Jurnal Wiyata Penelitian Sains dan Kesehatan
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THE RELATIONSHIP OF PROVIDING EDUCATION ON THE USE OF SELF-MEDICATION DRUGS (Pain, Flu, Faver, Cough) ON THE LEVEL OF KNOWLEDGE OF VISITORS TO ANUGERAH BLUTO MEDIKA PHARMACY IN THE BLUTO SUB-DISTRICT AREA IN 2023
No full textEducation is an activity or effort to deliver health messages to the community, groups, or individuals. Self-medication is a largely community-based effort to overcome disease symptoms before seeking help from health workers. This research aims to determine the influence of providing education on the use of self-medication drugs on the level of knowledge of visitors to Anugerah Bluto Medika Pharmacy in the Bluto Sub-District area. Pre-experimental research with a one group pretest-posttest research design was conducted by comparing the patient\u27s self-medication knowledge before and after being given education using leaflets. The sampling technique used was target sampling with inclusion and exclusion criteria. The sample size consisted of 100 respondents. The results showed that the level of knowledge of pharmacy visitors showed good (11%), sufficient (22%), less (67%) after being given counseling showed good (97%), sufficient (1%), less (2%). ). ). The results of the Chi-Square test obtained a significant value of 0.337 > 0.05 which indicates that there is no relationship between the provision of education and the level of knowledge about the use of self-medication
SCREENING OF SECONDARY METABOLITE COMPOUNDS AND YIELD OF WHITE RHIZOME (Alpinia Galanga L.) EXTRACT THROUGH FOUR EXTRACTION METHODS
No full textBackground: Health maintenance can be addressed by the utilization of natural medicines derived from plants called traditional medicine. Traditional medicine can be produced from rhizomes, one of include was the white galangal rhizome. The chemical compounds of white galangal rhizome provide numerous benefits in both culinary and health fields. Objective: to obtain the best yield from the four extraction methods used. The extracts obtained were tested qualitatively using chemical reagents. Method: The method employed was a laboratory experiment utilizing various extraction techniques. The results indicate that the yields from maceration, soxhletation, reflux, and infusion were 11.955%, 20.359%, 15.737%, and 9.416%, respectively. The secondary metabolite compounds found in the white galangal rhizome extract were flavonoids, alkaloids, tannins, terpenoids, and saponins. Conclusions: it can be concluded that the extraction method with the best yield results was the soxhletation method
EFFECT OF CALCIUM FORTIFICATION ON HEALTH
No full textBackground: As a crucial micronutrient needed for numerous actions related to human health, calcium. Lack of calcium will have an effect on metabolism and body systems, so nutritional intervention in the form of calcium fortification is needed.Objective: To analyze the benefits of calcium fortification on improving health status. Methods: Using a literature review with a narrative method by searching Google Scholar and PubMed then extracting information from the relevant articles. Result: Calcium fortification can improve metabolism and body system work. Conclusion: The addition of calcium through the fortification process is proven to improve health
PERCEPTION OF JAMU USAGE AT ROWOBELANG VILLAGE, BATANG DISTRICT
No full textBackground: The use of traditional medicine as herbs increased relatively neither in developing countries nor developed countries. Efficacy of herbs trusted hereditary. People use herbs as treatment therapy and maintain the health of the body. Some herbs mix medicinal chemical materials illegally. Abuse of it can affect public perception about used herbs in Rowobelang Village, Batang District. Method: This research is a descriptive observational study using a questionnaire instrument containing respondents\u27 sociodemographic data and ten statements to measure public perception about using herbs. The public perception profile was measured in three aspects, there were efficacy aspect, accessibility aspect and safety aspect. Data was taken by using purposive sampling. Results: This research uses 320 respondents as the sample who belong to the inclusion criteria. Characteristics of respondents who filled out the questionnaire are 36-45 years old (35%), high school educated (43,8%), female (63,4%), and have a job (66,5%). The highest aspect that had a high percentage was the efficacy aspect, and the lowest was the safety aspect (28,46%).Conclusion: The result indicates the public perception of herbs used in Rowobelang Village is in the good perception category (72,5%)
PENINGKATAN PENGETAHUAN PENATALAKSANAAN DEHIDRASI PADA IBU DENGAN BALITA RIWAYAT DIARE
