Journals Portal, Shahid Beheshti University of Medical Sciences
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Effects of GLUMA Desensitizer and Low-Level 980 nm Diode Laser on the Retention of the Metal Frames of the PFM Crowns Cemented by Self-adhesive Resin Cement (RelyX U200): Effects of GLUMA and 980nm diode laser on the retention of metal frameworks
Introduction: Sometimes, dentinal tubules are exposed to the oral cavity during the preparation of vital teeth for crowns, and patients show various signs of tooth hypersensitivity. Some treatments have been suggested for dental hypersensitivity after tooth preparation, such as low-level diode laser (980 nm) and GLUMA desensitizer. The pretreatment of dentin with desensitizers may affect retention. The aim of this study was to ascertain the effects of the 980nm Diode laser and GLUMA Desensitizer on the retention of the metal frames cemented by self-adhesive resin cement (RelyX U200).Methods: Thirty intact permanent maxillary first premolars were used in this study. After preparing teeth with 0.5 to 0.7 finishing line above CEJ, casting full metal crowns with a 5-diameter ring on the occlusal surface was done. Then the samples were divided into 3 groups: (1) Control Group (n=10), (2) 980 nm diode laser (n=10), and (3) GLUMA desensitizer (n=10). Frames were cemented with self-adhesive resin cement (RelyX U200) and the bond strength was measured by a universal testing machine. Data were analyzed by ANOVA and Tukey post hoc tests in SPSS version 25 (P<0.05).Results: Frame retention in the 980 nm diode laser group (40.90±27.07N) was significantly lower than the control group (138.17±40.81 N) and the GLUMA desensitizer group (318.59±56.31N) (P<0.05), and frame retention in the GLUMA Desensitizer group was significantly higher than the other groups (P<0.05).Conclusion: The GLUMA desensitizer has a positive effect and the 980 nm diode laser has a negative effect on the retention of frames cemented by self-adhesive resin cement (RelyX U200)
Comparing the Frequency of Migraine Headaches in Children With and Without Enuresis: Migraine Headache in Enuresis
Background and Aim: Nocturnal enuresis and migraine are common disorders amongchildren, each having a major impact on the health and life status of the children andtheir families. In several children, these two disorders have also been observed together.Accordingly, this study evaluates the relationship between migraine and nocturnal enuresisby examining the frequency of migraine in children with nocturnal enuresis.Methods: In this analytical cross-sectional study, the experimental group includes childrenwith nocturnal enuresis, who were diagnosed by a pediatric nephrologist. The controlgroup is comprised of children without nocturnal enuresis. In both groups, the frequencyof migraine headaches diagnosed by pediatric neurologists was checked and finally, thefrequency obtained in the two groups was compared. The sample size was 47 people foreach group. Information analysis was done through analytical statistics, including tables andstatistical charts and their analysis. Independent t-test, the chi-square test, the Fisher test, andif necessary, equations were used to analyze the non-parametric data.Results: The distribution of frequency between gender and nocturnal enuresis was the samein two groups (57.4% male and 42.6% female). Also, the mean age in the patient categorywas 7.6±2.3 years and in the healthy category was 8.3±2.6 years. The frequency distributionbetween having migraine, migraine with aura, the number of times experiencing headache,and family history at the time of admission were the same in the two groups.Conclusion: In conclusion the frequency of migraine, migraine with aura, the number oftimes experiencing headache, and family history of migraine were the same in the two group
The effectiveness of self-compassion on the sleep quality and life quality of mothers with children with attention-deficit/hyperactivity disorder
Background: This study aimed to investigate how self-compassion affected the quality of sleep and overall well-being of moms whose children had been diagnosed with ADHD (Attention Deficit Hyperactivity Disorder).
Methods: This was a quasi-experimental study. Thirty mothers were randomly divided into an experimental group (15 participants) receiving self-compassion training and a control group (15 participants) receiving no intervention. Data collection tools included the Pittsburgh Sleep Quality Index, the WHO Quality of Life questionnaire, quantitative electroencephalography, and a self-compassion protocol. Data analysis was performed using SPSS-24, with descriptive statistics and multivariate analysis of covariance (MANCOVA).
