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Effect of herbs with anti-inflammatory activity on mastalgia and engorgement: a systematic review and meta-analysis
Get PDFIntroduction: Administration of nonsteroidal anti-inflammatory drugs (NSAID) has shown promising results in improving mastalgia and congestion, although it was associated with side effects. This study was conducted with the aim of investigating the effect of medicinal herbs with potential anti-inflammatory activity on periodic mastalgia. Methods: The search strategy was systematic screening of English electronic databases, including PubMed, Scopus, ISI Web of Science, Cochrane Library with no time restriction from inception to March 1, 2023. Jadad scale was used to assess the quality of included articles. Results: The findings of this analysis show that plant extracts with antioxidant potential can significantly reduce the severity of mastalgia compared to the control group SMD: 0.75 (-0.89 to-0.61; p=0.01: CI 95%)-also the heterogeneity index value is (I-2=0%; P = 0.5). Evening primrose oil and Vitagnus can significantly reduce the severity of mastalgia in comparison with control. Conclusion: Considering the importance of women's health, which plays an effective role in family functioning, and the fact that mastalgia can disrupt their activities, and on the other hand, medicinal plants with potential anti-inflammatory activity can have beneficial effects on the improvement of mastalgia. This method can be used as a useful method in improving periodic mastalgia
Sağlık Bilimleri Fakültesi öğrencilerinin akdeniz diyetine uyumu, uyku kalitesi ve açlık kan şekerlerinin değerlendirilmesi / Evaluation of mediterranean diet compliance, sleep quality and fasting blood sugar of Faculty of Health Sciences students
No full textBu araştırmanın amacı üniversite öğrencilerinin Akdeniz diyetine uyumu, uyku kalitesi ve açlık kan şekeri (AKŞ) arasındaki potansiyel ilişkileri ve seçilen demografik özelliklere göre bu değişkenler arasındaki olası farklılıkları belirlemektir. 01.11.2023- 31.05.2024 tarihleri arasında İstanbul Atlas Üniversitesi Sağlık Bilimleri Fakültesi öğrencileri ile yüz yüz anket yöntemi ile yapılan bu çalışmaya 162'si kadın, 136'sı erkek toplamda 298 kişi katılmıştır. Katılımcılar, gönüllü beyanlarına dayalı olarak ilgili anketleri tamamlamışlardır. Anketlerde katılımcıların sosyodemografik özellikleri, Akdeniz Diyeti uyumları, uyku kaliteleri, açlık kan şekerleri ve besin tüketim alışkanlıkları ölçülmüştür. Araştırmaya katılan üniversite öğrencilerinin yaş ortalamasının 23.05±3.66 yıldır. Beden Kütle İndeksi (BKİ) ortalamaları 24.67±6.35 kg/m2' dir. Boy ve kilo ortalamaları 171.27±12.07 cm ve 72.95±22.04 kg'dır. Katılımcıların Pittsburg Uyku Kalite İndeksi(PUKİ) puanları incelendiğinde grubun toplam puan ortalaması 7.32'dir. Bu kapsamda, üniversite öğrencilerinin uyku kalitelerinin kötü olduğu belirlenmiştir. Merkezi Dağıtım Sistemi puanları incelendiğinde grubun toplam puan ortalaması 3.94'tür. Bu kapsamda, üniversite öğrencilerinin Akdeniz diyetine uyumlarının orta kalitede olduğu gözlemlenmiştir. Açlık Kan Şekerleri Ölçüm Formu değerleri incelendiğinde AKŞ değeri normal aralıklarda (70-100 mg/dl) olan öğrencilerin, AKŞ değeri hipoglisemi (50-70 mg/dl) ve bozulmuş glikoz toleransı (100-125 mg/dl) olan öğrencilere göre Akdeniz diyeti uyum değerlerinin daha yüksek çıktığı ancak PUKİ değerlerini etkilemediği saptanmıştır. Sonuç olarak bu çalışmada üniversite öğrencilerinde Akdeniz diyetine uyum, uyku kalitesi ve AKŞ arasında potansiyel bir ilişki bulunabileceği gösterilmiştir.The aim of these programs is to determine the potential relationships between sleep, sleep quality, and fasting blood sugar (FBG) of the Mediterranean diet in