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Nudibranchs as Sources of Marine Natural Products with Antitumor Activity: A Comprehensive Review
No full textNudibranchs have garnered increasing interest in biomedical research due to their complex
chemical defense mechanisms, many of which are derived from their diet, including
sponges, cnidarians, tunicates, and algae. Their remarkable ability to sequester dietary
toxins and synthesize secondary metabolites positions them as a promising source of
biologically active compounds with potential therapeutic applications, particularly in
oncology. This study aimed to review and summarize the available literature on the
bioactive potential of nudibranch-derived compounds, focusing mainly on their antitumor
properties. Although research in this area is still limited, recent studies have identified
alkaloids and terpenoids isolated from species such as Dolabella auricularia, Jorunna funebris,
Dendrodoris fumata, and members of the genus Phyllidia. These compounds exhibit notable
cytotoxic activity against human cancer cell lines, including those from colon (HCT-116,
HT-29, SW-480), lung (A549), and breast (MCF7) cancer. These findings suggest that
compounds derived from nudibranchs could serve as scaffolds for the development of
more effective and selective anticancer therapies. In conclusion, nudibranchs represent
a valuable yet underexplored resource for antitumor drug discovery, with significant
potential to contribute to the development of novel cancer treatments
Foro Internacional “Traducción y transmisión cultural: la literatura rusa en el espejo de la traducción” (Ponencias y comunicaciones) 10 – 12 de septiembre de 2024 Granada, España
No full textColección de artículos científicos sobre los resultados del Foro Científico Internacional "Traducción y transmisión cultural: literatura rusa en el espejo de la traducción", Granada, 10 – 12 de septiembre de 2024 / Compiladores y editores: R. Guzmán Tirado, S. V. Ovsyannikova. . Collection of scholarly articles on the results of the International Scientific Forum "Translation and Cultural Transmission: Russian Literature in the Mirror of Translation", Granada, September 10-12, 2024 / Compilers and editors: R. Guzmán Tirado, S. V. Ovsyannikova. Granada: Granada University Press, 2025. 131 p.Grupo de Investigavión "Eslavística, caucasología y tipología lingüística", Universidad de Granad
Services, programs, and local good practices with migrants or applicants for international protection in Granada
No full textEsta publicación ha sido elaborada en el marco del Proyecto Europeo “Global-ANSWER: Global social work and human mobility: comparative studies on local government and good social work practices in the euro-mediterranean region (2020–2025)” y refleja únicamente la opinión de las personas autoras. Este proyecto ha recibido financiación del programa de investigación e innovación Horizonte 2020 de la Unión Europea en virtud del acuerdo de subvención Marie Skłodowska Curie n.º 872209. La Agencia y la Comisión Europea no se hacen responsables del uso que pueda hacerse de la información que contieneIntroducción. La movilidad humana es un fenómeno global que requiere un abordaje multidimensional desde el trabajo social. Facilitar la inclusión social y el bienestar de las personas migrantes, refugiadas o solicitantes de protección internacional a través de iniciativas locales supone un reto para profesionales de la administración pública local y de organizaciones no gubernamentales. Este estudio tiene como objetivos describir los servicios y programas destinados a la atención de estas personas en la ciudad de Granada (Andalucía, España), y conocer las áreas de actuación, colectivos y tipos de iniciativas existentes. De forma complementaria, propone identificar aquellas iniciativas consideradas como buenas prácticas por profesionales y explorar los criterios que emplean para valorarlas de este modo, así como los principales componentes de innovación social que perciben en ellas. La naturaleza dinámica de esta realidad, condicionada por decisiones políticas, presupuestarias y otros factores contextuales, pone de relieve la necesidad de una investigación social aplicada en el ámbito local. Métodos. Se realizó una encuesta online con LimeSurvey y se difundió entre profesionales de servicios sociales del Ayuntamiento y de organizaciones no gubernamentales que trabajan con tales poblaciones en Granada. El trabajo de campo se llevó a cabo entre octubre de 2023 y junio de 2024. El análisis estadístico univariante y bivariante se realizó con SPSS y las preguntas abiertas mediante análisis cualitativo de contenido. Resultados. Las áreas de actuación principales de los servicios y programas identificados son la social, la jurídica, la educativa, la económica, la de salud y la residencial. Los colectivos atendidos más nombrados son mujeres migrantes, personas en situación de irregularidad administrativa, solicitantes de protección internacional, familias migrantes y víctimas de violencia de género. Los servicios y programas más referidos por profesionales del Ayuntamiento son los destinados exclusivamente a personas migrantes o solicitantes de protección internacional, los de infancia y familias, los encargados de tramitar ayudas y las iniciativas para la igualdad de género. Los más señalados por las organizaciones no gubernamentales son los de carácter formativo, de acogida residencial, de