European Journal of Medical and Health Research
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BOTOX’s Mechanism, Diversity Considerations, and Therapeutic Potential in Cosmetic, Medical, and Dental Practice
Get PDFThis review provides a comprehensive overview of the societal pressures of maintaining a youthful appearance and the increasing popularity of BOTOX injections for aesthetic purposes. It discusses the motivation behind BOTOX use for personal psychological gains, partly driven by social media pressure and societal expectations. Ethical considerations and potential psychosocial consequences of cosmetic BOTOX are also addressed.The article delves into the explanation of what BOTOX is and how it works, emphasizing its use for cosmetic and medical purposes, such as treating spasmodic dysphonia and hyperhidrosis. When used appropriately, it highlights the rarity of complications and adverse effects associated with BOTOX. BOTOX’s historical use and development, from its initial medical applications to its widespread adoption in cosmetic procedures, are outlined. Further explored is the prevalence of BOTOX use among different socioeconomic classes, races/ethnicities, ages, and genders, highlighting disparities and emerging trends. It summarizes the effectiveness and safety of BOTOX injections for facial wrinkles and its non-cosmetic uses (e.g., treating migraines, hyperhidrosis, and pain management). The review describes BOTOX’s uses in dentistry, including its therapeutic benefits and safety considerations.It also discusses the possible therapeutic advantages of BOTOX injections in managing psychological conditions, including depression, anxiety, and body dysmorphic disorder (BDD). The diagnostic applications of BOTOX and its mechanism of action are briefly explained.The article concludes with a summary of BOTOX’s beneficial and adverse effects and the constraints on access to and use of BOTOX treatments. It acknowledges the limitations of BOTOX research and the need for further investigation to address these limitations.Abbreviations: BDD: Body Dysmorphic Disorder; FDA: U.S. Food and Drug Administration; QoL: Quality of Life; ROM: Range of Motion; SES: Socioeconomic Status; SNAP-25: Synaptosomal-Associated Protein 25; TMD: Temporomandibular Joint Disorde
Challenges for Conducting Research during Pandemics. A Narrative Review
Get PDFBackground: Research during pandemics presents unique challenges and opportunities that are crucial for advancing scientific knowledge and improving public health responses. This study's topic is significant due to the unprecedented disruptions caused by pandemics like COVID-19, which have impacted all stages of the research process. This study aims to identify and analyze research challenges during pandemics and propose strategies to overcome these obstacles.Methods: A narrative literature review was conducted, focusing on the challenges of conducting research during pandemics. A comprehensive search strategy was implemented, using databases such as PubMed, Google Scholar, and Web of Science, with keywords including "pandemic," "research challenges," "COVID-19 research," "SARS research," "clinical trials during pandemics," "best practices," and "research strategies." The review covered studies published from 2004 to 2023, including previous pandemics like SARS, H1N1, and COVID-19. Relevant articles were identified through database searches and manual reference list reviews.Discussion: The review revealed multidimensional challenges affecting various stages of the research process. Political, economic, administrative, regulatory, logistical, ethical, and social challenges were identified. Logistical difficulties were prevalent, such as limited access to laboratories and supply chain disruptions. Ethical challenges, including informed consent and data privacy, were magnified during health crises. The mental health impacts on researchers and participants were also significant, with increased anxiety and depression affecting engagement and well-being.Conclusion: The study concludes that while pandemics introduce considerable challenges for conducting research, there are also valuable lessons and best practices that can be applied in future crises. Effective strategies include investing in digital infrastructure, developing flexible ethical frameworks, implementing adaptive clinical trial designs, and supporting mental health for researchers and participants. By learning from the COVID-19 pandemic, the research community can better prepare for and navigate future pandemics, ensuring the continuity and effectiveness of scientific investigations
The role of Frequency Modulation in the Magic Light Anti-Cancer Therapy
Get PDFThe role of frequency modulation in the Magic Light anti-cancer therapy was investigated both in theory and in clinical trials. The existence of at least four different optimal modulation frequencies is required for cancer treatment. This was disclosed and is explained by the presence of at least of four different kinds of cancer cells within the same cancer, whereby each cancer cell type has its own speed of proliferation. The application of several different frequencies for cancer treatment in turn, during each treatment session, thus allows the Magic Light therapy to cure any type of cancer faster and completely
