JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan"
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The Efficacy Of Anatomical Skeletal System Guidebook For Medical Students At Universitas Jambi
Full text linkABSTRACT
Background: Medical students need to have good anatomy knowledge. FKIK UNJA changed the learning system to hybrid in response to the COVID-19 pandemic. An update on the skeletal system anatomy practicum guidebook is needed to improve student’s understanding.
Objective: This study aims to determine the effect of using the skeletal system anatomy practicum guidebook on the anatomy grade of first-semester students Faculty of Medicine and Health Science Jambi University.
Methods: This study applied a quasi-experimental method with a pretest-posttest control group design. The samples were 120 first-semester Jambi University medical students year 2022/2023 who participated in the axial skeleton anatomy practicum.
Results: Students with the practicum guidebook pre-test mean grades were (40,58±11,36) and post-test mean grades were (75,74±7,26). Students without practicum guidebook pre-test mean grades were (27,49±13,89) and post-test mean grades were (72,92±5,13). There was a significant difference between the students with and without the practicum guidebook (p-Grades 0,030).
Conclusion: The use of the skeletal system anatomy practicum guidebook significantly improves first-semester medical students’ anatomy grades.
Keywords: Anatomy Grades, Complete Anatomy, Hybrid, Practicum Guidebook, Skeletal Syste
CORRELATION OF LYMPHOCYTE-MONOCYTE RATIO AND MORTALITY OF COVID-19 INTENSIVE CARE UNIT PATIENTS: PRELIMINARY STUDY
Full text linkBackground: The world faces a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCov-2). Because of the limitations as a developing country, Indonesia needs to do its activities efficiently in time,money, and human resource. This research aims to accurately determine a concrete mortality predictor to predictthe patients' mortality. One of the mortality predictors is the lymphocyte-monocyte ratio (LMR).Method: This research is observational analytic research using a cross-sectional study method. Data obtainedfrom the Medical Record & Casemix Room of RSUD Raden Mattaher.Results: Out of 115 samples, most patients were male (65 patients). The patients' age group was mainly youngerthan 65 (79%). The most common comorbidity was diabetes mellitus (43 patients). The correlation between LMRand mortality rate to be weak with the following results: Pearson coefficient(p=0.045), gamma coefficient (P=0.325),Somers' D test (P=0.167), odds ratio (1.833), AUC (58%), specificity (58%), sensitivity (56%), and intersection point(1,79).Conclusions: There is a weak correlation between LMR and the mortality rate of COVID-19 patients in RSUDRaden Mattaher.Keywords: Characteristics of COVID-19 patients, comorbidity of COVID-19 patients, LMR (Lymphocyte-monocyteratio), a mortality rate of COVID-19 patients
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN KUSTA DI WILAYAH KERJA PUSKESMAS MUARA SABAK TIMUR KABUPATEN TANJUNG JABUNG TIMUR
Full text linkBackground: Tanjung Jabung Timur Regency is ranked first in leprosy cases in 2019 with a total of 36 cases. In 2020 East Tanjung Jabung Regency recorded 14 new cases of leprosy. The Muara Sabak Timur Health Center is one of the health centers with the highest leprosy with a total of 25 cases until 2020.
Objective: The purpose of this study was to determine the factors associated with the incidence of leprosy in the working area of the Muara Sabak Timur Health Center.
Method: The design of this study uses a case control approach. The sample in the study used a 21 case group samples and 21 control group samples.
Results: From the statistical test results contact history variable p-value 0.147 (OR 1.105), humidity variable p-value 0.334 (OR 1.875), ventilation area variable p-value 0.001 (OR 10.625), occupancy density variable p-value 0.000 (OR 15.438), clean water availability variable p-value 0.204 (OR 2.273), toilet ownership variable p-value 0.040 (OR 4.500), house floor variable p-value 0.707 (OR 1.328), and personal hygiene variable p-value 0.013 (OR 5,200).
Conclusion: leprosy is highly contagious, especially in conditions of poor personal hygiene, crowded housing, and latrines and ventilation that do not meet health requirements.