inserción laboral, de atención a necesidades básicas y de asesoramiento legal o administrativo. En general, valoran como buenas prácticas casi todas las iniciativas identificadas. Los componentes de innovación social más recurrentes son los que cubren necesidades no atendidas, los que ofrecen soluciones novedosas a problemas estructurales y los que fomentan el empoderamiento. Discusión y conclusiones. Los criterios para considerar servicios y programas como buenas prácticas tienen que ver más con sus fines que con su eficacia, aunque también destacan aquellas iniciativas que contratan a migrantes para atender a migrantes, favoreciendo su inserción laboral y reduciendo así la asimetría de poder en la relación de atención social. Más allá de las limitaciones muestrales, este estudio permitirá el diseño de una guía informativa de servicios y programas en la localidad, de utilidad tanto para personas migrantes o con necesidad de protección internacional como para profesionales del ámbito social.Introduction. Human mobility is a global phenomenon that requires a multidimensional approach from social work. Facilitating the social inclusion and well-being of migrants, refugees, or applicants for international protection through local initiatives is a challenge for professionals working in public administration at the local level and in non-governmental organizations. This study aims to describe the services and programs designed to assist these populations in the city of Granada (Andalusia, Spain), as well as to examine the areas of intervention, target groups, and types of initiatives currently in place. Complementarily, it seeks to identify those initiatives regarded as good practices by professionals and to explore the criteria they use to assess them as such, along with the main components of social innovation they perceive within them. The dynamic nature of this reality—shaped by political, budgetary, and other contextual factors—highlights the need for applied social research at the local level. Methods. An online survey was conducted using LimeSurvey and distributed to social service professionals from the City Council and non-governmental organizations working with these populations in Granada. The fieldwork was carried out between October 2023 and June 2024. Univariate and bivariate statistical analysis was performed using SPSS, and open-ended questions were analyzed using qualitative content analysis. Results. The main areas of action of the services and programs identified are social, legal, educational, economic, health, and residential. The most frequently mentioned groups served are migrant women, people in an irregular administrative situation, applicants for international protection, migrant families, and victims of gender-based violence. The services and programs most frequently cited by City Council professionals are those aimed exclusively at migrants or applicants for international protection, those for children and families, those responsible for processing aid, and initiatives for gender equality. The most frequently exposed by non-governmental organizations are those related to training, residential care, job placement, basic needs, and legal or administrative advice. In general, they rate almost all of the initiatives identified as good practices. The most recurring components of social innovation are that they meet unmet needs, offer innovative solutions to structural problems, and promote empowerment. Discussion and conclusions. The criteria for considering services and programs as good practices have more to do with their purposes than with their effectiveness, although they also highlight initiatives that hire migrants to serve migrants, promoting their job placement and thus reducing the power asymmetry in the social care relationship. Beyond the limitations of the sample, this study will enable the design of an informative guide to services and programs in the locality, which will be useful both for migrants or people in need of international protection and for professionals in the social field.Facultad de Trabajo Social (UGR)Departamento de Trabajo Social y Servicios Sociales (UGR
Development of a comprehensive model for the design of photovoltaic solar public lighting systems in rural and urban areas
No full textThis article presents a model for the optimal design of solar street lighting, considering factors such as street width, required average illuminance, solar irradiance, and luminaire characteristics. The goal is to achieve a sustainable installation that ensures adequate lighting levels. The model optimizes pole distribution, luminaire height, battery capacity, and solar panel power, prioritizing a holistic approach over an individual one. While applicable worldwide, a study conducted in Oman validated its effectiveness, revealing that reducing luminaire power does not always lead to lower overall energy consumption or costs. Its key innovation lies in integrating lighting and renewable energy into a single calculation process—unlike traditional methods, which first design the lighting installation and then calculate the battery and PV module requirements separately
Clinical Practice Guidelines on Normal Labour and Childbirth: A Systematic Review
No full textBackground: Clinical Practice Guidelines (CPGs) are essential for promoting evidence-based maternal and neonatal care, but
inconsistencies in recommendations can be confusing.
