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Bilaterally parallel elliptic flap versus Karydakis flap in primary pilonidal sinus disease: a randomized controlled trial
Get PDFPurposePilonidal sinus disease is a disease that especially affects the young population and causes loss of workforce. Although many treatment methods have been defined, there is still no "gold standard" treatment method. Our objective was to evaluate the postoperative results of bilateral parallel elliptical flap and Karydakis flap in the surgical treatment of pilonidal sinus.MethodsThis study was conducted at the Colorectal Surgery Department of Ankara Numune Training and Research Hospital. It designed a prospective randomized controlled study. Patients that underwent surgery due to pilonidal sinus were included in the study. The patients were randomly divided into two groups. Surgery was performed with the bilateral parallel elliptical flap (BPEF) technique in one group and the Karydakis flap (KF) technique in the other group. Postoperative pain, length of hospital stay, wound complications, time taken to return to work/school, and recurrence incidence were evaluated.ResultsA total of 102 patients were included in the study, 49 in the BPEF group and 53 in the KF group. The length of hospital stay was similar in the BPEF and KF groups (1.41 & PLUSMN; 0.81 and 1.45 & PLUSMN; 0.84, respectively; p > 0.05). There was less postoperative pain in the BPEF group (2.47 & PLUSMN; 1.02 vs 3.57 & PLUSMN; 1.10, p 0.05).ConclusionsThe patients who underwent surgery with the bilateral parallel elliptical flap technique had less pain and a shorter time to return to work/school after the operation. The postoperative complication and recurrence rates were similar in both groups
The MT2 Receptor-Mediated Therapeutic Effects of Melatonin in In-Vivo and Ex-Vivo Rat Models of Migraine
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Association Between Serum Irisin Levels and ST-Segment Elevation Myocardial Infarction
Get PDFBackground: An acute ST-elevation myocardial infarction (STEMI) is a serious cardiovascular condition with a high risk of morbidity and mortality. Irisin is adipomyokine that is associated with various health conditions. In post-STEMI, elevated serum irisin levels are associated with more adverse cardiovascular events.Objective: The purpose of this study was to investigate associations between the serum irisin levels and acute MI (AMI) and whether irisin may be a useful biomarker for severity of AMI in patients with STEMI. Possible correlations between serum irisin and cardiac troponin-I (cTi) levels were investigated.Methods: A total of 90 subjects (46 control subjects and 44 STEMI patients) were included in the study. Besides demographic data, presence of diabetes mellitus and hypertension, electrocardiography (ECG) findings, blood biochemistry, cardiac biomarkers (cTi) and serum irisin levels were examined.Results: Significantly lower heart rate (HR) and significantly higher ST-elevation and QTc interval were detected in ECG recordings in STEMI patients (p < 0.05). Serum irisin levels were significantly lower in STEMI patients compared to the control subjects (p < 0.001). The decrease in the serum irisin levels was significantly correlated with the increase in cTi levels, as well as increased QTc (p < 0.05). The sensitivity and specificity of irisin were found to be 93% and 78%, respectively.Conclusion: Decreased irisin levels were found to be highly predictive in STEMI. In patients with STEMI, the serum irisin levels were associated with cTi levels and QTc, suggesting that irisin is a promising biomarker for AMI cases
Prenatal Parental Emotion Regulation Difficulties and Infants' Communication Skills: The Moderating Role of Infants' 5-HTTLPR Polymorphism and Gender
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Babaların Dil ve Konuşma Bozukluklarına Yönelik Bilgi Düzeylerinin İncelenmesi
No full textBabalar, çocukların dil ve konuşma gelişimlerinde önemli rol oynamaktadır. Babaların, çocukların dil ve konuşma gelişimlerine etkisi bu derece büyük iken babaların çocuklarının dil ve konuşma güçlüğü yaşayıp yaşamadığını anlamalarına yönelik herhangi bir araştırmaya rastlanmamıştır. Bu önem kapsamında, babaların dil ve konuşma bozuklukları hakkında bilgi düzeylerinin ve tutumlarının incelenmesi amaçlanmıştır.Although fathers have an important role in the speech and language development of
children, it has been observed that fathers’ knowledge levels about language and speech disorders are
not sufficient. It is thought that the reason why fathers who received therapy from a speech and language
therapist did not make a significant difference compared to fathers who did not receive therapy is
related to the low participation of fathers in therapy processes. For this reason, it is thought that fathers’
knowledge levels and awareness about speech and language therapy should be increased. It is thought
that this research can be conducted again with more participants
The number of codes over rings of order containing a hull of given type
Get PDFWe study the hull, that is the intersection of a code with its orthogonal, of both linear and additive codes over the rings with unity of order 4, where the orthogonal is the Euclidean orthogonal for linear codes and for additive codes it is determined using characters. We relate the hull of the code with the hull of its image under the corresponding Gray map and use this to count the number of codes with a given hull for additive codes for the rings with characteristic 2. We investigate the codes over these rings which have a hull of given type which gives the cardinality of the hull
Factors of Affecting the Success of Intragastric Balloon
No full textBackground: Our aim was to determine the efficacy and safety of intragastric balloon (IGB) application and the factors affecting its success by evaluating the results of patients who underwent IGB.
