20518 research outputs found
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Expected Future Precipitation in Central Iraq Using LARS-WG Stochastic Weather Generator
No full textThe Middle East (ME) is characterized by its water shortage problem. This region with its arid climate is expected to be the most vulnerable in the world to the potential impacts of climate change. Iraq (located in ME) is seriously experiencing water shortage problem. To overcome this problem rain water harvesting can be used. In this study the applicability of the long-term weather generator model in downscaling daily precipitation Central Iraq is used to project future changes of precipitation based on scenario of seven General Circulation Models (GCMs) outputs for the periods of 2011-2030, 2046-2065, and 2080-2099. The results indicated that December-February and September-November periods, based on the ensemble mean of seven GCMs, showed an increasing trend in the periods considered; however, a decreasing trend can be found in March, April, and May in the future
Factors affecting UK physically disabled children and young people participating in mainstream out-of-school activities: the children, young people and family perspective
No full textAims of study: To ascertain what out-of-school activities C&YP currently engage in and to determine the facilitators and barriers to participatio
Factors affecting UK physically disabled children and young people participating in mainstream out-of-school activities: Focus on personal care and training
No full textAims of study: To ascertain what out-of-school activities C&YP currently engage in and to determine the facilitators and barriers to participatio
Integration of APs- using the critical incident technique
No full textIt is unquestioned that the assistant practitioner (AP) is a valuable member of the healthcare team; however, some APs have reported challenges in being accepted into their roles. Using a critical incident technique, a purposive sample of 5 assistant practitioners took part in a study, which explored their experiences of working within a multidisciplinary team. More specifically, the objectives of the study were to identify examples of good practice and also to uncover those areas that could be improved. Four key themes emerged from the data: Being acknowledged; professional put-downs; role ambiguity; expectation boundaries. Despite being small-scale, the study concluded that the integration of the AP role is fraught with challenge. The study also concluded that the critical incident technique is a valuable method when undertaking research in this area
Supervised wavelet method to predict patient survival from gene expression data.
No full textIn microarray studies, the number of samples is relatively small compared to the number of genes per sample. An important aspect of microarray studies is the prediction of patient survival based on their gene expression profile. This naturally calls for the use of a dimension reduction procedure together with the survival prediction model. In this study, a new method based on combining wavelet approximation coefficients and Cox regression was presented. The proposed method was compared with supervised principal component and supervised partial least squares methods. The different fitted Cox models based on supervised wavelet approximation coefficients, the top number of supervised principal components, and partial least squares components were applied to the data. The results showed that the prediction performance of the Cox model based on supervised wavelet feature extraction was superior to the supervised principal components and partial least squares components. The results suggested the possibility of developing new tools based on wavelets for the dimensionally reduction of microarray data sets in the context of survival analysis
Pulmonary Delivery of Proteins Using Nanocomposite Microcarriers.
No full textIn this study, Taguchi design was used to determine optimal parameters for the preparation of bovine serum albumin (BSA)-loaded nanoparticles (NPs) using a biodegradable polymer poly(glycerol adipate-co-ω-pentadecalactone) (PGA-co-PDL). NPs were prepared, using BSA as a model protein, by the double emulsion evaporation process followed by spray-drying from leucine to form nanocomposite microparticles (NCMPs). The effect of various parameters on NP size and BSA loading were investigated and dendritic cell (DC) uptake and toxicity. NCMPs were examined for their morphology, yield, aerosolisation, in vitro release behaviour and BSA structure. NP size was mainly affected by the polymer mass used and a small particle size ≤500 nm was achieved. High BSA (43.67 ± 2.3 μg/mg) loading was influenced by BSA concentration. The spray-drying process produced NCMPs (50% yield) with a porous corrugated surface, aerodynamic diameter 1.46 ± 141 μm, fine particle dose 45.0 ± 4.7 μg and fine particle fraction 78.57 ± 0.1%, and a cumulative BSA release of 38.77 ± 3.0% after 48 h. The primary and secondary structures were maintained as shown by sodium dodecyl sulphate poly (acrylamide) gel electrophoresis and circular dichroism. Effective uptake of NPs was seen in DCs with >85% cell viability at 5 mg/mL concentration after 4 h. These results indicate the optimal process parameters for the preparation of protein-loaded PGA-co-PDL NCMPs suitable for inhalation. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci
Galaxy And Mass Assembly (GAMA): growing up in a bad neighbourhood - how do low-mass galaxies become passive?