university programs and the possible differences between these variables according to selected demographics. A total of 298 people, 162 women and 136 men, participated in this study, which was carried out with a face-to-face survey method with the certificate of Istanbul Atlas University Faculty of Health Sciences between 01.11.2023 and 31.05.2024. Participants completed relevant surveys based on volunteers' statements. Sociodemographic characteristics, Mediterranean Diet compliance, sleep quality, fasting blood sugar and food consumption production were measured in the surveys. The average age of university students participating in the research is 23.05±3.66 years. The average Body Mass Index (BMI) is 24.67±6.35 kg/m2. The average height and weight are 171.27±12.07 cm and 72.95±22.04 kg. When the Pittsburg Sleep Quality Index (PSQI) scores of the participants are examined, the total score average of the group is 7.32. In this context, it has been determined that university students' sleep quality is poor. When the Central Distribution System scores are examined, the total score average of the group is 3.94. In this context, it has been observed that university students' compliance with the Mediterranean diet is of moderate quality. When the Fasting Blood Sugar Measurement Form values are examined, students with FBG values within normal ranges (70-100 mg/dl) are more likely to follow the Mediterranean diet than students with hypoglycemia (50-70 mg/dl) and impaired glucose tolerance (100-125 mg/dl). It was found that compliance values were higher but did not affect PSQI values. In conclusion, this study showed that there may be a potential relationship between compliance with the Mediterranean diet, sleep quality and FBG in university students
Evaluation of the Effect of Early-Onset Steroid Treatment in the COVID-19-Positive Pregnant Women on Pregnancy Outcomes
Get PDFObjective: Coronavirus disease 2019 (COVID-19) is the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Acute respiratory distress and preterm delivery are the two major complications induced by SARS-CoV-2 infection during pregnancy. In the presence of dyspnea, the use of systemic corticosteroids was recommended in pregnant and non-pregnant groups. Our primary aim was to investigate the effect of early-onset steroid treatment on mortality and adverse effects in pregnant women with COVID-19. Our secondary aim was to investigate the effect of steroid treatment on the length of hospital stay and intensive care unit (ICU) stay, and duration of treatment. The study also investigated infection, preterm birth, and ideal body weight (lbw) in newborns.
Methods: In this retrospective study, 253 patients were divided into three groups according to steroid administration. In Group 1 patients (n:112), treatment was started at the time of hospitalization. In Group 2 patients (n:90), treatment was started at least 24 h after hospitalization. Group 3 consisted of patients (n:51) who did not receive steroid treatment. Methylprednisolone (32 mg/day) was given to pregnant patients with a gestational age below 24 weeks or above 34 weeks, and dexametazone (6 mg/day) was given in four doses followed by 32 mg/day methylprednisolone for the others (whose baby was at a gestational age of 24 weeks and above but less than 34 weeks).
Result: The hospital stay, ICU stay, and steroid administration time were significantly lower in the Group 1 when compared to the others (p < 0.05). The steroid treatment requirement was 4.4 days in Group 1 and 5.7 days in Group 2 (p < 0.05). While no death was observed in Group 1, one patient died in Group 2 and three patients died in Group 3. There was no difference between the groups in terms of complications, including preterm labor.
Conclusions: No death was also observed with early-onset treatment. Early-onset treatment may be beneficial for fewer hospitalizations, fewer ICU stays, and less mechanical ventilation requirement in pregnant women with COVID-19. In addition, with early treatment, the total number of steroid administration days was reduced, which is important in terms of reducing the risk of side effects
Youtube Ortamındaki Otizm ile İlgili Videoların Dil ve Konuşma Terapisti Bakış Açısıyla İncelenmesi
Get PDFOtizm spektrum bozukluğu (OSB), sosyal iletişim kurmada zorluk ve kısıtlı, tekrarlayan davranış veya ilgi alanlarıyla karakterize edilen nörogelişimsel bir bozukluktur. Bu bozukluk hakkında
bilgi almak isteyen bireyler, basılı veya çevrimiçi kaynaklardan yararlanabilmektedirler. Çevrimiçi platformlar, paylaşım yapan kişi ve paylaştığı içerik denetlenmeksizin, herkese açıktır. Bu
platformlardan biri de YouTube’dur. Ancak Youtube ortamında OSB ile ilgili videolarda içeriğin bilimselliği, doğruluğu ve yararı için bazı sorunlar göze çarpmaktadır. Bu çalışmanın amacı,
OSB ile ilgili Türkçe videoların bilgi kalitesinin, doğruluğunun ve izleyiciler açısından yarar düzeyinin dil ve konuşma terapisti bakış açısıyla incelenmesidir. Çalışmada, 28 Kasım 2021 tarihinde yeni oluşturulan bir YouTube hesabında arama çubuğuna “otizm” yazılarak bulunan Türkçe içerikli ilk 60 video incelenmiştir. Bu videolardan 33’ü çalışma kriterlerini (örn., süre, yeterli
beğeni sayısı) karşılamadığından dolayı, 27’si çalışmaya dahil edilmiştir. Videolar araştırmacılar tarafından Likert tipi bir formda belirlenen içerik değerlendirme kriterleri (örn., bilgi türü,
kalite, doğruluk) bakımından incelenmiştir. Değerlendirici I ve Değerlendirici II’nin tüm puanlamaları arasında anlamlı, pozitif yönlü, yüksek düzeyde bir uyum bulunmaktadır (r= -,83; p<
,01). Videoların dahil olduğu bilgi türü ve değerlendiricilerin puanları arasında anlamlı ve orta düzeyde bir uyum bulunmaktadır (x = ,592; p< ,01). Değerlendiricilerin puanlamaları ile beğeni
sayısı arasında anlamlı ve negatif yönlü bir ilişki bulunmuştur (r’ler ≥ -,443; p< ,05). Bu doğrultuda izlenme sayısı arttıkça Değerlendirici II’nin verdiği puanlar azaldığı görülmüştür (r= -,406;
p< ,05). Değerlendiricilerin puanları azaldıkça, videonun popülaritesini belirleyen bileşenlerin (beğeni sayısı ve izlenme sayısı) arttığı görülmüştür. Bu durumla ilişkili olarak, değerlendiriciler
videoların içeriklerinin sadece %33,3’üne (n=9) “yüksek düzeyde yararlı” olarak puan vermiştir. YouTube ortamında otizm ile ilgili sunulan içerik, genel olarak ele alındığında, mevcut bilgilerin yeterli olmadığı, içeriğin kalitesi-doğruluğu azaldıkça izlenme sayısı arttığı ve toplum yararı için bu bilgilerin doğruluğunun kontrolü ve niteliğinin geliştirilmesine yönelik düzenlemelere
ihtiyaç olduğu görülmüştür.Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by difficulty in social communication and restricted, repetitive patterns of behavior or
interests. Individuals who want to get information about this disorder can benefit from printed or online resources. Online platforms are open to everyone without controlling
the person sharing and the content they share. One of these platforms is Youtube. However, there are some problems regarding the scientificity, accuracy and usefulness of
the content in videos about ASD on YouTube. This study aims to examine the information quality, accuracy and usefulness of Turkish videos about ASD from the perspective of
a speech and language therapist. In the study, the first 60 videos with Turkish content found by typing “autism” in the search bar on a newly created YouTube account on 28
November 2021 were examined. Since 33 of these videos did not meet the study criteria (e.g., duration, sufficient number of likes), 27 of them were included in the study. The
researchers analyzed the videos using content evaluation criteria (e.g., type of information, quality, accuracy) determined in a Likert-type form and high inter-rater agreement
