Indian Journal of Research in Homoeopathy
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In vivo study of homoeopathic preparation of Gymnema sylvestre mother tincture, 30C and 200C on streptozotocin-induced diabetic rats
Get PDFIntroduction: Gymnema sylvestre (GS) is a medicinal plant commonly used in complementary medicine to treat diabetes mellitus. This plant is proven scientifically to reduce blood glucose levels in the diabetic condition. However, till date, only little literature is published about the efficacy of GS prepared homoeopathically. Objective: In this study, we assessed the efficacy of homoeopathic preparation of GS (HPGS) in Q, 30C and 200C potencies in streptozotocin-induced diabetic rats. Materials and Methods: Diabetic rats were administered with 4.7 mL/kg of HPGS mother tincture (Q) for anti-hyperglycaemic efficacy on daily bases over a period of 14 days and HPGS Q, HPGS 30C and HPGS 200C potencies for dose-dependent testing on daily basis for 90 days. Results: On completion of treatment period, HPGS Q and HPGS 200C significantly reduced the blood glucose levels in diabetic rats (P \u3c 0.05). Conclusion: Current research findings showed that HPGS mother tincture and HPGS 200C have the ability to lower blood glucose levels in diabetic rats, suggesting its efficacy in vivo
Management of urolithiasis with individualised homoeopathy – A case report
Get PDFIntroduction: The population of the North-eastern region of India is prone to develop renal stones, and the prevalence and recurrence rate of renal stone disease is thus higher. A stone more than 0.5 cm diameter can cause painful ureteric obstruction. Stones of size more than 0.7 cm almost always require surgical intervention, as believed in conventional medicine. Repeated surgical interventions may remove obstruction but may not be a solution for altering the tendency for renal stone formation. Homoeopathy, an alternative system of medicine can offer holistic approach in treating such cases non-invasively. Case Summary: A 32 years old male patient presented with continuous severe pain in the left renal region for 15 days. A 1.0 × 0.4 cm calculus was found in the left distal ureter causing mild left-sided hydronephrosis as per computed tomography (CT) scan. According to symptoms similarity, homoeopathic medicine Tabacum was prescribed followed by Belladonna. Subsequently, the stone was expelled through urine. The pain was completely relieved, and the CT scan report showed no abnormality. On the basis of the patient’s constitution Calcarea carbonica was prescribed to remove the tendency to form the renal stone. This case of renal stone suggests that homoeopathic medicine can enable expulsion of a relatively bigger renal stones and check recurrence. However, more conclusive researches are required
A 15-mm urinary calculus expelled with homoeopathic medicine - A case report
Get PDFIntroduction: Renal or ureteric colic is an acute and severe pain caused by obstruction in the ureter. It usually occurs in the narrower areas of the ureter. It can be associated with severe pain, nausea, vomiting, urinary infections, haematuria, hydronephrosis, etc. Case Summary: A case of 15-mm calculus, lodged at the right ureterovesicular junction, presented with severe cutting pain extending downwards from the right lumbar region to the right groin area. The patient had severe pain at the conclusion of urination. Another calculus of size 10 mm in the lower calyx of the left kidney and 3.4-mm concretion in the right kidney was also detected. The homoeopathic medicine Sarsaparilla was given on the basis of totality of symptoms for 3 days. The pain reduced in 3 days and subsequent to an acute colicky pain and some bleeding, on the 11th day, the stone was expelled. This case report shows the potential of Homoeopathy in cases of large urinary calculi
Homoeopathic treatment of women with polycystic ovarian syndrome: A prospective observational study
Get PDFBackground: Polycystic ovarian syndrome (PCOS) is one of the most common hormonal disorders among women of reproductive age group and a leading cause of female sub-fertility. Objectives: This study was conducted to evaluate the effect of individualised homoeopathy on clinical and hormonal profile in women suffering from PCOS. Materials and Methods: A prospective, observational study was conducted from July 2015 to June 2017 at Homoeopathic Research Foundation, Lucknow, in which 80 cases were screened, and 38 cases fulfilling the eligibility criteria were enrolled. Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ) was used to evaluate the quality of life. Serum levels of follicle-stimulating hormone, luteinising hormone, progesterone, prolactin, estrogen, testosterone and insulin were tested at the baseline and 12 months of treatment. Eighteen patients completed the follow-up of 12 months. The analysis was done with \u27modified Intention to Treat\u27 approach. Results: The comparison of PCOSQ from baseline to 12 months in 34 patients using the paired t-test showed significant improvement in the overall PCOSQ of the patients (mean increase ± standard error: −2.3 ± 0.5; 95% confidence interval CI: -3.2 to -1.3 P = 0.001). The number of cysts in both ovaries reduced with a statistically significant difference. There was a mean reduction of two cysts on each side of the ovary. The most prescribed medicines were Calcarea carbonica (38.24%) and Lycopodium. (26.47%) accounting to 64.71% of the total medicines. Conclusion: The present study gives positive leads in the management of PCOS with Homoeopathic medicines. Controlled trials are further warranted
