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Die Sächsische Gartenakademie: Informations- und Weiterbildungsangebot 2019
No full textDie Gartenakademie des Sächsischen Landesamtes für Umwelt, Landwirtschaft und Geologie wendet sich mit einem vielfältigen Weiterbildungsangebot an alle Freizeitgärtnerinnen und Freizeitgärtner. Der Flyer bietet einen Überblick über das gesamte Angebot der Gartenakademie im Jahr 2019.
Redaktionsschluss: 31.08.201
HIV/AIDS im Freistaat Sachsen / Staatsministerium für Soziales und Verbraucherschutz, Freistaat Sachsen: Jahresbericht ...
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Evaluation of the Blood Neutrophil-to-Lymphocyte Ratio (NLR) as a Diagnostic and Prognostic Biomarker in Dogs with Portosystemic Shunt
No full textRoutine blood parameters (e.g., the neutrophil-to-lymphocyte ratio, NLR) are
valuable tools for diagnosing inflammatory, infectious, and metabolic conditions. Dogs with con-
genital liver shunts show evidence of generalized inflammation and clinical signs that may overlap
with those of other diseases. Therefore, the potential diagnostic and prognostic value of blood cell
ratios, including the NLR, was investigated in 106 dogs with congenital liver shunts and compared
to two other disease groups. An association was detected between the blood NLR and systemic
inflammation but not with any characteristics of the liver shunt or clinical correlates. The NLR
could not distinguish the three disease groups, dogs with liver shunts that were either medically or
surgically treated, or dogs either with successful shunt surgery or those with surgical complications.
However, lower NLRs (<2.53) were predictive of dogs with liver shunt surgery requiring only one
PSS closure session rather than two consecutive surgeries. Thus, evaluating the blood NLR might
be clinically useful in dogs with liver shunts. Although this parameter may have little value in
distinguishing dogs with a liver shunt from dogs with other diseases, it appears to be predictive for
the number of surgical sessions required for shunt closure via ligation.The neutrophil-to-lymphocyte ratio (NLR) can help in assessing inflammatory diseases,
sepsis, and chronic hepatic conditions in humans. Dogs with congenital portosystemic shunts (PSSs)
have signs of generalized inflammation, and the clinical signs can overlap with other conditions,
including hypoadrenocorticism (HOC). Thus, the potential diagnostic and prognostic value of leuko-
cyte ratios as surrogate markers was assessed in a retrospective case–control study including 106 dogs
diagnosed with PSSs. The disease control groups were dogs with parenchymal hepatopathy (PH;
n = 22) or HOC (n = 31). In the PSS dogs, the blood NLRs were associated with the severity of
systemic inflammation but not with the shunt type, hepatoencephalopathy, systemic infection, or
hypoglycemia. The baseline NLRs did not differ between the three disease groups, between medically
and surgically treated PSS dogs, or between those with successful PSS ligation and dogs experiencing
peri-/post-surgical complications. However, dogs requiring two consecutive surgical interventions
had significantly higher NLRs, and an NLR of <2.53 distinguished dogs with successful shunt ligation
in one surgery from those requiring two consecutive surgeries for PSS closure. The blood NLR might
be a useful clinicopathologic variable in PSS, but its value in helping differentiate PSS from HOC
cases appears low. Integrating the NLR into a diagnostic algorithm may allow for a prediction of the
number of surgical interventions required
Der Blick in die Quellen: Ländliches Judentum im Elsass mit Berücksichtigung der jiddischen Sprache (19.–20. Jahrhundert)
No full textAge-Related Differences in Takotsubo Syndrome: Results From the Multicenter GEIST Registry
No full textBackground
The role of age in the short‐ and long‐term prognosis of takotsubo syndrome (TTS) is controversial. The aim of the present study was to evaluate age‐related differences and prognostic implications among patients with TTS.
Methods and Results
In total, 2492 consecutive patients with TTS enrolled in an international registry were stratified into 4 groups (<45, 45–64, 65–74, and ≥75 years). The median long‐term follow‐up was 480 days (interquartile range, 83–1510 days). The primary outcome was all‐cause mortality (in‐hospital and out‐of‐hospital mortality). The secondary end point was TTS‐related in‐hospital complications. Among the 2479 patients, 58 (2.3%) were aged <45 years, 625 (25.1%) were aged 45 to 64 years, 733 (29.4%) were aged 65 to 74 years, and 1063 (42.6%) were aged ≥75 years. Young patients (<45 years) had a higher prevalence of men (from youngest to oldest, 24.1% versus 12.6% versus 9.7% versus 11.4%; P<0.01), physical triggers (46.6% versus 27.5%, 33.9%, and 38.4%; P<0.01), and non‐apical forms of TTS (25.9% versus 23.7%, 12.7%, and 9%; P<0.01) than those aged 45 to 64, 65 to 74, and ≥75 years. During hospitalization, young patients experienced a higher rate of in‐hospital complications (32.8% versus 23.4%, 27.4%, and 31.9%; P=0.01), but in‐hospital mortality was higher in the older group (0%, 1.6%, 2.9%, and 5%; P=0.001). Long‐term all‐cause mortality was significantly higher in the older cohort (5.6%, 6.4%, 11.3%, and 22.3%; log‐rank P<0.001), as was long‐term cardiovascular mortality (0%, 0.9%, 1.9%, and 3.2%; log‐rank P=0.01).
