Central Asian Journal of Theoretical and Applied Science
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Faculty of Geography, Universitas Gadjah Mada, Indonesia
No full textВ статье рассматривается проблема психологического состояния курсантов-лётчиков авиационных училищ, их эмоционально-волевая устойчивость. Осуществляется поиск направлений учебно-воспитательного процесса, с целью формирования у курсантов личностных качеств, которые необходимы будущим офицерам-лётчикам
Oxidative Stress in Systemic Lupus Erythematosus Causes Inflammation and Cellular Damage
No full textSystemic lupus erythematosus (SLE) is a complex autoimmune disease affecting various organs, driven by a combination of genetic, environmental, and hormonal factors leading to immunological dysregulation. The disease is characterized by the production of autoantibodies, inflammation, and end-organ damage, with oxidative stress playing a significant role by inducing functional changes in DNA, lipids, and proteins. Current understanding of SLE pathophysiology highlights the importance of oxidative stress biomarkers in predicting disease progression and guiding treatment. Despite available treatments like corticosteroids and immunosuppressants, there remains a need for more effective therapies with fewer side effects. This research aims to investigate the relationship between oxidative stress and SLE progression, utilizing biomarkers to improve early diagnosis and treatment decisions. By analyzing oxidatively modified molecules in SLE patients, the study seeks to enhance our understanding of disease mechanisms and identify new therapeutic targets to reduce morbidity and mortality
The Effectiveness of the Cotton Cleaning System on Foreign Saw Gins
No full textIn order to study the effectiveness of the cotton ginning system of cotton gins in local cotton gins equipped with foreign technology, research work was carried out on the "Imperial" saw gin with 170 saws manufactured by the US company "Lyummus" in the cotton ginning enterprise "Karvon" of the Bukhara region. The research work was carried out in Bukhara-6 selection cotton with initial moisture content of 9.6% and 12.8%, dirtiness of 3.5% and 9.4%, grade I and III grade 2. As a result of the research, the contamination of cotton after the supplier-cleaner was equal to 1.0% and 1.4% on average according to the varieties. In this case, the cleaning efficiency of the supplier-cleaner was on average 24.2% and 27.5%, which showed that it was 5.8 (abs)% and 7.5 (abs)% less than the cleaning efficiency of the supplier-cleaner in the technical characteristics of gin. . During cleaning of high and low grade cotton, separation of cotton from the supplier-cleaner to waste occurred, and the amount of separated cotton was on average 18% and 25% in relation to the mass of waste. Gin productivity in ginning of ginned cotton was on average 1750 kg/h and 1210 kg/h, which showed average 24.5% and 26.8% less than gin passport productivity.
The mass fraction of defective fiber and impurities in the post-ginning fiber was 3.56% and 4.83% on average, and seed hairiness was 15.56% and 17.3% on average.In this case, the hairiness of the seed was higher by 5.1 (abs) % and 5.8 (abs) % compared to the industry standard, and it was observed that along with the denatured seed, the fiber suitable for weaving was transformed into fluff. As a result of the conducted research, despite the fact that the cleaning efficiency of the "Imperial" chainsaw gin supplier is higher than the cleaning efficiency of the local gin supplier-cleaner, on average, 18% and 25% of the cotton is separated into waste when cleaning cotton from large impurities, and additional equipment and electricity are used to clean the cotton separated into waste. was studied. In addition, it was found that the gin supplier-purifier has a complex construction, which causes difficulties in its use and consumes 9 kW more electricity than the local gin supplier-purifier. Due to the fact that the foreign gin supplier-cleaner has the above-mentioned shortcomings, it was studied that it is necessary to improve the cleaning efficiency and improve the quality of cotton by improving the local gin supplier-cleaner
Determine Phesochemical Properties of Some Bottled Drinking Water Brands
No full textThe current study was conducted in Al-Hilla city on 10 factories that produce bottled water. Physical and chemical tests were conducted on the studied samples. the PH values ranged between (7.2-8). The electrical conductivity was (99-153) μS/cm and the nitrate values were (0.1-0.9) ppm. The values of Total hardness ranged between (20-84) ppm, while the elements of potassium and sodium ranged between (0.2-2.9) ppm, (1.2-13) ppm, respectively. The turbidity values ranged between (0.52-1.5) NTU and The TDS values ranged between (75-102) ppm, All physical and chemical tests were within the parameters recommended by the World Health Organization (WQI) and the Iraqi Ministry of Healt
Determining the Levels of Few Inflammatory Cytokines in Lab Animals Exposed to Various Concentrations of Salmonella typhi Lipopolysaccharides
No full textThe current study aims to quantify the amounts of inflammatory cytokines exposed to different lipopolysaccharide concentrations isolated from Salmonella typhi. Using the chloroform-methanol procedure, LPS was isolated from S. typhi and then dried with a lyophilizer device. The purity of LPS was confirmed by gas chromatography-mass spectrometry (GC-MS). Doses of 0.625, 1.25, and 2.5 mg/100 g body weight (B.W) were used in this experiment. Four groups of white mice were injected with three doses of LPS, with each group receiving three replicates, aged (2–3) months injected intraperitoneally (IP) with three doses of LPS every 48 hours, and followed by a final booster dose one week later. Subsequently, blood samples were collected and serum levels of interleukin-1 (IL-1) and interleukin-7 (IL-7) were measured by enzyme-linked immunosorbent assay (ELISA) method. The results showed that IL-1 levels were (9.933 ± 0.513 , 9.033 ± 0.568 and 10.700 ± 0.101) pg/ml at the concentrations of 0.625, 1.25, 2.5) mg/100 g (b.w) respectively, compared to the control sample which was (5.933 ± 0.890). Furthermore, the levels of IL-7 were 304.000 ± 0.208, 301.866 ± 0.276 and 333.566 ± 0,164) pg/ml at 0.625, 1.25, and 2.5 mg/100 g (b.w) respectively, while the control sample was (290.700 ± 0.112) pg/ml. The gain of lipopolysaccharide from S. Typhi provoked the immune system inside the injected rats, leading to the secretion of cytokines like IL-1 and IL-7 in any respect tiers used in comparison to the manage. In addition, the lifestyles of IL-1 could limit the manufacturing of IL-7