No full textLatar Belakang: Diare menjadi penyebab kematian balita di dunia. Komplikasi yang terjadi dari diare adalah dehidrasi. Dehidrasi akan memburuk jika kehilangan air dan elektrolit terjadi secara terus menurus dan tidak segera digantikan bisa menyebabkan syok hipovolemia yang dapat membuat gagal organ, hingga kematian. Salah satu upaya untuk menurunkan angka kematian dan kesakitan diare adalah dengan edukasi kesehatan.Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh edukasi penatalaksanaan dehidrasi di rumah terhadap pengetahuan ibu dengan balita riwayat diare. Metode: Metode penelitian ini adalah Quasi Experimental Design dengan bentuk desain penelitian Nonequivalent Control Group Design. Populasi adalah ibu yang mempunyai balita dengan riwayat diare. Sempel yang digunakan 68 responden kelompok eksperimen (booklet dan demonstrasi) dan 68 responden kelompok kontrol. Teknik pengambilan sampel secara purposive. Pengumpulan data menggunakan kuisoner pengetahuan. Analisis data menggunakan Uji Mann Whitney. Hasil: Hasil Uji Mann Whitney diperoleh nilai Ï 0,000 ( Ï < 0,05). Artinya H0 ditolak dan H1 diterima terdapat pengaruh edukasi penatalaksanaan dehidrasi di rumah terhadap pengetahuan ibu. Kesimpulan: Terdapat pengaruh edukasi penatalaksanaan dehidrasi di rumah terhadap pengetahuan ibu
Hubungan Kepatuhan Diet Dan Gaya Hidup Terhadap Kadar Gula Darah Pada Pasien Diabetes Mellitus Type 2
No full textIntroduction: Frequent consumption of foods and drinks containing sugar and unhealthy lifestyles are an emergency problem for type 2 diabetes mellitus patients. In type 2 diabetes mellitus patients, unhealthy lifestyles and irregular diets cause disease complications resulting in frequent deaths. Objective: This study aims to determine the relationship between diet and lifestyle adherence to blood sugar levels in patients with type 2 diabetes mellitus. Method: Correlational research design using a cross-sectional approach. This research was conducted for the period 1 November 2023 - 30 November 2023. The population in this study were patients diagnosed with T2DM at public health centers X and Y, in Kediri City. Sample measurements can use G Power with a power analysis effect size of 0.5, α err prob 0.05, power (0.95), and an increase in sample size of 20% to obtain a sample of 56 respondents. The sample selection technique was purposive sampling based on inclusion criteria, namely that the patient was willing to take part in the research until completion, the patient could read and write, and the patient was diagnosed with T2DM by a doctor at the public health centers X and Y, in Kediri City. The research statistical test used Spearmans Rho. Results: The relationship between diet and blood sugar levels in type 2 diabetes mellitus patients showed that the majority of type 2 diabetes mellitus patients had poor diet patterns and blood sugar levels ≥ 126, namely 64.3%. The results of the analysis of the relationship between diet and blood sugar levels also showed a p-value of 0.001 < 0.05. The relationship between lifestyle and blood sugar levels in T2DM showed that the majority had poor lifestyles and blood sugar levels ≥ 126, namely 67.9%. The results of the analysis of the relationship between lifestyle and blood sugar levels also showed a p-value of 0.000 < 0.05. Conclusion: There is a relationship between diet and lifestyle on blood sugar levels in type 2 diabetes mellitus patients. Suggestion: In T2DM patients, avoid eating foods and snacks that contain high sugar, and high fat, and control portion sizes to manage blood sugar levels. Do regular physical activity, according to your abilities and doctor\u27s recommendations. Walking, cycling, and other sports can be good choices for controlling blood sugar
DIFFERENCES IN OCCUPATIONAL FACTORS AGAINST MUSCULOSKELETAL COMPLAINTS IN WORKERS WITH DIFFERENT TYPES OF VENTILATION
No full textBackground: Transport workers are one of the jobs in the informal sector. There is a tendency that the work of transportation workers does not have a good organizational system so that they do not think about occupational safety and health. Based on the results of a preliminary study, transport workers in market X and shop houses in market X complain of musculoskeletal complaints even though the two markets have different types of ventilation. Objective: analyze whether there are differences in occupational factors on musculoskeletal complaints in transport workers with different types of ventilation. Method: This research is a comparative descriptive study with 35 respondents each carrying laborers from the market with natural and artificial ventilation. The statistical test of the difference used was the Man-Whitney test because the data were not normally distributed. Conclusions: The results of Asymp. Sig. The 2-tailed variable for working period for musculoskeletal complaints is 0.617 while for the physical workload variable for musculoskeletal complaints it is 0.793. There is no difference between years of work and physical workload on musculoskeletal complaints in haul workers who work in the market with different types of ventilatio
THE EFFECTIVENESS OF THE PHARMACY\u27S ROLE IN PROVIDING DRUG INFORMATION ON TELEPHARMACY