Conclusions
Young patients with TTS have a typical phenotype characterized by a higher prevalence of male sex, non‐apical ballooning patterns, and in‐hospital complications. However, in‐hospital and long‐term mortality are significantly lower in young patients with TTS
Of Genre, System and Process: Music Theory in a “Global Sonorous Space”
No full textDrawing on Jean-Luc Nancy’s concept of a “global sonorous space”, this essay considers the radical nature of today’s listening environment; an environment saturated with musics from around the world. Made possible by such technologies as recording, ipods and the internet, any music can be anywhere at any given time. This situation has profound implications for traditional notions of genre in which musical systems and cultures are treated as isolated from one another; namely it can be argued that these systems are far more interconnected and dynamic than is generally thought. Following Michael Tenzer’s speculation about the potential for a “world music theory”, a conceptual space is laid out in which such a theory could be founded. This space is modelled upon concepts developed by Gilles Deleuze and Félix Guattari such as the rhizome, smooth space and the idea of unstable systems “at the edge of chaos”
Eine »Musiktheorie der Gesellschaft«: Hat die Systemtheorie der Musiktheorie etwas zu sagen?
No full textAn increasing number of publications in recent years show that the system theory of Niklas Luhmann is not an unknown topic in music theory any more, although as yet there has been no attempt at a comprehensive discussion of its potential to tackle music-theoretical questions. In musicology, on the contrary, the discussion of Luhmann’s theory seems to have peaked already. System theory here is either praised as the most promising method for future research or entirely rejected as a method inadequate for music. This essay provides an overview on applications of Luhmann’s system theory in music theory. Generally, there are two ways to interpret music in the context of social systems that can either focus on communication about music or regard music itself as a subsystem of modern society. Music also can be unterstood as a system that intertwines with the listener’s psyche. These considerations enable a discussion of the connections between system theory and music theory in general. It becomes clear that Luhmann’s concept of “self-reference” can enrich music research. It might enhance, for example, a reflection of methodologies in music theory and thus contribute to a differentiation of different music-theoretical (sub-)systems: between music theory as an artistic or a scholarly system, between music theory and musicology or between music as a psychological, social or multiply organized autopoetic system. Such a differentiation in turn might be a first step towards observing and interpreting problems of research or teaching. System theory provides a research tool that offers possibilities to isolate methodological problems in new and illuminating ways
Mitwelt im Wandel wahrnehmen, verstehen und gestalten: Bildungpotentiale des technischen Gestaltens in Lehrer:innenbildung, Forschung und Schulpraxis
No full textImplizite Theorie
No full textThe selection and evaluation of historical theoretical sources depend considerably on our interests and expectations. The importance of basso continuo remains underestimated today, while sources which seem to pave the way for chord-inversion, fundamental bass and “modern” harmony systems are often overrepresented. This article attempts to show that many didactic writings from the 16th to the 18th century contain an implicit theory, which can be highly useful today for practical exercises as well as for analysis. This implicit theory is built upon general concepts orientated towards the surface of composition and not towards hidden structural strata. The metaphor of a musical surface as contrasting to depth and height is derived from Gilles Deleuze’s philosophy and used as a global interpretation of the history of music theories. “Musical surface” here designates the intervallic design of multi-part structures, above all the design of the outer voices, demonstrated prototypically by examples from Henry Purcell’s Dido and Aeneas. The art of designing the musical surface serves as the main criterion of a composer’s craftsmanship in numerous treatises. The “theory” documented in these treatises has to be reconstructed today, as it is often not entirely verbalized. The most common didactic tool in these implicit theories is the exemplum. The practical use of exempla helps to transform an implicit into an explicit theory and as a result might also help to reconstruct historic teaching methods. This is exemplified by the discussion of passages from treatises by Christopher Simpson (A Compendium of Practical Musick, 1667) and Giovanni Paisiello (Regole per bene accompagnare il partimento, 1782). This practically oriented approach makes today’s didactics of historical musical styles similar to experimental archeology