145oC and then fix identification by H-NMR 400 MHz and KBr FTIR. 2-(2-(4-Chloro-N-(2,6-dichlorophenyl) benzamido)phenyl)acetic acid can synthesized and resulted 8.39 % of yield. Â Keywords: Sodium diclofenac, 2-(2-(4-Chloro-N-(2,6-dichlorophenyl)benzamido)phenyl)acetic acid, pain
Perubahan Morfologi Staphylococcus aureus Akibat Paparan Ekstrak Etanol Biji Kakao (Theobroma cacao) secara In Vitro
Get PDFStaphylococcus aureus (S. aureus) adalah bakteri Gram positif yang sering menginfeksi manusia. S. aureus resisten terhadap banyak antibiotik misalnya kloramfenikol, ampisilin, eritromisin, penisilin, dll. Ekstrak etanol biji kakao memiliki daya hambat terhadap pertumbuhan S. aureus secara in vitro, namun belum dapat ditunjukkan perubahan morfologi yang terjadi pada S. aureus setelah diberikan ekstrak etanol biji kakao. Tujuan dari penelitian ini adalah untuk mengkaji perubahan morfologi S. aureus setelah diberikan ekstrak etanol biji kakao. Jenis penelitian yang digunakan adalah Quasi Experimental dengan rancangan Posttest OnlyControl Group Design. Sampel yang digunakan adalah S. aureus dengan bahan uji yaitu ekstrak etanol biji kakao konsentrasi 31,2 mg/ml; 15,6 mg/ml; dan 7,8 mg/ml sedangkan kontrol negatifnya adalah aquades steril dan kontrol positifnya adalah suspensi sefaleksin 4 µg/ml. Metode yang digunakan untuk pengamatan perubahan morfologi S. aureus adalah uji scanning electron microscope. Hasil penelitian dapat disimpulkan bahwa ekstrak etanol biji kakao pada konsentrasi 15,6 mg/ml dan 7,8 mg/ml menyebabkan terjadinya perubahan morfologi S. aureus berupa pembesaran ukuran diameter sel dan tidak terpisahnya septum. Pada konsentrasi 31,25 mg/ml juga tampak adanya penonjolan pada dinding sel bakteri. Kata Kunci: Antimikroba, Kakao, SEM, Staphylococcus aureu
Pengaruh Posisi Kerja terhadap Kejadian Low Back Pain pada Pekerja di Kampung Sepatu Kelurahan Miji-Prajurit Kulon-Mojokerto
Get PDFLow Back Pain merupakan gejala utama yang dilaporkan kepada praktisi kesehatan berkaitan dengan menurunnya produktivitas kerja. Posisi kerja yang ergonomi menjadi faktor penentu terjadinya Low Back Pain. Penelitian ini bertujuan mengetahui adanya pengaruh posisi kerja terhadap kejadian Low Back Pain. Sebanyak 60 responden dibagi menjadi 2 kelompok kerja: berdiri dan duduk. Indeks nyeri diukur dengan Visual Analog Scale (VAS) diikuti dengan Pain Assessment Scale. Data dianalisis dengan Chi Square Test dan didapatkan nilai 0,037. Nilai X2 hitung pada posisi kerja duduk lebih tinggi yaitu 14,267Â dibandingkan dengan posisi kerja berdiri yaitu 13,467. Kedua posisi kerja baik berdiri maupun duduk sama-sama mempunyai pengaruh yang signifikan terhadap kejadian Low Back Pain. Namun posisi kerja duduk lebih tinggi pengaruhnya dibanding dengan posisi kerja berdiri. Berdasarkan data hasil penelitian menunjukkan bahwa posisi kerja memang memiliki pengaruh terhadap kejadian Low Back Pain. Kata kunci: posisi kerja, low back pain, kampung sepatu, ergonom
Efek Antiangiogenik Ekstrak Etanol Buah Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) pada Membran Korio Alantois (CAM) Embrio Ayam
Get PDFAngiogenesis is the growth of new blood vessels that are used to supply nutrients and oxygen including cancer cells. Phaleria macrocarpa contains tannin, saponin, alkaloid, and flavonoid, known as an antiangiogenesis. This study determined the antiangiogenic effects of ethanolic extract of Phaleria macrocarpa on chorio allantoic membrane of chicken embryos. The antiangiogenesis trials used chorio allantoic membrane of 9 days chicken embryos. There were 5 groups, negative control group [K(-)] and 4 treatment groups (P), each group containing 4 eggs. K(-) group using aquadest and tween 80%; P groups with ethanolic extract of Phaleria macrocarpa at a concentration 10 ug/µL, 40 ug/µL, 80 ug/µL, 160 ug/µL for P1, P2, P3, dan P4 respectively. The number of new blood vessels on chorio allantoic membrane were K(-): (42.5 ± 14.57), P1: (28.25 ± 3.59), P2: (28.5 ± 1.73), P3: (15 ± 4.32), and P4: (6.5 ± 1.73). In conclusion, the ethanolic extract of phaleria macrocarpa has an antiangiogenic effect on chorio allantoic membran by decreasing the number of new blood vessels.Keywords: angiogenesis, Phaleria macrocarpa, ethanolic extract, chorio allantoic membran
Respon Limfosit T Sitotoksik Pada Gingivitis Setelah Pemberian Kurkumin (Citotoxic T Lymphocytes Response in Gingivitis After Curcumin Given)
