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Libro de resúmenes del II Congreso Nacional de Proyectos Fin de Grado de Farmacia
Full text linkDesde la Cátedra Teva y el Grado en Farmacia de la Universidad San Jorge, se convoca el II Congreso Nacional de Proyectos de Fin de Grado en Farmacia. Es un evento académico y científico que reúne a estudiantes, profesores, profesionales y expertos en el campo de la farmacia. Además, en esta edición, se cuenta con la colaboración de la Universidad de Santiago de Compostela, Universidad de Salamanca, Universidad CEU-Cardenal Herrera Valencia, Universidad de Castilla-La Mancha, Universidad Complutense de Madrid, Universidad de Sevilla, Universidad de Murcia y la Universidad de Barcelona
Este encuentro tiene como objetivo proporcionar una reunión para que los estudiantes presenten sus proyectos de fin de grado, compartan conocimientos y experiencias y fomenten la discusión sobre temas relevantes en el campo de la farmacia.
Características del Congreso:
• Presentación de Proyectos: Los estudiantes tienen la oportunidad de presentar los resultados de sus proyectos de fin de grado, destacando la relevancia, metodología, resultados y conclusiones.
• Conferencias y Talleres: Se incluyen conferencias magistrales a cargo de profesionales destacados en el campo farmacéutico, así como talleres prácticos relacionados con la investigación y la práctica farmacéutica.
• Intercambio de Conocimientos: El congreso fomenta el intercambio de conocimientos y la discusión entre estudiantes, profesores y profesionales del sector, promoviendo la colaboración y el networking.
• Reconocimiento Académico: Se otorgan premios y reconocimientos a los proyectos más destacados, fomentando la excelencia académica y la innovación en el campo de la farmacia.
En esta segunda edición se han convocado a todos aquellos estudiantes del grado en Farmacia que hayan defendido su Proyecto o Trabajo Fin de Grado en los cursos académicos 2023-24 o 2024-25 o vayan a defenderlo durante 2024-2025.
Las categorías en las que se puede participar, tanto en modalidad póster como comunicación oral, son:
• Categoría 1. Farmacología, farmacia y tecnología farmacéutica, biotecnología, medicamento individualizado e industria farmacéutica
• Categoría 2. Farmacia asistencial, salud pública, farmacoeconomía, gestión farmacéutica, legislación farmacéutica, historia de la farmacia
• Categoría 3. Biología, inmunología, microbiología, parasitología y farmacognosia
• Categoría 4. Química, alimentos, medio ambiente y técnicas instrumentalesFrom the Cátedra Teva and the Degree Program in Pharmacy at Universidad San Jorge, the II National Congress of Final Degree Projects in Pharmacy is announced. This academic and scientific event brings together students, faculty, professionals, and experts in the field of pharmacy. In this edition, the congress benefits from the collaboration of the University of Santiago de Compostela, University of Salamanca, CEU Cardenal Herrera University (Valencia), University of Castilla-La Mancha, Complutense University of Madrid, University of Seville, University of Murcia, and the University of Barcelona.
The aim of this meeting is to provide a forum for students to present their final degree projects, share knowledge and experiences, and foster discussion on topics of relevance to the field of pharmacy.
Key features of the congress:
• Project presentations: Students will have the opportunity to present the results of their final degree projects, highlighting the relevance, methodology, results, and conclusions.
• Lectures and workshops: The program will include keynote lectures by distinguished professionals in the pharmaceutical field, as well as practical workshops related to research and pharmaceutical practice.
• Knowledge exchange: The congress promotes the exchange of knowledge and discussion among students, faculty, and sector professionals, fostering collaboration and networking.
• Academic recognition: Awards and distinctions will be conferred on the most outstanding projects, promoting academic excellence and innovation in the field of pharmacy.
For this second edition, all students enrolled in the Degree in Pharmacy who have defended their Final Degree Project during the 2023–24 or 2024–25 academic years, or who plan to defend it during 2024–25, are invited to participate.