Results: Results showed no substantial differences between groups in the pre-test phase. However, post-test results revealed significant improvements in the experimental group. Self-compassion interventions significantly enhanced sleep quality (F=45.64, P<0.01), life quality (F=275.12, P<0.01), and alpha wave activity (F=176.64, P<0.01). These improvements highlight the effectiveness of self-compassion training in reducing stress and anxiety, leading to increased satisfaction and calmness.
Conclusion: Self-compassion-based programs can serve as a beneficial approach to enhancing sleep quality and overall life quality in mothers of children with ADHD. This research underscores the potential of self-compassion interventions in promoting mental well-being and improving physiological and psychological outcomes
Translation, Cross-Cultural Adaptation, Validity, and Reliability of the Persian Version of the Upper Limb Functional Index
Introduction: The Upper Limb Functional Index (ULFI) is a patient-reported outcome measure (PROM) designed to evaluate the functional status and level of participation of individuals with upper limb musculoskeletal disorders (ULMSDs). The purpose of this study was to translate the original ULFI into Persian (ULFI-Pr) and assess the psychometric properties of ULFI-Pr in Iranian individuals with ULMSDs. Materials and Methods: This cross sectional study was conducted in two stages based on standard guidelines. The ULFI was cross-culturally adapted through double forward and backward translations, and then its psychometric properties were validated. Participants (n=150) with various upper limb conditions for >12 weeks completed the ULFI and the Disabilities of the Arm, Shoulder, and Hand (DASH). Internal consistency and test-retest reliability were determined using Cronbach’s Alpha and the Intraclass Correlation Coefficient (ICC). The full sample determined internal consistency, concurrent criterion validity, construct validity, and factor structure; a subgroup (n=30) determined reliability at 14 days interval. Results: The original ULFI was translated and cross-culturally adapted into Persian with only minor wording changes. The ULFI-Pr demonstrated high internal consistency (α = 0.93) and test-retest reliability (ICC=0.92). The correlation between ULFI and DASH was high (r = 0.71) and P<0.001). Construct validity was examined through exploratory factor analysis (EFA) using Maximum Likelihood Extraction with Promax rotation. The EFA demonstrated a one-factor structure that explained 38.2% of total variance. No floor or ceiling effects were observed. Conclusion: The ULFI-Pr can be considered a region-specific, single-factor structure PROM for the evaluation of ULMSDs for clinical and research purposes in Persian language populations
Validation of a Stability-Indicating Analytical Method Development for Simultaneous Estimation of Sodium Phenylbutyrate and Taurursodiol in Bulk and Formulation Using UPLC Method: Analytical Method Development for Simultaneous Estimation of SPB and TRS in Bulk and Formulation by UPLC
Sodium phenylbutyrate (SPB) and taurursodiol (TRS) are commonly used in combination therapy to treat amyotrophic lateral sclerosis, popularly known as Lou Gehrig's disease. Using Ultra-Performance Liquid Chromatography, a stability-indicating analytical approach was designed and validated to evaluate SPB and TRS in bulk and dosage form simultaneously. Acquity UPLC BEH Shield RP-18 column (50 x 1.0 mm, 1.7µm) was used for the chromatographic separation. Next, a mobile phase was added at a 0.5 ml/min flow rate. The mobile phase included acetonitrile and 0.1% perchloric acid (20:80) v/v. Analytes were found at a wavelength