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Nar Kabuğunun Sağlığı Geliştirici ve Hastalık Önleyici Aktivitesi
Get PDFNar kabuğu, potansiyel sağlık yararları ile birlikte güçlü antioksidan aktivite içerir. Nar kabuğunun, polifenol bakımından zengin olması nedeniyle antikanser
potansiyelinin araştırıldığı çalışmalar mevcuttur. Nar kabuğunun, in vitro, in vivo ve klinik deneylerde farklı kanser hücre dizileri üzerinde antiproliferatif
etkiler göstermiştir. Bu derlemenin amacı nar kabuğunun çeşitli kanser hastalıklarına karşı fonksiyonel özelliklerini ve tıbbi faydalarını değerlendirmektir. Ek
olarak, nar kabuğunun in vitro ve in vivo insan ve hayvan klinik deneylerinde kullanımının çeşitli sağlık sorunları üzerine etkisine de yer verilmiştir. Mevcut
veriler, Punica granatum (nar) kabuğunun bazı hastalık durumlarının gelişmesinde engelleyici ve potansiyel terapötik olarak kullanılabileceğini ve insan
sağlığına fayda sağladığını göstermektedir. Bu derlemede nar kabuğunun potansiyel sağlık yararları, geleneksel tıbbi tedavide kullanımı ve kanser ilerlemesini engelleme mekanizması vurgulanmıştır.Pomegranate peel contains powerful antioxidant activity along with potential health benefits. There are studies investigating the anticancer potential of
pomegranate peel because it is rich in polyphenols. Pomegranate peel has shown antiproliferative effects on different cancer cell lines in in vitro, in vivo
and clinical trials. The purpose of this review is to evaluate the functional properties and medicinal benefits of pomegranate peel against various cancer
diseases. In addition, the effects of the use of pomegranate peel in in vitro and in vivo human and animal clinical trials on various health problems are also
included. Available data indicate that Punica granatum (pomegranate) peel can be used as an inhibitory and potential therapeutic in the development of
some disease conditions and benefits human health. This review highlights the potential health benefits of pomegranate peel, its use in traditional medical
therapy, and its mechanism of inhibiting cancer progression
Immediate effects of Kinesio taping on pain, proprioception, and posture in round shoulder individuals with subacromial impingement syndrome: A randomized, double-blinded controlled trial
Get PDFBackground: Round shoulder posture (RSP), characterized by forward shoulder positioning from weakened and tense muscles, disrupts normal biomechanics and can cause Subacromial impingement syndrome (SIS), resulting in pain during specific movements or positions. This study examines the immediate effects of Kinesio taping (KT) on pain, proprioception, and posture in individuals in round shoulder individuals with SIS. Methods: The study involved 114 patients diagnosed with RSP and SIS. Pain intensity was assessed using a Visual Analog Scale (VAS), proprioception was measured with an inclinometer, and posture was evaluated using The New York Posture Rating Chart (NYPRC). Participants were randomly assigned to experimental group (EG) (n = 57), which received KT application, or to sham group (SG) (n = 57), which underwent a sham procedure. KT was applied to the affected shoulder and scapular regions. Assessments were conducted both before and after the application of Kinesio tape. Results: According to the study results, the differences in VAS scores (P = .002), proprioception abduction (P = .023) and NYPRC scores (P = .04), were statistically significant in the EG compared to the SG (P .05). Conclusion: KT demonstrates immediate benefits in reducing pain and improving scapular alignment in individuals with RSP and chronic shoulder pain. These findings underscore its potential effectiveness as a therapeutic intervention for managing symptoms associated with RSP and impingement syndrome, particularly in terms of pain relief and posture enhancement
20-30 yaş arası sağlıklı yetişkinlerde fabl ile elde edilen anlatı örneklerinin analizi: Pilot çalışma = Analysis of narrative examples obtained through fables in healthy adults aged 20-30: Pilot study