Evaluation of the Efficacy of Aqueous and Alcoholic Extract of Cinnamomum zeylanicum Against the Growth of Candida albicans Isolated from Different Clinical Samples
Get PDFThis experiment was carried out in the laboratory of the Husseini Teaching Hospital in Karbala for the year 2020-2021 with the aim of studying the effect of the active compounds in the aqueous and alcoholic extract of cinnamon in inhibiting the growth of Candida albicans yeast. By GC-MS technique and also a qualitative detection of some active compounds in cinnamon bark, the results showed that cinnamon contains glycosides, tannins, resins, saponins and phenols. The aqueous and alcoholic extract showed a difference in the diameters of inhibition, where the highest inhibiting diameter reached (50 mg/ml) 32 mm and the lowest inhibition diameter was 25 mm, while the concentration (25 mg/ml) reached the highest inhibition diameter of 30 mm and the lowest inhibition diameter of 22 mm and concentration (12.5 mg). /ml) the highest inhibition diameter reached 28 mm and the lowest inhibition diameter was 17 mm, while the concentration (6.25 mg/ml) reached the highest inhibition diameter 25 mm, and the minimum damping diameter is 12 mm
One Mobile Phone Model of Chinese Medical Qigong Therapies
Get PDFBackground: Qigong is one characteristic therapy of traditional Chinese medicine(TCM), and it has benefited more and more. However, to our best knowledge, the physical model of Qigong therapies remains unknown. Method: Based on the progress of modern science, one physical model of Qiong therapy-mobile phone model is presented. Discussions: The main points of the model are: one normal healthy person is just like one mobile phone which is communicating well in the net, the internal Qi of the person is just like the standing electromagnetic waves inside of the mobile phone, and the external Qi is just like the travelling electromagnetic waves outside of it; the best Qigong state of one healthy person is considered just like one continuing optimal mobile phone, with development one generation by one generation and with strong signal communicating well in net, not like one fixed to one generation. The reason of one person is sick is the electromagnetic waves inside of the person deviates from standing waves or the electromagnetic waves outside deviates from travelling waves. It is the first step to correct the deviation for one patient to cultivate Qigong and finally to get the optimal state of integrating the Three Adjustments into one. The rationality of the mobile phone model and the essence of Qi in the model are discussed
The Role of Memory in Psychotherapeutic Treatment
Get PDFMuch data is now available on the effectiveness of psychotherapies on the stability of the change achieved and on the therapeutic relationship, which, in its various conceptual declinations, constitutes the most incisive predictor of outcome. Moreover, the principle that psychotherapy is more effective when it is more specifically oriented towards the psychopathological factors underlying the symptoms is becoming increasingly clear. Many studies have confirmed that the most effective psychotherapists can create deep alliances with a diverse typology of patients, regardless of the relational skills and attachment patterns the patient possessed at the beginning of therapy. An aspect not always considered is ‘memory reconsolidation,’ which allows modifying or replacing dysfunctional emotional responses with more functional ones
Fangs of Snake (Sarpadangstra): A Literary Study
Get PDFSnakes are the most commonly experienced creature by the human society. There are many incidences of bite by the snakes resulting in a number of problems including death. Snakes bite usually due to (1) fear, (2) being injured, (3) for self protection and (4) to use the substance as food. In all circumstances the main weapon used by the snakes is the fangs (Dangstra). Though not in all situations, when snakes bite, poison is injected through the modified teeth (Fangs that can be closely co-related with Dangstra mentioned in the Ayurvedic classics). A study of the Ayurvedic classics to explore the concept on the fangs is considered by the author important and time tested
Probability Threshold Optimization for Classification of COVID-19 Patients with Higher Mortality Risk: A Case Study from the North-Eastern Region in North Macedonia
