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    Assessment of Inventory Management Performance of Anticancer Medicines and Associated Challenges in Selected Cancer Treatment Centers in Ethiopia: A Multicenter Cross-Sectional Study

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    Background: Cancer is a concern worldwide and next to cardiovascular diseases, is the second largest cause of death worldwide. A cancer drug is a pivotal part of cancer treatment and influences the survival rate of cancer patients worldwide. Appropriate management of anticancer medicines at different stages of supply chain is important. Inventory management is a core part of supply chain management that helps to maintain a steady supply of patients. Objective: This study aimed to assess the inventory management performance of anticancer medicines and associated challenges in cancer treatment centers in Ethiopia, 2025. Method: A mixed method study was conducted from March 1- 30, 2025. The quantitative data were collected using self-administered questionnaires and observational checklists. The qualitative data were gathered through in-depth interviews with key informants. For data entry Epi-data version 4.5 used whereas SPSS version 26 for analysis. The fisher‟s exact test was used to identify predictors of the dependent variable. Statistical significance was determined at p < 0.05. Qualitative data were analyzed manually using the thematic content analysis technique. Result: The average availability of anticancer medicines was 46.9%. The mean duration of day‟s sock out was 82 days. Of the assessed total bin cards 110 (84.6%) were updated. Whereas, 122 (93.8%) of bin cards were accurately filled. Over the past year, 20.6% (3,574,505.97 ETB) (27,208.7912 US $) of anticancer medicines were wasted due to damage and expiration. The cancer treatment centers met 77.9 % of criteria for good storage practice. Inventory management performance had statistically significant association with the factors such as IPLS training, supportive supervision, and the facility stock tacking practices at p < 0.05 shown by fisher‟s exact test. Stock out of anticancer medicines, budget constraints, lack of capacity building training, lack of standard separate storage area for anticancer medicines were the major challenges identified. Conclusion: The inventory management performance of anticancer medicines was poor, resulting in stock out with long duration, high wastage rate, and poor storage condition. Problems related to availability of products, capacity building training, and storage conditions were identified. Therefore, Ministry of Health, assessed health facilities, and Ethiopian pharmaceuticals Supply Services should take measures to improve them

    Determinants Of Anemia Among Pregnant Women Attending Antenatal Care At Public Health Facilities In Gambella Town, Gambella, Southwest Ethiopia, 2025.

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    Background: Anemia during pregnancy is a major public health problem with serious consequences for both mothers and their newborns. Despite the availability of antenatal care (ANC) services in Ethiopia, the burden of anemia remains high, and its determinants vary across settings. However, evidence on factors contributing to anemia among pregnant women in Gambella town is limited. Objective: To identify the determinants of anemia among pregnant women attending antenatal care at public health facilities in Gambella Town, 2025. Methods: An institution-based unmatched case–control study was conducted from May to July 2025 among 250 pregnant women (125 cases and 125 controls) attending ANC at public health facilities of Gambella Town. The cases were pregnant women with hemoglobin concentration <11 g/dl, and controls were those with hemoglobin ≥11 g/dl. Data were collected using interviewer-administered questionnaires and laboratory measurements. Data were entered into Epi Info 7.2.2.6 and analyzed using SPSS version 27. Bivariate and multivariable logistic regression analyses were performed, and Adjusted Odds Ratios (AOR) with 95% Confidence Intervals (CI) were used to identify determinants of anemia. Statistical significance was declared at p < 0.05. Results: A total of 250 pregnant women participated with a 100% response rate. Key factors associated with anemia among pregnant women included rural residence (AOR = 3.65, 3.65, 95% CI: 1.03–12.9), no formal education (AOR = AOR = 3.78 95% CI: (1.72,8.33), history of blood loss during pregnancy (AOR =4.6 95% CI: 1.16,18.04), history of malaria (AOR = 4.0495% CI: 1.66–9.87), chronic disease (AOR = 5.82 95% CI: 1.81,18.74), and low (AOR = 7.10, 95% CI: 1.31–38.6) or medium (AOR = 2.52,95% CI: 1.17–5.41) dietary diversity. Conclusion and recommendation: Anemia among pregnant women in Gambella town was significantly associated with rural residence, illiteracy, history of blood loss, malaria infection, chronic diseases, and poor dietary diversity. Strengthening health education, improving dietary practices, preventing and treating malaria and chronic illnesses, and promoting maternal education should be prioritized to reduce the burden of anemia in this population