No full textFabllar toplumun benimsediği ya da karşı çıktığı davranış ve düşünceleri konu alan edebi bir türdür. Dilin yapısal temeli olan sentaks, konuşmacının düşünceleri ve duygularını, açık ve kesin bir şekilde ifade etmesi için sözcükleri cümleler içinde dizmek olarak tanımlanmaktadır. Eleştirel düşünme ise, problemlerin ortaya konması, problem durumundaki değişimleri ayırt edebilme ve denetleyebilme gibi bazı zihinsel süreçleri kapsamaktadır. Konuşma içeriğindeki bilişsel yükü artışı sentaktik karmaşıklığın artmasına neden olmaktadır. Çeşitli araştırmalarda fablların anlatımı ve fabllarla ilgili eleştirel düşünme sorularının dildeki sentaktik karmaşıklığı ortaya çıkardığı bulunmuştur. Literatürde çocukluk çağı ve adölesan dönemde fabllar yoluyla eleştirel düşünme sorularına verilen cevapların içerdiği sentaktik karmaşıklık düzeyi ile ilgili araştırmalar bulunmasına rağmen genç yetişkinlerle ilgili yeterli veri bulunmamaktadır. Bu araştırmada 20-30 yaş arası primer nörolojik/psikiyatrik hastalık tanısı olmayan sağlıklı bireylerin fablla elde edilen anlatı örneklerinde eleştirel düşünme ve konuşma dilindeki sentaktik karmaşıklıkları incelenmiştir. Çalışmadan elde edilen verilerin, 20-30 yaş arası edinilmiş beyin hasarı olan bireylerin dil ve kritik düşünme becerilerinin klinik ortamlarda değerlendirilebilmesi için değerlendirme aracı geliştirme ve normatif veri tabanı oluşturma amacıyla kullanılması planlanmıştır. 20-30 yaş arasında olan katılımcılara önce Addenbrook Kognitif Değerlendirme Bataryası uygulanmış ve 89 puan üstü alan 33 kişi çalışmaya dahil edilmiştir. Çalışma katılımcılarına fabl okutularak fablı anlatmaları istenmiş ve fabla ilişkin sorular yöneltilmiştir. Fablın anlatısı ile eleştirel düşünme sorularına verilen cevaplar çevrim yazıya dönüştürülmüştür. Transkripsiyonlar ortalama sözce uzunluğu, tip tür oranı, cümle yapıları (basit, karmaşık, sıralı), eylemsi sayısı ve eylemsi yoğunluğu açısından analiz edilmiştir. Anlatı örneğinden elde edilen değerler ile eleştirel düşünme sorularına verilen cevaplardan elde edilen değerlerde ortalama sözce uzunluğu, tip tür oranı, cümle yapıları (basit, karmaşık, sıralı), eylemsi kullanımları, eylemsi yoğunluğu karşılaştırılmıştır.Fables are a literary genre that deals with behaviors and thoughts that society either embraces or opposes. Syntax, which is the structural basis of language, is defined as arranging words into sentences for the speaker to express thoughts and feelings clearly and definitively. Critical thinking, on the other hand, encompasses certain mental processes such as identifying problems, distinguishing and controlling changes in problem situations. An increase in cognitive load in the content of speech leads to an increase in syntactic complexity. Various studies have found that the narration of fables and critical thinking questions related to fables reveal syntactic complexity in language. Although there are studies on the level of syntactic complexity in responses to critical thinking questions through fables in childhood and adolescent periods, there is insufficient data available for young adults. In this study, critical thinking and syntactic complexity in narrative examples obtained through fables were examined in healthy individuals aged 20-30 without a diagnosis of primary neurological/psychiatric illness. The data obtained from the study are planned to be used for the development of assessment tools and the establishment of a normative database for evaluating language and critical thinking skills of individuals with acquired brain injury aged 20-30 in clinical settings.Participants between the ages of 20-30 were first administered the Addenbrook Cognitive Assessment Battery, and 33 individuals who scored above 89 points were included in the study. Participants were asked to narrate a fable after reading it and were then asked questions related to the fable. Transcriptions of the narrative of the fable and the responses to critical thinking questions were converted into text. Transcriptions were analyzed in terms of average word length, type-token ratio, sentence structures (simple, complex, sequential), number of verbs, and verb density. Values obtained from the narrative example were compared with those obtained from the responses to critical thinking questions
Interpolation for neural-network operators activated with a generalized logistic-type function
