Institute of Psychology,Chinese Academy Of Sciences
Not a member yet
6627 research outputs found
Sort by
A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus
No full textHeschl's gyrus (HG) is a core region of the auditory cortex whose morphology is highly variable across individuals. This variability has been linked to sound perception ability in both speech and music domains. Previous studies show that variations in morphological features of HG, such as cortical surface area and thickness, are heritable. To identify genetic variants that affect HG morphology, we conducted a genome-wide association scan (GWAS) meta-analysis in 3054 healthy individuals using HG surface area and thickness as quantitative traits. None of the single nucleotide polymorphisms (SNPs) showed association P values that would survive correction for multiple testing over the genome. The most significant association was found between right HG area and SNP rs72932726 close to gene DCBLD2 (3q12.1; P=2.77x10(-7)). This SNP was also associated with other regions involved in speech processing. The SNP rs333332 within gene KALRN (3q21.2; P=2.27x10(-6)) and rs143000161 near gene COBLL1 (2q24.3; P=2.40x10(-6)) were associated with the area and thickness of left HG, respectively. Both genes are involved in the development of the nervous system. The SNP rs7062395 close to the X-linked deafness gene POU3F4 was associated with right HG thickness (Xq21.1; P=2.38x10(-6)). This is the first molecular genetic analysis of variability in HG morphology
Affective Instability in Personality Disorder Patients is Inversely Correlated with Anterior Cingulate Activity during Habituation to Negative Stimuli
No full textSuccessful in Science Education and Still Popular: A pattern that is possible in China rather than in Germany or Russia
No full textAcross several countries, science is often regarded as unpopular and a male-dominated domain. Furthermore, the number of students who are interested in science education or intend to work in the field of science is relatively low. This might be due to expectations adolescents hold towards science and successful scientists. The current cross-national study investigates the expectations of students in relation to highly achieving peers in science education in the three countries China, Germany and Russia (N=420). Students were asked to indicate their expectations about two fictitious new classmates with respect to three categories: intelligence, social competence and eagerness. Besides national differences, differences concerning the gender of the participating students, the gender of the target students (fictitious highly achieving students in science education) and interaction effects were investigated. Whereas the effects of gender and target gender are inconsistent and negligible, there are significant national differences. Notably, Chinese students hold the most positive expectations about successful peers in science education. The results are discussed with regard to possible explanations and educational consequences
Long-term academic stress increases the late component of error processing: An ERP study
No full textExposure to long-term stress has a variety of consequences on the brain and cognition. Few studies have examined the influence of long-term stress on event related potential (ERP) indices of error processing. The current study investigated how long-term academic stress modulates the error related negativity (Ne or ERN) and the error positivity (Pe) components of error processing. Forty-one male participants undergoing preparation for a major academic examination and 20 non-exam participants completed a Go-NoGo task while ERP measures were collected. The exam group reported higher perceived stress levels and showed increased Pe amplitude compared with the non-exam group. Participants' rating of the importance of the exam was positively associated with the amplitude of Pe, but these effects were not found for the Ne/ERN. These results suggest that long-term academic stress leads to greater motivational assessment of and higher emotional response to errors. (C) 2014 Elsevier B.V. All rights reserved
Galanthamine, an acetylcholine inhibitor, prevents prepulse inhibition deficits induced by adolescent social isolation or MK-801 treatment
No full textAdolescence is a critical period for neurodevelopment. MK-801 treatment and social isolation are important animal models for various neurodevelopmental disorders. Dysfunctions in the central cholinergic system are involved in creating the cognitive deficits observed in neurological diseases. In the present study, we aimed to investigate whether the acetylcholinesterase inhibitor galanthamine could reverse pre-cognitive prepulse inhibition (PPI) deficits and spatial learning deficits of adult rats in the Morris water maze. We induced these effects using either adolescent MK-801 treatment or social isolation from postnatal day (PND) 38-51. Our results showed that both adolescent social isolation and MK-801 treatment impaired PPI in adult rats, but neither had an effect on spatial learning. Furthermore, galanthamine injections over 7 days significantly enhanced PPI of normal rats and improved PPI disruption induced by adolescent pharmacological and rearing interventions. The results suggest that acetylcholinesterase inhibitors, such as galanthamine, might have the potential to improve pre-cognition in neurodevelopmental diseases by improving auditory sensory gating. (C) 2014 Elsevier B.V. All rights reserved
Liking for name predicts happiness: A behavioral genetic analysis
No full textResearch has established that humans tend to view their names in a positive light and liking for one's name is positively associated with subjective well-being. In this study, the genetic basis of individual difference in liking for one's name was examined in a survey of 304 pairs of twins from Beijing, China. Results showed that (1) liking for name was heritable (47%), while unique environment also played a role (53%); (2) the positive association between name-liking and subjective well-being is driven by common genetic (r(g):.21-.41) and non-shared environmental (r(e):.14-.22) influences. These findings have provided novel evidence that liking for one's name is a fundamentally important trait and further shed light on the understanding of implicit self-esteem. (C) 2014 Elsevier Ltd. All rights reserved
Genetic and Environmental Etiologies of Adolescent Dysfunctional Attitudes: A Twin Study
