Journal for ReAttach Therapy and Developmental Diversities (JRTDD)
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Temporomandibular Joint Disorders in Postmenopausal Women
No full textThis work introduces a taxonomic classification for temporomandibular disorders (TMD), aiming to systematize the understanding and management of these complex conditions. The proposed classification comprises musculoskeletal disorders, including myofascial pain syndrome and non-inflammatory muscle disorders, and joint disorders, encompassing internal derangements, osteoarthrosis, and arthralgia. Etiological considerations distinguish between traumatic and non-traumatic TMD, with subtypes such as stress-related and idiopathic TMD. This structured framework provides clinicians and researchers with a systematic approach to categorize TMD, facilitating diagnosis and treatment planning. Stress-related TMD highlights the psychosocial aspect, while idiopathic TMD acknowledges the multifactorial nature of these disorders. As a dynamic tool, this classification accommodates future refinements, contributing to improved patient care and the advancement of TMD research. Overall, the proposed taxonomy serves as a valuable guide in navigating the diverse landscape of temporomandibular disorders
Awareness of Amalgam Versus Composite as a Restorative Material- A Knowledge, Attitude and Practice Survey Analysis Among Dental Practitioners and Patients
No full textThis study investigates the awareness, knowledge, attitudes, and practices of dental practitioners and patients regarding the choice between dental amalgam and composite resin as restorative materials. A cross-sectional descriptive survey involving 111 dentists and 114 patients was conducted, utilizing tailored questionnaires to explore preferences, safety considerations, and decision-making factors. Results revealed a significant awareness gap among patients regarding the potential harmful effects of mercury in dental amalgam, contrasting with dentists who exhibited high awareness of safety concerns. Patient preferences leaned towards amalgam, citing longevity and cost, while dentists favored composite resin due to safety considerations. The study underscores the need for improved patient education, continuous professional development, and environmentally conscious decision-making in restorative dentistry
Post Insertion Problems Faced by the Complete Denture Wearers Visiting a Dental School – A Survey
No full textThis study explores the challenges faced by complete denture wearers visiting a dental school, aiming to provide insights into the physical, clinical, and other denture-related problems encountered by this specific group of individuals. Edentulism, whether partial or complete, is recognized as a significant marker of oral health and an indicator of the effectiveness of preventive and treatment modalities within the healthcare system. The objectives of the study are threefold: firstly, to evaluate the problems faced by complete denture wearers through a questionnaire-based approach; secondly, to analyze the underlying reasons for these challenges; and thirdly, to guide dental students in understanding and addressing the identified problems. The methodology involves a survey-based study conducted in a dental school, ensuring economic accessibility for patients in rural areas. The study includes 125 participants who have sought assistance for complete dentures. The questionnaire, designed as a closed-ended tool, encompasses three categories: physical problems faced by patients, clinical observations, and other denture-related issues. Inclusion criteria focus on completely edentulous patients wearing complete dentures, ensuring specificity, while exclusion criteria exclude partially edentulous patients with removable partial dentures. The survey, administered in the local/regional language, aims to capture a comprehensive understanding of the challenges faced by elderly individuals relying on complete dentures. The literature review contextualizes the study within the broader landscape of oral health, emphasizing the impact of edentulism on various aspects of life. It highlights the challenges associated with complete denture usage, clinical considerations, existing interventions, and the importance of educating dental professionals. The synthesis of existing knowledge serves as a foundation for the study, contributing to the ongoing dialogue surrounding challenges and solutions in the realm of complete denture care. In conclusion, this study aspires to contribute valuable insights into the nuanced problems faced by complete denture wearers, offering a holistic understanding that can inform improved patient care and guide the education of future dental professionals. The findings are expected to enhance the proactive management of complete denture challenges and foster a collaborative approach between patients, practitioners, and dental students
Factors Affecting Stress among Dental Undergraduates
