Indian Journal of Research in Homoeopathy
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World Homoeopathy Day 2020: Connecting digitally during the adversities of COVID-19 lockdown
The Central Council for Research in Homoeopathy (CCRH), with support from the Ministry of AYUSH, Government of India, organised its first Webinar on World Homoeopathy Day on 10 April 2020 to commemorate the birth anniversary of the founder of Homoeopathy, Dr Samuel Hahnemann. Considering the need of hour and utilising the advancements of digital platforms, the CCRH decided to organise this webinar focusing on the role of Homoeopathy in COVID-19, for the homoeopathic fraternity and to unite them digitally. The webinar was inaugurated by Shri. Shripad Naik, Minister of State (IC), Ministry of AYUSH; Vaidya Rajesh Kotecha, Secretary, Sh. PK Pathak, Additional Secretary; and Sh. Roshan Jaggi, Joint Secretary from the Ministry of AYUSH, also graced the occasion with their live addresses. Keynote speaker Prof. George Vithoulkas, Director, International Academy of Classical Homeopathy, Dr Robbert V Haselen, Member, Homoeopathic Pharmacopeia of United States, and Prof. Aaron To, Director, Living Homoeopathy, Hong Kong, also joined in as valued speakers. Significant deliberations were also made by Dr V. K. Gupta, Chairman, Scientific Advisory Board, CCRH, Dr Anil Khurana, Director General In-charge, CCRH; Dr Raj K Manchanda, Director, Directorate of AYUSH, Government of Delhi; Dr S R K Vidyarthi Director, Ministry of AYUSH; and Dr Subhas Singh, Director, National Institute of Homoeopathy, Kolkata. The Council humbly thanks them for their generosity and sparing their valuable time for this event at a short notice
Understanding the role of homoeopathic preparation of Berberis vulgaris in mitigation of sodium oxalate- induced hyperoxaluria: An experimental approach
Background: Hyperoxaluria and calcium oxalate crystal deposition in the kidneys lead to overproduction of reactive oxygen species, resulting in the development of oxidative stress and renal injury. At the cellular levels, mitochondria and NADPH oxidase involved in reactive oxygen species production play a crucial role in the pathogenesis of hyperoxaluria-induced renal injury. Objective: The objective was to investigate the therapeutical effect of homoeopathic drug Berberis vulgaris, a potent antioxidant, upon regulation of NADPH oxidase against acute high-grade sodium oxalate-induced hyperoxaluria in rats. Materials and Methods: Hyperoxaluria was induced in male Wistar rats by administering a single dose of sodium oxalate (70 mg/kg body weight) intraperitoneally, and the treatment groups were pre-treated with homoeopathic drug Berberis vulgaris 6c (20 μl/100 g of body weight) ultra low dose for 7 days. Results: Berberis vulgaris significantly reduces hyperoxaluria-induced oxidative stress and restores antioxidant enzyme activities in kidney tissue. Histological analysis depicted that Berberis vulgaris treatment decreases renal epithelial damage and inflammation and restored normal glomerular morphology. Furthermore, immunoblotting analyses of NADPH oxidase revealed significant increased activity in the renal tissue of hyperoxaluric rats when compared to that of control rats. This has been brought back to normal by Berberis vulgaris treatment. Conclusion: Thus, our results emphasised that the Homoeopathy drug Berberis vulgaris has been effective in ameliorating sodium oxalate-induced acute hyperoxaluria in Wistar rats by modulating mitochondrial oxidative stress through the inhibition of NADPH oxidase
Proposed interaction mechanism between medicine and the diseased cell in diluted homoeopathic medicine
Background: High-diluted homoeopathic medicines practically contain no medicinal molecules. The disease-curing mechanism of homoeopathic medicines has not yet been adequately understood. Acceptable knowledge of this mechanism is essential for further development of homoeopathic science. Objectives: The purpose of this article is to provide a phenomenological model to understand the interaction mechanism between homoeopathic medicines and the diseased cell (DC), which cure diseases with a view to build a conceptual framework that would facilitate subsequent clinical and theoretical investigations. Methods: We have proposed the formation of hydrogen bonded nano and micro clusters (NAM) during the preparation (succession) of homoeopathic medicines. NAM are composed of effective ionic charge (such as O+, H + and other ions) distribution patterns (CDPs). During the electrostatic interaction between CDP around NAM and that around DC, H + ion (proton) or other ion tunnelling takes place, which normalises the highly disordered (higher entropy) state of the CDP around DC to bring it to the normal state. Results: NAM is DC dependent. The entropy change around the DDP leads to information change, which is transmitted to the brain through neurotransmitters to complete the disease remediation process. Proton or ion tunnelling from NAM to DC is quantum mechanical in nature. Conclusion: A novel phenomenological model demonstrating the interaction between DC and homoeopathic medicines (NAM) has been proposed that cures the disease. Ion tunnelling, entropy and related information change (cells signalling) taking place during the healing process appeared to be associated with biological phenomena, yet to be fully developed
Simplify the complexity and replicate the simplicity: Book review of Standard Treatment Guidelines in Homoeopathy
Prevalence of Homoeopathic polar symptoms: A Follow-up pilot study conducted in Mumbai in 2017