No full textBoth theoretical predictions and observations of the very nearby Universe suggest that low-mass galaxies (log[M/M]<9.5) are likely to remain star-forming unless they are affected by their local environment. To test this premise, we compare and contrast the local environment of both passive and star-forming galaxies as a function of stellar mass, using the Galaxy and Mass Assembly survey. We find that passive fractions are higher in both interacting pair and group galaxies than the field at all stellar masses, and that this effect is most apparent in the lowest mass galaxies. We also find that essentially all passive log[M/M]<8.5 galaxies are found in pair/group environments, suggesting that local interactions with a more massive neighbour cause them to cease forming new stars. We find that the effects of immediate environment (local galaxy-galaxy interactions) in forming passive systems increases with decreasing stellar mass, and highlight that this is potentially due to increasing interaction timescales giving sufficient time for the galaxy to become passive via starvation. We then present a simplistic model to test this premise, and show that given our speculative assumptions, it is consistent with our observed results
Detection of pathogenic bacteria in aqueous media: Assessing the potential of real-time electromagnetic wave sensing
No full textThis paper reports on the capabilities of a novel electromagnetic wave sensing method to detect and identify the presence of various pathogenic bacteria in aqueous media. In particular, the change in the electromagnetic wave signal in microwave frequency range is used as an indicator of bacteria presence. The assessment was conducted by recording reflected signal spectra when the sensor was in contact with deionised water, Escherichia coli, sterile nutrient broth and Pseudomonas aeruginosa solutions. The distinct feature of the proposed system is that the detection is performed in real time, without the need for additional sample processing or chemicals. This bacteria detection method would be of benefit in a broad range of applications, ranging from water quality monitoring in wastewater treatment facilities to safety assurance in healthcare and food industry
Innovation and its Drivers in SMEs
No full textThe paper reviews the different approaches around innovation and seeks to examine the prevalent practices and drivers for change in businesses with less than 250 employees, which are more commonly known as Small and Medium- Sized Enterprises (SMEs). It is evident from previous discourse that innovation is important for business survival yet current discourse is also fragmented and wide-ranging with little consensus on which approach delivers success. While innovation is important the catalyst for change and for innovative measures to be applied seems to emanate from the entrepreneur. Thus this paper posits there is a vital role and importance that the individual entrepreneur plays as a driver of innovation in SMEs
Climate Change and Future Long Term Trends of Rainfall at North-eastern Part of Iraq
No full textIraq is facing water shortage problem despite the presence of the Tigris and Euphrates Rivers. In this research, long rainfall trends up to the year 2099 were studied in Sulaimani city northeast Iraq to give an idea about future prospects. The medium high (A2) and medium low B2 scenarios have been used for purpose of this study as they are more likely than others scenarios, that beside the fact that no climate modeling canter has performed GCM (global climate model) simulations for more than a few emissions scenarios (HadCM3 has only these two scenarios) otherwise pattern scaling can be used for generating different scenarios which entail a huge uncertainty. The results indicate that the average annual rainfall shows a significant downward trend for both A2 and B2 scenarios. In addition, winter projects increase/decrease in the daily rainfall statistics of wet days, the spring season show very slight drop and no change for both scenarios. However, both summer and autumn shows a significant reduction in maximum rainfall value especially in 2080s while the other statistics remain nearly the same. The extremes events are to decrease slightly in 2080s with highest decrease associated with A2 scenario. This is due to the fact that rainfall under scenario A2 is more significant than under scenario B2. The return period of a certain rainfall will increase in the future when a present storm of 20 year could occur once every 43 year in the 2080s. An increase in the frequency of extreme rainfall depends on several factors such as the return period, season of the year, the period considered as well as the emission scenario used
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