Journal of Widya Medika Junior
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CORRELATION OF PHYSICAL ACTIVITY WITH TOTAL CHOLESTEROL RATIO TO HIGH-DENSITY LIPOPROTEIN IN HYPERTENSION ELDERLY AT PUSKESMAS GEDANGAN SIDOARJO
Get PDFBackground: The elderly have a higher risk of developing hypertension. The elderly will experience a decrease in physical activity due to a decrease in stamina and body strength due to aging. This situation can increase the risk of non-communicable diseases such as coronary heart disease (CHD) and affect blood cholesterol levels in the body. Objective: This study aimed to understand the correlation of physical activity intensity with the ratio of total cholesterol to HDL in hypertension elderly at Puskesmas Gedangan Sidoarjo.Methods: This study is an analytic study with the research subjects elderly with hypertension at the Puskesmas Gedangan Sidoarjo with a cross-sectional study design. Using Spearman's correlative test with the Statistical Product and Service Solution (SPSS) program, data analysis was carried out. Results: There is a negative correlation between physical activity and the ratio of total cholesterol to HDL in the elderly with hypertension with p = 0.004 (<0.05) and the correlation value (τ) = -0.424, which indicates a sufficient correlation value. Of 45 respondents, 11 people (24.4%) had low physical activity intensity, 21 people (46.7%) had moderate physical activity intensity, 13 people had (28.9%) heavy physical activity intensity, 29 people (64.4%) had a total cholesterol/HDL ratio ≤ 5, and 16 people (35.6%) had a total cholesterol/HDL ratio >5. Conclusion: There is a negative correlation between physical activity intensity and the ratio of total cholesterol to HDL in the elderly with hypertension at Puskesmas Gedangan Sidoarjo, which means the higher the intensity of physical activity carried out by the hypertensive elderly, the lower the total cholesterol/HDL ratio
ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT OF KITOLOD (Hippobroma longiflora) LEAVES AGAINST STREPTOCOCCUS PYOGENES
Get PDFBackground: Antimicrobial resistance to antibiotics has been emerging as a serious issue in healthcare, hence the need to discover and develop new treatment alternatives. Chemical compunds found in medicinal plants can potentially be used to synthesize new antibiotic agents, one of which is the leaves of kitolod (Hippobroma longiflora). Phytochemical screening of kitolod leaves showed positive results for secondary metabolites presumed to have antibacterial effects. Objectives: The purpose of this study was to examine the antibacterial activity of ethanolic extract of kitolod leaves against Streptococcus pyogenes. Methods: Antibacterial activity of the ethanolic extract of various concentrations (0,25%, 1,75%, 3,25%, 4,75%, 6,25%) were evaluated by broth microdilution method on a 96-well microplate and by streaking on agar plates. Results: Minimium Bactericidal Concentration (MBC) of ethanolic extract of kitolod leaves against Streptococcus pyogenes was 1,75%. Minimum Inhibitory Concentration (MIC) of ethanolic extract of kitolod leaves against Streptococcus pyogenes could not be inferred. Conclusion: Ethanolic extract of kitolod leaves showed antibacterial activities against Streptococcus pyogenes
CORRELATION BETWEEN SOCIAL ACTIVITY LEVEL WITH DEPRESSION IN ELDERLY DURING THE COVID-19 PANDEMIC
Get PDFBackground: With the COVID-19 pandemic that’s currently happening, the Indonesian government made a policy called Pembatasan Sosial Berskala Besar (PSBB) to prevent the transmission of the COVID-19 virus. As a result of this new policy there was a change in the lives of Indonesians, like restrictions and a decrease in their social activities. The elderly are individuals who experiences a decline in various body function, which causes decreased social activities, and due to the reduction of their social activities, they’re potentially to experience depression due to feeling isolated and lonely. With this PSBB policy, the elderly whose social activities have already decreased, will potentially experience a more and massive reduction in their activities, and because of that the potential for depression will likely to increase.Objective: To determine the correlation between social activity level with depression in elderly during the COVID-19 pandemic.METHOD: The design of this research is observational analysis using a cross sectional method. The data were collected using the Australian Community Participation Questionnaire (ACPQ) and