No full textThis study aims to comprehensively explore the factors contributing to stress among dental undergraduates in the unique landscape of Indian dental education. Acknowledging the global prevalence of stress in the dental profession, this research addresses the dearth of literature specifically focusing on stressors within the Indian context, particularly in the region surrounding the School of Dental Sciences at KIMSDU Karad. The study adopts an institutional cross-sectional design, targeting undergraduate students from the 2nd year to interns, providing a diverse representation of academic stages. The data collection instrument, a self-administered questionnaire distributed as a Google Form, is a modified version of the Dental Environmental Stress (DES) survey. This adaptation ensures cultural relevance and linguistic appropriateness for the Indian dental environment. The questionnaire encompasses six domains—academic performance, clinical and patient responsibility, faculty relations, personal issues, accommodation, and professional identity/career—providing a holistic view of potential stressors. Ethical considerations form a foundational aspect of the study, with approval obtained from the Institutional Ethics Committee. The voluntary participation of students emphasizes the importance of informed consent and ethical research practices. Upon data collection, rigorous statistical analysis, including descriptive statistics and inferential methods, will be employed to derive meaningful insights. The objective is to identify patterns, associations, and correlations within the identified stress domains. The significance of this research lies in its potential to uncover nuanced stressors specific to Indian dental education. The findings aim to contribute not only to the academic discourse on dental education but also to the development of targeted interventions and stress management programs. By understanding the unique stress landscape faced by dental undergraduates, this study seeks to pave the way for fostering a supportive learning environment and enhancing the overall well-being of future dental professionals in India. In conclusion, this abstract encapsulates the study\u27s purpose, methodology, and potential contributions, providing a snapshot of the research\u27s significance in addressing a critical gap in the understanding of stress among dental undergraduates in the Indian context
RNA Modifications and Epigenetics Emerging Players in Gene Regulation
No full textTraditional genetic paradigms do not fully explain the regulation of gene expression, with RNA modifications and epigenetic mechanisms emerging as key components. This review delves into the dynamic interactions between epigenetics and RNA alterations, explaining how they work together to control gene regulation. RNA modifications, which include a variety of changes such as 5-methylcytosine (m5C), pseudouridine, N6-methyladenosine (m6A), and others, are complex changes that affect the stability, translational efficiency, and localization of RNA molecules. Their intricate network of writer, reader, and eraser proteins adds to the complex field of RNA epigenetics.
Furthermore, a complex regulatory interplay is revealed by the convergence of RNA alterations with epigenetic marks such DNA methylation and histone modifications. The co-localization of chromatin and RNA changes raises the possibility of cross-regulation, which could influence the patterns of gene expression. The interdependence of RNA modifiers and epigenetic enzymes is highlighted by their crosstalk, which affects cellular functions and gene expression.
Moreover, illnesses including cancer, neurological disorders, and metabolic problems are increasingly linked to dysregulation of RNA alterations and epigenetic landscapes. These regulatory layers\u27 importance as therapeutic targets and diagnostic biomarkers is highlighted by perturbations in them.
Novel therapeutic opportunities arise from utilizing the regulatory capacity of RNA alterations and epigenetic markings. Targeting writer, reader, and eraser proteins using precision medicine techniques allows for customized therapies; RNA-based medicines and epigenetic modifiers show promise in managing diseases.
A new paradigm for comprehending biological processes and illness mechanisms is revealed by revealing the complementary functions of RNA alterations and epigenetics in gene regulation. Advancements in technology, clinical translations, and ongoing investigation of their interplay will bring about revolutionary shifts in medicine and biology, opening the door to more individualized treatments and better approaches to managing disease
Antibiotic Resistance Crisis Strategies for Combating Emerging Threats
No full textThe global rise of antibiotic resistance threatens public health and requires immediate action to address this catastrophe. This comprehensive overview examines antibiotic resistance\u27s evolutionary mechanisms, public health effects, and many prevention methods.
Antibiotic resistance evolves through genetic mutations, horizontal gene transfer, and antibiotic-induced selective pressures. Understanding these pathways is essential to understanding bacteria\u27s adaptability and multidrug-resistant strains. Multidirectional studies emphasize the need for novel medication discoveries and alternate therapy to combat growing resistance mechanisms.
Antibiotic resistance affects public health outside clinical settings, including socioeconomic burdens and treatment results. The rise of multidrug-resistant infections increases morbidity, mortality, and healthcare expenses. Antibiotic stewardship initiatives, interdisciplinary cooperation, and strong policy interventions are needed to address these issues.