Objectives: To analyse the quality and reporting of international CPGs for normal birth and summarise the recommendations.
Search Strategy: Registered on PROSPERO (CRD42021269488), the study identified CPGs on normal birth through systematic
searches in databases like MEDLINE, Cochrane, Scopus and WOS, along with direct outreach to international organisations.
Selection Criteria: CPGs published from 2010 to December 2024 were included, with no language restrictions.
Data Collection and Analysis: The quality and reporting of CPGs were evaluated using the AGREE II and RIGHT tools, and
recommendations were summarised.
Main Results: Of the 25 CPGs analysed, the median AGREE II quality score was 54%, and the median RIGHT reporting score
was 50%. The highest scores were from WHO (2018), CINETS (2013) and the Spanish normal childbirth CPG (2010). Notably,
56% of CPGs had poor reporting, while only 8% were adequately informed. Common recommendations included the presence
of support persons, avoiding routine interventions (e.g., enemas, shaving), encouraging fluid intake, allowing movement during
labour and promoting skin-to-skin contact.
Conclusions: Most CPGs on normal childbirth are outdated and exhibit poor quality and reporting. There is a pressing need for
improvements to ensure valid, consistent and updated recommendations that enhance maternal and neonatal health
The Teacher Training Centres of Andalusia and Social Networks
No full textEsta publicación forma parte del proyecto de I+D+i TED2021-129820B-I00, financiado por MCIN/AEI/10.13039/501100011033, por la Unión Europea NextGeneration EU/PRTR/: "FEDER Una manera de hacer Europa", y por el proyecto PROYEXCEL_00826: " Aprendizaje digital en la formación del profesorado. Análisis de entornos digitales emergentes y la transferencia del aprendizaje al aula", financiado por la Junta de Andalucía. Consejería de Universidades, Investigación e Innovación.
Paula Marcelo-Martínez es beneficiaria de un contrato postdoctoral Juan de la Cierva 2023 (referencia número JDC2023-050398-I), financiada por MCIN/AEI /10.13039/501100011033 y los fondos NextGeneration EU/PRTR de la Unión Europea.Las redes sociales digitales se han convertido en un medio eficaz para difundir información y generar oportunidades de aprendizaje del profesorado y las instituciones de formación del profesorado están haciendo un uso activo de estas nuevas herramientas. El este artículo nos planteamos como objetivo analizar el uso de las redes sociales por los Centros del Profesorado (CEPs) de Andalucía. La investigación analiza las redes y los contenidos compartidos por estos centros, así como la naturaleza de las relaciones digitales entre los CEPs y entre el personal asesor. Se empleó una metodología cualitativa-descriptiva, analizando las redes sociales de los treinta y dos CEPs de Andalucía, incluyendo X, Instagram y Facebook, durante los meses de abril-mayo de 2024. El estudio identificó categorías clave de contenido, como información institucional, ofertas formativas y actividades internas. También empleó un análisis de redes sociales aplicado a las interacciones entre los CEPs y también entre el personal asesor. Los resultados muestran que los CEPs utilizan principalmente las redes sociales para comunicar asuntos institucionales y promover eventos educativos, siendo X la plataforma más utilizada. Además, se evidenció la presencia de espacios digitales de afinidad que fomentan la colaboración entre asesores dentro de su contexto regional. El análisis también revela que, aunque los CEPs interactúan entre sí, estas interacciones suelen ser provinciales, limitando la creación de una red educativa más amplia e integrada. El estudio resalta el potencial de las redes sociales para facilitar comunidades de aprendizaje profesional, pero subraya la necesidad de un enfoque más colaborativo y transprovincial para maximizar su impacto en el desarrollo docente.Digital social networks have become an effective medium for disseminating information and generating learning opportunities. Teacher professional development institutions are actively utilizing