Get PDFThis paper defines a family of neural-network interpolation operators. The first derivative of generalized logistic-type functions is considered as a density function. Using the first-order uniform approximation theorem for continuous functions defined on the finite intervals, the interpolation properties of these operators are presented. A Kantorovich-type variant of the operators Fna,epsilon\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document} is also introduced. The approximation of Kantorovich-type operators in LP\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}\end{document} spaces with 1 {a,\varepsilon} \end{document} and the Kantorovich variant of the operator Fna,epsilon\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}F_{n}{a,\varepsilon} $\end{document}, the approximation of various function examples is studied
Newly Identified Preventable Risk Factors for Neonatal Clavicle Fractures
Get PDFObjective: Despite its excellent prognosis, neonatal clavicular fracture often leads to complaints regarding the proficiency of the delivery process and increased obstetrician frustration. It is considered an unavoidable complication of birth because most risk factors are uncontrollable. This retrospective study aimed to determine the obstetric and neonatal characteristics associated with neonatal clavicular fracture at our institution. Methods: The data that obtained from the medical records of newborns delivered by spontaneous vaginal delivery and clinically diagnosed with clavicular fracture along with an x-ray confirmation were retrospectively evaluated. For each infant with a clavicular fracture, a healthy infant delivered by the same obstetrical team was enrolled as the control. Fetal, maternal, and delivery factors were evaluated in the fracture and control Results: Among the 106 newborn clavicle fracture cases, only 75 met the inclusion criteria and were enrolled in this study. Following the inclusion criteria, 75 healthy newborns were enrolled as controls. Birth weight and fetal distress were identified as fetal risk factors. Smoking during pregnancy, maternal hypothyroidism, and complications during pregnancy were maternal risk factors. Epidural anesthesia and instrumental Conclusion: Smoking during pregnancy, maternal hypothyroidism, and epidural anesthesia have not been identified as risk factors for neonatal clavicle fracture. The risk factors that are mostly mentioned are uncontrollable. However, smoking and epidural anesthesia are risk factors that can be prevented
Evaluating the Oncological and Functional Outcomes in 167 Patients Undergoing Laparoscopic Radical Prostatectomy: Could Laparoscopy Still be a Viable Option in Suitable Patients?
No full textAim: To evaluate the oncological and functional outcomes of 167 patients who underwent laparoscopic radical prostatectomy (LRP).
Materials and Methods: The retrospective study included 167 patients who were treated with LRP due to clinically localized prostate cancer between January 2007 and April 2012. Most of the patients were treated with the extraperitoneal approach. Preoperative evaluations included age, serum prostate-specific antigen (PSA) level, and biopsy Gleason score. Perioperative evaluations included duration of operative time and anastomosis time, blood loss (milliliter), and complications. Postoperative evaluations included length of hospital stay and catheterization time. Continence and erectile function were evaluated both pre- and postoperatively. The patients who used no pads or no more than one pad daily and the ones who had only a few urine leakages on effort or exertion were accepted as continent. Postoperative potency was defined as the ability to achieve sexual intercourse with or without the use of PDE-5 inhibitors.
Results: Mean age and mean operative time were 62.46.0 years and 220.5 +/- 45.6 minutes, respectively. Mean anastomosis time was 35.6 +/- 9.8 minutes. Mean serum PSA level and mean Gleason score were 17.5 +/- 9.97ng/mL and 6.16 +/- 0.42, respectively. Pelvic lymphadenectomy was performed in 94 patients and nerve-sparing procedures in 61 patients. The pathological analysis revealed positive surgical margin in 35 patients (20.9%). Bilateral and unilateral nerve-sparing LRP procedures were performed in 51 (30.5%) and 10 (6%) patients, respectively. At 12 months after surgery, 3 (1.8%) patients were using 2 or more pads per day, 19 (26.4%) patients were satisfied with erection, hardness, and duration of intercourse, and 9 (12.5%) patients had an erection with insufficient hardness and duration.
