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Finding the Balance The Effects of α-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin, and cholesterol Bacteroides vulgatus and Clostridium bolteae
Get PDFAtherosclerosis is a cardiovascular disease that is characterized by the hardening of arteries through the formation of cholesterol plaques. Cyclodextrins could potentially treat atherosclerosis by shrinking plaques. These cyclic oligosaccharides can make complexes with cholesterol but have also shown toxic side effects. This study looked for potential negative effects of cyclodextrins and cholesterol on gut bacteria. It was hypothesized that Bacteroides vulgatus will have decreased growth when grown in broth with cholesterol. In contrast, Clostridium bolteae will have decreased growth when grown in broth with cyclodextrins. Due to the fact that these bacteria are anaerobic, Clostridium bolteae and Bacteroides vulgatus, were grown using GAM broth under CO2. Data was collected by using a spectrophotometer to measure changes in bacterial growth throughout the growth cycle. Each bacteria was treated with one of three chemicals at one of three concentration to make a total of 9 different conditions. α-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin, and cholesterol with concentrations of 1 mM, 10 mM, and 100 mM. The slopes of the log phase of bacterial growth were compared using a two tailed T-Test with α=0.05. Growth of Clostridium bolteae was significantly inhibited for most of the cyclodextrin trials and all the cholesterol concentrations. Bacteroides vulgatus growth was inhibited by 100 mM concentrations of cholesterol and α-cyclodextrins. Interestingly, Bacteroides vulgatus growth was significantly increased when grown with 1 mM and 10 mM concentrations of cholesterol. Continued research is needed to determine when cholesterol concentrations become harmful to Bacteroides vulgatus. Clostridium bolteae needs further research to understand the 10 mM α-cyclodextrin trial that did not show significant inhibition. The results demonstrate that cyclodextrins are associated with inhibited growth for these two gut bacteria but expansion of this test to other gut bacteria is key for a deeper understanding of the impact that cyclodextrins would have on the gut microbiome as a whole
Department of Music Programs 2020-2021
Get PDFIncludes the music program flyers for the year 2020-2021. Many performances were held in unique venues due to covid-19 health & safety protocols.https://digitalcommons.olivet.edu/musi_prog/1051/thumbnail.jp
ASSESSMENT OF STRENGTHS-BASED INTERVENTIONS ON FIRST-YEAR MEDICAL STUDENTS
Get PDFIn the quest for a doctoral degree many candidates fail to meet their milestone accomplishment. It is estimated that approximately 30% of individuals who pursue a doctoral degree will not finish. Medical school has been found to be a very intensive program to pursue for many who begin the journey. Despite its difficulty, 81.6% to 84.1% of medical students achieve the status of medical practitioner, within a three-to-four year program. Despite the seemingly high completion rate, the achievement gap has further implications on physician shortages. The researcher conducted a quantitative study to determine the impact training first-year medical students using the CliftonStrengths® assessment would have on resiliency, self-efficacy and academic performance at a large Midwestern medical university. The participants consisted of two groups (n = 87), 30 untrained participants and 57 trained participants. An independent t-test was conducted and used to calculate resiliency, self-efficacy, and academic performance on two course grades. All test data were analyzed, and the results found no outcomes to be statistically significant. The current study is the first known to be conducted with students in a medical school setting utilizing the CliftonStrengths® assessment. Future studies utilizing a larger population of participants, particularly over a longer period of time that incorporates the full three-year or four-year curriculum within medical school education is encouraged
Examining the Implementation of Functional Behavior Assessments and Behavior Intervention Plans
No full textThere is a need to understand and improve the skills of school staff regarding functional behavior assessments (FBAs) and behavior intervention plans (BIPs). Students who exhibit problematic behaviors are at risk for negative outcomes in school and in adulthood. Students with emotional disabilities, African American students, and male students have the most risk. The purpose of this study was to explore teachers’ and administrators’ skills and knowledge as they relate to developing and implementing FBAs and BIPs and to identify training needs in this area. The study may be of interest to school staff and others seeking to provide behavioral support to students who exhibit problematic behaviors. A quantitative non-experimental design was used. Data was collected from 163 participants using an electronic survey instrument derived from two published studies, Couvillon et al. (2009) and Pindiprolu, Peterson, and Berglof (2007). There was a statistical significance difference which showed that administrators were more likely to initiate an FBA than teachers. There was not a difference between groups in the extent to which the intensity of problem behavior is related to the likelihood of an FBA. Teachers showed a higher need for training in FBAs and BIPs than administrators. Schools should implement a school-wide behavior system, maintain effective classroom management strategies, utilize culturally responsive strategies, and meet the needs of individual students with the use of FBAs and BIPs. Improving school staff knowledge and skill set in regard to FBAs and BIPs will require focused effort and training. Further research is warranted.