these new tools. This study aims to analyze the use of social media by the Centros del Profesorado (CPs) of Andalusia. The research examines the networks and content shared by these centers, as well as the nature of the digital relationships between the CPs and among the advisory staff. A qualitative-descriptive methodology was employed, analyzing the social media presence of the thirty-two CPs in Andalusia, including X, Instagram, and Facebook, during the months of April-May 2024. The study identified key content categories, such as institutional information, training offers, and internal activities. It also applied a social network analysis to examine the interactions between the CPs and between the advisory staff. The results show that CPs primarily use social media to communicate institutional matters and promote educational events, with X being the most widely used platform. Additionally, the presence of digital affinity spaces, such as hashtags and online networks, was observed, which foster collaboration among advisors within their regional context. The analysis also reveals that, although CPs interact with each other, these interactions are often provincial, limiting the creation of a broader and more integrated educational network. The study highlights the potential of social media to facilitate professional learning communities but emphasizes the need for a more collaborative and transprovincial approach to maximize its impact on teacher development.NextGeneration EU/PRTR/Junta de Andalucía PROYEXCEL_00826MCIN/AEI/10.13039/501100011033 TED2021-129820B-I00, JDC2023-050398-
Geochemical Features and Mobility of Trace Elements in Technosols from Historical Mining and Metallurgical Sites, Tatra Mountains, Poland
No full textOre mining and smelting are often related to environmental pollution. This study provides information about the geochemical features of Technosols at historical mining and
metallurgical sites in the Tatra Mountains, southern Poland, evaluating the contents of
potentially toxic trace elements (PTTE) and their behaviours in soils, as well as the influence
of soil properties on PTTE mobility. Thirteen soil profiles were studied in eight abandoned
mining and smelting sites. PTTE concentrations, including rare earth elements (REE), were
measured using ICP-MS and ICP-OES. Selected elements (Cu, Zn, Pb, Cd, As, Sb, Ba, Sr,
Co, Ni, Mn and Cr) were fractionated using the modified European Community Bureau of
Reference (BCR) four-step sequential extraction. Contamination of soils with PTTE was
compared against Polish regulatory limits, which were exceeded for Cu, Zn, Pb, Mo, Hg,
As, Co, Ni and Ba, with concentrations exceeding limits by 16, 18, 34 and 160 times for Cu,
Hg, As and Ba, respectively, in some profiles. Based on geochemical features depending
on parent material properties, the soils examined were divided into three groups. Group I
Technosols (near-neutral soils developed from Fe/Mn-ore and carbonate-bearing mining
waste) were particularly enriched in Co, Ni, Mn and REE. Group II Technosols (acidic
soils developed from polymetallic ore-bearing aluminosilicate mining waste) contained
elevated concentrations of Cu, Zn, Hg, As, Sb, Bi, Co, Ag, Ba, Sr, U and Th; they contained
lower contents of REE than Group I Technosols. Group III Technosols (soils developed in
smelting-affected areas and containing metallurgical waste) were rich in Cu, As, Sb, Ba, Hg,
Co and Ag and contained the lowest REE contents among the studied soils. Sequential
BCR extraction revealed that PTTE mobility varied strongly according to soil group, with
higher mobility of Mn, Cu and Zn in acidic polymetallic ore-derived soils (Group II), while
carbonate-rich soils (Group I) showed mainly immobile forms. Metallurgical slag-derived
soils (Group III) exhibited complex PTTE behaviour controlled by organic matter and
Fe/Mn oxides. Soil properties (pH, carbonates and TOC) seem to control PTTE mobility.National Science Centre, Poland (no. 2021/41/N/ST10/03129
Teoría Lineal
No full textApuntes de Teoría Lineal, Grado en Ingeniería Civil. Edición revisada anualmente.