No full textDespite the importance of dysfunctional attitudes in the development and maintenance of depression, little is known about the etiological origin of dysfunctional attitudes. The Dysfunctional Attitudes Scale for Children was administered to 674 adolescent twins derived from the Beijing Twin Study (BeTwiSt). Four hundred and thirty-nine monozygotic and 235 same-gender dizygotic twin pairs were included. Approximately 54% were females. The age range of the twins was 11-17 years. Model-fitting analyses were conducted. Biometric genetic model-fitting estimates indicated that additive genetic factors accounted for 31% (95% CI: 11%, 45%) of variance in adolescent dysfunctional attitude. The influence of shared environmental factors was small and negligible (9% [95% CI: 0%, 27%]). Non-shared environmental factors explained 60% (95% CI: 55%, 66%) of variance. Equating the estimate parameters across gender or age groups resulted in a non-significant difference of model fit, but there were trends suggesting higher heritability in females and older adolescents. Our results provide evidence for moderate heritability of dysfunctional attitudes in adolescents. Dysfunctional attitudes can be used as an endophenotype to identify risk genes for depression
Complex motivated behaviors for natural rewards following a binge-like regimen of morphine administration: mixed phenotypes of anhedonia and craving after short-term withdrawal
No full textThe anhedonia-like behaviors following about 1-week withdrawal from morphine were examined in the present study. Male rats were pretreated with either a binge-like morphine paradigm or daily saline injection for 5 days. Three types of natural reward were used, food reward (2.5, 4, 15, 30, 40, and 60% sucrose solutions), social reward (male rat) and sexual reward (estrous female rat). For each type of natural stimulus, consummatory behavior and motivational behaviors under varied testing conditions were investigated. The results showed that the morphine-treated rats significantly reduced their consumption of 2.5% sucrose solution during the 1-h consumption testing and their operant responding for 15, 30, and 40% sucrose solutions under a fixed ratio 1 (FR1) schedule. However, performance under a progressive ratio (PR) schedule increased in morphine-treated rats reinforced with 60% sucrose solution, but not in those reinforced with sucrose concentrations lower than 60%. Pretreatment with morphine significantly decreased the male rats' ejaculation frequency (EF) during the 1-h copulation testing, and impaired the maintenance of appetitive motivations to sexual and social stimuli under a free-approach condition. Moreover, the morphine-treated rats demonstrated a diminished motivation to approach social stimulus in the effort-based appetitive behavior test but showed a remarkable increase in motivation to approach sexual stimulus in the risky appetitive behavior test. These results demonstrated some complex motivated behaviors following about 1 week of morphine withdrawal: (1) The anhedonia-like behavior was consistently found in animals withdrawn from morphine. However, for a given reward, there was often a dissociation of the consummatory behaviors from the motivational behaviors, and whether the consummatory or the motivational anhedonia-like behaviors could be discovered heavily depended on the type and magnitude of the reward and the type of testing task; (2) These anhedonia-like behaviors coexisted with a craving for the high-incentive reward which was evidenced by the increased PR performance for the 60% sucrose solution and the heightened risky appetitive behavior for the sexual stimulus. The craving for the high-incentive reward alongside with the impaired inhibitory control in drug-withdrawn subjects might form one of psychological mechanisms underlying drug relapse after withdrawal
Bilingual Cognitive Control in Language Switching: An fMRI Study of English-Chinese Late Bilinguals
No full textThe present study explored the bilingual cognitive control mechanism by comparing Chinese-English bilinguals' language switching in a blocked picture naming paradigm against three baseline conditions, namely the control condition (a fixation cross, low-level baseline), single L1 production (Chinese naming, high-level baseline), and single L2 production (English naming, high-level baseline). Different activation patterns were observed for language switching against different baseline conditions. These results indicate that different script bilingual language control involves a fronto-parietal-subcortical network that extends to the precentral gyrus, the Supplementary Motor Area, the Supra Marginal Gyrus, and the fusiform. The different neural correlates identified across different comparisons supported that bilingual language switching involves high-level cognitive processes that are not specific to language processing. Future studies adopting a network approach are crucial in identifying the functional connectivity among regions subserving language control
A global energy optimization framework for 2.1D sketch extraction from monocular images
No full textThe 2.1D sketch is a layered image representation, which assigns a partial depth ordering of over-segmented regions in a monocular image. This paper presents a global optimization framework for inferring the 2.10 sketch from a monocular image. Our method only uses over-segmented image regions (i.e., superpixels) as input, without any information of objects in the image, since (1) segmenting objects in images is a difficult problem on its own and (2) the objective of our proposed method is to be generic as an initial module useful for downstream high-level vision tasks. This paper formulates the inference of the 2.1D sketch using a global energy optimization framework. The proposed energy function consists of two components: (1) one is defined based on the local partial ordering relations (i.e., figure-ground) between two adjacent over-segmented regions, which captures the marginal information of the global partial depth ordering and (2) the other is defined based on the same depth layer relations among all the over-segmented regions, which groups regions of the same object to account for the over-segmentation issues. A hybrid evolution algorithm is utilized to minimize the global energy function efficiently. In experiments, we evaluated our method on a test data set containing 100 diverse real images from Berkeley segmentation data set (BSDS500) with the annotated ground truth. Experimental results show that our method can infer the 2.10 sketch with high accuracy. (C) 2014 Elsevier Inc. All rights reserved
Access Repository Dashboard
Do you manage Institute of Psychology,Chinese Academy Of Sciences? Access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard!