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Effect of kombucha green tea (Camellia sinensis) on mRNA SREBP-1c expression of dyslipidemic model rats
Get PDFIntroduction: Dyslipidemia is a condition marked by irregularities in the levels of lipids in the blood. The long-term use of synthetic hypolipidemic drugs can lead to numerous side effects, necessitating the search for alternative herbal remedies. Potential benefits of kombucha green tea (KGT), a traditional fermented drink with symbiotic SCOBY culture, known for its hypocholesterolemic, hepatoprotective, and antioxidant effects. These properties contribute to the management of advanced dyslipidemia by enhancing the activation of AMPK, which represses transcription of SREBP-1c involved in coding genes related to de novo lipogenesis in the liver. This study aims to investigate the potential benefits of KGT in Rattus norvegicus dyslipidemia.Methods: The experiment was conducted on five groups of male Rattus norvegicus, including a dyslipidemia control group (DLP), a healthy control group (NC), and the DLP group with KGT intervention at doses of 70, 85, and 100 mg/kg BW. SREBP-1c mRNA expression was analyzed using Real Time-qPCR.Results: Significant decrease in TC, LDL, and TG levels and an increase in HDL between the DLP group and the KGT intervention group (p<0.05). Moreover, SREBP-1c mRNA expression also decreased in all KGT treatment groups compared with the DLP group (p<0.05).Conclusions: Supplementation KGT in this study was shown to reduce the level of mRNA expression of SREBP-1c in the liver and improve serum lipid profile of dyslipidemic rats.
The impact of study abroad on the transformational learning of Chinese international graduate students in Thailand
Get PDFBackground: Educating overseas offers chances for intellectual, cultural, and personal development. With an emphasis on cognitive, emotional, and social transformations, this investigation explores the life-changing educational experiences of Thai graduate students who studied in China.Objective: The project is to investigate how Thai graduate students\u27 creative conceiving, cultural competency, and self-awareness are improved by studying abroad.Methods: Data from 226 Chinese graduate students enrolling at Thai universities was gathered using a quantitative methodology. Key elements of transformative learning, such as social, emotional, and cognitive development, were evaluated through a standardized questionnaire. Using SPSS software, statistical methods including regression analysis, descriptive statistics, and structural equation modeling (SEM) were used to investigate the connection between study abroad experiences and positive effects.Results: According to outcomes, pupils which actively participated in collaborative learning and cultural exchange showed notable academic and personal development. Participants showed increased self-awareness, flexibility, and cultural competency. The advantages of global education were further reinforced by the good effects learning abroad had on students\u27 critical thinking and intercultural comprehension.Conclusion: This investigation emphasizes that studying overseas could result in life-changing educational experiences, especially when it comes to developing analytical and cultural understanding. According to the findings, international education is crucial for improving students\u27 academic and personal growth. Future studies should compare experiences in other cultural contexts and investigate other elements impacting positive educational outcomes
Research on the mechanism of fertility support measures to increase the fertility rate
Get PDFIntroduction:Declining fertility rates present significant challenges to socioeconomic stability and population sustainability worldwide. Fertility support measures, including financial incentives, childcare, and parental leave policies, are crucial yet their effectiveness varies across different socioeconomic and cultural contexts. The aim is to examine the mechanisms of fertility support measures, such as economic, social, and health policies, and determine the effective strategies for increasing fertility rates and promoting family well-being.
Methods:A mixed-methods approach was adopted, combining quantitative information from national fertility trends with qualitative insights collected from interviews and surveys conducted with a target population of 200 individuals. This methodology allows for a comprehensive understanding of the factors influencing fertility decisions.
Results:The findings underscore the importance of aligning fertility policies with broader social and economic frameworks to enhance their effectiveness. Key themes identified include the necessity of integrating fertility support into wider family welfare initiatives, addressing gender equity concerns, and creating a supportive environment for parenting.
Conclusions:This research contributes to understanding targeted interventions aimed at countering fertility decline and offers valuable insights for policymakers seeking sustainable solutions to this global issue. A holistic strategy that encompasses various aspects of family welfare is recommended to increase fertility rates effectively
Mapping and Visualizing the Intersection of Sentiment Analysis and Mental Health
Get PDFIntroduction: Sentiment analysis, a computational approach to evaluating emotions in textual data, has gained significance in mental health research. It assesses public sentiments on mental health issues and aids in early disorder detection through social media and digital platforms.