of 287 nm with a photodiode array detector. An autosampler injected a five μl sample into the column, which was kept at 25 o C. SPB and TRS eluted values were 0.522 min and 1.311 min, respectively. For SPB and TRS, linearity was determined within the range of 75–450 μg/ml and 25–150 μg/ml, respectively. The method's robustness was evaluated by purposefully changing parameters like flow rate, detector wavelength, and column temperature. Additionally, research on forced degradation in the presence of different stress conditions, such as heat, peroxide, acid, and ultraviolet light, showed that the approach could identify stable materials. In conclusion, it was found that the developed analytical method for simultaneously determining SPB and TRS in bulk and their formulation was more precise, reliable, and specific
Adenosine and High-intensity Interval Training as Potential Therapies on Free Fatty Acids and Metabolic Factors in High-fat Diet-Induced Obesity in Male Wistar Rats : Adenosine and HIIT on Metabolic Factors
Obesity, caused by an inequality between energy production and consumption, is characterized by lipid accumulation in adipose tissues. Currently, around 650 million adults and roughly 340 million children and adolescents (aged 5-19 years) are affected by obesity. This condition tends to be more common among women and older populations. It is imperative to develop uncomplicated therapeutic approaches to prevent obesity-related metabolic diseases in conjunction with lifestyle modifications. Forty-three rats were randomly divided into five groups: 1. normal diet (ND), 2. High-fat diet (HFD), 3. HFD + adenosine, 4. HFD + High-intensity interval training (HIIT) + adenosine, and 5. HFD + HIIT. Gene expression of CGI-58, HSL, and AMPK in subcutaneous adipose tissues and serum level of glucose, insulin, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), free fatty acid (FFA), and lipid profile (Triglyceride (TG), Total cholesterol (TC), Low density lipoprotein (LDL), High density lipoprotein (HDL), and Very low density lipoprotein (VLDL)) were assessed. The rats were fed HFD-induced obesity for 13 weeks. Following, adenosine 0.2 mg/ml/kg and 0.4 mg/ml/kg, as well as HIIT, were administered over 12 weeks. CGI-58, HSL and AMPK gene expression showed significant expression in all groups. HFD+HIIT+adenosine, HFD+adenosine, and HFD+HIIT groups significantly increased all genes. Conversely, FFA and glucose serum levels were significantly reduced in intervention groups. Insulin had higher serum levels in ND, HFD + adenosine, and HFD+HIIT groups, and adenosine caused decreased glucose. Also, favorable effects of HIIT and adenosine on lipid profile were observed. HIIT and adenosine can affect lipid metabolism, improve insulin resistance, and increase lipolysis in adipose tissue. Furthermore, adenosine can boost the effect of HIIT on gene expression, triggering lipolysis to prevent obesity
بررسی انتقادی محتوای برنامه و خدمات عرصۀ سلامت روان در نظام مراقبتهای اولیۀ بهداشتی با روش واسازی و تحلیل انتقادی
خلفية البحث وأهدافه: تعتبر السلامة النفسیة جزءاً لا یتجزأ من السلامة والرفاه الفردي والإجتماعي. إنّ وتیرة انتشار الأمراض في العالم توحي بأنّ المشاکل والتحدیات المتعلقة بالسلامة النفسیة تعتبر العامل الثاني في انتشار الأمراض والعجز الصحي. اما بالنسبة للبلاد (إیران) یمکن القول أنّ البلاد خطت خطوات جبارة في نظام العنایة الصحیة علی مستوی البلاد ونجحت في تعمیم القطاع الصحي والضمان الإجتماعي والسلامة النفسیة. والشعب یثق بشکل کبیر في النظام الصحي ویتعامل مع برامج ومشاریع نظام الصحة النفسیة. کما أنّ هناك الکثیر من الخدمات التي یقدمها النظام الصحي لعدد هائل من المواطنین. ولهذا تسعی هذه الدراسة لتقییم دقیق للخدمات والبرامج الخدمیة التي یقدمها النظام الصحي في البلاد.