Conclusion: LRP is an acceptable method in localized prostate cancer due to its perioperative and early postoperative results
An Analysis of the Novel "Tutunamayanlar" from the Perspective of Lacanian Psychoanalysis
No full textOguz Atay's novel Tutunamayanlar (The Disconnected) is a postmodern work with its multi-layered structure and narration. The main problem in the novel is narrated through the internal revolts, alienation, and 'inability to hold on' to the life of the subjects who cannot create themselves in society and cannot adapt to the social discourse and the teachings imposed by the community. The context of the establishment stages of the subject is formed within the culture and by the sum of cultural influences. Since the formation of the unconscious subject, which is the epistemological object of psychoanalysis, is also handled through language, it appears to be difficult to consider the existence of the subject independently of cultural discourse. It is observed that the novels written with the technique of consciousness are notably relevant texts for the analysis of the unconscious, and they offer highly explanatory themes in terms of understanding the essential elements that form the character patterns. O & gbreve;uz Atay's novel Tutunamayanlar is a good text for psychoanalytic analysis with its fictional characteristic, use of stream-of-consciousness technique, and play-within-play narration. In this study, the character patterns and experiences of the subjects who are alienated from themselves-due to the split brought about by resisting the transition to the symbolic order and the fragmentation caused by remaining under the yoke of the imaginary register-in the novel Tutunamayanlar were interpreted against the background of the basic concepts (i.e., desire, alienation, other, Other, symbolic, and imaginary, real) in Lacanian theory
Serebral palsili çocuklarda nöral mobilizasyon tekniklerinin üst ekstremite fonksiyonları üzerine etkisi = The effect of neural mobilization techniques on upper extremity functions in children with cp
No full textSP tanılı bireylerde geleneksel fizyoterapi üst ekstremite rehabilitasyonu ile üst ekstremiteye uygulanan nöral mobilizasyon tekniklerinin, üst ekstremite fonksiyonelliği üzerine etkilerini araştırmaktır. Çalışmamıza dahil edilen 26 katılımcı, kontrol grubu ve nöral mobilizasyon olarak 2 gruba randomize edildi. Gruplar haftada 2 kez toplam 10 seans (1 seans 45-60 dakika) tedaviye alındı. Çalışmamızda olguların spastisitesi ''Modifiye Ashworth Skalası (MAS)'',Fonksiyonel Yetenekler ise ''Pediatrik Fonksiyonel Bağımsızlık Ölçeği (WEE-FIM), ''El Becerileri Sınıflandırma Sistemi (MACS)'', El ile İlgili Yetenekleri Ölçme(ABILHAND-Kids)'', ''Kutu ve Blok Testi(KBT)'', ''Dokuz Delikli Peg Testi(DDPT)'' ile kaba ve ince kavramalar ve ''Reaction Speed (RS)'' ise reaksiyon hızını ölçmek için kullanıldı. Tedavi sonrasında kontrol grubunda anlamlı değişim elde edildi(p<0,05). Nöral mobilizasyon grubunda da tedavi sonrası WEE-FIM,KBT,DDPT ve RS değerlerinde anlamlı değişim elde edildi(p<0,05). Gruplar arası karşılaştırılmada ise WEE-FIM,ABILHAND-Kids, KBT, DDPT ve RS değerlerinde anlamlı fark elde edilmiştir. SP' li bireylere uygulanan geleneksel fizyoterapiye ek üst ekstremite nöral mobilizasyon tekniklerinin, geleneksel fizyoterapi programına eklenerek daha iyi gelişmeler gösterdiği görülmüştür. Ancak bu sonuçların gelecekte yapılacak çalışmalar ile doğrulanması gerekmektedir.The aim of our study is to investigate the effects of traditional physical therapy upper extremity rehabilitation and neural mobilization techniques applied to the upper extremity on upper extremity functionality in individuals diagnosed with CP. The 26 participants included in our study were randomized into 2 groups as control group and neural mobilization. Groups were taken into treatment for a total of 10 sessions twice a week (1 session 45-60 minutes). In our study, the spasticity of the cases was measured with the "Modified Ashworth Scale (MAS)", Functional Abilities with the "Pediatric Functional Independence Measure (Wee-FIM), "Manual Ability Classification System (MACS)", "Assessment of Upper Extremity Related Abilities (ABILHAND-Kids)", "Box and Block Test (BBT)", "Nine Hole Peg Test (NHPT)" for gross and fine grasps, and "ReactionSpeed (RS)" was used to measure reaction speed. After treatment, significant change was obtained in the control group (p<0.05). In the neural mobilization group, significant changes were also obtained in WEE-FIM, BBT, NHPT, and RS values after treatment (p<0.05). In the comparison between groups, significant differences were obtained in WEE-FIM, ABILHAND-Kids, BBT, NHPT, and RS values. It has been observed that neural mobilization techniques applied to the upper extremities of individuals with CP, in addition to traditional physical therapy, showed beter improvements when added to thetraditional physical therapy program. However, these results needto be confirmed by future studies