    Under nutrition and Associated Factors among Adolescent Pregnant Women in Gomma District, Jimma Zone, Southwestern Ethiopia

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    Background; Addressing undernutrition in adolescent pregnant women can help break the intergenerational cycle of malnutrition where malnourished mothers give birth to malnourished children, perpetuating a cycle of poor health outcomes. In Ethiopia; adolescent pregnancy is common in rural areas of the country due to mainly cultural practices of early marriage and other socio-economic related factor. However, there is a limited research in the study setting concerning the level of undernutrition and associated factors among adolescent pregnant women. Objective; This study aims to assess the prevalence of undernutrition and associated factors among pregnant adolescent women in Gomma district, Jimma Zone, Southwest Ethiopia, 2024 Methods; a community based cross sectional study was conducted on 600 adolescent pregnant women from ten randomly selected rural and two urban kebeles of Gomma district from September to October -1/2024. Data were entered into Epi-Data version 3.1 and exported to SPSS version 26 for further analysis. Binary logistic regression analysis method was used to show an association between dependent variable and predictor variables. Multivariable binary logistic regression was done to identify factors independently associated with undernutrition among adolescent pregnant women in Gomma district, Jimma Zone. The level of statistical significance will be declared at P < 0.05 with 95%CI and AOR. Results; A total of 588 pregnant adolescent were included in this study with the response rate of 98.0%. This study revealed that the mean and standard deviation age of the study participants were 17.76±1.23 with minimum and maximum age of 15 and 19 respectively. This study revealed that the prevalence of under nutrition among adolescent pregnant women was 206 35.0% (95% CI 31.5-39.3%). In multivariate logistic regression model, intention of pregnancy (AOR=2.03, 95 % CI; 1.31-3.14, p=0.002, frequency of eating meal per-day (AOR=4.59, 95% CI 1.26-16.68, P=0.020), experienced eating problem because of pregnancy (AOR=, 95% CI 1.07-2.51, P=0.005), gestational age, wealth status (AOR=2.90 (1.47-5.73, p=0.002) and dietary diversity score (AOR=2.80, 95% CI; 1.66-4.73, p<0.001) were found to have significant association variables with the occurrence of undernutrition among adolescent pregnant women in Gomma District, Jimma Zone, Oromia, Ethiopia. Conclusion and recommendations; This study revealed that every one out of three adolescent pregnant women was having undernutrition in the study setting. Factors affecting the occurrence of undernutrition were intention of pregnancy, frequency of eating meal per-day, experienced eating problem because of pregnancy, wealth status, gestational age and dietary diversity score. Programs should focus on improving dietary diversity, meal frequency, and early antenatal care while addressing unintended pregnancies, eating problems, and poverty to reduce undernutrition among adolescent pregnant women

    Supply Chain Agility and Associated Factors among Pharmaceutical Suppliers in Sidama Regional State, Ethiopia

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    Background: Supply Chain Agility allows pharmaceutical suppliers to operate effectively in a fast-changing environment by enabling quick and flexible responses. This study aims to assess the supply chain agility practices, identify factors influencing agility, and explore challenges in implementing these practices in both the public and private sectors of pharmaceutical suppliers in the Sidama region of Ethiopia. Methods: From June 2024 to July 2024, a mixed method study design was concurrently implemented among pharmaceutical suppliers in the Sidama region, Ethiopia. Quantitative data were collected through questionnaires using a five-point Likert scale. A stratified random sampling method was used to include a total of 327 participants, consisting of 126 from customers of the Ethiopian Pharmaceutical Supply Service (EPSS) and 201 from customers of private suppliers. The quantitative data were entered in Epidata V 4.6, and analyzed using SPSS version 25.0, where both descriptive and multiple linear regression analyses were conducted. For the qualitative component, a purposive sampling technique was employed to conduct interviews with 12 key informants. The resulting data were then analyzed using thematic analysis. Results: A total of 313 completed responses were obtained, resulting in a response rate of 95.7%. 141 (45%) expressed disagreement with the variety of products offered by suppliers. The majority, 173 (55.3%), reported experiencing delays in receiving their products. 92 (29.4%) agreed that suppliers frequently experience stock outs. The adjusted R-squared value of 0.339 indicates that 33.9% of the variance in supply chain agility is explained by the independent variables in the model. The study found that ICT (β=0.434, p<0.001), collaboration (β=0.101, p=0.044), innovations, budget, and data quality significantly affect supply chain agility. A one-unit increase in ICT adoption is associated with a 0.434-unit increase in supply chain agility. The p-values (<0.001) indicate a statistically significant association between ICT and supply chain agility. Major challenges identified in supply chain agility implementation included supply shortages, inadequate technologies, poor data quality, foreign currency fluctuations, import restrictions, and high tariffs on imported products. iii Conclusion: Supply chain agility is poorly practiced regarding order fill rate, flexibility, product variety, and lead time, though pharmaceutical suppliers demonstrate strong practice regarding competency. Major challenges to implementing supply chain agility include supply shortages, technological limitations, inadequate human resources, poor data quality, financial constraints, and reliance on foreign companies due to low local production rates. The study identified statistically significant associations between ICT, collaboration, innovation, budget, and data quality. Recommendation: The researcher recommends that pharmaceutical suppliers to enhance their use of information communication technology (ICT). It is also recommends that pharmaceutical suppliers to collaborate with customers to share knowledge and best practices, as well as work with other partners in the supply chain. Further recommends the Regional Health Bureau, Zonal Health Office, Woreda Health Office, and health facilities to work on providing adequate training and ongoing supervision to address and improve challenges related to supply chain agility