Get PDFResearch goal: The goal of this research is to identify, compare and demonstrate some available methodological approaches which are sufficient to draw the optimal probability threshold, particularly in the case of classification of infected patients with increased risk of dying from COVID-19. The presented methodologies generate identical results if the purpose of classification is to maximize the prognosis accuracy from the point of sensitivity. Sample: As part of the whole population, the sample counts 1013 patients from the north-eastern region of the Republic of North Macedonia. Methodology: The general methodological frame used to calculate and forecast the probabilities of death outcome from COVID-19 is the binary logistic regression. In extension, we applied the rules of maximum sum and maximum product as well as the so-called Youden Index for the purpose of optimization of the probability threshold. The principals of the ROC curve in addition with the Index of Union was also helpful for the same purpose. Prognosis accuracy was evaluated through the status of patient according to the rules of “golden standard” in which sensitivity, specificity and the general accuracy of prognosis play a crucial role. Results: Accordingly, the results from the research indicate that the optimal probability threshold or “cut-off” point that provides maximal accuracy, particularly from the perspective of sensitivity in the prognosis is 0,1. In that point, the coefficient of sensitivity (the percentage of true positively predicted death cases in respect to all death cases from the sample) is measured 85,71%. Conclusion: The applied methodological approaches offer scientifically sound foundations in the context of mortality risk evaluation and classification of COVID-19 patients. Then targeted patients will be subject of precaution with strict measures, protocols and more aggressive treatment in order to minimize the chances of death outcome
Use of Nursing Staff Competency Assessment for Quality Improvement in Urgent Care Clinic in PHC, Riyadh
Get PDFThe Primary Health Care (PHC) of Family & Community Medicine (FCM), Prince Sultan Military Medical City (PSMMC), manages a huge number of patients, both in urgent care clinics and in other PHC services. In March 2024, they implemented an initiative to improve the competence training and assessment for the nursing staff at urgent care clinics for FCM PHC. Improving nurse performance will support providing quality healthcare services. Local problem is the high load of patients attending the clinics with due requirements by physician order, such as medication, dressing, and ECG (electrocardiogram). The aim is to improve nursing staff performance in order to accommodate the increased demand for health care services. Centers of PHC of FCM are rendering their services during the weekdays from 07:00 until 16:00. The sample data came from the mega centers that are extending their services for more than 8 hours and/or lasting until 24 hours, including weekends. Centers like KAMAH and Wazarat are working for 24 hours and seven days a week, with six sessions with 12 nurses each day. While Salam, Oreija, and SRHC are rendering their services for three sessions with six nurses a day. Lastly, Yasmeen Center is rendering its services for four sessions with eight nurses per day. From the six centers, 308 sessions in a month with 196 nurses in total are providing quality health care service in urgent care clinics. In March 2024, they started the initiative of improving the competence of the nurses through monitoring, direct observation for nurse performance, auditing, counseling, and giving incentives. From March 2024 until July 2024, there is an upward trend of procedures completed by the nursing staff conducted in urgent care clinics in PHC. A total of 31,658 medication administration services were provided during the seven months of the quality improvement project; the majority were conducted in Wazarat –14,648 medication administration. With a total of 14,573 dressings and an ECG of 6,652. There is a noticeable upward improvement in urgent care clinic services provided by the nursing staff following the quality improvement project conducted in March 2024. It is recommended to generalize this quality improvement in nurse competence, training, and assessment will have a positive impact on quality health services provided in PHC
Improving Healthcare Services through Reducing Zero-Stock Reports in PHCs Riyadh, Saudi Arabia
Get PDFBackground: Quality improvement initiative to reduce zero stock items through improved demand supply chain system in primary healthcare centers.Aim: This study aims to explore strategies and evaluate the effectiveness of the digitalized demand supply chain for reducing zero stock incidents in PHC settings and how these reductions can improve the quality of care provided to patients.Method: A quantitative data collection on Zero stock incidents was conducted in all primary healthcare facilities over 24 months. Comparing the frequency of zero-stock items reports from before and after implementing the digitalized demand supply chain system.Result: The findings suggest that the new supply chain system has contributed to improving inventory management and reduced instances of zero-stock, ultimately enhancing the availability of essential supplies in PHCs.Conclusion: Quantitative analysis of zero stock reports over two years reveals that effective supply chain management and targeted interventions significantly reduce zero stock reports in PHC facilities