was found (r = -.83; p < .01). Considering the findings of the research, there was a significant and moderate agreement between the type of information included in the videos
and the evaluators’ ratings (x =,592; p<,01). A significant and negative relationship was found between the evaluators’ ratings and the number of likes (r ≥ -,443; p <,05). In this
direction, as the number of views increased, the scores given by Evaluator II decreased (r=-,406; p<,05). As the scores of the evaluators decreased, it was observed that the
components that determine the popularity of the video (number of likes and number of views) increased. In relation to this situation, the evaluators rated only 33.3% (n=9) of
the content of the videos as “highly useful”. When the content about autism in YouTube environment is considered in general, it is seen that the available information is not
sufficient, the number of views increases as the quality-accuracy of the content decreases, and there is a need for regulations to control the accuracy and improve the quality
of this information for the benefit of society
Evaluation of Glucose 6-Phosphate Dehydrogenase, Pyruvate Kinase, and New Generation Inflammation Biomarkers in Prolonged Neonatal Jaundice
Get PDFBackground and Objectives: To evaluate the clinical findings of glucose 6-phosphate dehydrogenase (G6PD) and pyruvate kinase (PK) deficiency in prolonged jaundice and to determine whether the systemic immune inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) can be used in the diagnosis of neonatal prolonged jaundice. Materials and Methods: Among full-term neonates with hyperbilirubinemia who were admitted to Medicine Hospital between January 2019 and January 2024 with the complaint of jaundice, 167 infants with a serum bilirubin level above 10 mg/dL, whose jaundice persisted after the 10th day, were included in this study. Results: G6PD activity was negatively correlated with NLR, SII, age, and hematocrit (Hct). There was a weak negative correlation between G6PD and NLR and a moderate negative correlation between G6PD activity and SII when adjusted for age and Hct. PK activity showed no significant correlation with G6PD, NLR, PLR, SII, age, and Hct. A linear relationship was observed between G6PD activity and SII and NLR. Conclusions: NLR and SII can be easily calculated in the evaluation of prolonged jaundice in G6PD deficiency has a considerable advantage. NLR and SII levels may contribute by preventing further tests for prolonged jaundice and regulating its treatment. It may be useful to form an opinion in emergencies and in early diagnostic period
Erişkin astımlı bireylerde obezitenin solunum fonksiyonları, akciğer difüzyon kapasitesi, fonksiyonel kapasite ve astım kontrolü üzerine etkisi = The effect of on respiratory functions, lung diffusion capacity, functional capacity and asthma control in adult asthmatic i̇ndividuals
No full textAstım, geçmeyen öksürük, hırıltılı solunum, nefes darlığı veya egzersiz esnasında artan nefes darlığı gibi şikayetlerle seyredilmekte olup hava yollarının kronik inflamatuar bir hastalığıdır. Obezite, vücuda besinler ile alınan besin öğelerinin oluşturduğu gücün harcanan güçten fazla olmasından kaynaklanan ve beden de oluşan yağ kütlesinin artması ile karakterize olan bir kronik hastalıktır. Beden kilo artışı ile oluşan yağ dokusunun toraks ve abdominal sistemde mekanik bir bası oluşturması sonucunda solunum hareketinin kısıtlandığı ileri sürülmektedir. Kısıtlanma ile azalan hava yolu solunum hacmini ve akciğer kapasitesini azaltmaktadır. Ayrıca; obezite ve astım arasındaki ilişki tam olarak açıklanmasa da obezitenin akciğerler üzerindeki inflamatuar etkisi ve mekanik etkisi olası etkiler olarak düşünülmektedir. Literatürde; astım hastalarında obezite grupları ile yapılan çalışmalarda fazla kilonun nefes almada zorluk yaşadıkları ve astım ataklarının arttığı belirtilmiştir. Bu nedenle; çalışmamızda erişkin astımlı bireylerde obezitenin solunum fonksiyonları, akciğer difüzyon kapasitesi, fonksiyonel kapasite ve astım kontrolü üzerine etkisini saptamayı amaçladık. Çalışmamıza, Şişli Kolan International Hospital, Göğüs Hastalıkları