Geriatric Depression Scale (GDS). Statistical analysis test used in this research was Spearman correlation test.RESULTS: Social activities of the elderly in the moderate category were 47.2% and elderly who are not depressed were 81,5%. The results from the Spearman test were found to have a significant correlation between the two variables, p value = < 0.05. The correlation level from the test was -0.335 which indicates a low correlation level.CONCLUSION: There is a significant correlation that has a negative value, so it can be concluded that if social activity level is high, then the incidence of depression is low or non-existent. KEYWORD: Elderly, Social Activity, Depression, COVID-19 pandemic, Pembatasan Sosial Berskala Besar (PSBB)
CORRELATION BETWEEN THE NUTRITIONAL STATUS OF PREGNANT WOMEN WITH STUNTING BABIES 6-24 MONTHS OLD IN THE WORKING AREA OF PASREPAN HEALTH CENTER
Get PDFBackground: Stunting is a condition of impaired growth that children experience because of prolonged poor nutrition. Factors that cause stunting are the nutrition status of pre-pregnancy mothers, nutrition status during pregnancy, early initiation of breastfeeding, exclusive breastfeeding, environment sanitation, and infection in children. Stunting has an impact on suboptimal intelligence in children and also can result in a poor immune system. Objective: To know the correlation between pregnant mothers' nutrition status with stunting babies 6-24 months old in the working area of Puskesmas Pasrepan. Method: This study was an observational analytical study with a case-control retrospective design, participated by 80 babies which 40 were stunted and the other 40 were normal height and was taken from Pasrepan Health Center secondary data using consecutive technique sampling. Data was taken from Puskesmas Pasrepan consisted of mid-upper arm circumference (MUAC) of pregnant women, the height of children 6-24 months, age of children, number of ANC visits, and sex of children. Variables were analyzed using Chi-Square to know the correlation between the nutritional status of pregnant women with stunting. Results: 5 out of 6 stunted 6-24 months old babies (83,3%) were from malnourished pregnant women or maternal chronic energy deficiency (CED), and 35 out of 40 stunted 6-24 months old babies (47,3%) were from maternal with normal nutrition. The correlation between the nutritional status of pregnant women with stunting results was (p=0,09). Conclusion: There is no significant correlation between the nutritional status of pregnant women with stunting babies 6-24 months old
THE CORRELATION OF TWO MONTHS FULL OF BREASTFEEDING ON EARLY INITIATED BREASTFEEDING GROUP WITH PUERPERIUM BLEEDING
Get PDFBackground: Postpartum bleeding is one of the main causes of mortality in mothers in 2017. Based on Profil Kesehatan Provinsi Jawa Timur's data in 2017, about 28,26% of mothers' mortality percentage is because of postpartum bleeding. Some of the factors affecting the duration of puerperium bleeding are the initiation of early breastfeeding and exclusive breastfeeding. Early breastfeeding initiation can stimulate the oxytocin hormone to contract the uterine and help complete the extrusion of the placental site and sloughing of decidua tissue (lochia). Objective: This study aims to know the correlation of 2 months full of breastfeeding on early initiated breastfeeding group with puerperium bleeding. Method: This study is an observational analytical study where the design is cohort retrospective, and the 60 samples used in this research are taken with simple random technique sampling. This research was carried out by collecting information from secondary data, and the whole process was done in Gotong Royong Hospital Surabaya from July to September 2020. This research used the Mann-Whitney U test to analyze and find the correlation of both variables. Results: Based on the statistic test, there is no correlation between both variables, resulting in p = 0,211. Conclusion: there is no significant correlation between 2 months full of breastfeeding on the early initiated breastfeeding group with puerperium bleeding
THE EFFECT OF PERORAL POLYVINYL CHLORIDE MICROPLASTIC ON THE VALUE OF PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME IN RATTUS NORVEGICUS WISTAR STRAIN