Categories for participation, either in poster or oral communication format, are as follows:
• Category 1: Pharmacology, pharmacy and pharmaceutical technology, biotechnology, individualized medicines, and the pharmaceutical industry.
• Category 2: Community pharmacy, public health, pharmacoeconomics, pharmaceutical management, pharmaceutical legislation, and the history of pharmacy.
• Category 3: Biology, immunology, microbiology, parasitology, and pharmacognosy.
• Category 4: Chemistry, food science, environment, and instrumental techniques.Cátedra TEV
Medium- and Long-Term Effectiveness of Custom Insoles for Cavus Foot: A Surface Electromyography Study
Full text linkBackground: Cavus foot, defined by an increased medial longitudinal arch and often forefoot plantarflexion, alters biomechanics and increases peak plantar pressures, raising the risk of musculoskeletal disorders such as metatarsalgia, Achilles tendinopathy, and gait instability. Custom foot orthoses are the preferred conservative treatment, offering plantar support, pressure redistribution, and reduction in compensatory muscle activity. This study evaluated the medium- and long-term effectiveness of custom orthoses in 71 patients with cavus feet using surface electromyography (sEMG) and the same shoes. Methods: Muscle activity of the peroneus longus, peroneus brevis, and gastrocnemius was recorded during treadmill gait after one and four months of orthotic use. Results: Significant reductions in muscles were observed, especially after four months, confirming greater long-term effectiveness. No residual benefits were found when participants walked without orthoses. Conclusions: These findings support the clinical value of insoles in reducing the compensatory muscle activity in cavus feet and emphasize the importance of investigating their long-term role in biomechanics and potential pathology risk reduction
Phenolic compounds and epigenetic mechanisms regulating gene expression: effects on human health
Full text linkPhenolic compounds are a large class of phytochemicals with relevant physiological effects that are naturally found in plant-origin foods and derived products. Beneficial effects associated with polyphenol consumption are related to their ability to prevent and/or counteract disease features: they exert anti-inflammatory, antioxidant and anticancer effects, as well as protective actions against metabolic diseases. Phenolic compounds and their metabolites can modulate cell function by regulating gene expression. These effects are partially mediated through specific changes in epigenetic mechanisms such as DNA methylation, histone modifications and microRNA (miRNA) expression. Some polyphenols affect DNA methylation and are effective in counteracting deleterious actions induced by inflammatory/pro-oxidant factors, both in in vitro and in vivo settings. Specific mechanisms include modulation of methyl-transferases, whose levels are inhibited upon polyphenols treatment. Some polyphenols are histone deacetylase inhibitors, which prevent transcriptional repression and suppress tumor and inflammation genes by affecting selective regulation of miRNA expression. Their mostly recognized actions as anti-inflammatory and antioxidants seem to be partially mediated through regulation of individual miRNAs. Due to these actions, polyphenols and polyphenol-derived metabolites are under study in clinical and interventional trials for their benefits on inflammation and/or metabolic disorders. In conclusion, phenolic compounds might be an interesting approach to contribute to human homeostasis given their capacity to dynamically regulate epigenetic factors at cellular and systemic level. The present review aims to study available evidence regarding regulatory effects of polyphenols on gene expression, specifically mediated through epigenetic mechanisms.Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Authors are supported by Ministerio de Ciencia e Innovación, Spain, Gobierno de Aragón and Fundação de Amparo à Pesquisa e Inovação do Espírito Santo (Brazil)
Aprendizaje colaborativo e intercultural con el uso de tecnologías digitales
Full text linkEste estudio analiza cómo las instituciones de educación superior en Iberoamérica están incorporando tecnologías digitales para fomentar prácticas pedagógicas colaborativas e interculturales en los programas de Administración de Empresas y Gestión de Negocios. A través de una metodología cualitativa, se recopilaron datos de diez universidades destacadas en rankings internacionales. Los resultados revelan una creciente integración de herramientas tecnológicas y metodologías como COIL y Global Classroom, así como el compromiso institucional con la formación docente y la internacionalización de la enseñanza. El estudio también identifica desafíos como la brecha digital, la escasez de recursos y la gestión de la inteligencia artificial en entornos educativos. Finalmente, se subraya la importancia de un enfoque estratégico y culturalmente consciente para la incorporación efectiva de las TIC en la educación superior.