Objectives: This study aims to analyze the intersection of sentiment analysis and mental health research, identifying key scholarly trends, thematic developments, and global collaborations from 2013 to 2024.
Methods: A bibliometric analysis was conducted using 521 documents from Scopus, including journal articles, book chapters, and conference papers. Biblioshiny, VOSviewer, and CiteSpace were used to analyze publication trends, co-authorship networks, and keyword co-occurrences.
Results: The field has grown at an annual rate of 42.45%, with research output peaking in 2023 (134 articles). Key themes include AI applications in mental health, sentiment-based diagnosis, and the impact of COVID-19. China, the USA, and Australia are the leading contributors, while Bangladesh and Switzerland have the highest citation impact per article. The study maps extensive international research collaborations.
Conclusions: Sentiment analysis is an evolving field with global collaboration. Advances in machine learning and NLP enhance its potential for real-time mental health monitoring and predictive analysis. Future research should focus on personalized AI-driven interventions, ethical considerations, and expanding datasets to improve diagnostic accuracy. This study provides insights for researchers, practitioners, and policymakers in leveraging sentiment analysis for mental health advancements.
Assessment the Properties of Lightweight Self-Compacting Concrete Incorporating Pozzolanic and Waste Materials as Binary and Ternary Blended Binders
Get PDFThe work investigate methodology of creating lightweight self-compacting concrete (LWSCC), with a specific emphasis on utilizing natural and industrial waste materials and theirs effect on the workability and strength properties. The cement replaced with 10%, 20%, and 30% of (limestone powder (LP)), 10%, 20%, and 30% of (calcined kaolin clay (CKC)), and 20% (ground granular blast slag (GGBS)) as substitutes of Portland cement in a binary and ternary mixes. Substitution of 30% CKC decrease slump flow (mm) by 7.5% compared to control mix while the binary mixes of 30% LP and 20% GGBS increased slump flow value by 4.2% and 3.6% respectively compared with control mix. Binary mixes decreased in density at all ages, except the mix of 20% GGBS increase the density by 38 g at 7 days and by 40g at 28 days compared to control mix. Lowest density was observed in binary mixes with 30% CKC and 30% LP by 61g, and 51g respectively compared to control mix. The binary mixtures exhibited an increase in compressive strength over time, with the 20% GGBS mixture demonstrating the most substantial improvements. The 10% CKC mixture demonstrated notable strength improvements, particularly at 7-day. The 20% LP mixture demonstrated robust performance, attaining 50.3MPa after 90 days. The 30% CKC mixture exhibited diminished performance, particularly at initial curing ages. The 10% LP and 30% CKC mixtures did not attain strengths equivalent to those of higher LP and lower CKC blends. The control mixture surpassed all combinations.
Influence of sustainability practices on employee commitment in automobile industry
Get PDFThe objective of the study is to highlight the strategic role of different intangible assets like sustainability practices in driving commitment from workers. The study utilizes Intellectual capital-based view theory to explain the role of sustainability practices in driving organizational cultural values, or long-term relationships among the firm and its stakeholders - customers, allies, and suppliers. The company in general is gaining competitive advantages in being useful to the society where it does business. A survey is used to collect data from automobile industry. This industry is chosen based on their higher carbon foot prints. The results of the survey presented important clues and specific pattern in the first instance. Further structural equation modeling (SEM)-based approach is used to test the relationship between the dependent and independent variables. The results assure the indirect influence of soft practices on employee commitment in the organization. This study provides useful insights into the impact of sustainability practices on the human capital management in the organization. After the data analysis it was concluded that sustainability practices have a mediating effect on employee behavior and they influence the organizational commitment of an employee
The role of state institutions in the formation of security policy during potential military conflicts
Get PDFIntroduction: The role of state institutions in the formation of security policy during potential military conflicts is the key to ensuring global stability and a proactive response to world peace threats. The aim of the article is to analyse the influence of state institutions on international security policy in light of hybrid wars and innovative methods of conflict.Methods: The philosophical approach is aimed at the moral responsibility of the government to its citizens and the justification of the use of force from an ethical point of view. The article demonstrates that adapting state institutions to contemporary challenges, such as cyberthreats and hybrid technologies, contributes to strengthening global security and stability. The analysis is based on using linear regression to forecast the armament of leading countries in the military sphere and potential conflicts in the future.Results: The results obtained through linear regression predict a 20% increase in military industry and an escalation of potential military conflicts.Conclusions: The philosophical significance of the article lies in the study of the fundamental role of state institutions as bearers of the moral authority of adaptive security policy. Further research suggests delving into the philosophical foundations of creating a global security architecture
Examination Of The Functionality Of The ‘Guitar Education And Accompaniment’ Course Delivered In A Virtual Classroom Environment For Instrument Performance
Get PDFObjectiveThis study aimed to determine the technical and musical levels of the students’ instrument performances. In this direction, the functionality of this course was evaluated by determining the technical, musical and general performance levels of the students.