Class notes on Linear Theory. Bachelor in civil engineering. Revision updated yearly
Implementing STEAM Activities with Biology Teachers in the Context of Ecology
No full textGanime Aydın - Çanakkale Onsekiz Mart University - 0000-0001-6112-5243Gamze Tezcan - Çanakkale Onsekiz Mart University - 0000-0002-7948-5885Fehime Sevil Yalçın - Çanakkale Onsekiz Mart University - 0000-0003-0661-6431Recepción: 20.11.2025 | Aceptado: 05.12.2025Correspondencia a través de ORCID: Ganime Aydın - 0000-0001-6112-5243Financiación: Funded by the Scientific and Technological Research Council of Türkiye [TÜBİTAK]. Project number 123B837 under the TÜBİTAK Science and Society 4005 ProgramÁrea o categoría del conocimiento: STEAM EducationThis study investigates the impact of ecology-based STEAM (Science, Technology, Engineering, Art, and Mathematics) activities on biology teachers’ ecological citizenship, STEAM awareness, and attitudes toward art education. Designed as a convergent parallel mixed-methods study, it involved 26 in-service biology teachers from diverse regions in Türkiye. Quantitative data were collected using three validated instruments: the Ecological Citizenship Scale, the STEM Awareness Scale for Secondary School Teachers, and the Attitude Toward Art Education Scale, applied as pre- and post-tests. Qualitative data was obtained through teachers’ daily reflections, focus group interviews, and lesson plans developed during the training. The results showed significant improvements in teachers' ecological citizenship, STEM awareness, and attitudes toward art education. Teachers appreciated the interdisciplinary nature and classroom applicability of the 26 STEAM activities conducted over six days. While participants expressed high motivation to integrate STEAM practices, some lesson plans revealed insufficient interdisciplinary alignment, particularly in incorporating engineering, mathematics, and technology components. The findings highlight the potential of STEAM-based professional development to support both environmental awareness and pedagogical growth. However, the study also underscores the need for ongoing support in curriculum literacy and integrated instructional design to ensure the effective adoption of STEAM approaches in science education.Çanakkale Onsekiz Mart UniversityProject number 123B837 under the TÜBİTAK Science and Society 4005 Progra
Didáctica, Procesos y Contextos Educativos 3ª ed.
No full textLa asignatura de Didáctica, con diferentes nomenclaturas, pertenece a la rama de las Ciencias Sociales y Jurídicas, inserta en el módulo Organización del espacio escolar, materiales y habilidades docentes, e incluida en la materia Educación. Se hace un recorrido por los aspectos fundamentales de la ciencia de la Didáctica con relación al proceso de enseñanza y aprendizaje, con base experiencial de los elementos curriculares que se deben conocer, a través de la formulación y respuesta de las preguntas clave: ¿qué, cómo y cuándo enseñar? y ¿qué, cómo y cuándo evaluar?, y la manera de programar el ejercicio profesional docente. Se abordan las instrucciones y saberes del correspondiente área de conocimiento desde una perspectiva general y básica en la formación y desarrollo profesional del docente, siendo sus principales destinatarios el alumnado, profesorado y educadores de Educación Infantil, Primaria, Secundaria, Bachillerato, Formación Profesional, Pedagogía, Psicopedagogía, Educación Social y en el ámbito no formal.
Ser un buen docente es saber transmitir, e incluso hasta ser un buen actor o actriz: a veces intérprete, otras figurante, quizá comediante, o animador, aunque siempre responsable de las relaciones y el discurso que aproximan y cimientan el aprendizaje. Para ello, se intenta ser conscientes de las particularidades en la comunicación. La Didáctica ofrece abundantes coincidencias en sus ofertas transversales aplicables a todos los niveles del Sistema Educativo, con el propósito de poder adaptar y acomodar sus esencias a los diversos ecosistemas educativos, tipos de educación y creatividad en los diversos episodios didácticos