UAX Archive (Univ. Alfonso X el Sabi)
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Essential Tremor and Mortality in Older Adults: The Role of Word Recall, a Measure of Episodic Memory, in a 23-Year Follow-Up Study
Get PDFBackground: The association between essential tremor (ET) and mortality risk remains uncertain. This study investigated the impact of episodic memory performance, measured through a word recall task, on mortality risk in ET within the Neurological Disorders in Central Spain (NEDICES) cohort, a population-based study of older adults. Methods: Participants were followed until death or 31 December 2017, and divided into four groups based on ET status and memory performance (errors in the 37-Minimental Examination¿s three-word recall task). Cox proportional hazards models estimated mortality hazard ratios (HRs), and the Relative Excess Risk due to Interaction (RERI) assessed additive interactions. Results: Among 3998 participants, 3432 (85.8%) died over a median follow-up of 11.2 years. ET patients with episodic memory impairments had a higher mortality risk (HR = 1.25, 95% CI: 1.06¿1.46) compared with controls with similar deficits (HR = 1.19, 95% CI: 1.09¿1.28), whereas no significant increase was observed for ET patients without memory impairments (HR = 0.95, 95% CI: 0.74¿1.21). RERI analysis revealed no significant additive interaction between ET and memory impairment (fully adjusted RERI: 0.11 [95% CI: ¿0.19¿0.41]). Episodic memory impairments, regardless of ET status, were strongly associated with Alzheimer¿s disease as a primary cause of death. Conclusions: These findings highlight the independent contribution of episodic memory impairment to increased mortality risk, with ET modestly amplifying this effect without significant interaction. Further research is needed to explore shared pathophysiological mechanisms between ET and neurodegenerative conditions.
Keywords: essential tremor; older adults; episodic memory; NEDICES cohort; mortality risk: cognitive impairment; population-based surve
La metaloproteinasa 9 (MMP-9) en pacientes con aniridia congénita
No full textBermejo Fernández, Lucía; director de proyecto: López García, José Santiago2024-2025Grado en MedicinaFacultad de Medicin
Más de allá de la diabetes: Inhibidores del cotransportador sodio-glucosa tipo 2 en Enfermedad Renal Crónica e Insuficiencia Cardíaca
No full textGallego Chicano, Alba; director de proyecto: Guerrero Monjo, Sandra2024-2025Grado en FarmaciaFacultad de Ciencias de la Salu
Mejora del aprendizaje a través de cambios en los hábitos de salud de los estudiantes
No full textRico Gil, Isabel; director de proyecto: San Juan Fernández, Mónica2024-2025Máster Universitario en Profesorado de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanza de IdiomasFacultad de Ciencias de la Educació
Consecuencias de la adicción al scroll en menores
No full textPérez Ranea, Luis; director de proyecto: Merino del Amo, Nuria2024-2025Máster Universitario en Profesorado de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanza de IdiomasFacultad de Ciencias de la Educació
Restauraciones cerámicas mínimamente invasivas en el sector anterior
No full textAmstutz , Margot Jacqueline Monique; director de proyecto: Pérez Hernández, Ricardo2024-2025Grado en OdontologíaFacultad de Odontologí
Circuitos de fluidos, suspensión y dirección: la suspensión
No full textMarquez Campos, Adrián; director de proyecto: Camús Rosillo, Carmen2024-2025Curso de Formación Pedagógica y Didáctica para Profesorado de Formación Profesional y DeportivaFacultad de Ciencias de la Educació
Propuesta de un curso e-learning y de un juego de mesa educativo para la enseñanza de las categorías gramaticales a estudiantes con TDAH
No full textPolanco Mota, Shariely Deyanira; director de proyecto: Llamas Salguero, Fátima2024-2025Máster Universitario en Tecnología Educativa y Competencias Digitales DocentesFacultad de Ciencias de la Educació
Doxorubicin - Cyclophosphamide Protocol in Dogs with Splenic Haemangiosarcoma and Haemoabdomen: A Retrospective Case Series
Get PDFThis retrospective case series describes 21 dogs with stage II splenic haemangiosar coma (HSA) and spontaneous haemoabdomen treated with splenectomy followed by
a doxorubicin¿cyclophosphamide protocol. Median overall survival was 92 days, with
longer survival observed in dogs completing three or more chemotherapy cycles. The
regimen was well tolerated, with low haematological and gastrointestinal toxicity. Mainte nance metronomic chemotherapy was administered in a small subset, and it was associated
with prolonged survival. While the sample size is modest, the homogeneous and clinically
specific cohort provides hypothesis-generating observations on feasibility, tolerability, and
time-aware associations that warrant cautious interpretation and prospective confirmation.
No clinical or laboratory variable at diagnosis was independently associated with outcome.
While limited by retrospective design and small sample size, this study provides focused data on a specific clinical presentation and supports the feasibility of structured adjuvant
treatment in dogs with splenic HSA and haemoabdomen.202
Diagnóstico de lesiones orales potencialmente malignas mediante aplicaciones de inteligencia artificial
No full textBenzeghiba, Amel; director de proyecto: Migueláñez Medrán, Blanca2024-2025Grado en OdontologíaFacultad de Odontologí