No full textBackground: Telepharmacy is a digital technology-based pharmaceutical service that provides telecommunication between patients and related healthcare services. It offers healthcare services such as drug reviews, counseling, and therapeutic communication with patients, as well as online and real-time exchange of prescriptions. Objective: The effectiveness of the pharmacist\u27s role in the delivery of drug information on the use of health apps. Methods: Current descriptive research using purposive sampling technique for data collection from the general public who have used telepharmacy with variable measurement scales in the study referring to the Likert Scale. Results: This study found that 64.8% of respondents had used telepharmacy to obtain medicine or drug information. According to the community, 82.9% stated that the quality of information obtained through telepharmacy was as good as information provided face-to-face by pharmacists. The community also considered that the role of pharmacists in the utilization of telepharmacy is very important and it is hoped that pharmacists can play an active role in providing drug information regularly in the form of leaflets or website links. Conclusion: Telepharmacy is an alternative health service that allows patients to get quick access and convenience in obtaining health services
IDENTIFIKASI SENYAWA FITOKIMIA EKSTRAK ETANOL 70% AKAR GINSENG KUNING (RENNELLIA ELLIPTICA KORTH.) MENGGUNAKAN LC-MS/MS DAN AKTIVITAS AFRODISIAKA SECARA IN SILICO
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Latar belakang: Rennellia elliptica Korth. secara tradisional digunakan sebagai zat afrodisiak. Dilihat dari potensinya, bukti ilmiah ekstrak tumbuhan ini sebagai penghambat phosphodiesterase-5 masih belum dilakukan Tujuan: Penelitian ini bertujuan untuk mengetahui senyawa fitokimia yang terdapat pada ekstrak etanol 70% tanaman rennellia elliptica Korth. menggunakan LC-MS/MS dan aktivitas afrodisiakan secara in silico. Metode: Ekstrak etanol rennellia elliptica Korth. dianalisis menggunakan LC-MS/MS selanjutnya senyawa tersebut digunakan sebagai senyawa ligan dalam penambatan molekuler untuk mengetahui afinitas pengikatan konstituen fitokimia tersebut terhadap protein target phosphodiesterase 5 (PDB ID: 2H42). Hasil: Ditemukan 17 komponen senyawa antara lain golongan terpenoid, fenilpropanoid, antrakuinon dan flavonoid. Berdasarkan studi in silico dari 17 senyawa yang dianalisis dengan LC-MS/MS, Dulxanthone B (∆G=-9,52 kkal/mol) menunjukkan afinitas tertinggi untuk berikatan dengan target protein. Simpulan: Senyawa fitokimia dari rennellia elliptica Korth. dapat berfungsi sebagai terapi tambahan dalam penemuan obat untuk pengobatan yang menghambat phosphodiesterase 5.
Abstract
Background: Rennellia elliptica Korth. is traditionally used as an aphrodisiac substance. Judging from its potential, scientific evidence of this plant extract as a phosphodiesterase-5 inhibitor has yet to be conducted. Objective: . This research aims to determine the phytochemical compounds contained in the 70% ethanol extract of the Rennellia elliptica Korth plant. using LC-MS/MS. Method: The ethanol extract of rennellia elliptica Korth. was analyzed using LC-MS/MS and then the compounds were used as ligand compounds in molecular docking to determine the binding affinity of the phytochemical constituents to the target protein phosphodiesterase 5 (PDB ID: 2H42). Results: 17 compound components were found, including terpenoids, phenylpropanoids, anthraquinones and flavonoids. Based on in silico studies of 17 compounds analyzed by LC-MS/MS, Dulxanthone B (∆G=-9.52 kcal/mol) showed the highest affinity for binding to protein targets.. Conclusions: Phytochemical compounds from Rennellia elliptica Korth. may serve as an adjunct therapy in drug discovery for treatment that inhibits phosphodiesterase 5
Evaluasi Pelatihan Penggunaan Antropometri untuk Meningkatkan Akurasi Pengukuran sebagai Indikator Deteksi Dini Stunting
No full textLatar belakang: Stunting adalah problematika di bidang kesehatan yang penting, memerlukan perhatian dan penanganan sungguh-sungguh. Kejadian stunting berfokus pada balita dan anak-anak. Stunting ditandai dengan pertumbuhan yang lambat, kekurangan asupan gizi yang dibutuhkan oleh tubuh sejak dalam kandungan. Untuk mendeteksi stunting pada balita, upaya hal yang dapat dilakukan dengan pemantauan pertumbuhan, diantaranya pengukuran tinggi badan dan masa tubuh. Pengukuran tinggi badan pada balita dilakukan dengan menggunakan metode Antropometri, dengan menggunakan alat ukur infantometer atau microtoice. Operasionalisasi kedua alat tersebut terkategori sederhana, namun diperlukan keterampilan dan ketelitian dalam menggunakannya. Tujuan: Pada implementasi penggunaan infantometer dan microtoice masih ditemukan ketidaktepatan pengukuran. Hal ini akan berpengaruh pada keakurasian hasil pengukuran yang diperoleh. Metode: Penelitian ini menggunakan metode eksperimen semu (quasi eksperimental design) dengan rancangan non-randomized pretes-postes design dan strategi unjuk kerja. Penelitian dilakukan dengan empat tahapan penelitian. Hasil: Pada tahapan ke tiga dan keempat diperoleh hasil bahwa keterampilan proses kader Posyandu dalam menggunaan alat sudah terdapat peningkatan, terlihat dari peningkatan nilai posttes. Penilaian dilakukan dengan menggunakan Lembar Pengamatan Keterampilan Proses, dimana setiap kader diminta untuk melakukan unjuk kerja operasionalisasi alat dengan benar. Simpulan: Berdasarkan hasil observasi, tes, monitoring, dan evaluasi diperoleh hasil bahwa kader Posyandu antusias mengikuti pelatihan yang diberikan dan skills penggunaan alat semakin baik dan hasil pengukuran yang diperoleh lebih akurat