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    Antepartum haemorrhage with respect to maternal and neonatal outcome

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    Background: Antepartum haemorrhage (APH) is defined as bleeding from or in the genital tract, occurring from 28 weeks of pregnancy and prior to the birth of the baby. Aim of Study to study the fetomaternal outcome in patients with APH. Methods: the present study was a prospective observational study undertaken in obstetrics and gynaecology department of Dr. Vikhe Patil Hospital, Ahmednagar during a period of 1 year from 1st October 2020 to 30th September 2021 in 65 cases of Antepartum Hemorrhage. Only patients with APH more than 28 weeks gestational age and willing to participate in study were included. Results: In the present study incidence of APH was 3.9%. 61% of the APH cases were placenta previa while 39% cases were of accidental haemorrhage. Majority of cases of placenta previa were of type 2 in this study. Out of the total accidental haemorrhage cases, 48% were revealed type and 48% were of mixed type in this study. With 4% being concealed type. Conclusions: Higher rates of neonatal intensive care unit (NICU) admission and stay  were seen with these complications. The study shows more respiratory distress syndrome, septicemia and jaundice in babies as outcome of APH . Keywords: Antepartum hemorrhage, Fetomaternal outcome, placenta previa, abruptio placenta

    Role of in-utero Neem leaf (Azadirachta indica) supplemented diet on some hematological parameters and glucose storage in offspring of Wistar rats.

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    Azadirachta indica (AI) Neem leaf is native of India which grows in most of tropical and subtropical countries. It tree has adaptability to a wide range of climatic, topographic and edaphic factors. This study explored the impact of AI supplementation during gestation on some haematological parameters and glucose storage in both offspring of Wistar rats. Eighteen pregnant female and 12 male Sprague-Dawley rats with a weight range of 140-180 grams were employed for this study and they were exposed to either a standard diet or AI supplementation (AIS). The pregnant rats were exposed to AIS up to birth (gestational AI supplementation) which comprised of both treated males (TM) and treated females (TF). Control rats with control diet was administered in analogous comparatively and this comprised of control male (CM) and control females (CF). During postnatal day 49, the rats were sacrificed and blood sample was obtained for assay of white blood cells (WBC), platelets (PLT), red blood cell counts (RBC), haemoglobin (Hb) and packed cell volume (PCV). Liver and gastrocnemius tissues were obtained for skeletal and hepatic glycogen assayed and intestinal and pancreatic α amylase and α glucosidase were determined from intestine and pancreatic tissues. WBC, PLT, RBC, Hb, PCV, alpha amylase, hepatic and skeletal glycogen increased significantly (p<0.05) in TM and TF with a remarkable decrease and increase in alpha glucosidase (p<0.05) in TM and TF respectively compared with CM and CF. It can be inferred from the present study that perinatal AI supplementation provides a substantial justification to its use in folk medicine as a hematopoietic plant and the increased glucose storage observed may not be unconnected with its role as an hypoglycaemic agent though the effect were more marked in female offspring compared with the male counterparts

    Evaluation of Mandibular Third Molars Impaction Related to Inferior Alveolar Nerve by Using Panoramic Radiography in Zliten City, Libya: A retrospective study

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    Abstract Objectives: This study investigates the relationship between impacted third molars and inferior alveolar nerve (IAN) by using panoramic x-ray. Material and Methods: A retrospective study was conducted at Assalam Dental Center in Zliten, Libya. We selected panoramic radiographic images of 65 patients (31 Female and 34 Male) between ages (17and 84 years) with 73 impacted mandibular third molars from the database of Assalam Dental Center that requires surgical extraction of their wisdom teeth. Results: Thirty-eight lower third molars out of the 73 impacted teeth were at high risk of damage to the inferior alveolar nerve with 52%, 11 impacted teeth with low risk to the inferior alveolar nerve, and 24 impacted teeth with no risk. Conclusion:  This digital radiographic study shows the importance of the preoperative radiographic in planning before the extraction of the lower third molars to avoid the risk of nerve damage

