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Partially Penetrating Lake-Aquifer Interaction in a Laboratory-scale Tidal Setting
No full textDataset made available per the CC BY 4.0 Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/Freshwater lakes close to the coast are important ecotones with strong functional dependency on ocean forces. Tides are likely to create dynamic lake-groundwater interactions, which have not been previously assessed for partially penetrating lakes. This study investigates tidal lake-groundwater interaction in a laboratory-scale aquifer cross-section with and without the existence of a partially penetrating lake. The experimental observations were reproduced by numerical models to allow for an in-depth evaluation of the experiments beyond those provided by direct measurements
End-of-Life Online Health Education Uptake and Usage by Australian Health Professionals: Urban, Rural and Remote Settings
Full text linkThis work is copyrighted. It may be reproduced in whole or in part for research or training purposes, subject to the inclusion of an acknowledgement of the source. It may not be reproduced for commercial use or sale. Reproduction for purposes other than those indicated above requires written permission from the Flinders University Research Centre for Palliative Care, Death & Dying. Contact [email protected] for permissions.Access to skilled end-of-life care is particularly important for those who live in rural and remote areas in Australia given the high levels of chronic disease and higher mortality rates. However, health professionals in rural and remote areas do not always receive adequate training to provide this care due to lack of accessible education. End-of-Life Essentials (EOLE) is a government funded education project which aims to provide free peer-reviewed online education modules and implementation resources on end-of-life care to health professionals in acute hospitals in Australia. In order to understand the uptake and usage of the EOLE education modules, learners’ geographical locations and module completion data from the first year of the program were analysed according to remoteness category.
This White Paper outlines and explores the results of the retrospective data analysis conducted in June 2018. Data from learners who registered in the first year of the EOLE program was were extracted, and 4224 learners were included for data analysis. Study findings show that there is a good reach of EOLE to health professionals living in remote and very remote areas. As learners from very remote areas showed the highest proportion of module completion, it suggests the potential benefit of this important online education in providing accessible continuing end-of-life care education for health professionals residing in the most remote parts of Australia
Decision-Support Modelling viewed through the lens of Model Complexity
Full text link© Flinders University 2021. Copyright: This work is copyright. Apart from any use permitted under the Copyright Act 1968, no part may be reproduced by any process, nor may any other exclusive rights be exercised, without the permission of Flinders University, GPO Box 2100, Adelaide 5001, South Australia.A report on decision-support for groundwater modelling and management. The authors’ perspectives on decision-support modelling are shown pictorially using a “roadmap”. This is intended to provide modellers with scientifically-based guidance for selection of a level of structural and parameterisation complexity that is appropriate for the decision-support context in which they are working. It may also assist modelling stakeholders to understand how groundwater modelling can best respond to the decision support imperatives that it is meant to serve
Dying, a normal part of life: what learners see as the one thing they could change in the workplace to more appropriately provide end-of-life care
Full text link© Flinders University. This work is copyrighted. It may be reproduced in whole or in part for research or training purposes, subject to the inclusion of an acknowledgement of the source. It may not be reproduced for commercial use or sale. Reproduction for purposes other than those indicated above requires written permission from the Research Centre for Palliative Care, Death & Dying. Contact [email protected] for permissions.End-of-Life Essentials (EOLE) is a government funded project which aims to provide free peer-reviewed online education modules and implementation resources on end-of-life care to health professionals in acute hospitals in Australia. 'Dying, A Normal Part of Life' is an educational module featured in the suite of EOLE modules and includes education around the impact of end of life and dying on health care professionals working in acute hospitals, identifying common patterns of trajectories of dying, and discussing the reasons why dying in acute hospitals is often complex for professionals, patients, and families.
This White Paper outlines and explores the results of the retrospective data analysis conducted for a two year period, 6th May 2017 to 5th May 2019. A total of 2232 learner statements responding to the free text response question posed at the end of the module: "Tomorrow, the one thing I can change to more appropriately provide end-of-life care is…" were extracted from the EOLE learning platform. The results identified the following themes as nominated practice change areas: Patient-centred care; Communication skills; Humanising healthcare; Recognise and talk about dying; Organisational factors
The hydrogeology of the Rocky Hill Region, Northern Territory
Full text linkThis publication is copyright. Other than for the purposes of and subject to the conditions prescribed under the Copyright Act RN 1968, no part of it may in any form or by any means (electronic, mechanical, microcopying, photocopying, recording or otherwise) be reproduced, stored in a retrieval system or transmitted without prior written permission. Enquiries should be addressed to the National Centre for Groundwater Research and Training, at Flinders University.The Rocky Hill area has been identified as a potential future bore field for Alice Springs town water supply, and in 1996 NT Portion 4704 was set aside for that purpose. The area has been the focus of several hydrogeological investigations over the past 50 years, most recently in 1998-2000 (Read and Paul, 2000, 2002). The current report updates the hydrogeological characterisation of this area, based on drilling and sampling of new test production bores within NT Portion 4704, and water level, geochemistry and geophysical surveys carried out within the Rocky Hill region within the last 20 years. This data will be used in a groundwater model which will assess the long-term sustainability of Rocky Hill as a future water supply for Alice Springs. The groundwater model will be the focus of a subsequent report
South Australian Allied Health Rural Generalist Pathway Evaluation: Phase 2 Report
Full text link© 2020 Flinders UniversityIn 2019 the Allied Health Rural Generalist Pathway (AHRGP) was introduced in SA Health Regional Local Health Networks (LHNs) through the provision of Rural Health Workforce Strategy funding from the Government of South Australia. This was one of a range of projects funded by this strategy to improve workforce outcomes and the quality of health service provision in rural and remote areas. The AHRGP is a post graduate training course for AHPs working in rural or remote areas designed to develop rural generalist specialist skills and knowledge. The AHRGP also includes an expectation for trainees to progress service improvement projects that utilise one or more nominated rural generalist service strategies, have dedicated profession specific supervision, and have protected study time at work
An evaluation of the nexus between labour migration, remittances and the wellbeing of migrants and their families in Timor-Leste : Some key findings from a pilot survey conducted in Timor-Leste 2019
Full text link© 2020 Flinders University. All rights reserved.The findings presented here are from a pilot research conducted in Dili, Timor-Leste in the month of April/May 2019. This pilot research was funded by Flinders University. Ethics approval for the same was obtained from Social and Behavioural Research Ethics Committee of Flinders University. The questionnaire used for this pilot was developed in consultation with SEPFOPE (Secretary of State for Vocational Training and Employment Policies) and General Directorate of Statistics (Statistics-TL), Government of Timor-Leste, and the United Nations Development Programme, Timor-Leste. The data were collected by a team of field investigators from Statistics-TL.
