OAJOUR Open Access Journal Archives
Not a member yet
1994 research outputs found
Sort by
Cervical cytology screening in young rural girls between the age of 16-20 years
No full textAbstract
Background
Since the marriages are performed at an early age in the villages of rural India, the young girls are exposed to the early sexual exposure and subsequent prolonged sexual activity. These factors are instrumental in the development of precancerous lesions of cervix in the young girls.
Method
Rural cervical cancer screening program is in progress in the villages of western Lucknow. Since May 2013 and till date, a total of 189 camps has been organized and cytology done in 2980 women. The 118 of 2980 were in the group of 16-20 year and cytological findings obtained in them have been analyzed in relation to different risk factors of cervix.
Result
The incidence of squamous intraepithelial lesions of cervix (SIL) was found to be 15.2% (18 cases) in the 118 girls of the study group. The SIL was seen in the 50% of the 2 girls examined at 16 and 17 years but was low in the girls between 18 to 20 years. The SIL rate was maximum with nulliparous (19.3%), pain in lower abdomen (26.3%) and hypertrophied cervix (100%).
Majority of the young girls were nulliparous (infertile) while pain in lower abdomen was the most common symptom and hypertrophied cervix the only clinical lesion encountered in these 118 women.
Conclusions
The young girls in the rural population are at high risk of developing SIL as they are married at adolescent age and are subjected to early sexual exposure and subsequent prolonged sexual activity. The villagers should be taught about the ill effect of early marriage in the development of cervical cancer and should be counseled to avoid child marriage.
Key words
Adolescent girls, Cervical cancer in rural women, SIL, Nulliparous, Pain in lower abdomen
Neuroprotective Activity of Herbal Medicinal Products: A Review
No full textPlant-based drugs are among the earliest pharmaceuticals documented in even the most basic medical system's history. They are the most often used medicines due to their wide acceptance and general perception of their safer profile as compared to conventional drugs. Herbal medicines and products are gaining popularity around the world, not just as a caffeine-free alternative, but also as dietary supplements for low-calorie diets. In recent years, traditional medicine has gotten increased attention. Traditional medicine uses a range of herbs to cure neurodegenerative disorders such as Alzheimer's and other similar central nervous system issues. The term "neuroprotection" refers to strategies and systems for preventing neuronal injury in the central nervous system (CNS). Humans still have access to nature's medicines. Many important drugs are obtained from natural sources or based on the structural characteristics of naturally occurring substances, such as vincristine, artemisinin, and gentamicin. Traditional medicine has been documented to use a number of natural substances, usually plant extracts, for neuroprotective, memory-enhancing, and anti-aging objectives. Such plants include Panax ginseng, Ginkgo biloba, Bacopa monnieri, Curcuma longa, and Salvia officinalis. These plants were studied to see if the traditional claim was true, as well as to learn more about the mechanism through which they give neuroprotective advantages
Silk proteins and its biomedical and dental application: A Review: Silk proteins in medical and dental field
No full textSilk is a group of fibrous proteins that have been used for centuries in the textile industry and as surgical sutures. Silk, in addition to its unique mechanical properties, silk possesses other properties, such as biocompatibility, biodegradability, anti-bacterial properties, thermal stability, controlled degradation features, and ease of sterilization, ability to self-assemble make it a promising material for biomedical applications. Although silk forms only fibers in nature, synthetic techniques can be used to control the processing of silk into different morphologies, such as scaffolds, films, hydrogels, microcapsules, and micro- and nanospheres. Moreover, the biotechnological production of silk proteins broadens the potential applications of silk. With this background, this review describes silk proteins, their properties, synthesis, and uses.
Keywords: Silk, Silk proteins, Sericin, Fibroin, Denta
Silk proteins and its biomedical and dental application: A Review: Silk proteins in medical and dental field
No full textCompact Stars Admitting Noether Symmetries in Energy-Momentum Squared Gravity
No full textThis paper investigates the geometry of compact stellar objects through the Noether symmetry approach in the energy-momentum squared gravity. This newly developed theory overcomes the problems of big bang singularity and provides the viable cosmological consequences in the early time universe. Moreover, its implications occur in high curvature regime where the deviations of energy-momentum squared gravity from general relativity is confirmed. We consider the minimal coupling model of this modified theory and formulate symmetry generators as well as corresponding conserved quantities. We use conservation relation and apply some suitable initial conditions to evaluate the metric potentials. Finally, we explore some interesting features of the compact objects for appropriate values of the model parameters through numeric analysis. It is found that compact stellar objects in this particular framework depend on the model parameters as well as conserved quantities. We conclude that Noether symmetries generate solutions that are consistent with the astrophysical observational data and hence confirm the viability of this procedure
Impacts of Poynting–Robertson Drag and Dynamical Flattening Parameters on Motion around the Triangular Equilibrium Points of the Photogravitational ER3BP