Materials and Methods: A total of 277 consecutive patients that underwent IGB between January 2019-September 2020 in our clinic were evaluated. Patients' demographic data, height and weight before the IGB procedure, weight at 6 and 12 months after the procedure, follow-up period, complication status, and whether they received dietician's assistance during the follow-up were recorded.
Results: In 5 (1.8%) patients, IGB was removed for various reasons before the standard period of 6 months. The mean age of the patients was 35.6 +/- 9.5 years, the mean baseline weight and body mass index (BMI) was 92.6 +/- 14 kg and 33.5 +/- 5.4 kg/m 2 respectively. The mean follow-up time was 13 +/- 4.9 months, whereas in 146(53.6%) patients the follow-up was >= 12 months. In the 6-month follow-up, the mean %excess weight loss and %body weight loss were 65.65 +/- 25.19% and 14.69 +/- 6.96%, respectively, whereas at the 12-month follow-up they were 32.38 +/- 24.79% and 6.56 +/- 5.31%, respectively. High BMI (odds ratio = 1.2, 95% CI = 1.0-1.2) and not receiving dietitian's assistance (odds ratio= 8.5, 95% CI = 3.1-23.7) were independent risk factors for unsuccessful IGB application at both 6-month and 12-month follow-ups.
Conclusion: IGB application is a relatively effective and safe weight loss treatment for overweight and obese individuals. High BMI and not getting help from a dietician are risk factors for failure of IGB. To increase compliance with dieticians and therefore success of IGB application, patients should undergo psychiatric evaluation before IGB procedure, and receive psychiatric support, if necessary
Öğretmenlerde ses yorgunluğunun değerlendirilmesi = Assessment of vocal fatigune in teachers
No full textBu çalışmanın amacı, seslerine iş hayatlarında yoğun gereklilik duyan profesyonel ses kullanıcılarından öğretmenlerin ses yorgunluklarının dinlenme/tatil dönemi etkisini incelemektir. Bu çalışmaya farklı branşlarda görev yapmakta olan 23 ile 56 yaş arasında toplam 61 öğretmen katıldı ve katılımcılar geçerliliği ve güvenilirliği yapılmış olan "Ses Yorgunluğu Ölçeği (SYÖ)" ile değerlendirildi. Bu değerlendirme çalışma dönemi sonunda ve dinlenme dönemi sonunda iki kez gerçekleştirildi. Elde edilen veriler dinlenmenin ses yorgunluğu üzerine etkisini görmek için analiz edildi. Ses Yorgunluğu Ölçeğinin ilk iki ana başlığı olan "Yorulma ve Kaçınma" ile "Fiziksel Rahatsızlık" boyutlarında istatistiksel olarak anlamlı fark bulundu (p0,05). Elde edilen bulgular dinlenmenin öğretmenlerin ses yorgunluğu üzerine olumlu etkisini göstermektedir. İlk iki ana başlıkta anlamlı farklılık olup "Dinlenme ile İyileşme" boyutunda anlamlı farklılık olmayışı öğretmenlerin farkındalık içinde olmadığını ve ses sağlıklarını korumaları için bilgilendirilmelerin olması gerektiğini düşündürmüştür.The aim of this study is to examine the changes in the vocal fatigue of teachers, who are professional voice users with intense requirements for their voices in their professional lives, in relation to the impact of rest-vacation periods. A total of 61 teachers, aged between 23 and 56, working in different fields, participated in this study. Participants were evaluated using the Vocal Fatigue Index (VFI), a valid and reliable self-report tool. This evaluation took place twice, at the end of the work period and at the end of the rest period. The data obtained were analyzed to observe the effect of rest on vocal fatigue. There was a significant difference in the dimensions of Fatigue and Avoidance with Physical Discomfort (p<0.05), which are the first two main headings of the VFI. However, there was no significant difference in the dimension of Rest and Recovery, the other main heading. The findings indicate a positive impact of rest on teachers' vocal fatigue. The significant differences in the first two main headings, with no significant difference in the dimension of Rest and Recovery, led to the interpretation that teachers may not be aware. This underscores the importance of informing teachers to protect their vocal health
