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A Smart Framework for Predicting the Onset of Nocturnal Enuresis (PrONE) in Children and Young People
Bed wetting during normal sleep in children and young people has a significant impact on the child and their parents. The condition is known as nocturnal enuresis and its underlying cause has been subject to different explanatory factors that include, neurological, urological, sleep, genetic and psychosocial influences. Several clinical and technological interventions for managing nocturnal enuresis exist that include the clinician’s opinions, pharmacology interventions, and alarm systems. However, most have failed to produce any convincing results; clinical information is often subjective and often inaccurate, the use of desmopression and tricyclic antidepressants only report between 20% and 40% success, and alarms only a 50% success fate. This paper posits an alternative research idea concerned with the early detection of impending involuntary bladder release. The proposed framework is a measurement and prediction system that processes moisture and bladder volume data from sensors fitted into undergarments that are used by patients suffering with nocturnal enuresis. The proposed framework represents a level of sophistication and accuracy in nocturnal enuresis treatment not previously considered
'The Orchestra of Memory': Music, Sound and Silence in Dermot Healy's 'A Goat's Song'
An analysis of the role of music, sound and silence in an influential modern Irish nove
Two contemporaneous mitogenomes from terminal Pleistocene burials in eastern Beringia
Pleistocene residential sites with multiple contemporaneous human burials are extremely rare in the Americas. We report mitochondrial genomic variation in the first multiple mitochondrial genomes from a single prehistoric population: two infant burials (USR1 and USR2) from a common interment at the Upward Sun River Site in central Alaska dating to ~11,500 calendar years before present (cal B.P.). Using a targeted capture method and next-generation sequencing we determined that the USR1 infant possessed variants that define mitochondrial lineage C1b, while the USR2 genome falls at the root of lineage B2, allowing us to refine younger coalescence age estimates for these two clades. C1b and B2 are rare to absent in modern populations of Northern North America. Documentation of these lineages at this location in the Late Pleistocene provides evidence for the extent of mitochondrial diversity in early Beringian populations, which supports the expectations of the Beringian Standstill Model
On the Progenitors of Local Group Novae. II. The Red Giant Nova Rate of M31
In our preceding paper, Liverpool Telescope data of M31 novae in eruption were used to facilitate a search for their progenitor systems within archival Hubble Space Telescope (HST) data, with the aim of detecting systems with red giant secondaries (RG-novae) or luminous accretion disks. From an input catalog of 38 spectroscopically confirmed novae with archival quiescent observations, likely progenitors were recovered for eleven systems. Here we present the results of the subsequent statistical analysis of the original survey, including possible biases associated with the survey and the M31 nova population in general. As part of this analysis we examine the distribution of optical decline times (t(2)) of M31 novae, how the likely bulge and disk nova distributions compare, and how the M31 t(2) distribution compares to that of the Milky Way. Using a detailed Monte Carlo simulation, we determine that 30 (+13/-10) percent of all M31 nova eruptions can be attributed to RG-nova systems, and at the 99 percent confidence level, >10 percent of all M31 novae are RG-novae. This is the first estimate of a RG-nova rate of an entire galaxy. Our results also imply that RG-novae in M31 are more likely to be associated with the M31 disk population than the bulge, indeed the results are consistent with all RG-novae residing in the disk. If this result is confirmed in other galaxies, it suggests any Type Ia supernovae that originate from RG-nova systems are more likely to be associated with younger populations, and may be rare in old stellar populations, such as early-type galaxies
Can a blended learning approach enhance students transition into higher education? A study to explore perception , engagement and progression.
