JOURNAL OF HEALTHCARE AND LIFE-SCIENCE RESEARCH
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INSULT KELIB CHIQISHIDA KORTIZOL, ADRENALIN VA NOADRENALINNING AHAMIYATI
Get PDFInsult (miyadagi qon tomirlarining buzilishi natijasida yuzaga keladigan serebrovaskulyar hodisa) paytida tananing gormonal, neyroendokrin javob tahlil qilinadi. dastlabki bosqichda adrenalin va noradrenalin tezkor faollik bilan chiqariladi, bu neyrovaskulyar reaktivlik va gemodinamikaning oshishiga olib keladi. Keyinchalik kortizol miqdori ortishi stress javobini tezlashtiradi. Adrenalin yurak urish tezligi, qon bosimi va qon oqimini kuchaytiradi, noradrenalin esa asab tizimining ogohlantiruv funksiyasini ta’minlaydi. Kortizol esa metabolik energiya resurslarini faollashtiradi, immunitetni bostiradi. Bu gormonlar insultning birlamchi reperfuziya bosqichida muvozanatni saqlashda muhim, ammo ortiqcha chiqarilishi miya shikastlanishini kuchaytirishi mumkin. Uzluksiz giperkortizolizm gipoksiya, neyroinflamatsiya va oksidlovchi stressni orttiradi. Bu jarayonlarda neyroprotektiv va neyrodegenerativ mexanizmlar o‘rtasidagi o‘zaro ta’sirlar aniqlanadi. Uzoq izlanishlar shuni ko‘rsatiki, bu gormonlarning insult rivojlanishida ahamiyati juda katta. Shu jumladan O‘zbekistonda ham bir qancha eksperimental va klinik tatqiqotlar olib borilmoqda
UNVEILING THE POTENTIAL OF RACHANA SHARIR: A RESEARCH IN AYURVEDA
Get PDFRachana Sharir, the branch of Ayurveda dealing with anatomical structures and their interrelationships, offers vast potential for research and development. In the contemporary era, the integration of Ayurvedic concepts with modern anatomical and physiological sciences has become crucial for validating traditional knowledge and exploring new frontiers in healthcare. This article delves into the scope of research in Rachana Sharir, exploring classical texts, contemporary methodologies, and future possibilities for evidence-based advancements. Rachana Sharir, a branch of Ayurveda dealing with human anatomy, provides a fundamental understanding of body structures and their interrelationships. Rooted in classical Ayurvedic texts such as the Sushruta Samhita, Charaka Samhita, and Ashtanga Hridaya, it describes the human body in terms of Sira (veins), Dhamani (arteries), Snayu (ligaments), Peshi (muscles), Asthi (bones), Sandhi (joints), and Marma (vital points). The ancient wisdom of Rachana Sharir, when integrated with modern anatomical and clinical knowledge, has immense potential for advancements in medical science
KORRUPSIYANING PAYDO BO‘LISHI, UNGA QARSHI KURASHDAGI YONDASHUVLAR
Get PDFKorrupsiya-bu jamiyatni turli yo‘llar bilan iskanjaga oladigan dahshatli illatdir. U demokratiya va huquq ustuvorligi asoslariga putur etkazadi, inson huquqlari buzilishiga olib keladi, bozorlar faoliyatiga to‘sqinlik qiladi, hayot sifatini yomonlashtiradi va odamlar xavfsizligiga tahdid soladigan uyushgan jinoyatchilik, terrorizm va boshqa hodisalar ildiz otib, gullashi uchun sharoit yaratib beradi. Inson manfaatlari huquqiy tajribamizda eng yuksak va eng ustun qadriyat bo‘lishini barchamizning ongimizga singdirish juda-juda og‘ir kechmoqda
STRUCTURAL AND FUNCTIONAL FEATURES OF THE LEFT VENTRICLE OF THE HEART AND THEIR RELATIONSHIP WITH ARTERIAL HYPERTENSION
Get PDFThe left ventricle (LV) is a critical cardiac chamber responsible for systemic circulation. Arterial hypertension significantly affects its structure and function, leading to pathological remodeling and cardiovascular complications. This article explores the relationship between the structural and functional characteristics of the LV and arterial hypertension. It highlights the mechanisms of adaptation, pathological changes, and clinical implications. Understanding these aspects is essential for improving diagnosis and management of hypertensive heart disease
THE THERAPEUTIC EFFICACY OF A PREPARATION DERIVED FROM THE KOVUL MEDICINAL PLANT IN THE TREATMENT OF ODONTOGENIC PURULENT INFLAMMATION WITHIN THE MAXILLOFACIAL REGION
Get PDFThe medicinal plant Kovul is found in the mountainous regions of Uzbekistan, particularly in areas such as the Tian Shan and Pamir-Alay mountain ranges. These mountain ranges are located in the eastern and southern parts of the country, where the rugged terrain and diverse climate foster rich biodiversity. The flora in these areas is adapted to the high altitudes and harsh conditions, contributing to the unique medicinal properties of plants like Kovul. The Tian Shan mountains, in particular, are known for their ecological richness and have long been a source of herbal remedies and traditional medicinal plants used by local communities.
