Repository of the Sestre milosrdnice University Hospital Center
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Rak jajnika, jajovoda i potrbušnice: kirurško liječenje
Surgery is the cornerstone of effective management of the ovarian, tubal and peritoneal cancer. In 2014 the International Federation of Gynecology and Obstetrics (FIGO) published a new classification collectively covering cancer of ovary, fallopian tube and peritoneum as well as malignant ovarian germ cell tumors and malignant sex-cord stromal tumors. Comprehensive surgical staging according to the 2014 FIGO classification system plays an important role in management of apparently early stage of ovarian, tubal and peritoneal cancer. Primary debulking (cytoreductive) surgery followed by paclitaxel and platinum based combination chemotherapy is the cornerstone of the advanced-stage disease treatment. In cases of suboptimal primary cytoreduction, interval debulking surgery performed after two to four cycles of chemotherapy based on the clinical judgment of the gynecologic oncologist is second attempt to achieve optimal cytoreduction. Secondary cytoreductive surgery can be considered in patients with platinum-sensitive locally recurrent ovarian cancer. The volume of residual tumor remaining after these surgical approaches is one of the most important independent prognostic factors for survival.Kirurško liječenje je temelj uspješnog liječenja raka jajnika, jajovoda i potrbušnice. Međunarodno federacija ginekologa i opstetričara (FIGO) u 2014. godini objavila je novu klasifi kaciju koja zajedno obuhvaća rak jajnika, jajovoda, potrbušnice, zloćudne tumore zametnih stanica i zloćudne tumore specijalizirane strome jajnika. Kirurško stupnjevanje bolesti prema FIGO 2014 klasifi kaciji je ključno u liječenju raka jajnika, jajovoda i potrbušnice naizgled ranog stadija bolesti. Primarna citoredukcijska kirurgija i dodatno liječenje kemoterapijom je standardni pristup uznapredovaloj bolesti. Prilikom suboptimalne citoredukcije tijekom primarnog kirurškog zahvata “interval debulking surgery” nakon drugog do četvrtog ciklusa kemoterapije, ovisno o procjeni ginekološkog onkologa, drugi je pokušaj postizanja optimalne ciotredukcije. Sekundarna citoredukcijska kirurgija dolazi u obzir kod pacijentica koje su osjetljive na kemoterapiju, a imaju lokalni povrat bolesti. Veličina rezidualnog tumorskog tkiva nakon kirurških zahvata je najznačajniji prognostički čimbenik na koji se može utjecati tijekom liječenja
Acta clinica Croatica: a progress step by step
The journal Acta Clinica Croatica (ACC) was founded in 1962 under the title Anali Bolnice Dr. M. Stojanović. In 1995, the title of the journal was changed into its present form and ever since all papers have been published in English. In 2000, the electronic (online) edition of the ACC was released in addition to the print version. The paper presents development of the journal from 1962 to 2012 based on the analysis of the following SCOPUS citation index parameters: type and number of documents published in the journal; number of citations; and number of domestic and foreign authors. The studied period was analyzed in three time segments: the period from 1995 to 1999, the period from 2000 to 2006 and the period from 2007 to 2012. The same parameters were analyzed in the Web of Science/SCI-Expanded bibliographic and citation index for the 2007-2012 period. The increasing number of documents, authors (both domestic and foreign) and citations demonstrates gradual rise in the quality, visibility and impact of the journal. The fifty years of experience show that a goal, at first very distant and almost unachievable, may be reached by progressing step by step.Časopis Acta Clinica Croatica počeo je izlaziti 1962. godine na hrvatskom jeziku pod nazivom Anali Bolnice Dr. M. Stojanović. Godine 1995. naziv časopisa se mijenja u današnji, a svi radovi se objavljuju na engleskom jeziku. Godine 2000. objavljuje se i mrežna (online) verzija. U radu se prati razvoj časopisa od 1962. do 2012. godine temeljem analize vrste i broja radova, broja citata te broja domaćih i stranih autora u indeksnoj i citatnoj bazi SCOPUS (u tri razdoblja). Isti su parametri analizirani u bazi Web of Science/SCI-Expanded za razdoblje od 2007. do 2012. godine. Uzlazna krivulja rasta broja radova, autora i citata svjedoči o postupnom povećanju kvalitete, vidljivosti i značajnosti časopisa. Pedesetogodišnje iskustvo pokazuje da se korak po korak može stići i do na prvi pogled jako udaljenog ili teže ostvarivog cilja
The Role of a Hospital Library in Scientific Research and Productivity of its Institution - Experience of the "Sestre Milosrdnice" University Hospital Center Medical Library