    Panic buying research: A systematic review of systematic reviews

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    Panic buying is an emerging and ever-evolving phenomenon during emergencies covering several perspectives of life and academic domains. However, it hasn’t got adequate attention reflected by a handfuls number of studies on it. We aimed to assess the systematic reviews that have been performed on panic buying. A search was conducted in PubMed, Scopus, Web of Science Core Collection, and Google Scholar on 30 June 2021, with the search terms “panic buying”, ”systematic review” using the Boolean function ‘AND’. The search was also supplemented by hand searching from the reference lists. We included only systematic reviews on panic buying. We identified and assessed five systematic reviews conducted on panic buying. A major focus in these reviews was psychological factors, precipitating reasons, and the inter-disciplinary nature of the phenomenon. The role of social media and social learning have been emphasized in the genesis of panic buying behavior. Panic buying has got recent attention as newer studies are coming out. However, further robust studies are warranted to understand this transdisciplinary construct and therefore, inter-sectoral collaboration in research is required to understand its genesis and prevention strategies

    The Story of Polycystic Ovarian Syndrome: A Challenging Disorder with Numerous Consequences for Females of Reproductive Age

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    As the name implies, polycystic ovarian syndrome (PCOS) is a chronic hormonal disorder that mostly affects women of childbearing age. However, symptoms suggestive of androgen overproduction and ovarian dysfunction have been identified. It's a huge public health issue. Women with PCOS are more likely to have co-occurring diseases, as well as various other long-term metabolic and health issues. Prevalence has risen steadily during the last decade, and it's expected to continue rising. Many health care providers and individuals might avoid it if they shared more information. Everything from the initial diagnosis to pathogenesis to effects and treatment options is still up for debate. The study's purpose is to provide a detailed analysis of current and upcoming diagnostic tools, as well as speculate on future strategies. We searched the Cochrane database for systematic reviews and meta-analyses, as well as the most recent international recommendations, to get a fresh look at PCOS

    Effects of Saccharum officinarum Molasses on Hematology and Hepatic Functions of Male Wistar Rats

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    Background: Sweeteners are a utile source of nourishment for cuisine preparation but are linked with the risk of occurrence of several diseases. Hence, the quest for healthier sweetening agents with lesser harmful effects cannot be ignored. Saccharum officinarum molasses, a natural nutritive sweetener, has become a popular substitute despite a dearth of knowledge on its healthiness. Aim: To assess the effects of Saccharum officinarum molasses on hematology, serum electrolyte, lipid profile, liver histology, and redox status of male Wistar rats. Methods: Blackstrap® Saccharum officinarum molasses (SOM) was fractionated to obtain Saccharum officinarum molasses methanol fraction (SOMMF) and Saccharum officinarum molasses aqueous fraction (SOMAqF). Seven groups (n = 5) of adult male Wistar rats received distilled water (Control); 1.0, 3.2, 10.0 g/kg SOMMF and 0.6, 2.0, 6.4 g/kg SOMAqF, respectively. Administrations were done daily via oral gavage for eight weeks. Full blood indices were determined with an automated hematology analyzer, serum electrolyte by monoliquid colorimetric test, and serum lipid profile using the enzymatic colorimetric test. Liver malondialdehyde and antioxidant levels were assayed by spectrophotometry. Liver histology was assessed using microscopy. Data were analyzed using ANOVA at p < 0.05 significance. Results: SOM increased liver catalase activity and serum levels of iron and potassium. It reduced serum levels of lipid profile, zinc and sodium ions, hemoglobin concentration, red blood cell count, packed cell volume, superoxide dismutase activity of the liver, and concurrently disrupted liver cytoarchitecture. Conclusion: Saccharum officinarum molasses adversely disrupted the hematological and hepatic functions of male Wistar rats

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