This study examines how higher education institutions in Ibero-America are integrating digital technologies to foster collaborative and intercultural pedagogical practices in Business Administration and Management programs. Using a qualitative methodology, data were collected from ten universities listed in international rankings. The findings highlight the increasing adoption of technological tools and methodologies such as COIL and Global Classroom, as well as institutional commitment to faculty training and the internationalization of teaching. The study also identifies key challenges, including the digital divide, limited resources, and the management of artificial intelligence in educational contexts. Ultimately, it emphasizes the need for a strategic and culturally aware approach to the effective integration of ICT in higher education
Transmedia narrative and literacy: an approach to university teaching in the digital age
No full textThis chapter aims to explore the evolution of the use of transmedia narrative in university teaching, with a particular focus on its role in the design of educational strategies adapted to the digital ecosystem. Through a methodological approach based on a scoping review, the objective is to understand how these tools have influenced pedagogical practices in higher education. Transmedia narrative, defined as the creation of stories across multiple platforms and digital formats, emerges as a fundamental resource for fostering student engagement and enriching their learning experience. In parallel, transmedia literacy stands out as an essential competence for both educators and students to interact effectively with digital resources in multimedia educational environments. The importance of transmedia literacy is highlighted as a foundation for the development of teaching strategies that integrate Information and Communication Technologies (ICT). This approach enables the design of interactive, inclusive, and cross-platform educational environments, aligned with the needs and challenges of teaching in the digital context and in response to contemporary demands
Impacto de un programa de rehabilitación cardiaca integral durante el proceso de quimioterapia para contrarrestar los efectos cardio tóxicos en mujeres con Cáncer de Mama- Ensayo clínico controlado y aleatorizado
No full textIntroducción: El Cáncer de mama es la neoplasia más frecuente en mujeres a nivel mundial y su tratamiento con quimioterapia, aunque efectivo, está asociada a efectos secundarios significativos, entre ellos la cardiotoxicidad. Dado que esta complicación puede comprometer la función cardiaca y la calidad de vida de las pacientes, surge la necesidad de implementar estrategias preventivas desde las primeras fases del tratamiento.
Objetivo: Evaluar el impacto de un programa integral de rehabilitación cardiaca que incluye ejercicio aeróbico, entrenamiento de fuerza y educación terapéutica en la preservación de la fracción de eyección del ventrículo izquierdo (FEVI) durante el tratamiento quimioterapéutico en mujeres con Cáncer de mama, comparando con la atención convencional basada en actividad física general.
Metodología: Ensayo clínico aleatorizado, controlado y de doble ciego, con una muestra de 22 mujeres diagnosticadas con Cáncer de mama y en tratamiento con antraciclinas o trastuzumab. Las participantes serán asignadas a un grupo experimental (rehabilitación cardiaca integral) o a un grupo control (actividad física convencional). Se evaluarán variable primaria (FEVI) y segundarias (capacidad funcional, VO2max, fuerza muscular, calidad de vida, ansiedad y depresión) mediante instrumentos validados. El análisis estadístico incluirá Shapiro Willk, test t de Student, ANCOVA y ANOVA, con un nivel de significación de p<0,05.
Resultados esperados: Se espera que el grupo experimental mantenga mejor la función cardiaca (FEVI), con mejoras significativas en la capacidad funcional, fuerza muscular, y estado psicológico en comparación con el grupo control, indicando un efecto protector del programa.