    Investigating Gender difference in Reading Habit and Reading Strategy Use: The case of Grade 11 Students at Adu sigmo Higher Secondary School.

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    The main purpose of the study was to assess gender difference in reading habit and reading strategy use: the case of grade eleven students at Adu Sigmo Higher Secondary School. To conduct the study, descriptive design with a mixed research method was used. Questionnaire and interview for both male and female students were the instruments used to collect data for the study. The sample of the study consisted of two classrooms, which contains102 students among these sixty two male and forty female students were selected randomly for the study using simple random sampling technique. Data were analyzed using both quantitative and qualitative methods of data analysis. The closed-ended data were analyzed by frequency counting and percentage quantitatively, whereas, qualitative data analysis was used to analyze structured interview in words. At the end, both data forms were organized and presented thematically.The findings of the study revealed that there was no adequate practice of reading habit and reading strategy use especially female students in EFL classes to develop their reading habit in Adu Sigmo Higher Secondary School. The finding of the study suggested that male students practiced reading habit in integrating reading strategy use in Adu Sigmo Higher secondary School. The findings of the study also showed that female students did not have good reading habit and different strategies use to improve their reading problems in relation to participating reading task as the content of the reading activities are assimilated in the reading text to develop their reading habit in EFL classes. Therefore, it was recommended that both male and female students should have good reading habit in integrating reading strategy use in all aspect

    Time to Recovery and Its Predictors among Under-Five Children with Severe Pneumonia at Jimma Town Public Hospitals: A Retrospective Follow-Up Study

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    Background: Severe pneumonia is a leading cause of morbidity and mortality in under-five children, accounting for 14% of global under-five deaths in 2019. In Ethiopia, it is a priority disease under routine surveillance. While recovery times have been studied in various regions, most studies were limited to specific settings. Evidence on recovery patterns and predictors in Jimma, where severe pneumonia remains highly prevalent, is scarce. Objective: To assess the time to recovery from severe pneumonia and its predictors among under-five children admitted to Jimma University Medical Center and Shenen Gibe General Hospital. Methods: A facility-based retrospective follow-up study was conducted among 272 under five children admitted with severe pneumonia between July 1, 2021, and July 30, 2024 at public hospitals in Jimma town. A simple random sampling technique was used to select eligible medical records. A structured tool was used to extract data from medical records. Data were double-entered in EpiData 3.1 and exported to Stata 15 for analysis. The Kaplan Meier was used to estimate the survival function, and group differences were assessed using the log-rank test. Variables with P < 0.25 in the bivariate analysis were entered into the multivariable Cox proportional hazards regression to identify independent predictors of recovery time, with significance set at p < 0.05. Results: A total of 272 medical records reviewed and were retained for analysis. The median age was 10 months and 152 (55.9%) resided in rural areas. Of the total, 219 (80.5%) achieved clinical recovery and the total accumulated person-days at risk was 1,913 days. The overall median recovery time from severe pneumonia was 5 days (IQR: 3–9). Children who were malnourished (AHR = 0.57, 95% CI: 0.39–0.84), not exclusively breastfed (AHR = 0.49, 95% CI: 0.31–0.80), or not fully vaccinated (AHR = 0.72, 95% CI: 0.53–0.98) had a lower hazard of recovery compared to children with no malnutrition, exclusively breastfed and fully vaccinated respectively. Conclusion: The overall median recovery time was 5 days. Recovery from severe pneumonia was delayed among under-five children who were malnourished, not exclusively breastfed or not fully vaccinated at admission. Strengthening child nutrition, promoting exclusive breastfeeding, and ensuring full vaccination coverage are essential to improve recovery time in under-five children with severe pneumonia