KBC "Sestre milosrdnice" (KBCSM), jedna od najstarijih i najvećih zdravstvenih ustanova u Republici Hrvatskoj, nastavna je baza sedam fakulteta Sveučilišta u Zagrebu. Uz projekte Ministarstva znanosti, obrazovanja i sporta, u KBCSM provode se međunarodna klinička istraživanja. Djelatnici KBCSM stalno objavljuju veliku količinu radova u znanstvenim časopisima te su autori, koautori i urednici mnogih znanstvenih knjiga. Knjižnica KBCSM organizirana je kao mreža knjižnica na tri lokacije. Podrška Knjižnice znanstvenom radu – produkciji djelatnika KBCSM ostvaruje se kroz stalnu nabavu građe te kroz različite knjižnične usluge, a od lipnja 20 Il. godine posebna se pažnja poklanja poučavanju korisnika. Osim toga, Knjižnica pruža potporu i izdavačkoj djelatnosti kroz rad u uredništvu časopisa čiji je izdavač KBCSM - Acta Clinica Croatica, Libri Oncologici i Alcoholism. Nedovoljno knjižničnih djelatnika otežava proširivanje usluga i načina potpore znanstvenom i istraživačkom radu djelatnika KBCSM. Jačanje uloge Knjižnice KBCSM u znanstvenoj produkciji matične ustanove i doprinosu djelatnika KBCSM afirmaciji znanosti kao društvenoj vrijednosti moguće je ostvariti kroz poučavanje djelatnika KBCSM u evidentiranju znanstvene produkcije kao i u informiranju javnosti o istraživačkim aktivnostima znanstvenika i znanstvenih ustanova. U ostvarivanju ovih ciljeva, uz veći broj knjižničnih djelatnika, potrebna je inovativna suradnja Knjižnice KBCSM s bolničkim i drugim specijalnim i visokoškolskim knjižnicama te Nacionalnom i sveučilišnom knjižnicom u Zagrebu.The "Sestre milosrdnice" University Hospital Center (SMUHC), one of the oldest and largest health facilities in the Republic of Croatia, is a teaching hospital affiliated with seven faculties of the University of Zagreb. Numerous international c1inical research studies have been conducted in the SMUHC in addition to scientific projects that are supported by the Croatian Ministry of Science, Education and Sports. Over the years, hospital staff members have published a large number of papers in scientific journals, and are authors, co-authors or editors of many scientific books. The SMUHC Medical Library operates at three locations of the Hospital. lt supports scientific work and publishing of the hospital staff by continuous acquisition of biomedical books and journals (both foreign and Croatian) and through various library services. Special attention is being given to user education since June 2011. The Library also supports publishing of the three journals published by the SMUHC - Acta Clinica Croatica, Libri Oncologici and Alcoholism. A shortage of library staff does not allow expansion of library services and support to teaching and scientific research staff. The role of SMUHC Medical Library in scientific research and productivity along with the contribution of hospital staff to promotion and affirmation of science as a social value can be strengthened by educating SMUHC medical staff in how to record their scientific data and inform the public about their research activities. To accomplish all this, innovative cooperation of the SMUHC Medical Library with hospital libraries, other special and academic libraries and the Croatian National and University Library is mandatory along with the increased number of hospital librarians
One day clinic'
Prema iskustvu vodećih onkotoških centara u svijetu u Klinici za tumore se preko godinu dana održava jednom tjedno jednodnevna dijagnostika dojke. Pacijentice su obrađene ujutro dijagnostički kada se prvo radi MMG ako je potrebna, zatim punkcija pod kontrotom UZV i MR dojki ako se dobije citotoški pozitivan nalaz te se pacijentica u popodnevnim satima sa svom obradom uputi kirurgu ili onkologu
The value of thyroglobulin as a biomarker for iodine deficiency
Current methods for assessment of iodine intake of a population comprise measurements of urinary iodine concentration (UIC), thyroid volume by ultrasound (US-Tvol) and newborn TSH. Serum or dried blood spot thyroglobulin (DBS-Tg) is a new promising functional iodine status biomarker in children
Natural eye gaze computer interaction for medical oculography diagnosis: Current status and future prospects
With recent technological developments, modern computing systems are becoming more and more powerful. Common computers are capable of calculating more than 50,000 million instructions per second. Currently the biggest obstacle in computer usage is slow communication between the human and the computer. With innovation and development of novel (natural based) sensors capable of capturing positions and natural motion of human body a new, natural, way of interacting with computer is enabled.