Bölümü'nde astım tanısı ile takip edilen, dahil edilme kriterlerine uyan ve gönüllülük esası ile çalışmaya katılmayı kabul eden 50 hasta dahil edildi. Hastalar obez olan ve olmayan astım hastaları olarak iki gruba ayrıldı. Tüm hastaların Beden Kütle İndeksi (BKİ), Astım Kontrol Testi (AKT), Solunum Fonksiyon Testi (SFT), Akciğer Difüzyon Kapasitesi (DLCO) ve Altı Dakika Yürüme Testi (6DYT) ölçümleri yapıldı. Veri analizi için SPSS v.26 programı kullanıldı. Shapiro-Wilk testi verilerin normal dağılım gösterip göstermediğini analiz etmek için kullanıldı. X2- testi ile niteliksel değişkenlerin analizi yorumlandı. Normal dağılım gösteren sayısal verilerde gruplar arası karşılaştırmada Indepedent Sample T-testi kullanıldı. Normal dağılım göstermeyen gruplar arası karşılaştırmalarda Mann Whitney U testi kullanıldı. Sağlıklı popülasyon verileri ile karşılaştırmak için One Sample T testi kullanıldı. Veriler arasındaki ilişki değerlendirmesi, Pearson veya Spearman korelasyon testi ile değerlendirildi. Tüm analizler için istatistiksel olarak anlamlılık düzeyi p0.05). Çalışmadaki grupların 6DYT testi değerlerini karşılaştırılmasında obez ve obez olmayan astım hastalarının gruplar arasında SpO2 bitiş değerlerinde (p=0.045), SKB başlangıç (p =0.017) ve bitiş (p= 0.002) değerlerinde, solunum frekansı bitiş değerlerinde (P=0.002), dispne ve yorgunluk algısını başlangıç (p=0.004, p= 0.0.18) ve bitiş (p =0.010, p=0.026) değerlerinde, bacak ağrısının bitiş değerlerinde (p= 0.045) ve yürüme mesafesinde (p=0.038) istatistiksel anlamda bir fark bulundu. BKİ'nin SFT, DLCO ve fonksiyonel kapasite arasındaki ilişkiyi incelediğimizde ise BKİ ve 6DYT mesafesi arasında orta düzeyde anlamlı korelasyon saptandı (r=-0.592, p= 0.028). Sonuç olarak; astım hastalarında hastalık şiddeti hafif düzeyde olsa bile fonksiyonel kapasitenin sağlıklı popülasyon verileri ile kıyaslandığında etkilendiği çalışmamızda gösterilmiştir. Obezitesi olan ve olmayan astımlı hastalarda solunum fonksiyonel kapasite parametrelerinde ve astım kontrolü arasında fark olmamasına rağmen fonksiyonel kapasite gibi yaşam belirleyicilerinden biri olan parametrede anlamlı farklar tespit edilmiştir. Bu da astım hastalarda obezitenin yaşam beklentisi açısından önemini göstermektedir. Anahtar Kelimeler: Astım, Akciğer Difüzyon Kapasitesi, Solunum Fonksiyonu, Obezite, Fonksiyonel KapasiteAsthma is a chronic inflammatory disease of the airways characterized by persistent cough, wheezing, shortness of breath or shortness of breath that increases during exercise. Obesity is a chronic disease characterized by an increase in body fat mass caused by the excess of the power generated by the nutrients taken into the body with food over the power expended. It is claimed that respiratory movement is restricted as a result of mechanical compression of the thorax and abdominal system by the adipose tissue formed by weight gain in the body. The reduced airway with restriction reduces respiratory volume and lung capacity. In addition, although the relationship between obesity and asthma has not been fully explained, the inflammatory and mechanical effects of obesity on the lungs are considered as possible effects. In the literature; in studies conducted with obesity groups in asthma patients, it has been reported that overweight patients have difficulty in breathing and asthma attacks increase. Therefore, we aimed to determine the effect of obesity on pulmonary function, lung diffusion capacity, functional capacity and asthma control in adult asthmatic subjects. In our study, 50 patients who were followed up in the Department of Chest Diseases, Sisli Kolan International Hospital, with a diagnosis of asthma, met the inclusion criteria and voluntarily agreed to participate in the study were included. Patients were divided into two groups as obese and non-obese asthma patients. Body Mass Index (BMI), Asthma Control Test (ACT), Pulmonary Function Test, Lung Diffusion Capacity (DLcO) and Six Minute Walking Test (6MWTM) were measured in all patients. SPSS v.26 program was used for data analysis. Shapiro-Wilk test