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「田舎」武将の王敦を語る人々：『世説新語』豪爽篇と荊州桓氏幕下の僚属たち
Get PDF規定により本文ファイルは発行から6ヶ月後の2024年9月13日に公開departmental bulletin pape
タスク・アンビエント照明における照度バランスに関する研究 ： 照度の嗜好を考慮した定常順応状態の推定と配光特性指標の導入による設計資料の提案
Get PDF奈良女子大学博士(学術)doctoral thesi
【内容の要旨及び審査の結果の要旨】Reading the Body: John Donne's Funeral Elegies, Letters, and Devotions
Get PDF奈良女子大学博士（文学）doctoral thesi
【博士論文本文の要約】Direct and indirect effects in rice ecosystems: learning chain involving carrion crows and apple snails
Get PDF奈良女子大学博士（理学）doctoral thesi
A CQI and Hysteretic-Based Decision Algorithm to Prevent Handover Failures for Pedestrian Mobility in Mobile Communication HetNet
No full textIn current mobile communication networks, handover substantially influences the performance of heterogeneous networks (HetNet). The decision process and trigger timing of the handover decision algorithm (HDA) are integral aspects of handover and are indispensable for mobile user equipment (UE). However, the major A3RSRP (reference signal received power) HDA with the parameter of handover margin (HOM) used in co-frequency environments has poor performance with low-speed pedestrian scenarios in HetNet, including high handover failure (HoF) ratio, frequent handover (FHO), and high number of HoFs. In this paper, we focus on reducing the HoF ratio and propose a novel CQI and hysteretic (CH)-based HDA using downlink channel quality indicator (CQI) and hysteretic control (HC). This novel HDA enables the cell to check the downlink CQI of the UE during HDA, thereby correctly determining the trigger timing of the handover. Moreover, the cell can use the HC to dynamically adjust the HOM based on the CQI of the UE to adapt the handover to the HetNet environment. We evaluate and compare the performance of the CH and A3RSRP HDAs in three scenarios with different speeds, each with multiple HOM settings. The ns-3 simulation results indicate that the CH HDA shows a maximum improvement of 100% in HoF ratio and 5% and 100% in the number of handovers and HoFs, respectively, in the small-scale environment with a speed of 0.5 m/s and an initial HOM of 2.0 dB, while the CH HDA shows a minimum improvement of -4% in HoF ratio and 58% and 44% improvement in the number of handover and HoFs, respectively, in the large-scale environment with a speed of 0.5 m/s and an initial HOM of 3.0 dB, compared with the A3RSRP HDA.journal articl
Circular RNAs, Noncoding RNAs, and N6-methyladenosine Involved in the Development of MAFLD
No full textNoncoding RNAs (ncRNAs), including circular RNAs (circRNAs) and N6-methyladenosine (m6A), have been shown to play a critical role in the development of various diseases including obesity and metabolic disorder-associated fatty liver disease (MAFLD). Obesity is a chronic disease caused by excessive fat accumulation in the body, which has recently become more prevalent and is the foremost risk factor for MAFLD. Causes of obesity may involve the interaction of genetic, behavioral, and social factors. m6A RNA methylation might add a novel inspiration for understanding the development of obesity and MAFLD with post-transcriptional regulation of gene expression. In particular, circRNAs, microRNAs (miRNAs), and m6A might be implicated in the progression of MAFLD. Interestingly, m6A modification can modulate the translation, degradation, and other functions of ncRNAs. miRNAs/circRNAs can also modulate m6A modifications by affecting writers, erasers, and readers. In turn, ncRNAs could modulate the expression of m6A regulators in different ways. However, there is limited evidence on how these ncRNAs and m6A interact to affect the promotion of liver diseases. It seems that m6A can occur in DNA, RNA, and proteins that may be associated with several biological properties. This study provides a mechanistic understanding of the association of m6A modification and ncRNAs with liver diseases, especially for MAFLD. Comprehension of the association between m6A modification and ncRNAs may contribute to the development of treatment tactics for MAFLD.journal articl
Asymmetric autocatalysis with amplification of enantiomeric excess utilizing chiral crystals of achiral o-terphenyls as chiral triggers
No full textChiral crystals composed of achiral hydrocarbon o-terphenyl and its dimethoxy derivative, 4′,5′-dimethoxy-o-terphenyl have been successfully employed as chiral triggers in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde. In conjunction with asymmetric autocatalysis, that is, the Soai reaction, 5-pyrimidyl alkanol with remarkably enhanced enantiomeric excess (up to >99.5% ee) has been synthesized. The resulting 5-pyrimidyl alkanols exhibit the absolute configurations corresponding to those of the enantiomorphic o-terphenyls. These current findings highlight the capability of asymmetric autocatalysis to establish a connection between the crystal chirality of achiral hydrocarbon, such as o-terphenyls and the highly enantioenriched organic compounds.journal articl