4-6 yaş arası konuşma sesi bozukluğu olan ve olmayan çocukların semantik akıcılık becerilerinin değerlendirilmesi = Evaluation of the semantic fluence skills of children between 4-6 years of age with and without speech sound disorder
No full textBu çalışma konuşma sesi bozukluğunun olması ve olmaması açısından çocuklarda akıcılık değişimi görmek ve bunu değerlendirmek amacıyla yapılmıştır. 4-6 yaş arası normal dil ve konuşma gelişimi olan 15 çocuk ile yine 4-6 yaş arası konuşma sesi bozukluğu olan 14 çocukla TEDİL testiyle normal gelişimi olan çocukların seviyesi ve Semantik akıcılık testiyle tüm çocukların semantik akıcılık becerileri test edildi. Bu testte ek engel olan çocuklar ve normal dil gelişim sürecine dahil olmayan çocuklar dışlama kriterinden sayıldı ve test yapılmadı. Test sessiz, iyi ışıklandırılmış ve dikkat çeldirici olmayacak şekilde dizayn edilmiş bir ortamda yapıldı. Sonuçlar yazısal olarak kayıt ve transkript edildi. Araştırmanın sonuçları normal ve KSB gruplarının cinsiyet ve yaş özelliklerinin istatistiksel olarak anlamlı farklılık göstermediğini gösterdi. Semantik akıcılık testleri, hayvanlar kategorisi için başarılı performans puanının diğer kategorilerden önemli ölçüde farklılaştığını, ancak diğer kategorilerde olmadığını ortaya koydu. Meyve, sebze ve giyim kategorilerinde de bazı farklılıklar bulunurken vücut organları veya taşıt kategorilerinde farklılık görülmedi. Bu sonuçlar anlamsal akıcılığın belirli alt kategorilerinde performansta farklılıklar olduğunu göstermektedir. Çalışma iki grubun yaşını ve cinsiyetini ilk kez karşılaştırdığında kayda değer bir farklılık bulamadı. Tipik gelişen çocuklar, anlamsal akıcılık testlerinin hayvan ve meyve-sebze kategorilerinde KSB'li çocuklara göre daha iyi performans gösterdi ancak vücut parçaları, taşıtlar ve kıyafet kategorilerinde istatistiksel olarak anlamlı bir fark bulunamadı. Bu, dil gelişiminin çeşitliliğini kavramak için kategori bazlı değerlendirmelerin ne kadar önemli olduğunu vurgulamaktadır. Anahtar kelimeler: Konuşma sesi bozukluğu, Semantik akıcılık, Kategorizasyon, Dil GelişimiThis study aimed to assess speech sound distortion and fluency alterations concerning semantic fluency in children. The research involved 15 typically developing children aged 4-6 and 14 children with speech sound disorders in the same age range. The TEDIL and Semantic Fluency tests were administered. Children with additional disabilities or atypical language development were excluded. Controlled conditions ensured accurate test administration, and outcomes were documented and transcribed. Gender and age did not significantly differ between the typically developing and speech sound disorder groups. Semantic fluency tests indicated a notable difference in successful performance scores specifically in the animal category compared to other categories. Differences were observed in certain subcategories of fruits, vegetables, and clothing, while no distinctions were found in body organs or illness-related categories. The comparison between age and gender in both groups revealed no significant distinctions. Typically, children outperformed those with speech sound disorders in animal and fruit-vegetable semantic fluency categories, highlighting the significance of categorically assessing language development diversity Keywords: Speech sound disorders, Semantic fluent, Categorization, Language developmen