was used to analyze whether the data were normally distributed. The analysis of qualitative variables was interpreted with X2-test. Indepedent Sample T-test was used for comparison between groups in numerical data showing normal distribution. Mann Whitney U test was used for comparisons between groups that did not show normal distribution. One Sample T test was used to compare with healthy population data. The relationship between the data was evaluated by Pearson or Spearman correlation test. Statistical significance level was accepted as p0.05). When the 6DYT test values of the groups in the study were compared, no significant difference was found between obese and non-obese asthma patients in SpO2 end values (p=0.045), SDB initial (p=0.017) and end (p=0.002) values, respiratory frequency end values (P=0. 002), dyspnea and fatigue perception at baseline (p=0.004, p= 0.0.18) and end (p=0.010, p=0.026), leg pain at end (p= 0.045) and walking distance (p=0.038). When we examined the relationship between BMI and SFT, DLCO and functional capacity, a moderate significant correlation was found between BMI and 6DYT distance (r=-0.592, p=0.028). In conclusion, our study showed that functional capacity is affected in asthma patients even if the severity of the disease is mild when compared with healthy population data. Although there was no difference in respiratory functional capacity parameters and asthma control in asthmatic patients with and without obesity, significant differences were found in one of the life determinants such as functional capacity. This shows the importance of obesity in terms of life expectancy in asthma patients. Keywords: Asthma, Lung Diffusion Capacity, Pulmonary Function, Obesity, Functional Capacit
The epigenetic changes are affected by sex and valproic acid treatment in a rat model of post-traumatic stress disorder
No full textPost-traumatic stress disorder (PTSD) presents distinct sex-specific differences in both symptom expression and treatment outcomes, with the underlying biological mechanisms still remain unclear. Epigenetic modifications, particularly histone acetylation, have been increasingly recognized as critical factors in the pathophysiology of PTSD. Valproic acid (VPA), a potent histone deacetylase (HDAC) inhibitor, has shown promise in modulating epigenetic responses and improving therapeutic outcomes is PTSD, though its effect may differ between sexes. This study aimed to explore the sex-specific epigenetic changes in response to trauma and the impact of VPA treatment in a rat model of PTSD induced by predator scent stress. Sprague-Dawley rats of both sexes were randomly assigned to stressed and non-stressed groups and treated with either VPA (100 mg/kg) or vehicle. Anxiety levels were assessed using the elevated plus maze, followed by analysis of histone H3 and H4 acetylation, HDAC activity, and c-fos expression in the hippocampus. Our findings revealed that traumatic stress led to increased freezing time and anxiety levels, with more pronounced effects observed in females. Additionally, we have identified sex-specific differences in hippocampal epigenetic modifications; stressed females exhibited higher H3 acetylation, and VPA-treated stressed males showed increased H4 acetylation. These results highlight the importance of considering sex differences in the epigenetic mechanism underlying PTSD and suggest that personalized therapeutic approaches may be necessary to address these complexities
Investigating Body Image and Self-Esteem in Kidney Transplant Patients: A Qualitative Study
