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Daya Hambat Ekstrak Kulit Semangka (Citrullus lanatus) Terhadap Pertumbuhan Candida albicans
Get PDFCandida albicans is normal flora found in the oral mucosa in healthy individuals but has opportunistic pathogenic properties. The change in the oral cavity's environmental conditions can cause C. albicans to turn into a pathogen and cause oral candidiasis. Antifungal drugs that are common used for the treatment of oral candidiasis are topical nystatin preparations. Nystatin is an antifungal drug from the polyene group produced by Streptomyces noursei, which is thought to be very effective in treating diseases caused by C. albicans with a success rate 79.6 - 87.5%. The previous study showed that watermelon peel extract contains active compounds of alkaloids, flavonoids, tannins, and saponins. The active compound is known to have antifungal activity. The study aimed to determine the ability of watermelon peel extract to inhibit the growth of C. albicans. The type of research conducted is experimental laboratories using the post-test only control group design. The observations in this study about the inhibitory power of watermelon rind extract (Citrullus lanatus) on the growth of C. albicans showed that there were inhibitory zones of watermelon skin extract on the growth of C. albicans
Pengembangan Biosensor Berbasis Plastik Zona Mikro untuk Skrining Aktivitas Antidiabetes pada Ekstrak Tanaman Obat
Get PDFResearch on the diabetes mellitus (DM) treatment has recently been carried out, especially on discovering antidiabetic agents derived from plants. This study aims to determine the fabrication of microzone plastic-based biosensors, determine the optimal sensor conditions, analysis characteristics, and compare the biosensor with the UV-Vis spectrophotometric method. The results showed that the response time was 15 minutes, the linear range was 500-40000 µg / mL (R = 0.9989). The limit of detection (LOD) was 1109.6 µg / mL, and the limit of quantification (LOQ) was 3698.8 µg / mL. Biosensor filled up the precision parameters with an RSD value of less than 3.7% and an accuracy with recovery in the range of 95-105%. The biosensor is stable in storage at 25 ° C for 270 minutes and at chiller temperature for three days. The antidiabetic activity of the biosensor was compared with the UV-Vis spectrophotometer using the Independent Sample T-test and showed insignificant differences between the two methods
Gambaran Dukungan Keluarga pada Peran Ibu Remaja di Kecamatan Sukowono-Jember
Get PDFAdolescent mothers are a woman around 20 years old who is transitioning between children and adults but has to play a role as a parent. The transition period needs support from the closest family, husband, and closest person and hopefully can make it easier to be a mother to reduce their self-esteem or psychic in accepting the role of being a mother. The form of family support is instrumental support, informational support, support for self-esteem support from social groups. This study aimed to determine the description of family support in the role of adolescent mothers in the Sukowono Subdistrict, Jember Regency. This research used method explorative descriptive and total sampling method with 50 adolescent mothers as respondents. Data were analyzed by univariate analysis. This result showed that the respondents' characteristics mainly were 19 years old, all adolescent mothers worked as housewives (100%), and almost all of the monthly income was less than 1,000,000 (90%). A half of the respondents (50%) received family support from their husbands, parents, or in-laws in suitable categories. Therefore necessary family support is given to adolescent mothers to carry out their roles
Gambaran Derajat Keasaman (pH), Volume, Viskositas dan Kapasitas Buffer Saliva pada Anak Down Syndrome di Sekolah Luar Biasa Kabupaten Jember
Get PDFDown syndrome is a congenital disorder that results in the inhibition of mental and physical development. People with down syndrome experience physiological changes in the flow rate of saliva and its composition. These changes will reduce the function of saliva in protecting teeth. The purpose of this study was to examine the salivary pH, volume, viscosity, and buffer capacity of children with down syndrome in Special Needs School Jember. This study was an observational study on 18 children from 3 Special Schools in Jember. The unstimulated saliva volume was determined by spitting methods, saliva viscosity using Ostwald viscosimeter, and salivary buffer capacity by Erricson methods. The results were the salivary pH was normal tends to be alkaline, the saliva volume was normal tends to low, the saliva viscosity was normal, and the buffer capacity of saliva was good. This will be useful to be taken into consideration for the dental and oral health program of down syndrome childre