    Echocardiography and Electrocardiographic Findings among Hypertensive Patients at the Follow-Up Clinic of Jimma Medical Center: A Cross-Sectional Study

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    Hypertension is one of the most common cardiovascular diseases worldwide and a major contributor to structural and functional heart abnormalities. Early detection of cardiac involvement in hypertensive patients is crucial to prevent complications. Echocardiography and Electrocardiography are valuable tools for evaluating cardiac changes associated with hypertension. Objective: This study aimed to assess Echocardiography and Electrocardiographic findings among hypertensive patients visiting chronic follow up at Jimma Medical Center, Jimma, Ethiopia Methodology: A hospital-based cross-sectional study was conducted at Jimma Medical Center from February10-March 20, 2025. The study was focused on hypertensive patients undergoing chronic follow-up during the specified period. The inclusion of participants was determined through a systematic random sampling technique. Data Collection and Analysis: Data collected by kobo toolbox was exported to excel and then, to IBM SPSS version 26 software package for analysis. Both bivariate and multivariable logistic regression models was employed. In the bivariate analysis, variables with a P-value less than 0.25 were considered candidates for inclusion in the multivariable analysis. In the multivariable logistic regression model, variables with a P-value less than 0.05 were taken as statistically significant. Results: All the 268 study participants had Electrocardiography (ECG) and Transthoracic echocardiography. ECG evaluation showed high rates of Left Ventricular Hypertrophy, 35.4% by Sokolow-Lyon criteria and 28.4% by Cornell voltage criteria. Left anterior fascicular block was found in 23.5% of participants, and QTc is prolonged in 7.1% of hypertensive individuals. TTE evaluation showed high rates of concentric LVH 39.2% and left ventricular internal v diastolic diameter(LVIDd) is enlarged in 11.2% participants. In multivariable logistic regression, Age ≥50Yr ( AOR, 4 [95% CI, 1.76-9.05], P=0.001), DBP≥90mmHg( AOR, 4.3[95% CI, 2.0 9.1], P<0.001), duration of hypertension≥10yrs( AOR, 2.42 [95% CI, 1.17-5.02], P=0.017), total cholesterol≥240mg/dl( AOR, 7.2[95% CI, 1.5-36], P=0.01), and BMI 25-29Kg/m2( AOR, 4 [95% CI, 1.7-8.7], P=0.001), were significantly associated with LVH on ECG and on TTE LVH has significant association with Age ≥50yrs( AOR, 3.6[95% CI, 1.8-7.2], P<0.001), DBP≥90mmHg( AOR, 2.02 [95% CI, 1.1-3.97], P=0.023), and BMI 25-29 Kg/m2( AOR, 3.43 [95% CI, 1.6-7.2], P=0.001), and obesity( AOR, 9.4 [95% CI, 1.9-46.8], P=0.006)

    Impact of land use land cover change onwoody species Diversity in gechi district of buno bedele zone, Southwest ethiopia

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    Globally, the alarming rate of deforestation and land use land cover changes are among the most significant drivers of environmental degradation and biodiversity loss. The study area has been influenced by rapid population growth, agricultural land expansion, deforestation, and poor management practices. This research aimed to assess the impact of land use and land cover changes on woody species diversity within the area. The study utilizing the cross-sectional research design. The study corporate both primary and secondary data including satellite imagery from 1983,1993,2003,2013 and 2023 sourced from USGS.A multi stage random sampling techniques was employed. The accuracy of LULC maps demonstrated a categorization accuracy between 85% and 93% with kappa coefficient exceeding 0.8, indicating strong agreement with the ground truth data

    የማንበብ ብሌሃትን በግሌጽ ማስተማር አንብቦ የመረዲት ችልታንና የማንበብ ተነሳሽነትን ሇማጎሌበት ያሇው ሚና (በኢታንግ 2ኛ ዯረጃ ትምህርት ቤት በ10ኛ ክፌሌ የአማርኛ ቋንቋ ኢ-አፇፇት ተማሪዎች ተተኳሪነት)