No full textBackground:Kidney transplantation is one of the life-saving therapies for patients with end-stage renal disease, which affects a person's psychological, social, and physical well-being. How transplanted patients perceive their illness and their body can affect their physical and psychological recovery.Aim:This qualitative study was designed to evaluate self-esteem and body image in kidney transplant patients.Methods:The study involved 16 female renal transplanted patients. Data were collected using a two-part interview form developed by the investigators in accordance with the literature. We used Lundman's method to transcribe the interviews and coded the data from the interviews. The results of the study were discussed using the themes. The first three interviews were entered into MAXQDA, and then, additional interviews were analyzed.Results:Six main themes and 15 subthemes were generated based on the thematic analysis of the interviews with participants about body image and self-esteem. Themes included body acceptance, changes in body image, deterioration of social relationships, changes in self-esteem, spousal concerns, and organ perceptions. This study collected detailed data on body image, self-esteem, social relationships, and spouse/partner relationships after kidney transplantation.Conclusion:The change in participants' body image and self-esteem after kidney transplantation caused having negative feelings regarding sexual life, relationships, and social life and feeling unfamiliar with the transplanted organ
Turkish validity and reliability of the Haptotherapeutic Well-Being Scale
Get PDFObjectives Haptotherapy fosters a sense of unity between the body, mind, and emotions. In addition, it contributes to expanding the woman's perception of her pregnancy and developing a more positive attitude towards pregnancy and childbirth. The study aims to examine the Turkish validity and reliability of the Haptotherapeutic Well-Being Scale, which will be used to evaluate the well-being levels of haptonomy and haptotherapy practices in women. Design The study was methodological type. Methods The study conducted between October 20 and December 20, 2023, with 242 women who volunteered to participate by sharing forum pages on social media (Facebook, Instagram) via the web. Data were collected using a personal information form, including sociodemographic and obstetric characteristics and the Haptotherapeutic Well-Being Scale. Results The Haptotherapeutic Well-Being Scale consists of 14 items and five sub-dimensions. In confirmatory factor analysis, all path coefficients were statistically significant (p < 0.001). The overall Cronbach's Alpha and sub-dimension values of the scale are above 0.90. There is a positive and very strong correlation between all sub-dimensions of the scale (p < 0.001). Conclusion The Haptotherapeutic Well-Being Scale was found to be valid and reliable for the Turkish sample. Trials registrationhttps://clinicaltrials.gov identifier NCT06467188; registered June 14, 2024
AC-2306327-0000001 Association Between History of Polymerase Chain Reaction-verified COVID-19 Infection and Outcomes of Subsequent ST-Elevation Myocardial Infarction
No full textWhile the acute phase of coronavirus disease 2019 (COVID-19) is associated with worsening cardiac outcomes, it is unclear whether it affects the outcome of patients with ST-segment elevation myocardial infarction (STEMI) after the acute phase. In addition, while many studies compared the course of STEMI during the COVID-19 pandemic with the years before the outbreak, we evaluated the course of STEMI during the pandemic according to whether or not patients had history of COVID-19. Patients diagnosed with STEMI during the ongoing COVID-19 pandemic were included in the study. The Ministry of Health database was analyzed retrospectively, and patients with (n = 191) and without (n = 127) a history of polymerase chain reaction (PCR) confirmed COVID-19 infection were divided into groups. Clinical and angiographic characteristics were assessed. The rates of in-hospital major adverse cardiac events (MACE) were higher in those who had a history of PCR-verified COVID-19 infection. Angiographic and procedural findings indicating successful reperfusion were better in patients without a history of COVID-19. A history of COVID-19 infection (odds ratio 1.40, 95% confidence interval 1.25-1.60, P < .01) independently predicted MACE. A history of COVID-19 infection is a predictor of worse outcomes following coronary intervention and in-hospital MACE among patients with STEMI