The research tool that we developed for the full-fledged project and its pilot study investigates the remittance workers’ experiences as a whole by using a multi-dimensional framework. This framework considers five dimensions of life satisfaction at a household level, namely standard of living, education, health (psychological/ emotional), community vitality and cultural vitality, and three specific dimensions of wellbeing and capability at an individual level, namely economic, knowledge/skills, and health. The pilot survey comprises a blend of objective and subjective questions. A total of 30 (18 males and 12 females) Timorese seasonal workers who worked in Australia during the period 2016-2018 under Australia’s Seasonal Workers Program (SWP) and since returned to Dili, Timor-Leste were surveyed. The findings presented here in Figures 1 through 13 are based on an analysis of individual level data
The genetic and clinical landscape of nanophthalmos and posterior microphthalmos in an Australian cohort
Full text link© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
This author accepted manuscript is made available following 12 month embargo from date of publication (February 2020) in accordance with the publisher’s archiving policyNanophthalmos and posterior microphthalmos are ocular abnormalities in which both eyes are abnormally small, and typically associated with extreme hyperopia. We recruited 40 individuals from 13 kindreds with nanophthalmos or posterior microphthalmos, with 12 probands subjected to exome sequencing. Nine probands (69.2%) were assigned a genetic diagnosis, with variants in MYRF , TMEM98 , MFRP , and PRSS56 . Two of four PRSS56 families harbored the previously described c.1066dupC variant implicated in over half of all reported PRSS56 kindreds, with different surrounding haplotypes in each family suggesting a mutational hotspot. Individuals with a genetic diagnosis had shorter mean axial lengths and higher hyperopia than those without, with recessive forms associated with the most extreme phenotypes. These findings detail the genetic architecture of nanophthalmos and posterior microphthalmos in a cohort of predominantly European ancestry, their relative clinical phenotypes, and highlight the shared genetic architecture of rare and common disorders of refractive error
Jane Austen: The French Connection
Full text linkConcert program for Jane Austen: The French Connection, held at the Barr Smith Library Reading Room on Sunday 17 October 2020.
A concert of French music from Jane Austen's music collection and that of her family. Songs by Paisiello, Devienne, Gretry, Storace and even (possibly) Queen Marie Antoinette, with music for solo harp by Krumpholtz and Dalayrac.
Gillian Dooley (voice), Christine Morphett (harp), Mark Smith (cello).Presented by the Friends of the Adelaide University Library
An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity
Full text link© 2020 by the American Academy of Ophthalmology. This manuscript version is made available under the CC-BY-NC-ND 4.0 license: http://creativecommons.org/licenses/by-nc-nd/4.0/Purpose
To examine the combined effects of common genetic variants associated with intraocular pressure (IOP) on primary open-angle glaucoma (POAG) phenotype using a polygenic risk score (PRS) stratification.
Design
Cross-sectional study.
Participants
For the primary analysis, we examined the glaucoma phenotype of 2154 POAG patients enrolled in the Australian and New Zealand Registry of Advanced Glaucoma, including patients recruited from the United Kingdom. For replication, we examined an independent cohort of 624 early POAG patients.
Methods
Using IOP genome-wide association study summary statistics, we developed a PRS derived solely from IOP-associated variants and stratified POAG patients into 3 risk tiers. The lowest and highest quintiles of the score were set as the low- and high-risk groups, respectively, and the other quintiles were set as the intermediate risk group.
Main Outcome Measures
Clinical glaucoma phenotype including maximum recorded IOP, age at diagnosis, number of family members affected by glaucoma, cup-to-disc ratio, visual field mean deviation, and treatment intensity.
Results
A dose–response relationship was found between the IOP PRS and the maximum recorded IOP, with the high genetic risk group having a higher maximum IOP by 1.7 mmHg (standard deviation [SD], 0.62 mmHg) than the low genetic risk group (P = 0.006). Compared with the low genetic risk group, the high genetic risk group had a younger age of diagnosis by 3.7 years (SD, 1.0 years; P < 0.001), more family members affected by 0.46 members (SD, 0.11 members; P < 0.001), and higher rates of incisional surgery (odds ratio, 1.5; 95% confidence interval, 1.1–2.0; P = 0.007). No statistically significant difference was found in mean deviation. We further replicated the maximum IOP, number of family members affected by glaucoma, and treatment intensity (number of medications) results in the early POAG cohort (P ≤ 0.01).
Conclusions
The IOP PRS was correlated positively with maximum IOP, disease severity, need for surgery, and number of affected family members. Genes acting via IOP-mediated pathways, when considered in aggregate, have clinically important and reproducible implications for glaucoma patients and their close family members