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カエル舌水受容器の化学修飾 1. NEM, TNBSおよびNQSの作用
application/pdfChemical modification of protein was applied to a frog water receptor to learn whether or not sulfhydryl and amino residues are indispensable to the receptor site of Ca response. N-ethylmaleimide (NEM), which is known to modify sulfhydryl residues of protein, was shown to inhibit Ca response irreversibly without affecting responses of tactile receptors, indicating that the recepter molecule responsible for Ca response is protein. Trinitrobenzene sulfonate (TNBS) and β-naphthoquinone-4-sulfonate (NQS), which are known to modify amino residues of protein, did not inhibit Ca response irreversibly, indicating that amino residues are not indispensable to the receptor site of Ca response.journal articl
Environmental Survey of Dental Treatment for Intensive Care Infants under General Anesthesia
application/pdfTo investigate positive inhibitory measures against severe caries thought to develop in nursing infants, we examined the nursing environment of intensive care infants under general anesthesia at Matsumoto Dental College's Department for dental treatment from January 1989 through December 1993.journal articl
実験的歯の圧下時に伴う歯根尖吸収 : 組織化学的観察
application/pdfOrthodontic treatment commonly causes apical root resorption (AP). Especially, duration of intrusive force have a significant associaion with AP. However, there has been a little information concerning about the histological changes of periodontal tissues during continuous intrusion of tooth. The aim of this study was to evaluate changes of periodontal tissues during experimental intrusive force by histological and histochemical techniques. Intrusive force by labial-arch appliance on the maxillary left central and lateral incisors of male Japanese monkeys (Macaca fusucata) were applied on 1, 3, and 6 months. After three different experimental durations, maxillary anterior bone segments were dissected out, decalcified, and prepared for histochemical study. One month after treatment, many resorption lacunae were found not only apical but lateral surface of the roots. Numerous mononuclear and multinucleate cells which showed tartrate resistant acid phosphatase (TRAP) activity were observed adjacent to the resorpted root surface. After 3 months, most of the resorption lacunae of lateral root surface had been repaired. In the apical resion, However, TRAP positive cells were observed on the root and alveolar bone. The periodontal membrane space was significantly widen. Numerous blood vesseles occupaied the space of periodontal menbrane. These histological configurations were also found after 6 month treatment. The present study suggested that intrusive force might continuously stimulate resorptive activity in apical region of teeth, and induce AP.journal articl
歯の形成とプロテアーゼの作用
application/pdfDuring tooth development in tooth germs, a chain of reciprocal interactions between the epithelial and mesenchymal tissue regulates both morphogenesis and cell differentiation. Several extracellular matrix proteins such as fibronectin, tenascin, syndecan, collagens, and enamel proteins are thought to be involved in the tooth developing process on a timed schedule. The turnover of these proteins can be broken down with proteases in the tooth germs. In this review article, proteases related to degradation of extracellular matrix proteins including their properties are summarized.journal articl
松本歯科大学病院矯正科に来院した患者の実態調査 : 1986年~1991年
application/pdfThe statistical analysis of district distribution, number, and type of malocclusion in orthodontic patients at Matsumoto Dental College Hospital has been reported upon every five years during the period from 1972 to 1986. The current study analysed records of the most recent five year period of January 1986 through December 1991 and then compared the findings with those of previous reports. The results obtained were as follows: 1. 942 patients, consisting of 344 males and 598 females were examined to show a 4:6 ratio of males to female. 2. The district distribution of patients showed that most patients came from the local area to our clinic. 3. The number of patients were almost equal to that of the previous five years. 4. The number of patients was highest in the month of March. 5. With regards to the distribution of malocclusion types, the percentage of mandibular protrusion and anterior crowding increased for both sexes. This trend was also observed in previous reports. 6. The age distribution showed that more than 30% of the total number of patients were pupils between 9 and 11 years old. 7. In the present survey, females were more than males in all age groups. Also, the second peak of patient's increase was observed in older than 15 years paticularly in females.journal articl
松本歯科大学所蔵の野口英世の伝記(第3報)
application/pdfIn the previous papers 176 books and journals regarding the biography of Dr. Hideyo Noguchi were reviewed (Matsumoto Shigaku, Vol.13, pp.1~34, 1987: Vol.15, pp.217~231, 1989). In addition to these, 58 books and journals, including the following 3 important books, were introduced in this paper. 1) Hokari, Y.: A Tasteful Biography of Great Men. Daikyosha, Tokyo, 1931 2) Masaki, F.: A Benefactor of the Humans, Hideyo Noguchi. Shinchosha, Tokyo, 1936 3) Kobayashi, S.: Memories of Hideyo Noguchi. Iwanami-Shoten, Tokyo, 1941journal articl
Bioprogressive Therapyを用いた上顎前突の2治験例
application/pdfThis article presents two cases of maxillary protrusion. Patients in mixed dentition were treated by bioprogressive therapy. In the first case headgear was applied for orthopedic alteration and in the second case headgear was applied for the maximum anchorage of buccal segments. In both cases visual treatment objectives (V. T. O.) were almost achieved. As a result, patients attained proper chin control, stable occlusions, and favorable profiles. It was recognized that the V. T. O. was valuable to forecast the growth of the patient and the anticipated effects of treatment, as well as to evaluate the results achieved at the end of treatment.journal articl