92516 research outputs found
Sort by
Assessing the combined effect of gamma radiation and sulfate-reducing bacteria on copper corrosion for deep nuclear waste storage
No full textEffects of manual therapy on oral opening, swallow function and upper quarter mobility in Chilean survivors of head and neck cancer: a study protocol for a controlled, randomised study (MAnual ThErapy for Oral Opening (MATEO) study)
No full textIntroduction: Head and neck cancer (HNC) accounts for over 4% of global cancer incidence, yet the oncological treatment induces several sequelae such as oral dysfunction, cervical and shoulder impairments or pain that are not well addressed. Thus, survivors of HNC (sHNC) perceive a decrease in their quality of life (QoL). This study protocol aims to investigate the effects of manual therapy (MT) to determine the effectiveness and safety on oral opening, swallow function and upper quarter mobility, cervical muscle strength, pain, functionality and QoL of sHNC.
Methods and analysis: A randomised controlled trial will include 70 sHNC over 18 years of age and will be divided into two groups. Intervention will last for 6 weeks with a total of 18 sessions, including MT targeting mastication and head and neck muscles. The control group will receive motor control exercises. The main outcomes will be oral opening and swallow function. An intention-to-treat analysis will be performed to evaluate the effectiveness of the intervention, which will be further determined with the calculation of effect sizes expressed in Cohen's d.
Ethics and dissemination: The study was approved by the Ethics Committee of the Universidad de La Frontera (File 001_24) according to the Helsinki Declaration for Biomedical Research. All participants will provide informed consent. Study results will be published in open access peer-reviewed journals and may be shared at relevant meetings and research meetings.Universidad de La Frontera (DIM23-0023
Analysis of double work among primary school teachers in Latin America
No full textManuel Ángel González-Berruga – Universidad Antonio de Nebrija - 0000-0001-7656-680XRecepción: 25.11.2025 | Aceptado: 01.12.2025Correspondencia a través de ORCID: Manuel Ángel González Berruga - 0000-0001-7656-680XEstudio de investigación sobre calidad de la enseñanza desarrollado por CE-Ed Grupo Investigación en Calidad y Equidad en Educación, Universidad Antonio de NebrijaÁrea o categoría del conocimiento: EducaciónEl presente artículo analiza una realidad que influye en el desarrollo profesional de los docentes en América Latina como es la tenencia de otro trabajo remunerado. El análisis se realiza a partir de los datos del ERCE 2019. Se analizan los datos de los docentes de educación básica de los 16 países participantes: Argentina, Brasil, Colombia, Costa Rica, Cuba, Ecuador, El Salvador, Guatemala, Honduras, México, Nicaragua, Panamá, Paraguay, Perú, República Dominicana y Uruguay. La muestra la componen 3998 docentes de 3º curso y 5527 de 6º curso. Se analiza la influencia de variables relacionas con el sexo, la edad, los años trabajados, el tipo de contrato y la formación utilizando una regresión logística binomial y se utilizan estadísticos descriptivos para visualizar las diferencias entre países. Se utilizan la t de student para analizar diferencias significativas con relación a la formación docentes, desarrollo docente, tiempo dedicado a la escuela, al trabajo con estudiantes y a la satisfacción docente. Los datos arrojan luces y sombras que señala la necesidad de seguir investigando en profundidad y de manera contextualizada. Emerge un perfil de docente con doble jornada insatisfecho con su trabajo, que dedica poco tiempo al desarrollo docente, pero que desarrolla práctica de enseñanza de calidad con los estudiantes.Abstract: The professional development of teachers in Latin America is influenced by the fact that they hold other paid jobs. The analysis is based on data from the 2019 ERCE. Primary school teacher data from the 16 participating countries were analyzed: Argentina, Brazil, Colombia, Costa Rica, Cuba, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, the Dominican Republic