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    የዙህ ጥናት ዋና ዓሊማ የማንበብ ብሌሀቶችን በግሌጽ ማስተማር የተማሪዎችን አንብቦ የመረዲት ችልታና የማንበብ ተነሳሽነት ሇማሳዯግ ያሇውን አስተዋጽዖ መመርመር ነው፡፡ ይህንን ዓሊማ ሇማሳካት ሁሇት የ10ኛ ክፌሌ ምዴቦች ተመርጠው ከፉሌ ሙከራዊ ጥናት ተከናውኗሌ፡፡ ሇጥናቱ የተመረጡት የሁሇቱ ምዴብ ተማሪዎች ቅዴመ ትምህርት ፇተና እንዱፇተኑና የጽሐፌ መጠይቅ እንዱሞለ ከተዯረጉ በኋሊ የተገኙት መረጃዎች በገሊጭ ስታቲስቲክስና በባዕዴ የናሙናዎች ቲ-ቴስት ተተንትነዋሌ፡፡ የትንተናው ውጤት እንዲመሇከተው በሁሇቱ ቡዴን ተማሪዎች መካከሌ ጉሌህ የአንብቦ መረዲት ችልታና የማንበብ ተነሳሽነት ሌዩነት የሇም (P>0.05)፡፡ በመቀጠሌም የሙከራ ቡዴን ተማሪዎችን የማንበብ ብሌሀቶችን በግሌጽ በማስተማር፣ የቁጥጥር ቡዴን ተማሪዎችን ዯግሞ በሌማዲዊው የትምህርት አቀራረብ ሇ5 ሳምንታት (ሇ10 ክፌሇ ጊዛዎች) ተምረዋሌ፡፡ ትምህርቱ ሲጠናቀቅም ዴህረ ትምህርት ፇተናንና የጽሐፌ መጠይቅን በመጠቀም መረጃዎች ተሰብስበው በገሊጭ ስታቲስቲክስና በባዕዴ የናሙናዎች ቲ-ቴስት ተተንትነዋሌ፡፡ የትንተናው ውጤት እንዲመሇከተው የሙከራ ቡዴን ተማሪዎች ከቁጥጥር ቡዴን ተማሪዎች በጉሌህ የሚበሌጥ አንብቦ የመረዲት ችልታና የማንበብ ተነሳሽነት አሊቸው (P<0.05)፡፡ ይህም የሚያመሇክተው የሙከራ ቡዴን ተማሪዎች አንብቦ የመረዲት ችልታና የማንበብ ተነሳሽነት ከትምህርቱ በፉት ከነበረው በጉሌህ መሻሻለን ነው፡፡ ከዙህም በመነሳት የማንበብ ብሌሀቶችን በግሌጽ ማስተማር የተማሪዎችን አንብቦ የመረዲት ችልታና የማንበብ ተነሳሽነት ሇማሳዯግ ጉሌህ አስተዋጽዖ አሇው የሚሌ መዯምዯሚያ ሊይ ተዯርሷሌ፡፡ በዙህም መሰረት የአማርኛ ቋንቋ መምህራን የማንበብ ክሑሌን ሲያስተምሩ የማንበብ ብሌሀቶችን በግሌጽ እንዱያስተምሩ፤ የመጻሕፌት አ዗ጋጆች የተሇያዩ የማንበብ ብሌሀቶችንና አተገባበራቸውን የተመሇከቱ ማብራሪያዎች በመጻሕፌቱ ውስጥ እንዱያካትቱ፣ እንዱሁም ላልች አጥኚዎች ተዯጋጋሚ ጥናቶችን እንዱያዯርጉ አስተያየት ተሰጥቷሌ፡

    The impact of enset production on smallholder farmer’s Income on masha district, sheka zone, south west ethiopia

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    Agriculture is a crucial driver of long-term growth and economic development, significantly contributing to GDP globally and in Africa, particularly in Ethiopia. Root and tuber crops, such as enset, sweet potato, potato, cassava, and yams, play a key role in ensuring food security and income. However, enset farming faces challenges including inefficient traditional methods, insufficient extension activities, market imperfections, and limited research, which hinder its full potential. This study examines the impact of enset (Ensete ventricosum) production on smallholder farmers' income in the Masha district, Sheka Zone. Utilizing a mixed-methods approach, data was collected from 270 households, supplemented by key informant interviews and focus group discussions, to provide comprehensive insights into enset production's efficiency and benefits. The study utilized descriptive statistics, binary logistic regression, and propensity score matching models to assess enset crop production determinants and its impact on smallholder farmers' income. Significant associations were found between enset farming participation and demographic, socioeconomic, and institutional variables

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