Türkçe konuşan bireylerde serebellar lezyonların dil üzerine etkisi = The effect of cerebellar lesions on language in turkish speakers
No full textSerebellum, beyin hacminin yaklaşık %10'u kadardır ve dikkat, dil, emosyon ve kognitif fonksiyonlardan sorumludur. Serebellum lezyonu sonrası hasarın yeri ve şiddetine göre bireylerde linguistik işlemleme güçlükleri ve kognitif bozukluklar görülebilmektedir. Bu araştırmanın amacı, serebellar lezyonlu bireylerin sağlıklı kontrol grubuna göre linguistik ve kognitif becerilerindeki farklılıklarını saptamaktır. Bu amaç doğrultusunda Afazi Dil Değerlendirme Testi (ADD), Kaza Kompozisyon Resmi, Çizgi Yönü Belirleme Testi, Yüz Tanıma Testi, Harf Silme Testi uygulanmış, elde edilen veriler SPSS (25. Versiyon) programında Mann Whitney U testi ile karşılaştırılmıştır. Serebellar lezyonlu bireyler, ADD'nin total puanı ve tüm alt testlerinde düşük performans göstermişlerdir. Anlatı örneklerinde çaba, sözce arası duraksama, basit cümle üretimi, tereddüt ifadeleri, doldurucu ifadeleri ve anomik örüntüleri daha yüksek sıklıkta ürettikleri görülmüştür. Sözel olmayan kognitif becerilerde (Harf Silme Testi, Yüz Tanıma Testi, Çizgi Yönü Belirleme Testi) sağlıklı kontrol grubuna göre anlamlı ölçüde bozulma tespit edilmiştir. Serebellar lezyonların, afazi tanısı olmaksızın formal dil değerlendirmelerine yansıyan linguistik tutulumlara neden olduğu saptanmıştır. Serebellum hasarı olan bireylerin sözel üretimleri sırasında sentaktik karmaşıklığın azaldığı ve konuşma sürekliliğini bozan akıcısızlık davranışlarının artmış olduğu gözlenmiştir. yürütücü işlevlerinde zayıflık olduğu tespit edilmiştir. Sonuç olarak serebellar lezyonlu bireylerin dil, konuşma ve yürütücü işlevlerinin değerlendirilmesi gerekliliği ön plana çıkmaktadır.The cerebellum is approximately 10% of the brain volume and is responsible for attention, language, emotion and cognitive functions. Linguistic processing difficulties and cognitive impairments may be observed in individuals after cerebellum lesion depending on the location and severity of the damage. The aim of this study was to determine the differences in linguistic and cognitive skills of individuals with cerebellar lesions compared to healthy control group. For this purpose, ADD, Accident Composition Picture, Line Direction Identification Test, Face Recognition Test, Letter Deletion Test were applied and the data obtained were compared with Mann Whitney U test in SPSS (25th version) program. Individuals with cerebellar lesions performed poorly on the total score and all subtests of ADD. They were found to produce higher frequencies of effort, inter-verbal pauses, simple sentence production, hesitation expressions, filler expressions and anomic patterns in narrative examples. Significant impairment was found in non-verbal cognitive skills (Letter Erasure Test, Face Recognition Test, Line Orientation Test) compared to the healthy control group. Cerebellar lesions have been found to cause linguistic involvement reflected in formal language assessments without a diagnosis of aphasia. It was observed that individuals with cerebellar lesions had decreased syntactic complexity during verbal production and increased disfluency behaviors that disrupted speech continuity. weakness in executive functions. As a result, it is necessary to evaluate the language, speech and executive functions of individuals with cerebellar lesions