and Uruguay. The sample consists of 3,998 third-year and 5,527 sixth-year teachers. Binomial logistic regression is used to analyze the influence of variables related to gender, age, years of service, type of contract and training, and descriptive statistics are used to visualize the differences between countries. A Student's t-test was used to analyze significant differences relating to teacher training, development, time spent at school, working with students, and satisfaction among teachers. The data reveal both positive and negative aspects, highlighting the need for further in-depth, contextualized research. The profile that emerges is that of a double-shift teacher who is dissatisfied with their work and devotes little time to their own development yet provides quality teaching practice to students.Universidad Antonio de Nebrij
The Role of Mobile Applications in Enhancing the Health-Related Quality of Life of Children with Cancer: A Systematic Review and Meta-Analysis
No full textBackground/Objectives: Childhood cancer, although relatively rare, has a profound impact
on the quality of life of affected children and their families. Technological advances have
facilitated the development of mobile applications (apps) aimed at enhancing symptom
monitoring and improving communication with healthcare teams. This systematic review
aimed to analyse the effect of mobile applications on the health of children with cancer,
with a specific focus on health-related quality of life (HRQoL). Methods: A systematic
review was conducted in accordance with PRISMA 2020 guidelines. Searches were performed in PubMed (Medline), CINAHL, Cochrane and Scopus databases using MeSH
terms such as Smartphone, Mobile Applications, Child Health, Neoplasms, and Digital
Health, with no date restrictions, and including studies published in English, Spanish or
Portuguese. We included original research studies that examined the use of mobile apps in
paediatric oncology patients. The search was completed in January 2025. Results: Of the
324 records initially identified, 14 studies (mainly pilot studies, early-phase clinical trials,
and observational designs) met the inclusion criteria. Interventions commonly focused on
symptom tracking (pain, nausea, fatigue), promoting treatment adherence, and delivering
educational content. Several studies reported high user acceptance and a potential positive
impact on HRQoL, particularly when gamification strategies were incorporated to sustain
children’s engagement. Conclusions: Despite the preliminary nature and small sample
sizes of most studies, mobile applications appear to be effective in supporting symptom
management, communication, and health education in paediatric oncology. Their use may
contribute to improvements in HRQoL. Further high-quality research involving younger
children and diverse socio-cultural contexts is required to confirm their effectiveness
Global Challenges: Sustainable Recommendations and Practices in the European Business Environment
No full textEl cambio climático, la pobreza y las crisis económicas representan desafíos globales que la ONU aborda mediante los Objetivos de Desarrollo Sostenible (ODS). En este contexto las empresas europeas mantienen un gran compromiso con el logro de estos mismos, siendo líderes en normativas sostenibles, por lo que su actuación es clave para generar impacto y participación global. Empleando una revisión de la literatura actualizada ofrecemos una metodología interdisciplinar que mejora la competitividad y sostenibilidad empresarial integrando innovación, estrategias empresariales e internacionalización.Climate change, poverty, and economic crises represent global challenges that the UN addresses through its Sustainable Development Goals (SDGs). In this context, European companies maintain a strong commitment to achieving these goals and are leaders in sustainable regulations. Therefore, their performance is key to generating impact and achieving global participation. Using an updated review of the literature, we offer an interdisciplinary methodology that improves business competitiveness and sustainability by integrating innovation, business strategies, and internationalization