Keywords: Leprosy, personal hygiene, ventilation, humidity, residential densit
DETECTION OF MecC GENE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLATES AT JAMBI CITY HOSPITALS
Full text linkBackground: Methicillin Resistant Staphylococcus aureus (MRSA) has a low-affinity to penicillinbinding protein (PBP) in B1subclass, and is often known as PBP2a or PBP2, characterized by the presence of mecA gene. Further research found MRSA isolates that did not contain the mecA gene. They have mecA homolog gene (mecALGA251) which has similarity with the classic mecA gene, then named the mecC gene. The discovery of MRSA mecC in humans still low in prevalence.Objective: This study aimed to detect mecC gene in MRSA isolates at hospitals in Jambi.Method: This study was a descriptive study conducted in the Biomedical and Biomolecular Laboratoryof Faculty of Medicine and Health Sciences, Jambi University.Results: A total of 117 clinical specimens in the forms of purulent wound swabs of the inpatients athospitals in Jambi City has been cultured on the MSA agar. Then yellowish samples (43 isolates) were screened for susceptibity of cefoxitin (30 µg) by disc / diffusion test and the presence of mecA, femB and mecC genes by conventional PCR. There were 22 (51.16%) samples contained mecA, 2 (4.65%) samples had also femB gen, 1 (2.32%) samples contained femB gene only and none contained the mecC gene.Conclusion: There was no mecC gene had been found in MRSA isolates in Jambi.Keywords: PCR, MRSA, MecC, MecA, Fem
Pituitary Apoplexy Induced by Anticoagulant Therapy in Patient with Acute Coronary Syndrome
Full text linkPituitary apoplexy, defined as bleeding or infarct on pituitary gland which often occurs in undiagnosed pituitary tumour. Some of the mechanisms thought to trigger pituitary apoplexy are fluctuations in blood pressure, hormonal stimulation of the pituitary gland, coagulation disorders or vascular disorders.
We reported the case of a male patient, aged 73 years from India who came to the emergency department with complaints of chest pain in the last four hours. Electrocardiographic (ECG) and laboratory examination results lead to an acute coronary syndrome (ACS) event. Patients are given blood thinners in the form of fondaparinux, aspirin, and clopidogrel. On the 4th day of hospitalization, the patient experienced a severe headache, projectile vomiting, and double vision. Radiological examination reveals a pituitary tumour with signs of diffuse haemorrhage compressing the optic chiasma, suggesting an apoplexy of a pituitary tumour. Hormone function tests show a non-functioning pituitary tumour. The blood thinners were discontinued, then vitamin K and dexamethasone were given to reduce the patient's symptoms. After a few days, the headaches and double vision began to improve. Another MRI of the head was done and the result shoed that the mass remained the same and the bleeding did not expand.
It is known that patients with pituitary tumors are at risk of experiencing bleeding after administration of blood thinners. The presence of a pituitary tumour may be a relative contraindication to the use of dual antiplatelets and anticoagulants in acute coronary syndromes especially in group with renal or liver comorbidities
ABO Blood Group: Risk factors for malaria in hypoendemic areas?
Full text linkABSTRACT
Background: Malaria is a parasitic infectious disease that is transmitted by vectors. This disease can cause death, especially in babies, toddlers and pregnant women. This research was conducted to prove whether there was a relationship between blood group and the occurrence of malaria infection.
Methods: The sample was people who permanently reside in the research area and have risk factors for exposure to malaria. Diagnosis was made through microscopic examination. Blood type was tested using the slide method.
Results: The most common cause of malaria was Plasmodium vivax. There were no significant differences between etiology, clinical symptoms, hemoglobin levels and parasite density with ABO blood group. This study found no significant differences between ABO and malaria blood types.
Conclusion: ABO blood type cannot be used as a risk factor in hypoendemic areas which have the majority of vivax malaria sufferers
The Relationship Between Leucocytes and Bacterial Count in The Wound Swab Sample with Colony Counting In Wound Tissue Infection
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Background: Wound tissue infection is a problem in developing countries. The cause of the infection must be known, so that appropriate antibiotics are given for that required microbiological examination. The number of Polymorphonuclear leukocytes (PMN) >25/HPF and the number of colonies >105/Colony Forming Unit (CFU) determine the occurrence of infection. Proving the relationship between the number of leukocytes and bacteria in the wound swab sample to the number of colonies in superficial Surgical site infection (SSI).