No full textUsing an analytical and numerical study, this paper investigates the equilibrium state of the triangular equilibrium points L4, 5 of the Sun-Earth system in the frame of the elliptic restricted problem of three bodies subject to the radial component of Poynting–Robertson (P–R) drag and radiation pressure factor of the bigger primary as well as dynamical flattening parameters of both primary bodies (i.e., Sun and Earth). The equations of motion are presented in a dimensionless-pulsating coordinate system ξ−η, and the positions of the triangular equilibrium points are found to depend on the mass ratio μ and the perturbing forces involved in the equations of motion. A numerical analysis of the positions and stability of the triangular equilibrium points of the Sun-Earth system shows that the perturbing forces have no significant effect on the positions of the triangular equilibrium points and their stability. Hence, this research work concludes that the motion of an infinitesimal mass near the triangular equilibrium points of the Sun-Earth system remains linearly stable in the presence of the perturbing forces
Assessment of Near-Earth Asteroid Deflection Techniques via Spherical Fuzzy Sets
No full textExtensions of fuzzy sets to broader contexts constitute one of the leading areas of research in the context of problems in artificial intelligence. Their aim is to address decision-making problems in the real world whenever obtaining accurate and sufficient data is not a straightforward task. In this way, spherical fuzzy sets were recently introduced as a step beyond to modelize such problems more precisely on the basis of the human nature, thus expanding the space of membership levels, which are defined under imprecise circumstances. The main goal in this study is to apply the spherical fuzzy set version of Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS), a well-established multicriteria decision-making approach, in the context of planetary defense. As of the extraction of knowledge from a group of experts in the field of near-Earth asteroids, they rated four deflection technologies of asteroids (kinetic impactor, ion beam deflection, enhanced gravity tractor, and laser ablation) that had been previously assessed by means of the classical theory of fuzzy series. This way, a comparative study was carried out whose most significant results are the kinetic impactor being the most suitable alternative and the spherical fuzzy set version of the TOPSIS approach behaves more sensitively than the TOPSIS procedure for triangular fuzzy sets with regard to the information provided by our group of experts
A Quantized Hill’s Dynamical System
No full textIn this paper, we present a modified version of Hill’s dynamical system that is called the quantized Hill’s three-body problem in the sense that the equations of motion for the classical Hill’s problem are now derived under the effects of quantum corrections. To do so, the position variables and the parameters that correspond to the quantum corrections of the respective quantized three-body problem are scaled appropriately, and then by taking the limit when the parameter of mass ratio tends to zero, we obtain the relevant equations of motion for the spatial quantized Hill’s problem. Furthermore, the Hamiltonian formula and related equations of motion are also derived
An Analytical Computational Algorithm for Solving a System of Multipantograph DDEs Using Laplace Variational Iteration Algorithm
No full textIn this research, an approximation symbolic algorithm is suggested to obtain an approximate solution of multipantograph system of type delay differential equations (DDEs) using a combination of Laplace transform and variational iteration algorithm (VIA). The corresponding convergence results are acquired, and an efficient algorithm for choosing a feasible Lagrange multiplier is designed in the solving process. The application of the Laplace variational iteration algorithm (LVIA) for the problems is clarified. With graphics and tables, LVIA approximates to a high degree of accuracy with a few numbers of iterates. Also, computational results of the considered examples imply that LVIA is accurate, simple, and appropriate for solving a system of multipantograph delay differential equations (SMPDDEs)
Evaluation of Changes in Maternal Blood Sugar and Renal Function Tests during Gestational Period
No full textBackground and Objectives
The direct effects of altered maternal glucose metabolism and renal impairment from early pregnancy onwards with complications on mother as well as fetal growth and the risks of adverse birth outcomes. It is crucial to understand the biochemical changes to appropriately interpret common laboratory tests for evaluating renal disease and hyperglycemia in women during pregnancy. Thus, the study was focused to estimate the variability in blood glucose and renal functions as well as its association with BMI during pregnancy in Southern Terai of Province No. 2, Nepal.
Materials and Methods
Fasting blood glucose was determined by enzymatic (GOD/POD) method, Serum Urea by Urease-Bertholet’s Method, Serum creatinine by Jaffe’s Reaction Method, and Uric acid by Uricase method. All the biochemical parameters were analyzed using semi-automatic biochemical analyzer (Humalyzer 3500). Statistical analysis of the collected data was carried out using SPSS version 20. The p-value < 0.05 was considered statistically significant.
Results
The mean with standard deviation for fasting blood glucose (94.01+30.88; 99.71+23.97; 104.77+21.37) urea (23.22+7.89; 18.22+8.98; 20.64+9.09), creatinine (0.68+0.24; 0.65+0.20; 0.58+0.28), uric acid level with (3.14+0.93, 3.74+0.95, 3.95+0.85) was depicted in 1st, 2nd and 3rd trimester of pregnancy. Glucose and BMI were positively correlated and highly significant (r=0.191; p<0.01). BMI with urea was negatively correlated and was found to be highly significant(r= -0.196; p<0.01). Also, there was a negative correlation between BMI and Creatinine and was found to be significant (r=-0.132; p<0.01). But, the association of uric acid was positively correlated and statistically insignificant.
Conclusion
Blood glucose and uric acid gradually start increasing trimester-wise with the advancement of the gestational period. But, the mean urea level was decreased in the 2nd trimester as compared to the 1st and 3rd trimester. Also, small variation for creatinine level was found in different trimesters of pregnancy.
The association of Glucose, uric acid, and BMI were positively correlated and statistically insignificant whereas Urea and BMI was negatively correlated and highly significant. Also, there was a negative correlation between BMI and Creatinine and was found to be significant