MethodsIn this study, where action research was adopted, two action studies were implemented within the scope of this study. The Performance Observation Form developed by Şenoğlu Özdemir (2019) as two dimensions, technical and musical, was used as the data collection tool. The study was carried out within the scope of the virtual classroom and Zoom application was used. Also, the Musescore, a native Turkish notation writing program, was used to explain musical information and studies. Within the scope of the study,
ResultsThe data obtained from the video recordings of the lessons conducted within the scope of the action research contributed to the management of the process for students’ better understanding of subjects they had difficulty with for the next lesson. It was determined that the fact that each of the students in the study group played a different major instrument affected their performance.
DiscussionSuggestions were made to improve the instrument performance in the ‘Guitar Education and Accompaniment’ lesson delivered in the virtual classroom environment
Whistleblowing Intentions of Accountants and Auditors: Evidence from the Philippines and Indonesia
Get PDFIntroduction: Accountants and auditors are entrusted to maintain high levels of integrity and independence in the practice of their profession. Whistleblowing is a critical aspect on fraud reporting disclosing financial irregularities in the governance and financial management of an institution. The study aims to provide evidence on the internal-external whistleblowing intentions among accountants and auditors in the Philippines and Indonesia, and identify what factors will influence them in reporting the violations they uncover. Methods: The samples tested are accountants/auditors from the Directorate General of Taxes (DJP) of the Ministry of Finance (Kemenkeu) in the DKI Jakarta area and Certified Public Accountants and/or auditors from the Philippines. Quantitative analysis originating from the results of questionnaire data processing were employed in this study. Purposive sampling of sixty-four accountants/auditors of the Directorat General of Taxes in Indonesia and sixty-four practicing accountants/auditors in the Philippines were used in this study.Results: The study shows that attitude and independence commitment have a significant relationship to the internal-external whistleblowing intentions of accountants and auditors in the Philippines. On the other hand, rationalization significantly affects only the external whistleblowing intentions of the Philippine accountants/auditors. Religiosity has no significant correlation to whistleblowing intentions in the Philippines. Attitude, rationalization, and religiosity have a significant impact on the intentions of Indonesians to blow the whistle towards authorities. Independence commitment does not show a significant relationship with external whistleblowing intentions.
A Bibliometric Analysis of Juvenile Crimes and Psychological Well-Being: Trends, Patterns, and Gaps in Research
Get PDFIntroduction: Adolescent criminal behaviour is considered to be a serious global societal concern, with adverse physical and psychological effects for both the victims as well as the perpetrators. According to studies, incarcerated adolescents experience a greater risk of mental illnesses than the overall juvenile population. Approximately 14% to 20% of young individuals in the general population are diagnosed with a mental condition, with 9% to 13% experiencing severe emotional distress. The current study aims to find the patterns of previously existing literature associating Juvenile Crimes and Psychological Well-Being.Methods: After screening the units through a Prisma model, 1068 documentary units were included for further analysis. The documentary units were analysed using VOS Viewer Software and Hazing’s Publish and perish software.Results: From the results it was found that the United States secured the top ranking in terms of the number of papers and citations with over 862 papers and 26544 citations with medicine being the top contributing area. The current study also identified top authors, journals and research papers that were the major contributors in the area. Further bibliometric analysis showed the collaboration between different authors, journals, themes and organizations.Conclusion: The study gives an overall understanding about the various research as well as various aspects with which researchers have studied the current area. The research gap is evident from the number of publications as well as the areas in which the research has been looked into which thereby lays the platform for future studie