Cohort X
The pandemic and personality: A cross-sectional comparison of personality trait scores
No full textPresentation Location: Warming House, Olivet Nazarene University
Abstract
While personality traits are thought to be stable, personality is also known to be the result of an interaction between dispositional and environmental factors. Because 2020 has introduced a number of unexpected and challenging situations into our society, we compared scores from three different indices (The 20-Item Mini-IPIP, Donnellan, Oswald, Baird, & Lucas, 2006; The Big Five Test, Brody & Ehrlichman, 1998; & the Big Five Inventory, John & Srivastava, 1999) of openness to experience, conscientiousness, extraversion, agreeableness, and neuroticism for three different cohorts (2018, 2019, & 2020). We did not suspect any changes in terms of openness to experience, conscientiousness, or extraversion across the three cohorts. However, we thought it was possible that agreeableness scores would be lower for 2020. We also expected neuroticism scores to be higher for 2020. Results indicated that there were no significant differences for any of the personality traits across the three different cohorts. Results will be discussed in light of an interactionist view of personality, states versus traits, and the psychometric properties of these three inventories
An Exploratory Study of Emotional Intelligence Characteristics Between Disciplines in Higher Education and Suggested Curriculum Adjustments
No full textEmotional Intelligence (EI) may be more important to the success of college students than cognitive intelligence and technical skills combined. Recent research has primarily focused on EI in the workplace. However, implications for improving EI skills of college undergraduate students before they enter the workforce appears to be lacking. This quantitative research examined the Emotional Intelligence levels of five different majors to identify differences based on area of study, gender, or other demographic factors. Subsequently, the study aimed to provide suggestions for curriculum development with a goal to better expose students to EI themes. An online survey was offered to undergraduate students at a private, Christian university in the Midwest. The process resulted in 391 usable survey responses from five different majors, representing a student body of approximately 4,700 from over 40 states. The purposive sample provided enough respondents to achieve a 95% confidence level in the results. The survey included questions from the Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF) with factor analysis providing scores of Well-Being, Self-Control, Emotionality, Sociability and Global Trait EI. Appropriate statistics and techniques to provide basic descriptive, correlation, normality, ANOVA, and t-tests were used and, in some cases, suitable non-parametric equivalents. Students were also polled regarding their exposure to Emotional Intelligence topics in the current curriculum. Additionally, demographic questions were posed to determine why differences might exist in Emotional Intelligence levels. This research partially confirmed the differences in the Emotionality of students from different majors. Specifically, evidence of variations in EI of Nursing, Business, Education, Engineering, and Religion/Theology students were found to be significant, in certain areas. Generally accepted stereotypes of gender differences were confirmed by this research. Somewhat surprisingly, this study did not uncover that other demographic factors such as birth order, religious background, hometown size, and size of high school impacted their EI levels. Emotional Intelligence varies with individuals and can be measured. This study identified the similarities and differences in EI of students. Exposure to EI topics in higher education appear to be lacking. Research outcomes included implications for EI curriculum development and suggestions for each major
Mothers and Sons: Queen Mothers of Judah and the Religious Trends that Develop During Their Sons\u27 Reign
No full textThis thesis studies the implicit relationship between the early gĕbîrôt of the Judaean Monarchy and the religious trends during the reigns of their sons. While previous studies had noted a relationship between the origins of the gĕbîrâ and the religious evaluation of her son, a systematic treatment on this subject has not yet been written. After necessary background information has been explored, this study systematically analyzes the first three queen mothers of Judah (Bathsheba, Naamah, and Maacah) in view of their ethnic or national origins, the theophoric nature of their sons’ names, and their implicit religious and political effects upon their sons’ reigns. In a final section, it compares these findings with later gĕbîrâ of righteous kings within the Judaean Monarchy (Abijah and Jedidah). This study confirms that pagan mothers indeed have sons that follow pagan gods, and Yahwistic mothers have devout sons, but it seeks to develop this trend in more depth
Measuring the decrement times of volatile anesthetics in Drosophila melanogaster using gas chromatography-mass spectrometry
No full textPresentation Location: Warming House, Olivet Nazarene University
Abstract
Background
Model organisms are widely used in research, especially in the context of complex situations. One model organism that has been widely used is the common fruit fly, Drosophila melanogaster (D. mel). D. mel are most commonly used in the context of genetics, but they have also been widely used in research focusing on general anesthetics. One value that has not been measured in D. mel, however, as it relates to general anesthetics, is the decrement times. This is what was the present research set out to determine.
Methods
The anesthetics studied in this research were isoflurane and sevoflurane. Flies were exposed to 40 µL of anesthetic in a centrifuge tube for 10 minutes, after which the flies were allowed a recovery period of a set time. In the case of the control group, this time was 0 minutes. The anesthetic was then extracted using dichloromethane (DCM) and enflurane was added as an internal standard.
Results
The decrement times of male flies with isoflurane were found to be around 30 seconds for the 50% decrement, 2 minutes for the 80%, and 3 minutes for the 90% decrement. With sevoflurane in male flies, the values were found to be around 2 minutes for the 50% decrement and 3 minutes for the 80% decrement. For female flies the values found with isoflurane were found to be about 30 seconds for the 50% decrement and 4 minutes for the 80% decrement. The values found using sevoflurane with female flies were about 5 minutes for a 50% decrement time, but the values found in female flies with sevoflurane were not consistent.
Conclusions
Though the data with sevoflurane were inconsistent, those collected with isoflurane give valuable insight into general anesthetics. This information can be used in future work involving drosophila flies and anesthetics in order to gain a deeper understanding of how inhalational anesthetics work
Essity Automating Converting Line #360
No full textSenior Engineering capstone project focused on the development of a system of sensors and high-level logic that will detect product jams and then stop continuous conveyor movement.
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#360 creates 3 types of small toilet tissue products: wrapped (which is unaffected by this project), Banded plugged, and banded non-plugged. The conveyor destroys the banded product if there is a downstream stop and the conveyors upstream have not shut off. The belts keep moving, which tears up the tissue.It is desired to have the project team design a system of eyes and logic for the conveyor system to appropriately shut down or slow conveyors when there is a downstream stop. It is desired to have a system of eyes and receivers in multiple positions, which communicate to the conveyor system to slow and/or shut down some stretches of the system as needed to eliminate the destruction of product. It is preferred if the design contains multi-tiered logic which slows the conveyor when a backup is sensed and allows the downstream to catch up