Conclusión: Si se confirma la hipótesis, este estudio reforzara la necesidad de integrar programas estructurados de rehabilitación cardiaca en el tratamiento oncológico desde sus fases iniciales para reducir la morbilidad asociada y mejorar la recuperación global a largo plazo
Gait-Based Screening for Cognitive Impairment in Older Adults: A Fast and Objective Approach
No full textBackground/Objectives: Cognitive impairment in older adults is a growing public health concern due to global population aging. Early detection is crucial, yet current screening methods are time-consuming and require clinical expertise. Gait analysis has emerged as a promising alternative for cognitive screening. The aim of the study was to identify gait variables associated with cognitive impairment and to develop predictive algorithms capable of distinguishing between cognitively impaired and non-impaired older adults using gold-standard gait analysis. Methods: A cross-sectional study was conducted with 42 adults aged > 60 years. Cognitive function was assessed using the Mini-Mental State
Examination (MMSE), and participants were divided into high (MMSE > 24) and low (MMSE ≤ 24) cognitive function groups. Spatiotemporal gait parameters were recorded at participants’ usual pace using the Optogait system. Logistic regression models were developed using half of the sample (training group) and validated in the remaining participants (verification group). Results: Algorithms based on stride length and double support time demonstrated high classification performance. In the training group, the best-performing model achieved an AUC-ROC of 0.91, with a sensitivity of 71.4% and specificity of 92.3%. Validation in the verification group yielded an AUC-ROC of 0.84 and accuracy of 81.0%. Alternative models showed acceptable to excellent predictive power. Conclusions: Gait analysis using gold-standard methods can effectively identify cognitive impairment in older adults. The developed algorithms offer a rapid, objective, and accurate screening alternative with strong potential for clinical application
Needs analysis in an English for medical purposes course
No full textEl objetivo de este artículo es informar sobre un Análisis de Necesidades desarrollado e implementado en un curso de inglés para fines médicos, para investigar las necesidades del alumnado. Actualmente, el análisis de necesidades considera las necesidades y preferencias del alumnado de gran relevancia en el proceso de diseño curricular. El diseño del cuestionario es explicado, con preguntas que abordan las necesidades actuales del estudiantado, las necesidades definidas por el alumnado, y las necesidades subjetivas. A continuación, se presentan y analizan los resultados del cuestionario. Las necesidades actuales se centran en sus destrezas de expresión oral y escrita, mientras que las necesidades objetivo en la comunicación, expresión oral y lectura. Además, sus necesidades subjetivas incluyen la práctica de conversaciones doctor-paciente o la adquisición de vocabulario médico. Por último, cabe destacar que el análisis de necesidades es un proceso dinámico que responde a las necesidades cambiantes de los alumnos.
The objective of this article is to inform about a Needs Analysis developed and conducted in an English for Medical Purposes course, with the aim of investigating learners’ needs and preferences in order to improve course design. A report on needs analysis research is offered to explain the current view that considers learners’ needs of extreme relevance in the process of syllabus design. The design of the questionnaire is explained, with questions addressing learners’ present needs, learner-defined target needs and subjective needs. Then, the results of the survey are analysed and presented. Learners’ present needs concentrate on their speaking and writing skills, while their target needs focus on communication, speaking and reading skills. Moreover, their subjective needs include, among others, the practice of doctor-patient conversations or the acquisition of medical vocabulary. Finally, it should be stressed that needs analysis is a dynamic process, responding to learners’ changing needs
Effectiveness of physiotherapy techniques on depressive symptoms in older adults: a systematic review
No full textIntroduction: The older adult population suffers from a high prevalence of depression, representing an increasing burden on healthcare systems. In this context, this systematic review evaluated the effectiveness of physiotherapy for the management of depressive symptoms in this population. The population aged 65 and over is increasing in developed countries such as Spain, currently accounting for 19.09% and projected to reach 25.2% within the next decade. Depression is one of the most prevalent mental health conditions in this group, affecting 5% of community-dwelling individuals and 25% in institutional settings, significantly reducing quality of life and increasing the risk of dementia. While the pharmacological and psychotherapeutic treatments are standard, they present adverse effects and limitations in this population, prompting the exploration of physiotherapy as a non-pharmacological alternative.