On the Enhanced p‐Type Performance of Back‐Gated WS2 Devices
No full textIn this work, a scalable technique is presented for the direct growth of tungsten disulfide (WS2) utilized in back-gated field-effect transistors (FETs), demonstrating robust and persistent p-type behavior across diverse conditions. Notably, this p-type behavior is consistently observed regardless of the metal contacts, semiconductor thickness, or ambient conditions, and remains stable even after high-vacuum and high-temperature annealing. Electrical characterization reveals negligible Fermi-level pinning at the conduction band edge, with minimal Schottky barrier heights for hole carriers below 180 mV and a well-defined thermionic transport regime. The devices exhibit field-effect mobilities with a clear back-gate dependence, reaching values up to 0.1 cm2V−1s−1. Temperature-dependent transport analysis indicates that charge carrier mobility is predominantly limited by impurity scattering and Coulomb interactions. First-principles simulations corroborate that the persistent p-type behavior could be driven by the presence of tungsten vacancies or WO3 oxide species. This study highlights the potential of WS2 for scalable integration into advanced p-type electronic devices and provides critical insights into the intrinsic mechanisms governing its charge transport properties.This research was partially funded by: The C-ING-357-UGR23 project, supported by Consejería de Universidad, Investigación e Innovación and by ERDF Andalusia Program 2021-2027, and the Spanish MICIU/AEI/10.13039/501100011033 projects PID2023-152467OA-I00, PID2021-128547OB-I00, and PLEC2022-009381, with backing from the ERDF/EU and European Union NextGeneration EU/PRTR, respectively. Device fabrication was carried out as part of the European Union Horizon 2020 project ASCENT+, under Grant Agreement no. 871130. The authors also acknowledged the support of Science Foundation Ireland (SFI), through the AMBER Research Centre (SFI-12/RC/2278_P2), as well as the Irish Research Council (IRC) for the EPSPG/2023/1772 project. The SFI/HEA Irish Centre for High-End Computing (ICHEC) is thanked for the provision of computational facilities and support for the DFT simulations. M.C. acknowledged the financial support from the CONCEPT-2D MSCA project (Grant Agreement No. 101062995). The +QCHIP TSI-069100-2023-0003, HORIZON-JU-GH-EDCTP3-2023-01 (EPOCA Grant 101145795) and HORIZON-JU-Chips-2023-RIA-CPL-2 (FAMES ID 101182279) projects were also acknowledged for their financial support
Is Cardiopulmonary Fitness Related to Attention, Concentration, and Academic Performance in Different Subjects in Schoolchildren?
No full textBackground: The perceived importance of physical practice and its contribution to students’ academic success have evolved considerably throughout the history of the modern
educational system. Aim: The purpose of this study was to understand the relationship
between physical fitness (measured as VO2max) and cognitive abilities (attention and
concentration) and academic performance in different subjects: sciences, letters, language,
arts, and physical education. Method: Fifty Spanish male students who participated in
extracurricular sports activities (mean age (SD): 11.59 ± 1.30; range: 9–15 years) were
included in the analysis. The 6 min walk test was used to assess physical fitness (6MWT),
while for selective attention and concentration, the students completed the D2 test, which is
usually considered to analyse the visual ability to select the most relevant stimulus of an exercise and ignore precisely the most irrelevant stimuli. Results: Correlation the individual
contribution analyses revealed no significant associations between VO2max and academic
performance in sciences (r = 0.04, p = 0.77), humanities (r = 0.00, p = 0.98), language (r = 0.03,
p = 0.83), or arts (r = 0.04, p = 0.76). Similarly, no relationship was found between VO2max
and overall academic performance (r = 0.10, p = 0.46), or cognitive abilities. However, a
small positive correlation was observed between VO2max and physical education scores.