Inhaled Aviptadil is a new hope for recovery of lung damage due to COVID-19
No full textMeeting Abstract
Conference Meeting: European-Respiratory-Society Congress (ERS
Yetişkinlerde beslenme durumu ve ağız, diş sağlığı ilişkisi / Relationship between nutritional status and oral, dental health in adults
No full textTezin amacı yetişkinlerde beslenme durumu ile ağız ve diş sağlığı arasındaki ilişkiyi saptamaktır. Çürük oluşumu, diş eti hastalıkları, diş erozyonu ve diğer ağız ve diş sağlığı hastalıkları ve beslenme arasındaki ilişkiyi göstermektir. Çalışmaya İstanbulda özel bir diş kliniğine gelen 102 kadın, 38 erkek olmak üzere 18-64 yaş arası yaş ortalaması 38,94 yıl olan 140 katılımcı yüz yüze anket yöntemi ile katılmıştır. Katılımcıların cinsiyet, yaş, su tüketimi, öğün sayısı, çiğneme süresi ve eğitim durumu ile genel bilgilerine ve boy, ağırlık, bel çevresi, bel/boy oranı, yağ oranı, kas oranı ve beden kütle indeksi (BKİ) ile antropometrik bilgilerine ulaşıldı. Yeme Tutum Testi-26 (YTT-26) ve Ağız Sağlığı Etki Ölçeği (OHIP-14) çalışmaya dahil edildi. 24 saatlik besin tüketim kaydı ile günlük makro ve mikro besin öğeleri hesaplandı. Bu araştırma kapsamında kadınların ortalama bel/boy oranı 0.49 ve BKİ değeri 24.77 kg/m2 normal değerleri gösterirken erkeklerin ortalama bel/boy oranı 0.53 ve BKİ değeri 27.95 riskli ve hafif şişman değerleri içindedir. OHIP-14 ve YTT-26 toplam puanı kadın katılımcılarda erkek katılımcılardan daha yüksek bulunmuş ve tüm katılımcılarda eğitim düzeyi arttıkça OHIP-14 puanlarının azaldığı, YTT-26 yeme kısıtlayıcı faktörünün arttığı sonucuna varılmıştır. Referans değerleri ile besin alımları karşılaştırıldığında katılımcılar yüksek protein, düşük E vitamini değerlerine sahip olduğu görülmüştür. Tüm katılımcılarda kalsiyum, B12, çinko, magnezyum eksikliği artan OHIP-14 skorları ile ilişkiliyken, erkeklerde C vitamini alımının yüksek OHIP-14 skorları ile ilişkili olduğu görülmüştür. YTT-26 yeme kısıtlayıcı faktörün artması ile OHIP-14 skorlarının artması yeme tutumu ile ağız diş sağlığı arasındaki ilişkiyi göstermektedir. Bu tez çalışmasında yeme tutumu ve besin öğeleri eksikliği veya yüksekliği ile ağız ve diş sağlığı ilişkisinin önemi vurgulanmış ve diyetisyen diş hekimi iş birliği ile klinik çalışmaların daha etkili olabileceği sonucuna varılmıştır.The aim of the thesis is to determine the relationship between dietary status and oral and dental health in adults. To show the relationship between caries formation, gingival diseases, tooth erosion and other oral and dental health diseases and nutrition. A total of 140 participants, 102 females and 38 males, aged 18-64 years with an average age of 38.94 years, who came to a private dental clinic in Istanbul, participated in the study by face-to-face questionnaire method. Participants' general information including gender, age, water consumption, number of meals, chewing time and educational status and anthropometric information including height, weight, waist circumference, waistto-height ratio, fat ratio, muscle ratio and body mass index (BMI) were obtained. The Eating Attitude Test-26 (EAT-26) and Oral Health Impact Scale (OHIP-14) were included in the study. Daily macronutrient and micronutrient intakes were calculated with 24-hour food consumption records. Within the scope of this study, the mean waist-to-height ratio of women was 0.49 and BMI value was 24.77 kg/m2 , while the mean waist-to-height ratio of men was 0.53 and BMI value was 27.95 kg/m2 , which were within the values of risky and slightly obese. OHIP-14 and YTT-26 total score were found to be higher in female participants than male participants and it was concluded that OHIP-14 scores decreased and YTT26 eating restriction factor increased as the educational level increased in all participants. When the reference values and nutrient intakes were compared, it was observed that the participants had high protein and low vitamin E values. In all participants, calcium, B12, zinc, magnesium deficiency was associated with increased OHIP-14 scores, while vitamin C intake was associated with high OHIP-14 scores in men. The increase in OHIP-14 scores with the increase in the YTT-26 eating restrictive factor shows the relationship between eating behaviour and oral dental health. In this thesis study, the importance of the relationship between eating attitude, nutrient deficiency or high intake and oral and dental health was emphasised and it was concluded that clinical studies with the cooperation of dietician dentist may be more effective