Antibiotic stewardship initiatives optimize antibiotic use, promote smart prescribing, and improve surveillance to reduce resistance. To overcome resistance, healthcare professionals, researchers, and politicians must collaborate to develop new tactics and share knowledge.
Policy interventions are needed to regulate antibiotic usage in healthcare, agriculture, and the environment. To reduce resistant strains, national and global action plans emphasize coordinated efforts, surveillance systems, and public awareness campaigns.
To refill the antibiotic pipeline, novel drug development includes new substances, therapies, and technologies. Academic, business, and government relationships are essential for antibiotic innovation, research incentives, and regulatory success
Psychological Awakening Towards Politics Among The Mizos In The North-East Region Of India
No full text(The precise origins of the Mizos have remained undisclosed until now. Historians and scholars have only been able to provide conjectures and hypotheses regarding the origin of the Mizo tribe. During the course of their research, numerous intellectuals and scholars have postulated that the Mizo people belong to the Tibeto-Burman family, which is a subset of the larger Mongolian race. The history of the Mizo people can be traced back to the time when British officers first encountered the Lushai Hills. The British officers were captivated by the rich culture and heritage of the Mizo people, prompting them to extensively investigate their history and traditions. These findings were documented by the British and subsequently published as scholarly books on Mizo history, which continue to be regarded as valuable sources of information. It was during the period of British rule that the Mizo people began to actively participate in politics and express their opinions on various matters. The establishment of political parties by the Mizo people marked a significant milestone in their political journey and heralded a new era in Mizo politics. Building upon this premise, this paper aims to explore the historical factors behind the Mizo people\u27s initial interest in politics and the formation of political parties by the Mizos
A Review On Importance Of Kangen Water
No full textKangen Water helps remove free radicals from the body and reactivates important cells, including DNA. It enhances the immune system and improves the self-healing power of the body. Kangen water, thanks to its powerful electrolysis system, is capable of producing Active Hydrogen, a component which plays a very important role in our health. Kangen water is Alkaline Water, antioxidant and micro-clustered; filled with active hydrogen molecules. It is widely known for producing water which caters to different purposes ranging from cleaning and beauty to cooking and drinking. The activated water is produced via electrolysis, a process by which water is decomposed into “alkaline” and “acidic. Because of this process, the water acquires totally different qualities, turning it into a preventive remedy for many diseases. Activated water, which is also known as “alkaline” and “acidic”, increasingly has more application areas. Activated Water contains active Hydrogen, and its high concentration leads to its healing powe
ROLE OF SOIL BACTERIA IN PLANT NUTRITION - CURRENT AND FUTURE ASPECTS
No full textThe soil has a wide variety of microorganisms that are part of a varied ecosystem that includes plants. It has long been understood that some of these microorganisms, such as nitrogen-fixing symbiotic bacteria or mycorrhizal fungi, play significant roles in plant performance by enhancing mineral nutrition. However, only recently have researchers begun to identify the full range of microorganisms connected to plants and their potential to replace artificial agricultural inputs. The understanding of the make-up and behaviour of rhizospheric microbiomes has advanced significantly in recent years. Long-term use of these fertilisers frequently results in a drop in pH and exchangeable bases, rendering them inaccessible to crops and lowering agricultural productivity. Farmers have become increasingly reliant on chemical sources of nitrogen and phosphorus to solve this issue and increase plant yield
Reconsidering Models Of Organizational Transformation Maturity
No full textOrganizational culture encompasses a set of characteristics, including norms, routines, and unspoken rules that dictate how activities are conducted within an organization. The maturity of an organization\u27s culture can be assessed using various maturity models (MMs), and aligning the organizational culture with an appropriate MM has the potential to accelerate project and business performance. A MM is a descriptive model outlining the stages through which organizations progress as they define, implement, evolve, and enhance their processes. Typically, these stages include the initial level, repeatable level, defined level, managed level, and optimizing level (Becker et al., 2009), illustrating the organization\u27s capacity for continuous improvement.
Maturity models play a crucial role in helping companies understand their current maturity level and guide them in improving specific disciplines. By posing questions and developing action plans, MMs serve as a tool for organizations to assess and enhance their capabilities