Methods: This study was an Observational analytical research design with 35 samples of superficial SSI. Microscopic examination: gram stain to see the number of leukocytes and bacteria in a large field of view. Culture examination: number of colonies, identification of microorganisms, and patterns of antibiotic sensitivity with automatic machines. Statistical analysis for the relationship between the number of leukocytes and bacteria to the number of colonies was Chi-square and logistic regression.
Results: Superficial SSI samples were more common at the age <60 years, with malignancy comorbid. The most common cause of infection is Escherichia coli. The results of the Chi-square test showed that the number of leukocytes (p=0.017) and the number of bacteria (p=<0.01) were related to the number of colonies, and logistic regression tests found that the number of bacteria was significant to the number of colonies (p=0.010, 95% C1: 0.030–0.624).
Conclusion: The number of bacteria associated with the number of bacterial colonies in patients with superficial SSI
The Correlation Of Ujian Tahap Bersama (UTB) With Grade Point Average (GPA)
Full text linkABSTRACT
Background: There are several assessments in medical education in Indonesia. Currently, as a formative assessment at the preclinical level, UTB (Ujian Tahap Bersama) is being proposed to control the quality of medical education graduates.
Objective: This study aims to determine the correlation between UTB scores and Grade Point Average (GPA).
Methods: This study was an analytic study with a cross-sectional design using a total sampling technique. The sample of this study was students participating in UTB Stage 1 or UTB Stage 2 at the Medical Study Program, Faculty of Medicine and Health Science Jambi University.
Result: The average UTB Stage I score was 36.83±8.86, and the average UTB Stage II score was 45.42±7.43. There was a correlation between UTB Stage I score and GPA (p <0.001), with a coefficient correlation of 0.677. There was a correlation between UTB Stage II score and GPA (p<0.001), with a coefficient correlation of 0.575.
Conclusion: There was a strong correlation between UTB Stage I scores and GPA and a moderate correlation between UTB Stage II scores and GPA.
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Instructor’s Role In The Conduction Of Basic Clinical Fitness In The Clinique Fitness Laboratory / Skills Laboratory
Full text linkABSTRACT
Teaching clinical skills is a must in the 21st century. Medical school is required to make its graduates as skilled and professional doctors need a lot of support such as clinical skill laboratory facilities (Skills Lab) and instructors. Students need to be given sufficient opportunities to practice basic clinical skills in a place that is comfortable, safe and controlled without fear of harming patients and can be monitored and assessed in accordance with the expected competencies. Clinical skill instructors are the cornerstones of basic clinical skills teaching process. The role of the instructor includes building two-way relationships for each individual student, giving feedback, becoming role models so that students will be responsible for carrying out each procedural step of clinical skills. Their role is very important in guiding and facilitating the students to practice clinical skill, making sure their skills progress, and preparing them to obtain the predetermined competency as a doctor
EVALUASI SURVIVIN DAN MAMMALIAN TARGET OF RAPAMYCIN COMPLEX-1 SERTA KORELASINYA PADA AKNE VULGARIS
Full text linkBackground: Survivin is a member of the apoptosis inhibitory protein family, a protein molecule important for the regulation of mitosis and inhibition of apoptosis and also plays a role in certain physiological processes and pathological conditions such as carcinogenesis in human cells/organs. Several studies have shown that survivin plays a role in the pathogenesis of acne vulgaris and post-inflammatory acne scarring. Mammalian target of rapamycin complex-1 (mTORC1) is a regulator of cell growth, proliferation and metabolic homeostasis, and mTORC1 signaling regulates survivin via the kinase pathway.
Objectives: This study aimed to assess the correlation of survivin levels with mTORC1 and the severity of acne vulgaris.
Methods: This research was a cross-sectional study. Venous blood samples of mild, moderate, and severe AV patients were 20 people each, ELISA examination was performed.
Result: The results showed that serum levels of survivin and mTORC1 had a correlation with the severity of AV (p<0.05), while the correlation between survivin and mTORC1 was not significant (p>0.05).
Conclussion: This study proves that increased survivin and mTORC1 are associated with increased severity of acne vulgaris, but the relationship between survivin and mTORC1 needs further investigation.
Key words: survivin, mammalian target of rapamycin complex-1, akne vulgari