Conclusions: Physical fitness showed no significant association with cognitive abilities or
academic performance in most subjects, although a small positive correlation with physical
education scores was observed. These findings emphasise the importance of promoting
physical activity for its health and physical benefits. However, future research should
explore broader cognitive outcomes and include more diverse and representative samples
Beyond antiparasitic activity: elucidating the antibacterial potency of pyrvinium pamoate
No full textAntimicrobial resistance represents a critical global health threat, demanding innovative therapeutic strategies. In this study, we investigate the repurposing
potential of pyrvinium pamoate (PP)—a long-established anthelmintic agent—for
antibacterial applications. Comprehensive in vitro analyses revealed that while gram-negative bacteria exhibited inherent resistance due to limited drug uptake, gram-positive
pathogens, particularly within the orders Actinomycetales and Bacillales, were markedly
susceptible at low micromolar concentrations. Enhanced antibacterial efficacy was
observed when PP was combined with outer membrane-permeabilizing agents, such
as the peptide D11 or pentamidine, which facilitated increased intracellular accumulation. Additionally, the role of efflux pump activity was explored; its inhibition in
Staphylococcus aureus resulted in significant drug retention and a concomitant reduction
in minimum inhibitory concentrations, while disruption of the proton motive force
attenuated uptake. The compound demonstrated bactericidal effects against S. aureus
and a bacteriostatic profile against Pseudomonas aeruginosa when sensitized with
outer membrane permeabilizing agents. Furthermore, synergistic studies with several
antibiotics revealed the potential of PP as a valuable addition to the antimicrobial arsenal
against multidrug-resistant pathogens. These findings motivate further mechanistic
studies and clinical evaluation of PP in antimicrobial therapy. PP shows promise as
a repurposed antibacterial agent, particularly against gram-positive pathogens, with
enhanced activity against gram-negative pathogens when combined with membranepermeabilizing agents or in the presence of efflux pump inhibitors.Instituto de Salud Carlos III (CP21/00113; FI23/00036)Ministerio de Ciencia e Innovación (PID2021-127109OB-I00)Andalusian Board | Consejería de Salud y
Consumo, Junta de Andalucía (CSC) - (PI-0220-2024)Instituto de Investigación Biosanitaria de Granada (MP_ P03_2024
Systematic meta-review on migrant healthcare access: Language barriers and the role of translation
No full textA key challenge migrants face is communication, particularly when they move to countries whose local language they do not speak. Language barriers create significant obstacles in accessing essential services, especially healthcare. These barriers hinder communication between migrants and healthcare providers, resulting in unmet medical needs and adverse health outcomes. In this context, the role of translation and cultural mediation as tools to bridge communication gaps becomes critical. This study conducts a meta-review of existing literature to examine the barriers migrants face in accessing healthcare and explore the role of translation in these circumstances. A sample of 38 literature reviews were selected for analysis. The methodology followed PRISMA guidelines, and qualitative data analysis was performed using NVivo software. Four key themes were identified: access to healthcare, translation, impact on migrant health, and challenges for migrant women. The findings reveal that language, cultural, and economic barriers create difficulties for migrants. Language barriers prevent migrants from understanding medical instructions, navigating healthcare systems, and building trust with providers. Although translation services have demonstrated their potential to mitigate these issues, they remain underutilized. The study concludes by emphasizing the urgent need for systemic measures to promote equitable access to healthcare for migrants. Recommendations include integrating professional translation services into healthcare systems, training providers in cultural competency, and addressing the economic barriers that prevent many migrants from seeking care. By prioritizing these strategies, healthcare systems can better meet the needs of diverse migrant populations and foster more inclusive, equitable care
Emerging trends and challenges in supply chain management and sustainability
No full textThis publication was supported by the R+D+I project PID2021-124396NB-I00, funded by MICIU (Ministry of Science, Innovation and Universities)/AEI/10.13039/501100011033 and by ERDF, EU (European Regional Development Fund) ‘A way of making Europe’. Funding for open access charge: University of Granada / CBUA. We gratefully acknowledge this financial support.The global emphasis on sustainability has been reinforced by international strategies, such as the United Nations' Sustainable Development Goals proposed in the 2030 Agenda. These strategies have prompted a significant transformation in business management practices, leading to the integration of responsible approaches throughout the supply chain processes. This study seeks to evaluate the evolution of research on sustainability within supply chain management and to determine whether it is treated as an inherent component or a separate issue. To achieve this, the study conducts a bibliometric analysis of 3516 articles published in the Web of Science Core Collection database between 2016 and 2024. The analysis reveals a marked increase in scientific output, reflecting the broad involvement of diverse authors, institutions, journals and countries. Six key thematic clusters are identified, highlighting the diversity of the research in this field. This study concludes by suggesting potential directions for future research in supply chain management and sustainability.MICIU (Ministry of Science, Innovation and Universities)/AEI/10.13039/501100011033 and ERDF, EU R+D+I project PID2021-124396NB-I00Funding for open access charge: University of Granada / CBU