Get PDFIntroduction: Microplastics can enter the human digestive system as polyvinyl chloride (PVC). Microplastics ingested by humans will accumulate in several organs. Microplastic accumulation in the liver causes inflammation, which damages hepatocyte cells, impairing liver synthesis function, one of which is the synthesis of blood clotting factors.Purpose: The purpose of this study was to determine the effect of oral microplastic polyvinyl chloride on prothrombin time (PT) and activated partial thromboplastin time (APTT) in Rattus norvegicus strain Wistar (APTT).Method: The experimental design incorporated a post-test-only control group. There were 12 rats randomly assigned to the control (K) or experimental (E) groups. For 28 days, Group E was exposed to microplastic type PVC at a concentration of up to 0.5 mg/day in 1 cc of Aquabidest via an oral probe. Blood samples were analyzed using a coagulation analyzer at BBLK Surabaya. The statistical test used an independent t-test.Result: There was a significant difference in the mean PT value of group K (9.8 ± 0.99 seconds) compared to group E (14.23 ± 9 seconds) (p=0.024) and the mean APTT value of group K(18.32 ± 7.96 seconds) compared to group E(26.1 ± 18.15 seconds) (p=0.022).Discussion: These findings confirm the theory that exposure to polyvinyl chloride microplastics in the liver can induce hepatocyte cell inflammation and impair the liver's ability to synthesize blood clotting factors, resulting in prolonged PT and APTT values.Conclusion: Oral administration of PVC microplastic affects PT and APTT values
DEPRESSION RELATIONSHIP WITH BLOOD PRESSURE IN THE ELDERLY AT THE TRESNA WERDHA KHUSNUL KHOTIMAH SOCIAL HOME PEKANBARU IN 2018
Get PDFABSTRACTBackground: Depression is a common mental disorder, characterized by constant sadness and loss of interest in activities that are usually liked, accompanied by an inability to carry out daily activities. Elderly is a group that experiences depression due to physical changes and environmental social conditions. Some other risk factors that can cause depression in the elderly include biological factors, marital status, and psychosocial factors. Biological and psychosocial factors have a relationship with changes in the levels of hormones and neurotransmitters in the body. Changes in hormone levels and neurotransmitters can cause changes in blood pressure. Blood pressure is categorized as normal if the systolic blood pressure is less than 120 mmHg and the diastolic blood pressure is less than 80 mmHg and high blood pressure if the systolic blood pressure is more than 140 mmHg and the diastolic blood pressure is more than 90 mmHg. Objective: To determine the relationship of depression to blood pressure in the elderly at the Tresna Werdha Social Home Khusnul Khotimah Pekanbaru in 2018. Research Methods: The method used in this study is analytic observation with a cross-sectional design. The sampling technique used the total sampling method, where in this study the population was a sample, but after exclusion the number of samples obtained was 41 respondents. Data collection was carried out by observations made by interviewing respondents using questionnaires and blood pressure measurements using a Sphygmomanometer and stethoscope. Results: Obtained p values (Sig.) Systolic blood pressure and diastolic blood pressure showed a number of 0.021 and 0.019. This p (Sig.) Value is small of 0.05, this indicates a significant relationshipof depression to blood pressure in the elderly at the Tresna Werdha Khusnul Social Home Khotimah Pekanbaru in 2018. Conclusion: There is a significant relationship between blood pressure depression in the elderly at PSTW Khusnul Khotimah Pekanbaru in 2018
THE EFFECTIVENESS OF HAEMATOCOCCUS PLUVIALIS EXTRACT ON SUPEROXIDE DISMUATSE LEVEL OF RATTUS NORVEGICUS POST ULTRAVIOLET B EXPOSURE
Get PDFBackground : Exposure of ultraviolet B from the sun can trigger the formation of free radicals, and causing oxidative damage on skin. One of the treatments for skin damage caused by UV B exposure is using 2% glutathione cream. and using green algae Haematococcus pluvialis extract cream.Objective : To analize the differences in the effectiveness of giving Haematococcus pluvialis extract cream and glutathione cream on white rats post ultraviolet B exposure.Method : The type of research used in this study is experimental with the post test only control group design approach. The number of samples was calculated using the Federer formula, with a total sample of 30 white rats that are devided into 6 groups. The parameter is superoxide dismutase enzim that is measured using spectrophotometer.Result : As a normal control group, 5 white rats were not exposed to UV B and were not given any cream while 25 white rats were exposed to UV B light for 2 hours in 14 days, then 5 rats as negative control group were not given any cream, 5 rats as positive control group were given 2% glutathione cream, 5 rats were given 10% Haematococcus pluvialis cream, 5 rats were given 20% Haematococcus pluvialis cream, and 5 rats were given 30% Haematococcus pluvialis cream. The results of this research showed that rats that were given 20% and 30% Haematococcus pluvialis cream has higher superoxide dismutase levels than the other groups.Conclusion : Haematococcus pluvialis extract cream is effective in treating oxidating damage on white rats post ultraviolet B exposure
