Publications scientifiques de l'Université de Reims Champagne-Ardenne
Not a member yet
27404 research outputs found
Sort by
L'inconduite exemplaire
No full textInternational audienceNote sous CE, 3 juillet 2025, no 499082 (inédit au Lebon
Introduction: Jesuit Rhetoric across Space and Time: Local and Global Perspectives
No full textInternational audienc
Aesthetics of the Frontier in Django Unchained (Quentin Tarantino, 2012)
No full textInternational audienc
Type 2 Inflammatory Biomarkers and Lung function Improvement in Patients with Chronic Obstructive Pulmonary Disease (COPD) Receiving Placebo Therapy
No full textInternational audienc
Analyse du développement cérébral précoce par recalage d'IRM longitudinales basée sur un champ de vélocité stationnaire
No full textNational audienc
Effectiveness of protected areas in limiting agricultural encroachment and conserving herbivores in West‐Central African savannahs
No full textInternational audienceThis study examines the long‐term effectiveness of protected areas (PAs) in the savannahs of West and Central Africa in resisting agricultural encroachment and conserving large herbivore populations. Using Landsat imagery (1973–2018) and wildlife census data, we evaluated land‐use and land‐cover change within ten core PAs and their surrounding 60‐km buffer zones, focusing on four focal species: african buffalo, roan antelope, hartebeest and savannah elephant. Results show that core PAs largely retained their natural vegetation, while surrounding landscapes experienced significant agricultural expansion—particularly in unprotected buffer zones. National parks, especially those embedded within connected networks such as the W–Arly–Pendjari complex, demonstrated stronger resistance to land conversion and higher herbivore biomass. However, wildlife population trends did not consistently align with landscape integrity, indicating that factors such as PA size, governance and ecological connectivity critically shape conservation outcomes. We identify three typologies of PAs—underperforming large reserves, integrated transboundary networks and small but well‐managed sites—each requiring distinct strategic approaches. These findings underscore the need for outcome‐focused conservation strategies that go beyond legal designation to address spatial planning, connectivity and local management capacity
L'intervention irrégulière d'un comité ad hoc dans la procédure de promotion interne au corps des professeurs des universités
No full textInternational audienceObservations sous CE, 7 novembre 2025, no 497896 (Lebon T.
Description du lien entre épigénétique et autisme
No full textLes troubles du spectre autistique, appelés plus communément « autisme » regroupent un ensemble de troubles neurodéveloppementaux dont la prévalence ne cesse d’augmenter ces dernières décennies. Il s’agit d’une pathologie multifactorielle résultant à la fois de facteurs génétiques, épigénétiques et environnementaux. Cette thèse a pour objectif de décrire les mécanismes épigénétiques impliqués dans l’autisme en analysant les résultats de différentes études parues dans la littérature scientifique ces dernières années. La connaissance de ces mécanismes pourrait constituer une avancée importante dans la prise en charge de cette pathologie en offrant de nouvelles perspectives thérapeutiques et diagnostiques
Assessing anaerobe detection in routine sputum analyses from cystic fibrosis patients
No full textInternational audiencePulmonary involvement in cystic fibrosis (CF) includes bronchiectasis and chronic airway infection, with nearly half of the airway bacteria being anaerobes. Some anaerobic species, such as Porphyromonas catoniae, have been identified as predictive biomarkers for Pseudomonas aeruginosa colonization, with P. catoniae decreasing as the disease progresses. Although 16S rRNA metagenomics offers a comprehensive view of airway anaerobes, it is not routinely performed in clinical microbiology laboratories. This study aimed to evaluate the ability of routine sputum culture to identify strict anaerobes in people with CF (pwCF) compared to 16S rRNA sequencing, and to assess the impact of sample transport conditions. Sputum from 48 pwCF was analyzed by anaerobic culture and 16S rRNA sequencing. Strict anaerobes were detected in 95.8% of patients by culture and 100% by 16S rRNA sequencing. Culture identified 23 strict anaerobic species (mean 2.6 per sample), while 16S rRNA sequencing revealed nearly 100 species (mean 43 per sample). Importantly, culture isolated key genera such as Veillonella and Prevotella, core members of the CF airway anaerobiome. Transport conditions (aerobic vs anaerobic) did not affect anaerobe detection. These new findings support changes in the processing of CF sputum in the everyday practice of clinical microbiology laboratories and promote the characterization of the culturable anaerobic airway microbiota