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象牙芽細胞の枯渇は象牙芽細胞分化と象牙質形成を誘導する
Get PDF松本歯科大学大学院歯学独立研究科博士(歯学)学位申請論文；硬組織疾患制御再建学講座(主指導教員：各務 秀明教授）application/pdfothe
吸収性縫合糸Vicryl® とVicryl rapide® に対するラット皮下組織反応の比較検討
Get PDF松本歯科大学大学院歯学独立研究科博士（歯学)学位申請論文;硬組織疾患制御再建学講座（主指導教員:岡藤 範正教授）application/pdfothe
ガミースマイルを伴う矯正治療患者における口唇運動の三次元解析
Get PDF松本歯科大学大学院歯学独立研究科博士（歯学）学位申請論文;健康増進口腔科学講座（主指導教員:吉成 伸夫教授）application/pdfothe
松本歯科大学病院におけるチタン金属冠の実態調査
Get PDFapplication/pdfConsidering the presence of metal allergies and the sharp rise in the prices of precious metals, full–coverage restorations made of titanium have been covered by Japanese insurance since June 1, 2020. The clinical application of these restorations is expected to increase in the future. However, due to its high melting point and high affinity to oxygen at high temperatures, titanium has not been widely used in prosthetic clinical practice. This study aimed to survey the actual use of full–coverage metal restorations at Matsumoto Dental University Hospital. Patients who had full–coverage metal restorations placed on their molars from June 1 to December 28, 2020, were consecutively enrolled, and data on the type of metal, placement site, and time were recorded. Besides, the dentists who used titanium restorations (Ti–Rs) were given a questionnaire. We asked them to rate their impressions of Ti–Rs in comparison with full–coverage restorations made of Ag–Pd–Cu–Au alloy (Pd–R) in six categories, including occlusal adjustment, polishing, and luting operations. In all, 338 molars received full–coverage metal restorations. Ti–R was used in 33 cases and Pd–R in 305 cases; 14 upper and 19 lower, 12 first molars, 18 second molars, and 3 third molars received Ti–Rs, while 137 upper and 168 lower, 174 first molars, 174 second molars, and 3 third molars received Pd–Rs. Seven dentists responded to the questionnaire survey. Many dentists stated that Ti–R was more challenging to use than Pd–R for occlusal adjustment, polishing, and adjustment time. On the other hand, most of them stated that the luting process was similar for both. Besides, Ti–R was favorably evaluated in terms of metal allergy. The number of patients who received Ti–Rs increased during the study period, suggesting that Ti–Rs will be a commonly used metal allergy–friendly prosthetic in the future. We plan to continue the survey and study the prognosis.journal articl
Cryopreserved Spontaneous Spheroids from Compact Bone-Derived Mesenchymal Stromal Cells for Bone Tissue Engineering
Get PDF松本歯科大学博士（歯学）2021甲第239号application/pdfSpontaneously formed spheroids from mouse compact bone-derived mesenchymal stromal cells (CB-MSCs) possess enhanced stemness and superior plasticity. In this study,the effect of cryopreservation on viabil ity,stemness,and osteogenic differentiation capability of spontaneous CB-MSC spheroids were investigated.CB-MSCs were isolated from mouse femur and tibia. Spheroids were cryopreserved with various concentra tions of dimethyl sulfoxide (DMSO). After thawing,the number of living and dead cells was measured.The expression levels of stem cell markers and osteogenic marker genes were analyzed. The cryopreserved and noncryopreserved spheroids were transplanted in mice with a beta-tricalcium phosphate as a scaffold to evaluate the in vivo bone-forming capability.The percentage of living cells was highest when 5% DMSO was used as a cryoprotectant,confirmed by the number of dead cells.The expression of stem cell marker genes and osteogenic differentiation capability were maintained after cryopreservation with 5% DMSO. The cryopre served spontaneous CB-MSC spheroids showed remarkable new bone formation in vivo,identical to that of the noncryopreserved spheroids even without osteogenic induction. The cryopreserved spontaneous CB-MSC spheroids retained stemness and osteogenic differentiation capability and highlight the utility of spontaneous CB-MSC spheroids as ready-to-use tissue-engineered products for bone tissue engineering.doctoral thesi
エナメルマトリックスタンパク質を用いた歯周組織再生療法に対するEr:YAG レーザー照射の有効性
Get PDF松本歯科大学大学院歯学独立研究科博士（歯学）学位申請論文;健康増進口腔科学講座（主指導教員:吉成 伸夫教授）application/pdfothe
松本歯科大学第3学年保存修復学における共同学修の試みとその学修効果
Get PDFapplication/pdfThe one–way passive lecture style of teachers leads to little long–term knowledge retention, and it is difficult to develop an ability to analyze/solve problems based on the knowledge possessed. We attempted to adopt active learning methods in Operative Dentistry education, in order to make students aware of their lack of knowledge, lack of understanding, and misunderstandings, further guide them to correct answers through collaborative work in groups, and deepen mutual understanding. This paper introduces our attempt and summarizes evaluations from students according to a post–implementation questionnaire. A yes/no test was conducted twice at two of the 30 lectures on Operative Dentistry in the third grade of Matsumoto Dental University in the school year of 2019. After testing, 3 or 4 students were randomly grouped and each answer was considered by them in a primary small group discussion (SGD). In addition, the two groups were combined and a secondary SGD was performed to consider the answers of both groups. After the secondary SGD, an anonymous questionnaire was given to the students who took the course. We also surveyed foreign students regarding their impressions of SGD in the Japanese language. More than half of the students answered that this exercise was meaningful. More than 90% of the students answered that they could more clearly comprehend their lack of knowledge. In addition, more than 90% of the students answered that they learned how to voluntarily look up information to solve problems in textbooks. More than half of the international students answered that the exercise helped improve their Japanese language. Students listening to the opinions of others, clarifying gaps in knowledge, searching for information in textbooks and clarifying it, and sharing the obtained knowledge with each other promoted their motivation for learning. It also contributed to improving the Japanese language skills of international studentsjournal articl
上顎前歯部に3本の過剰歯を認めた1例
Get PDFapplication/pdfWe treated a male elementary School student with 3 supernumerary teeth in the maxillary incisor region detected by radiographic examination.1. The patient underwent radiography for detailed evaluation at dental clinic, was found to have 3 supernumerary teeth in the maxillary incisor region, and was referred to our department.2. There was nothing of note regarding the patient’s history of systemic disorders.3. The patient was aged 7 years and 11 months at the time of the first examination,when the Hellman dental developmental stage was IIC.4. The maxillary right deciduous central incisor was present, and the maxillary left central incisor had already erupted. 5. Three–dimensional examination by radiography and three–dimensional examination using cone–beam CT showed 3 supernumerary teeth and prolonged retention of the maxillary right deciduous central incisor, and ectopia and eruption disorder of the maxillary right central incisor were confirmed.6. At the age of 8 years and 2 months, the maxillary right deciduous central incisor, the maxillary right deciduous lateral incisor and supernumerary teeth were extracted under general anesthesia.7. The postoperative course has been uneventful, but we have decided to continue periodic management because of ectopia of the maxillary right central incisor.journal articl