Objective: To analyze the scientific evidence regarding the effectiveness of combining conventional treatments with physiotherapy techniques for symptomatic improvement in older patients with depression, and to identify the most effective physiotherapy technique, when combined with conventional treatment, for depressive symptoms in older adults.
Methods: We conducted a systematic review following PRISMA guidelines, and we performed searches in PubMed, Web of Science (WOS), Scopus and Cochrane Library databases. Study quality and risk of bias were assessed using the Cochrane Collaboration’s tool.
Results: Eight randomized controlled trials, encompassing a total of 1,368 older participants diagnosed with depression or depressive symptoms who received physiotherapy, were included. The findings indicate that physiotherapy techniques, particularly therapeutic exercise, in combination with conventional treatments, may improve depressive symptoms in this population.
Conclusion: Although we observed positive trends in the effectiveness of physiotherapy for depression in older adults, further research is required to validate its clinical efficacy and inform evidence-based treatment guidelines.
Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251079161
Pablo Bellosta López, Jorge Alegre-Ayala, Julia Blasco-Abadía, Víctor Doménech-García
No full textLa infografía muestra los resultados de un estudio transversal sobre la relación entre la actividad física (AF) y la participación en las actividades cotidianas en personas que han tenido un ictus leve en España.
En este estudio transversal, en el que colaboraron varios centros de rehabilitación de España, participaron un total de 130 supervivientes de un ictus leve (61,3 ± 12,4 años, 35 % mujeres) con capacidad para caminar conservada y sin deterioro cognitivo ni de la comunicación. Los niveles de AF fueron autoinformados mediante el Cuestionario Internacional de Actividad Física - versión corta (IPAQ-SF). Las medidas objetivas de AF se monitorizaron con la pulsera Fitbit Inspire 2, que registró el promedio de pasos/día y kilocalorías/día. Los niveles de participación y satisfacción con las actividades se midieron con el Cuestionario de Satisfacción con las Ocupaciones Diarias-Equilibrio Ocupacional (SDO-OB) y la retención de la participación mediante la Clasificación de Tarjetas de Actividades (ACS).
Los resultados de este estudio indicaron que la puntuación total de la ACS mostró una correlación débil con la AF autodeclarada (rho = 0,324) y correlaciones moderadas con las kilocalorías diarias y los pasos medios diarios (rho ≥ 0,581), mientras que se encontraron correlaciones más fuertes para el subdominio de la ACS de actividades instrumentales (rho ≥ 0,640) en comparación con los subdominios de actividades de ocio y participación social (rho ≤ 0,454). La participación en SDO-OB mostró correlaciones moderadas con las kilocalorías/día y los pasos medios/día (rho = ≥ 0,647), y una correlación débil con la AF autoinformada (rho = 0,303). Se encontraron correlaciones más débiles para la satisfacción con SDO-OB con medidas objetivas de AF (rho = 0,407) y la AF autoinformada (rho = 0,254). Las relaciones entre las variables se exploraron calculando los coeficientes de correlación de Spearman.
Las medidas objetivas y autodeclaradas de AF en supervivientes de ictus leve tienen una relación bilateral con sus niveles actuales de participación y las actividades instrumentales de la vida diaria que conservan. Sin embargo, las correlaciones más débiles con el ocio y la participación social pueden sugerir que promover la AF por sí sola, sin integrarla en las actividades diarias relevantes para los supervivientes de ictus, puede ser insuficiente para alcanzar objetivos integrales durante los programas de rehabilitación.
Para más información sobre el estudio de investigación:
de Diego-Alonso C, Alegre-Ayala J, Blasco-Abadía J, Doménech-García V; Part&Sed-Stroke collaborators’; Bellosta-López P. Associations between objective and self-perceived physical activity and participation in everyday activities in mild stroke survivors. PLoS One. 2025 Apr 1;20(4):e0321047. doi: 10.1371/journal.pone.0321047. PMID: 40168391; PMCID: PMC11960890.
Artículo disponible en: https://doi.org/10.1371/journal.pone.0321047
https://repositorio.usj.es/handle/20.500.14888/173