ANTIBACTERIAL TEST OF SQUEEZED WATER OF KATUK LEAF ON STREPTOCOCCUS PYOGENES
Get PDFBackground: Many infectious diseases still can be found in developing countries, including Indonesia. The common type of infection is upper respiratory tract infection (URTI) in which one of the diseases is pharyngitis. About 5% - 40% of pharyngitis cases are caused by Streptococcus pyogenes. One of the treatments for bacterial infection is antibiotics, but the increasing number of antibiotic resistance causes the need to find other alternatives such as herbal plants for the treatment. The community of Bali, particularly in Singaraja, often consume the squeezed water of Katuk leaf (Sauropus androgynus (L.) Merr) to treat pharyngitis.Objectives: This study aims to determine the antibacterial effect of squeezed water of Katuk leaf on Streptococcus pyogenes by measuring the value of the minimum inhibitory concentration (MIC) and the value of the minimum bactericidal concentration (MBC).Methods: The squeezed water of Katuk leaf was obtained through the squeezing method. The antibacterial activity test used the microdilution method of 96 well plates, then the absorbance value was read using a spectrophotometer to determine the MIC value, and streaking was performed to the blood agar strengthened by the results of the spectrophotometric readings to determine the value of MBC.Results: The results showed that the 300 grams of squeezed water of Katuk leaf had MIC values at a concentration of 10% and MBC values at a concentration of 20%.Conclusion: It can be concluded that the squeezed water of Katuk leaf has an antibacterial effect on Streptococcus pyogenes.Keywords: Antibacterial, Sauropus androgynus (L.) Merr, Streptococcus pyogene
THE CORRELATION OF SERUM ALBUMIN LEVELS AND STAGES OF DECUBITUS IN INPATIENTS AT DR. SOETOMO REGIONAL GENERAL HOSPITAL OF SURABAYA
Get PDFIntroduction : The prevalence of decubitus ulcers in Asia is amounted to 2.7%-16.8%, and in Indonesia, there was a 40% prevalence of decubitus ulcers in 2017. In 2017, the prevalence of decubitus in Bandung was found to be 10.8%. Consequently, the number of active cases and deaths of decubitus ulcers reached 48%. Therefore, efforts to reduce the number of decubitus ulcers are urgently needed, thereby preventing the risk of decubitus severity. Objective: To evaluate the correlation of serum albumin levels and stages of decubitus in inpatients at Dr. Soetomo Regional General Hospital of SurabayaMethod: This research was successfully carried out by means of observational analytics, with a cross-sectional research design. Moreover, this research data were derived from medical record data of inpatients at Dr. Soetomo Regional General Hospital of Surabaya in the period of January 2018 – December 2020, with a total of 144,002 patients. 197 decubitus patients in Pandan I and Pandan Wangi rooms were involved in the sample selection process. Based on the inclusion and exclusion criteria, 57 patients were finally determined as research samples. Samples were selected by utilizing Simple Random Sampling. The number of samples in the case group and control group was amounted to 39 patients, respectively. The data of this research were then analyzed using the Spearman Correlation test.Result: The research results indicated that the least number of decubitus patients at stage I was amounted to 8 people (10.3%), and the highest number of decubitus patients at stage III was amounted to 12 people (15.4%). Furthermore, the results of the Spearman correlation test showed that there was a significant correlation of serum albumin levels and stages of decubitus (p = 0.002).Conclusion: There was a significant correlation of serum albumin levels and stages of decubitus in inpatients at Dr. Soetomo Regional General Hospital of Surabaya in the period of January 2018 – December 2020.Keywords: Albumin, Malnutrition, Stages of Decubitu