منهجية البحث: المنهج الذي اعتمدت علیه الدراسة هو المنهج التفکیکي مع الترکیز علی فهم المحتوی بدل الوصف ونقد هذه البرامج نظریاً وبنیویاً. ولکي تنجح الدراسة في البحث بادر الباحثون بجمع المحتوی النصي لقسم السلامة النفسیة في مکاتب السلامة النفسیة، والإجتماعیة، ومراکز إعادة تأهیل المدمنین الموثوقة لدی وزارة الصحة؛ وقد تضمنت 1210 صفحة تم استخراج وتجمیع المفاهیم الأساسیة منها. وفي المرحلة الأخیرة قام الباحثون باستخراج المفاهیم الأکثر أهمیة لدراستها وتحلیلها بشکل جذري بغیة استخراج النتیجة الأکثر دقةً. إنّ مولفي البحث لم یشیروا إلی أيّ تضارب في المصالح.
المعطیات: اکدت النتائج التي حصل علیها الباحثون أنّ هناك مواطن ضعف في نظام الصحة مثل غیاب التناسق الثقافي بین المحتوی وثقافة الأفراد، وعدم الإهتمام بالصحة الروحیة، وقِدَم المضامین وغیاب الإرجاع إلی المصادر المعتبرة.
الاستنتاج: نظراً لتوفّر مصادر علمیة ونماذج محلیة ناجحة، یجب إعادة النظر في برامج النظام بهدف الإرتقاء بمستوی الخدمات الصحیة والسلامة النفسیة في المجتمع والتأکید علی الوقایة وتوقي الأمراض بدل علاجها.Background and Objective: Mental health is considered an inseparable part of individual and social health and well-being. The prevalence of diseases in the world shows that mental health problems are the second most debilitating factor in health. The primary health care system in the country has a very successful history in generalizing and developing mental health services. People are easily connected to this system and cooperate and participate to a large extent for the implementation of mental health programs. A large number of service packages are implemented in the country. For this reason, it is necessary to carry out a detailed review and evaluation of the content of services and care packages.
Methods: In this article, the deconstruction method was used with an emphasis on the deep understanding of the contents instead of describing them and their theoretical and fundamental criticism. For this purpose, all the textual content of the Mental Health Department of the Mental and Social Health and Addiction officeof the Ministry of Health, which include 1210 pages, was analyzed and the main concepts were compiled and summarized. Finally, the extracted fundamental concepts were discussed and conclusions were drawn. The authors of the article have reported no conflicts of interest.
Results: Low level of cultural compatibility, neglect of spiritual health, outdated materials and lack of references to reliable sources were identified and confirmed.
Conclusion: It is essential to conduct a fundamental review based on scientific resources and indigenous models, aiming to enhance the mental health of the community with a preventive approach in the packages.سابقه و هدف: سلامت روان بخشی تفکیکناپذیر از سلامت و رفاه فردی و اجتماعی قلمداد میشود. روند شیوع بیماریها در جهان نشان میدهد که مشکلات سلامت روان دومین عامل ناتوانکنندۀ سلامتی است. نظام مراقبتهای اولیۀ بهداشتی در سطح کشور پیشینۀ بسیار موفقی در تعمیم و توسعۀ خدمات سلامت روان دارد. مردم به شبکۀ بهداشت اعتماد دارند و بهراحتی به این نظام پیوند میخورند و تا حد زیادی برای اجرای برنامههای بهداشت روان همکاری و مشارکت میکنند. بستههای خدمت به تعداد بسیار زیاد در کشور اجرا میشود. به همین دلیل این پژوهش با هدف نقد و ارزیابی دقیق از محتوای بستههای خدمت و مراقبت صورت گرفته است.
روش کار: در این مقاله از روش واسازی با تأکید بر درک ریشهای و عمیق محتواها بهجای توصیف آنها و نقد نظری و بنیادی آنها بهطور جسورانه استفاده شده است. بدین منظور تمام محتوای متنی گروه سلامت روان دفتر سلامت روان، اجتماعی و اعتیاد وزارت بهداشت که مشتمل بر 1210 صفحه بود بررسی شد و مفاهیم اصلی تدوین و جمعبندی شد. در مرحلۀ آخر نیز مفاهیم بنیادین استخراجشده به بحث گذاشته شد و نتیجهگیری انجام پذیرفت. مؤلفان مقاله هیچگونه تضاد منافعی گزارش نکردهاند.