This paper is concerned with one programme‟s approach when using blended learning activities to support student transition into an English university. Its intention was to capture students‟ attention and curiosity whilst setting patterns for learning and study. The approach combined face-to-face sessions with on-line learning tasks. Research findings support the progress of students in regard to the level of attainment throughout the weekly tasks, although the students were initially challenged by the intensity of the use of ICT applications to support their learning. In conclusion this learning approach was found to be an effective method to support students during the initial weeks at university
Pan-Chromatic observations of the Recurrent Nova LMC 2009a (LMC 1971b)
Nova LMC 2009a is confirmed as a Recurrent Nova (RN) from positional coincidence with nova LMC 1971b. The observational data set is one of the most comprehensive for any Galactic or extragalactic RN: optical and near-IR photometry from outburst until over 6 years later; optical spectra for the first 6 months, and Swift satellite Ultraviolet and X-ray observations from 9 days to almost 1 year post-outburst. We find and expansion velocities between 1000 and 4000 km s. Coronal line emission before day 9 indicates shocks in the ejecta. Strengthening of He II 4686 preceded the emergence of the Super-Soft Source (SSS) in X-rays at days, which was initially very variable. Periodic modulations, days, most probably orbital in nature, were evident in the UV and optical from day 43. Subsequently, the SSS shows an oscillation with the same period but with a delay of 0.28P. The progenitor system has been identified; the secondary is most likely a sub-giant feeding a luminous accretion disk. Properties of the SSS infer a white dwarf (WD) mass . If the accretion occurs at constant rate, yr is needed, consistent with nova models for an inter-eruption interval of 38 years, low outburst amplitude, progenitor position in the color-magnitude diagram, and spectral energy distribution at quiescence. We note striking similarities between LMC 2009a and the Galactic nova KT Eri, suggesting that KT Eri is a candidate RN
Urinary C-peptide measurement as a marker of nutritional status in macaques.
Studies of the nutritional status of wild animals are important in a wide range of research areas such as ecology, behavioural ecology and reproductive biology. However, they have so far been strongly limited by the indirect nature of the available non-invasive tools for the measurement of individual energetic status. The measurement of urinary C-peptide (UCP), which in humans and great apes shows a close link to individual nutritional status, may be a more direct, non-invasive tool for such studies in other primates as well and possibly even in non-primate mammals. Here, we test the suitability of UCPs as markers of nutritional status in non-hominid primates, investigating relationships between UCPs and body-mass-index (BMI), skinfold fatness, and plasma C-peptide levels in captive and free-ranging macaques. We also conducted a food reduction experiment, with daily monitoring of body weight and UCP levels. UCP levels showed significant positive correlations with BMI and skinfold fatness in both captive and free-ranging animals and with plasma C-peptide levels in captive ones. In the feeding experiment, UCP levels were positively correlated with changes in body mass and were significantly lower during food reduction than during re-feeding and the pre-experimental control condition. We conclude that UCPs may be used as reliable biomarkers of body condition and nutritional status in studies of free-ranging catarrhines. Our results open exciting opportunities for energetic studies on free-ranging primates and possibly also other mammals
Edward Carter Preston's Figurehead of Admiral Nelson
The author examines the Modernist sculptor Edward Carter Preston’s carved ship figurehead of Admiral Lord Horatio Nelson (1938). Commissioned for HMS Nelson, a Royal Navy Cadet Training Ship, this representational figurehead was made by laminating together layers of teak rather than by carving into a solid block of wood. The author argues that this was an innovative solution to technical difficulties and indicates an earlier precedent in the sculptor’s oeuvre for this technique when he constructed satirical sculptures out of laminated plywood during the First World War during a time of austerity
Performance comparison of two four-level five-phase open-end winding drives
Two four-level five-phase open-end winding drives are analysed in this paper, and their performances compared. The first topology consists of two two-level voltage source inverters (VSI) supplying a five-phase machine with open-end windings (OeW). The second topology comprises one three-level and one two-level VSI to supply the five-phase OeW machine. In both cases, two VSIs are supplied from isolated dc-sources, with voltages in a ratio 21. As a consequence, the output phase-voltage waveforms are equivalent to those produced by a four-level five-phase VSI. The paper shows that the considered topologies exhibit significantly different operating characteristics