The Department of Maxillofacial and Plastic Surgery at BRMCC treated 127 patients with odontogenic purulent inflammation, ranging in age from 28 to 43. 60 patients (30 males and 30 females) made up the control group, while 67 patients (30 males and 37 females) made up the experimental group. Each group included patients with different diagnoses: 35 patients had retromolar purulent periostitis in the right lower jaw, 40 patients had purulent periostitis of the upper jaw, 25 patients had purulent phlegmon of the left lower jaw, and 25 patients had purulent phlegmon of the upper jaw
POST-LIVER TRANSPLANTATION MEDICAL COMPLICATIONS
Get PDFLiver transplantation (LT) is widely accepted as an effective therapeutic modality for a variety of irreversible acute and chronic liver disease. The success of liver transplantation has increased steadily over the last two decades and several advances have been made since the first human liver transplant. This procedure has become routine with an excellent outcome in terms of both quality and length of survival
ЖАРРОХЛИК АМАЛИЁТИДА БИТИШМАЛИ КАСАЛЛИКНИНГ РИВОЖЛАНИШИДА ЙЎЛДОШ КАСАЛЛИКЛАРНИНГ ЎРНИ
Get PDFБитишмали касаллик (адҳезив касаллик) жарроҳлик амалиётида кенг тарқалган муаммолардан бири бўлиб, унинг ривожланиши турли омиллар, жумладан, йўлдош касалликлар билан боғлиқ. Ушбу мақолада битишмали касаллик патогенезида йўлдош касалликларнинг роли, уларнинг жарроҳлик аралашувдан кейинги асоратларни кучайтириш механизмлари ва олдини олиш стратегиялари таҳлил қилинади. Тадқиқот натижалари жарроҳлик амалиётида битишмали жараёнларнинг олдини олиш ва даволаш усулларини такомиллаштиришга қаратилган илмий асосларни тақдим этади
ANESTHESIA IN PATIENTS WITH THYROID PATHOLOGIES
Get PDFThe article presents the results of preoperative preparation, anesthesia and surgical treatment of patients operated on for non-toxic nodular goiter. A new approach to preoperative preparation for thyroid surgery is described. The effectiveness in the preoperative period of using the modified method of preoperative preparation using sibazon and droperidol and anesthesia with the use of ketamine and the advantages of this method compared with other methods of general anesthesia are shown
DIAGNOSIS OF COMMON EARLY COMPLICATIONS OF TYPE 2 DIABETES IN A MODERN INTERPRETATION
Get PDFStudy and analysis of the prevalence of complications in patients with type 2 diabetes based on city registry data for 2012-2015. Compared with the data. General Background: Type 2 diabetes mellitus (T2DM) is a significant global health concern, often leading to severe complications, including microvascular and macrovascular disorders. Specific Background: Early diagnosis and management of diabetic complications are crucial to reducing morbidity and mortality. However, understanding the epidemiological trends in the prevalence of these complications is essential for optimizing treatment strategies. Knowledge Gap: Although studies have assessed diabetes complications, limited research has focused on long-term prevalence trends based on registry data, particularly in specific geographic regions. Aims: This study analyzes the prevalence and trends of early complications in patients with T2DM based on registry data from 2012 to 2015, identifying key patterns in disease progression. Results: The findings indicate a decline in the prevalence of diabetic nephropathy (16.9% to 9.8%) and autonomic neuropathy (10% to 2%), alongside reductions in myocardial infarction (13% to 5.8%) and stroke (14% to 6.7%). Conversely, arterial hypertension remains the most prevalent complication (50.3%-73.9%). Novelty: This study provides a contemporary epidemiological assessment of diabetes complications, emphasizing the impact of systematic registry-based monitoring on improving patient outcomes. Implications: The results highlight the importance of targeted prevention and treatment programs, particularly for cardiovascular complications, to enhance the life expectancy and quality of life in diabetic patients
МЕТРОЛОГИЧЕСКИЕ ХАРАКТЕРИСТИКИ ПОЛУПРОВОДНИКОВОГО СЕНСОРА ОКСИДА УГЛЕРОДА
Get PDFThere are publications in the literature on the prevalence of tuberculosis and associated diseases, as well as surgical care for patients with tuberculosis with urological pathology. The clinic of tuberculosis and the effectiveness of its treatment, including pulmonary tuberculosis, is largely determined by the presence of intercurrent diseases that aggravate a specific process and complicate its treatment. The prevalence of attendant pathology in patients with pulmonary tuberculosis ranges from 80% to 100%