Preclinical updates of the homoeopathic medicines used in diabetes mellitus: A narrative review
Get PDFIntroduction: Homoeopathy, one of the most commonly employed alternative medicines globally, has a wide range of role in the management of diabetes. Screening of the action of homoeopathic medicines in diabetes on animal model not only helps in validating their antidiabetic potential but also aids in understanding their effect on living systems and their mechanism of action. The present review focusses on the collection of results of pre-clinical studies carried out on homoeopathic medicines employed in the management of diabetes. Methodology: PubMed, HomBRex portal, and published literature such as library catalogue were searched up to November 2019. The search terms employed were \u27Homoeopathy\u27, \u27Diabetes\u27 and their MeSH variations in PubMed and in HomBrex search was made using the condition \u27Diabetes\u27. Results: Fifteen studies were included in the review. Twenty medicines were evaluated for their antidiabetic efficacy either in vivo or in vitro. Most of the preclinical research on diabetes was carried out on Syzygium jambolanum and Cephalandra indica in mother tincture form and potencies, substantiating their effectiveness in the management of diabetes. Apart from the medicines discussed in the current review, there are many other medicines in Homoeopathy which are used to treat diabetes and these also should be validated scientifically for global acceptance by the scientific fraternity. Conclusion: Considering the hypoglycaemic potential, availability and cost-effectiveness of homoeopathic medicines, future research should focus on screening their effectiveness in the management of diabetic complications and other metabolic disorders
A case report of hyperuricaemia with nephrolithiasis treated with homoeopathy
Get PDFIntroduction: Hyperuricaemia is serum urate concentration exceeding the limit of solubility, leading to its precipitation and predisposing the affected persons to gout. The increased level of uric acid in urinary excretion can also lead to nephrolithiasis. It has also been implicated as an indicator for diseases such as metabolic syndrome, diabetes mellitus, cardiovascular disease and chronic renal disease. Whereas homoeopathic literature enlists many medicines for this condition, there is a paucity of evidence-based published studies. Case Summary: The case presented here reported with the complaint of renal stone secondary to high serum uric acid levels. A single homoeopathic medicine Lycopodium was prescribed after thorough case taking which led to improvement in subjective symptoms and objectively reflecting in gradually decreasing levels of serum uric acid after elimination of stone. During the course of treatment, old symptoms also re-appeared depicting improvement in accordance with Hering\u27s law of cure. The Modified Naranjo Criteria score after treatment was 8, which explicitly shows the positive causal attribution of the individualised homoeopathic medicine Lycopodium in this case. Homoeopathic treatment has shown favourable results in this case and demonstrates the scope of Homoeopathy in such cases
Homoeopathic pathogenetic trial of Cuprum aceticum: A multicentric, double-blind, randomized, placebo controlled trial
Get PDFBackground: Although the symptomatology of Cuprum metallicum is quite vast, its other salts have fragmentary proving. Thus, homoeopathic pathogenetic trial for Cuprum aceticum (Cu acet.) was taken up. Objective: To elicit the pathogenetic response to Cu acet. in homoeopathic potencies on healthy human provers. Materials and Methods: A multi-center, double-blind randomized, placebo controlled, trial was conducted at three centers of Central Council for Research in Homoeopathy. Proving was conducted on 50 relatively healthy provers selected after conducting the Pretrial Medical Examination. All the provers were given placebo during the first phase of the trial. In the next two phases, Cu acet. was administered in 6 C and 30 C potencies, in the intervention group (n = 34); and placebo in the placebo group (n = 16), after randomization. The proving data so generated on Cu acet. were compiled and analyzed at the proving-cum-data processing cell. Results: Out of 34 provers who were on actual drug trial, only 12 provers manifested symptoms. Twenty-six and 20 symptoms were manifested in 6C and 30C potency, respectively. Conclusion: The pathogenetic response elicited during the proving trial expands the scope of use of the homoeopathic medicine C. aceticum. The symptoms generated in this trial will carry more value when verified clinically