Background: Prospective assessment of homoeopathic symptoms is different from eliciting symptoms in daily practice. In prognostic factor research, we apply symptom questionnaires with Likert scales to assess symptoms in different intensities. In former research, we tested a 5-point Likert scale, which rendered a rather high prevalence for some symptoms even the strongest intensity, not useful in daily practice. A longer, 7-point Likert scale might render more useful outcome. Objective: To study if a longer Likert scale perform better in homoeopathic prognostic factor research. Methods: A 7-point Likert scale questionnaire with 30 polar symptoms was tested on 300 patients. Responses to various domains of temperature, climate, diurnal, influence of sleep, eating and desires/aversions were elicited. The outcome was compared with the former 5-point Likert scale. Results: The mean prevalence of all symptoms in the highest intensity with the 7-point Likert scale is (much) lower than in the 5-point scale, and for some symptoms, more useful. For a few symptoms, the prevalence remained high, even in the highest intensity. Conclusion: A longer Likert scale performs better in homoeopathic prognostic factor research, but not for all symptoms. The filling out of this questionnaire by patients should be guided by homoeopathic practitioners who are properly trained in prospective assessment of homoeopathic symptoms
Holistic treatment of chronic myeloid leukaemia with adjuvant homoeopathic therapy: A case report
Introduction: Chronic myeloid leukaemia (CML) is a clonal myeloproliferative disorder of haematopoietic stem cell. Case Summary: This is a case of a 28-year-old female having CML for 1½ years, on regular allopathic medication. The patient was suffering from ulceration in the oral cavity, frequent offensive loose stools with melena and prolonged menstrual cycle with heavy bleeding for 3 weeks. After analysing the constitutional make-up of the patient, Platinum metallicum 200C was prescribed. Over a period of 3 months, the patient reported improvement in weakness, nausea, sleeplessness, irritability, heavy menstruation, loose black stools and backache. Until the last follow-up while submitting this report, the patient was on the maintenance dose of Imatinib along with homoeopathic medication
Homoeopathic drug proving researches (1996–2018): A scoping review
Background: A systematic review on homoeopathic pathogenetic trials (HPTs) from 1945 to 1995 was published in 2007, and the basic question whether the effect produced by homoeopathic drugs in healthy human volunteers is equivalent to placebo or otherwise remained unanswered. There is a need to take up another review of HPTs conducted in the last two decades, to assess the changes in the methodologies adapted and to assess whether the effects produced in apparently healthy volunteers is due to homoeopathic medicines in high dilutions or not. Objective: To seek, collect, review and describe HPTs published during 1996–2018. Materials and Methods: A comprehensive literature search, both electronic and manual, was done using search terms ‘homoeopathic drug proving’ and ‘homoeopathic pathogenetic trial’ with time constraint of 1996–2018 in English language. As per the inclusion and exclusion criteria, the papers were selected for extraction of data in the predefined extraction form. Results: One hundred and forty-seven eligible records (74 peer-reviewed [PR] and 73 non-peer-reviewed [NPR]) of HPTs of 214 drugs were identified and subjected to the extraction of data. Majority of the drug proving records were contributed by the Central Council for Research in Homoeopathy which included 86 records (24 PR and 62 NPR) with the data of 24 and 63 drugs, respectively, and by Riley, one book (NPR) with data of 68 drugs. Heterogeneity was encountered in all aspects – design, conduct, participants and outcome reporting.Conclusion: This preliminary study is the basis for data recovery and for the forthcoming program of systematic review and meta-analysis, which may include the HPTs published in other languages
Homoeopathic treatment of viral warts with Calcarea phosphorica
Introduction: Viral warts are the most common cutaneous infection caused by human papillomavirus. Warts can be treated by many available modalities such as cryotherapy, chemical cauterization, curettage, electrodessication and laser removal. However, most of these therapies can cause scarring. They also cause application-site reaction and recurrence. The homoeopathic literature has a plethora of medicines for the treatment of warts. Case Summary: A 4-year-old girl presented with reappearance of multiple warts on the face after a month of laser treatment. This time, the warts were on the right side of the forehead and one on the right cheek and were persisting for 8 months. The patient responded well to individualised homoeopathic treatment, i.e. Calcarea phosphorica 200 in single dose with complete recovery within 1 month without subsequent relapse. Even though the medicine is mentioned in the fourth grade against the rubric \u27Face – Warts\u27 in the Complete Repertory and is not used commonly in the cases of warts, it acted beneficially. Hence, this case emphasises the importance of individualised homoeopathic treatment based on characteristic general symptoms
Management of post-intubation subglottic stenosis with individualised homoeopathic therapy: A case report
Introduction: Subglottic stenosis is a narrowing of the airway just below the vocal cords. This narrowing can cause serious breathing difficulties. Subglottic stenosis can be congenital or acquired. Frequent or long-term intubation is the most common cause of acquired subglottic stenosis. Case Summary: In this case report, adjuvant homoeopathic treatment helped prevent tracheal stent implantation surgery, otherwise deemed necessary in such a state and improved the overall general state. This case report gives ground to further investigate the extent to which individualised Homoeopathy may be applied in postintubation subglottic stenosis