Get PDFGingivitis is a form of periodontal disease most common in the community. Gingivitis is caused by bacteria in subgingival plaque, one of them is Porphyromonas gingivalis. Curcumin is a phenolic yellow pigment obtained from the powdered rhizome of Curcuma sp. which has anti-inflammatory effects. Curcumin can reduce the number and responses of cytotoxic T lymphocyte by signing on IL-1, IL-2, IL-12, and TNF. Variables observed in this study is the number and response of cytotoxic T lymphocyte in male Wistar rats gingiva. 16 male Wistar rats were divided into two groups: control and treatment groups. To cause gingivitis rats were injected with bacteria P. gingivalis 3x108 CFU concentrations as much as 0.02 ml of the gingival sulcus maxillary left for 2 days. The control group was given PBS and treatment group was given curcumin dose of 0.03 mg / g BW in intragastric starting from day 2 after induction of P. gingivalis. Rats sacrificed on day 3 (72 hours after the induction of P. gingivalis) and day 5, followed by extraction, fixation, tissue processing to be preparations with HE staining and IHC. Observation of the results carried out using a light microscope. Results showed that there was no cytotoxic T lymphocytes in the control and treatment groups, but in HE staining found existence of lymphocytes guess is that memory T lymphocytes (CD45). The conclusion of this study is in IHC staining method there is no difference in the number of cytotoxic T lymphocytes in the control group and the treatment, but in HE staining found existence of lymphocytes guess is that memory T lymphocytes, and the clinical features are redness and swelling until day 3 which the gingival more redness in the control group compared to the treatment group and healing has occurred on day 4 to day 5 in the control and treatment groups. Keywords: Citotoxic T lymphocytes, Curcumin, Gingivitis, Immunohistochemic
Respon Imunogenitas Antibodi Poliklonal IgY terhadap Protein Adhesi Pili 95 kDa Shigella dysenteriae
Get PDFShigella dysenteriae is the most frequently cause of deaths of dysentery cases in infants and toddlers. Shigella dysenteriae has a pili that act as an adhesin molecule and will detect in human body as antigens which is involved in producing antibodies. This study was conducted to prove that Shigella dysenteriae pili adhesion protein 95 kDa is immunogenic. This was an experimental laboratory study with quasy experimental design in vitro. The study began with mice erythrocyte cell isolation, IgY polyclonal antibodies isolation, mice intestinal enterocytes cell isolation, hemagglutination inhibition test, and adhesion inhibition test. The haemagglutination inhibition test showed that the pili adhesion protein 95 kDa of S. dysenteriae able to inhibit the haemagglutination of erythrocytes mice Balb/C up to ½ dilution. While, the adhesion inhibition test revealed that the fewer of antibody concentration on enterocytes, the greater bacteria attached. According to the linear regression test results, the index adhesion value increased along with the decreased of antibody concentration. In conclusion, pili adhesion protein 95 kDa from S. dysenteriae was immunogenic and could inhibit the hemagglutination and adhesion between S. dysenteriae and mice enterocytes cells.  Keywords: immunogenicity, IgY polyclonal antibody, Shigella dysenteriae, pili adhesion protein
Efek Perendaman Bahan Fissure Sealant Semen Ionomer Kaca Pada Minuman Berkarbonasi Terhadap Pelepasan Fluor (The Effects of Immersion Material Glass Ionomer Cement Fissure Sealant on Carbonated Drinks to The Release of Fluoride Ions)
Get PDFApplication fissure sealant with glass ionomer materials effectively prevent the occurrence of dental hard tissue damage. Release of fluoride from glass ionomer can remineralize tooth and make it more resistant to acid. Application of glass ionomer sealant can expect an prevent damage hard tooth tissue on people who consume carbonated drinks in excess. The purpose of this study to determine the effects of immersion material glass ionomer cement fissure sealant on carbonated drinks to the release of fluoride ions . This research is an experimental laboratory with research design the post test only control group design . Glass ionomer material FUJI VII apllied on the buccal premolar and soaked with intervals of 30,60,90, 120 minutes and 24 hours in carbonated drink 50 ml . New replacement soaking solution performed on each interval . Calculation performed on each fluorine soaking solution using a spectrophotometer. Final result were analyzed using Kolmogorov Smirnov and Levene's test, followed by test Two way annova to see the difference between the control and treatment groups and followed by Duncan test to assess the difference between treatments. The results showed that the release of fluoride that has been soaked in a solution of glass ionomer materials . Fluoride content was highest at the beginning of immersion ( 30 minutes ) of 1.43 ppm and decreased significantly ( p > 0.05 ) in the next soaking up the content contained in the lows at the end of immersion ( 24 hours ) of 1.28 ppm. Key word : Carbonated drinks, fissure sealants, glass ionomer, the release of fluorid