Study of the Effect of Proteus Mirabilis Bactria on the Kidney Tissue of Laboratory Mice
No full textThis study aimed to investigate the effects of Proteus mirabilis on the kidney tissues of laboratory mice. A total of 30 urine samples were collected from female patients with urinary tract infections. The presence of Proteus mirabilis was confirmed through bacteriological tests. Mice were orally dosed with P. mirabilis over two weeks, and their kidneys were later examined for pathological changes. Histological analysis revealed various stages of degeneration, lymphocyte infiltration, and glomerular damage. The study concluded that P. mirabilis induces significant kidney tissue damage, including necrosis, hemorrhage, and congestion, particularly at higher bacterial concentrations
Assessment of Lead, Cadmium, Nickel, and Chromium Levels in the Blood of Street Beggars in Kirkuk Governorate, Iraq
No full textBeggars constantly expose themselves to environmental pollutants, which pose significant health risks. Among these pollutants, heavy elements are important pollutants that this marginalized community in Kirkuk Governorate, Iraq in particular, and in the world in general is exposed to. Lead Pb, cadmium Cd, chromium Cr, and nickel Ni levels were estimated in the blood of beggars in the streets of Kirkuk Governorate, Iraq, and the results obtained were compared with the results of the control group. The study included 75 beggars and 75 control groups, all of whom were males and of the same age groups. Flameless atomic absorption technology was used to estimate the levels of all elements. The results showed a significant increase in the levels of all heavy elements under study in the blood of beggars, as the lead level was 14.2 micrograms/liter in beggars compared to 2.5 micrograms/liter in the control group. Cadmium was 3.1 μg/L versus 0.92 μg/L, chromium was 2.3 μg/L in beggars versus 0.67 μg/L in the control group, while nickel was 3.9 μg/L versus 0.86 μg/L. In general, the concentrations of heavy metals in the blood of adults were higher than in teenages and young children
Synthesis, Diagnosis and Study of Molecular Docking for 4-(4-amino-5-mercapto-4H-1,2,4-triazol-3-yl) Phenol and Its Coordination with Some Metals
No full textTriazol is an important nitrogen heterocyclic compound, containing three nitrogen atoms and two carbon atoms. Where triazole and its complexes were prepared by Acid Hydrazide (A1) was synthesis from the condensation of ester with hydrazine hydrate using ethanol absolute as a solvent. The next step involved the reaction of hydrazide acid, carbon sulfide (CS2), and ethanol to produce oxadazole (A2). Then, haydrazine hydrate was mixed with the triazole (A3) oxadiazole derivative. The complexes A4–A7 were produced by the reaction of the ligand (A3) with binary metal salts of the transition elements Co (II), Ni (II), Cu (II), and Mn (II). The reaction ratio of every complex that was produced was 1:1. The Ligand is Metal. The ligand was described using FT-IR, 1H, 13C-NMR, and elemental analysis (C.H.N.S.M.). The generated compounds were diagnosed using infrared spectroscopy (FT-IR) techniques, magnetic sensitivity at ambient temperature, and other approaches. The results showed that the atoms of sulfur and nitrogen coordinate ligand bidentate. The form of the octahedral complex is as follow
The Impact of the Four-pillar Strategy on the Creative Thinking of Fine Arts Students
No full textThe research aimed to find out the impact of the strategy of the four pillars, in creative thinking, for students of fine arts, in addition to adjusting the creative thinking skills of fine arts students, according to the strategy of the four pillars, to achieve this, the researcher used the experimental method, with his experimental and control groups, and a test (before and after), for the two samples of the research, this was done by choosing the researcher his research community, in the intentional way, as it was students of fine arts, University of Babylon, for the academic year / 2023 2024 / morning study, the third stage of the Department of Art Education, and in the way The researcher chose his research sample, as it was (40) male and female students, (20) for experimental, and the same for the control, the researcher adopted the scale of creative thinking for Yusra Hassan 2004, after verifying its suitability for the sample studied, and then built (10) units for teaching graphics, according to the strategy of the four pillars. The researcher carried out a pre-test for the two samples of the research, then proceeded to apply the curriculum prepared by him to the experimental sample, without the control, which was taught in the curriculum prescribed for graphics, when the researcher finished implementing his educational program, he conducted a test for the two sample
Preparation and Characterization of Tetrazole Derivatives Derived from Schiff Bases and Evaluation of Biological Activity
No full textThis study included the preparation of heterogeneous pentagonal rings derived from tetrazole ring by reacting Schiff's radicals derived from 6-methyl-2-uracil and using them as nuclei in the preparation with sodium azide using tetrahydrofuran solvent. The compounds were confirmed using physical measurements such as color, melting point, and product percentage. Spectroscopic measurements, such as the infrared spectrum and nuclear magnetic resonance spectrum, were also used to determine the composition of the compound. The effectiveness of some of these compounds was also tested against two types of Gram-positive and Gram-negative bacteria using amoxicillin as an antibiotic