Label Pintar untuk Pemonitoran Kesegaran Daging Ayam pada Kemasan
Get PDFChicken meat is one of the commodities consumed by most Indonesian people and has a pH range of 5,5 – 6,0. The smart label has been applied as a chicken meat freshness detector. As dual indicator freshness, two pH indicators have been used, i.e., bromothymol blue (BTB) and methyl red (MR). The objective of this research was to determine chicken meat freshness using a smart label at room temperature. The color change of the smart label was examined by ImageJ software to determine freshness degree using the mean RGB value. The chicken meat was examined every 2 hours for pH and TVB analysis during the 24 hours storage at room temperature. The result showed that color indicator would change according to chicken meat freshness, BTB turned from yellow to blue (mean RGB 210,591 ± 0,376), and MR turned from red to yellow (mean RGB 208,146 ± 0,390). Chicken meat freshness at room temperature decreased as pH increase from 5,68 to 6,11 along with a color change of smart label. Furthermore, the color would change when 0.022 %N of TVB has been reached. Therefore, chicken meat freshness can be determined by using a smart label based on a dual indicator of bromothymol blue and methyl red at room temperature
Hubungan Citra Pelayanan dengan Pemanfaatan Layanan Rawat Inap di Rumah Sakit Jember Klinik Tahun 2018
Get PDFThe role of the hospital’s image greatly influences the success of activities in acting as a hospital. There are five dimensions to measure the image of service through the company image (corporate image): corporate identity, physical environment, contact personnel, service offering, and corporate individuality. The study is a quantitative study aimed at analyzing the image of service and utilization of inpatient services at Jember Klinik Hospital. Results showed that of the 90 respondents, respondents had good ratings of corporate identity (60%), physical environment (68.9%), contact personnel (97.8%), service offering (74.4%), corporate individuality (70%), and service utilization (77.8%). Data analysis showed that the variables which have a significant correlation with the utilization of inpatient services at Jember Klinik Hospital are corporate identity (0.007), physical environment (0.010), service offering (0.009), corporate individuality (0.043), and contact personnel (0.065) has no correlation with the utilization of inpatient services at Jember Klinik Hospital. The study concluded that the assessment of service images at Jember Klinik Hospital is good, but the physical environment variable has a low rating regarding inadequate parking facilities. The strategic location and type of service provided by the hospital are essential factors in the utilization of health services
Level Glukosa Darah pada Mencit Diabetes Setelah Pemberian Ekstrak Rumput Laut Coklat (Phaeophyta)
Get PDFDiabetes mellitus (DM) is a disorder of hyperglycemia and glucose intolerance caused by insulin deficiency or insulin disorder. Insulin hormone functions in the formation of glucose as an energy source. Consequently, glucose accumulates in the blood in DM patients and affects increased free radicals within the cell and oxidative stress. In DM patients with an imbalance of oxidants and antioxidants in his plasm, therefore, patients with DM require a large amount of antioxidants intake. One alternative treatment is seaweed. Brown seaweed contains bioactive components such as polyphenols and carotenoids, which exhibit antioxidants and reduce blood glucose levels. The study aimed to analyze the effect of brown seaweed extract on the blood glucose levels in diabetic mice. The study used a research design of pre and post-test control group design. The study was divided into 4 sample groups, namely the normal group, negative controls (diabetic mice), positive control (diabetic mice + 1.3 mg / 20 gr BB metformin), P1 (diabetic mice + brown seaweed extract). The seaweed dose of 10mg / 20grBB is given daily for 21 days. Blood glucose level checks using Glucometer and strip test (Autocheckâ„¢). Brown seaweed extract has an effect on reducing blood glucose levels in diabetic mice