یافتهها: بر اساس نتایج بهدستآمده، تطابق پایین فرهنگی، بیتوجهی به سلامت معنوی، قدیمیبودن مطالب و نبود ارجاع به منابع معتبر محرز گردید.
نتیجهگیری: ضروری است بر اساس منابع علمی و الگوهای بومی، بازبینی اساسی با هدف ارتقای سلامت روان جامعه با رویکرد پیشگیرانه در بستهها انجام گیرد
The Effectiveness of Reality Therapy on Anger Rumination, Depression, and Quality of Life among Individuals Bereaved Due to COVID-19
Background and Aim: This study aimed to investigate the effectiveness of reality therapy on anger rumination, depression, and quality of life among individuals bereaved due to COVID-19.
Materials and Methods: The research method was a quasi-experimental design with pre-test, post-test, and follow-up phases, including a control group. The statistical population comprised all first-degree survivors of COVID-19 victims in Nishapur city. A total of 30 participants were selected through purposive sampling and were then randomly assigned to two groups of 15: experimental and control. The experimental group underwent an intervention of reality therapy over 8 sessions, each lasting 1.5 hours, while the control group received no intervention. Data were collected using the Anger Rumination Scale (ARS), the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF), and the Beck Depression Inventory (BDI-II). The data were analyzed using multivariate covariance analysis (MANCOVA) via SPSS24 software.
Results: The results of Bonferroni post-hoc tests comparing time effects indicated that the differences in the mean scores of qualities of life, anger rumination, and depression between the pre-test and post-test phases, as well as between the pre-test and follow-up phases, were statistically significant. However, the differences in mean scores between the post-test and follow-up phases were not significant (P > 0.05).
Conclusion: Accordingly, reality therapy was effective in improving anger rumination, depression, and quality of life among survivors of COVID-19 victims, and this effectiveness persisted during the follow-up period. Psychologists and counselors can use reality therapy to enhance anger rumination, depression, and quality of life among individuals bereaved due to the COVID-19 pandemic
The Impact of Vital Pulp Therapy on Normal Root Development in Immature Teeth: A Case Report
Vital pulp therapy is one of the least invasive and simplest and most economically acceptable treatment alternatives for immature teeth with pulpitis. The success rate of this treatment, with calcium silicate-based cements, ranges from 85% to 100%. Vital pulp therapy prevents the development of apical periodontitis and promotes normal root development, allowing the tooth to remain in the dentition and perform its functions. The patient was a nine-year-old boy with pain on chewing and a positive response to cold. The panoramic radiograph showed an immature permanent lower molar with deep caries. Partial pulpectomy and root pulp sealing with pre-mixed calcium silicate-based cement were performed under aseptic conditions. The absence of symptoms and the formation of roots with apical sealing were successfully achieved and observed by follow-up and radiographic control, making this treatment a viable option for immature teeth with pulpitis
Combination of Different Laser Wavelengths as a Treatment Strategy for Maxillary Osteonecrosis: A Case Report: Laser therapy as treatment for maxillary osteonecrosis
Introduction: Osteonecrosis causes the death of bone tissue due to insufficient blood flow, which bdisrupts the supply of oxygen and nutrients, compromising the structural integrity of the bone. The jaws are particularly vulnerable due to their high bone turnover and vascularization. This study aimed to present the complex case of a patient diagnosed with maxillary osteonecrosis associated with osteomyelitis, treated exclusively with laser therapy.
Case Report: We present the case of a 62-year-old male patient with maxillary osteonecrosis associated with osteomyelitis, manifested by an oroantral fistula located in the upper jaw. The treatment consisted of various laser therapy modalities, starting with the surgical phase on hard tissue for the excision of the necrotic bone (Er,Cr:YSGG 2780 nm laser), followed by photodynamic therapy (650 nm diode laser) for wound disinfection and intravascular laser irradiation of blood (ILIB) therapy (880 nm diode laser) in each session.
Conclusion: The combination of different laser wavelengths was effective for the treatment of osteonecrosis