This paper gives an overview of eye tracking technology, and presents its application in nature based human-computer interaction (HCI) systems by extending standard controllers, such as the keyboard and the mouse. Novel approaches enable HCI closer to the communication patterns of human beings. In addition, the usage of those concepts in applications for eye diseases and disorders diagnostics and rehabilitation is discussed
Prikaz bolesnice s dubokom venskom trombozom liječene fibrinolizom te perkutanom mehaničkom trombektomijom
MRI zdjelice u ginekološkoj onkologiji
Prikaz odabira sekvenci i moduliranja pregleda kod preoperativnih onkotoikih pacijentica prema organu i suspektnoj patotogiji
Unruptured Giant Intracranial Aneurysm of the Internal Carotid Artery: Late Ocular Symptoms
An unruptured giant intracranial aneurysm of the internal carotid artery may tend to present with late ocular symptoms. This is the case of a 58-year-old female patient with a giant unruptured aneurysm of the right internal carotid artery. The patient presented with exclusively progressive reduction of visual acuity and visual field defects due to the mass effect of the growing aneurysm. The rupture of the aneurysm occurred before planned treatment. Clinical suspicion and timely recognition as well as prompt treatment play an important role in the final outcome of the management of giant unruptured intracerebral aneurysms
Salutogenic approach to promoting cardiovascular health
Koncept salutogeneze – „stvaranja zdravlja“, podrazumijeva kontinuum zbivanja od stanja lošega zdravlja (engl. dis-ease) do potpunoga zdravlja (engl. ease), pri čemu je važnije usmjeriti se na resurse koji će pridonijeti stvaranju i održavanju zdravlja, nego se uobičajeno usredotočiti na zdravstvene rizike i bolesti – salutogeneza vs. patogeneza. Salutogenezom se prospektivno razmatra kako razviti, povećati i poboljšati fizičko, psihičko i socijalno blagostanje. Salutogeneza ovisi o koherenciji između pojedinca i njegove okoline. Osobe s primjerenim općim obrambenim mehanizmima mogu, učenjem kroz iskustva, postupno razviti snažan osjećaj koherencije, što pridonosi zdravlju – naime, veći osjećaj koherencije podrazumijeva bolje zdravlje i kvalitetu života. U razvoju kardiovaskularnih bolesti važnu ulogu imaju emocije, promišljanja i stavovi pojedinca, pridonoseći preuranjenom početku bolesti ili poboljšanju zdravlja. U okviru zdravog stila života, u promicanju kardiovaskularnoga zdravlja, uz salutogeni koncept pozitivne psihologije, treba se usmjeriti i na već dobro poznate čimbenike, osobito zdravu prehranu, redovitu tjelesnu aktivnost, primjerenu uhranjenost, te nepušenje. Stil življenja, povezan s osjećajem koherencije (engl. sense of coherence – SOC), jedan je od odlučujućih čimbenika zdravlja.The concept of salutogenesis -„creating health“ implies a continuum of events from the state of poor health (dis-ease) to total health (ease), where it is more important to focus on the resources that will contribute to the creation and maintenance of health, rather than the usual focus on health risks and diseases – salutogenesis vs. pathogenesis. Salutogenesis prospectively examines how to create, enhance and improve physical, mental, and social well-being. Salutogenesis is dependent on the coherence between the individual and his environment. People with adequate generalized defense mechanisms can, through learning experience, gradually develop a strong sense of coherence (SOC), which contributes to health – a higher SOC implies better health and quality of life. In the development of cardiovascular diseases an individual’s emotions, thoughts and attitudes play an important role, contributing to premature onset of a disease or improvement of health. As part of a healthy lifestyle and promoting cardiovascular health, in addition to the salutogenic concept of positive psychology, attention should also be directed toward already known factors, especially a healthy diet, regular physical activity, appropriate body mass, and not smoking. Lifestyle, associated with SOC, is one of the determining factors of health