Hubungan antara Kadar Feritin dengan Malondialdehyde pada Pasien Talasemia β Mayor di RSD dr. Soebandi Jember
Get PDFRepeated blood transfusions, increased iron absorption, and ineffective erythropoiesis in major β thalassemia patients lead to iron overload characterized by elevated ferritin levels. Free iron will catalyze reactive oxygen species (ROS) formation by Fenton reaction that cause oxidative stress. Malondialdehyde (MDA) is the lipid peroxidation end product used to measure the oxidative stress. This study aimed to determine the correlation between ferritin levels and MDA levels in major β thalassemia patients at dr. Soebandi Hospital Jember. An analitic observational study with cross sectional study design which the subjects were 15 patients with major β thalassemia in the Pediatric Department at dr. Soebandi Hospital Jember who met inclusion and exclusion criteria. Ferritin levels measured by Enzyme-Linked Fluorescent Immuno Assay (ELFA) method and MDA levels measured by Thiobarbituric Acid Reactive Substances (TBARS) method using spectrophotometer at 535 nm. Data was analyzed with Shapiro Wilk normality test and Pearson correlation test. The mean of ferritin levels was 3540,46±3925,37 ng/mL and MDA levels was 4,77±2,03 nmol/mL. The result showed that there is strong positive correlation between ferritin levels and MDA levels with p value=0,001 and r=0,786 in major β thalassemia patients at dr. Soebandi Hospital Jember
Pengaruh Therapeutic Exercise Walking terhadap Sirkulasi Darah Perifer pada Pasien Diabetes Melitus Tipe 2 di Kelurahan Gebang Kecamatan Patrang Kabupaten Jember
Get PDFPathological change experienced by patients with type 2 diabetes mellitus is impaired peripheral blood circulation, especially in the lower limbs and feet. Peripheral blood circulation can be examined by measuring Ankle Brachial Index (ABI). Therapeutic exercise walking is one of physical activities which can improve blood circulation. This research goal was to analyze the effect of therapeutic exercise walking on peripheral blood circulation in patients with type 2 diabetes mellitus. The research design was randomized control group pretest-posttest design. The sample size was 15 respondents as control group and 15 respondents as treatment group. Data was analyzed by using dependent t-test and independent t-test with significant level of 0.05. This result showed a significant increase of ABI after therapeutic exercise walking in the treatment group (p= 0.001). However there was a significant decrease of ABI between pretest and posttest in control group (p=0.010).Independent t-test indicated a significant difference of ABI between treatment group and control group (p=0.000). So, it can be concluded that there is an influence of therapeutic exercise walking on the peripheral blood circulation in patients with type 2 diabetes mellitus. Nurses should apply therapeutic exercise walking to improve peripheral blood circulation in patients with type 2 diabetes mellitus.
Keywords: type 2 diabetes mellitus, therapeutic exercise walking, ankle brachial inde
Pengaruh Penyuluhan Metode Demonstrasi terhadap Pengetahuan Infeksi Nosokomial pada Pasien Rawat Inap
Get PDFNosocomial infections, known as Healthcare Associated Infections (HAIs), occur throughout the world. The patient's family has an important role in the prevention of Nosocomial Infection by improving handwashing behavior well, but the implementation of handwashing in the patient's family has not run optimally because many patient families do not know how to wash their hands properly. This study used a pre-experimental design with the design of one group pretest-posttest test design, the sample performance in this study was carried out by a Non-probability sampling technique with a purposive sampling analysis of this study using the Wilcoxon Signed Rank Test. The subjects in this study were families of hospitalized patients in the Flamboyan Room Negara Hospital which numbered 92 people. The measuring instrument used in this study used a knowledge questionnaire on nosocomial infections. There were influences before and after the extension of the demonstration method with the family characteristics of inpatients, most of the education level was junior high school, with the most adult age range 26-45 with a male gender. There is an influence on the extension of the demonstration method on the knowledge of nosocomial infections and this counseling can increase the knowledge of families of inpatients in the Flamboyan Room Negara Hospital in 2019