International journal of health sciences
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Psychometric properties of the research attitude index (IAI) in a population of Peruvian university students
Get PDFThe aim of the study was to evaluate the psychometric properties of the Research Attitude Index (IAI) in a sample of Peruvian university students. The sample consisted of 1188 students, 56.6% of whom were female and 43.4% male, ranging in age from 17 to 60 years old. After the factor analyses (exploratory and confirmatory), the three factors or dimensions of the instrument were consolidated, and reliability was calculated using Cronbach's alpha, finding good internal consistency. In addition, the Kaiser-Mayer-Olkin (KMO) validity was found, all values being adequate to verify the psychometric quality of the instrument
Assessment of estrogen receptor marker and smooth muscle actin marker in oral pyogenic granuloma
Get PDFSoft tissue enlargement of the oral cavity usually existent a diagnostic challenge because many group of pathologic activity can cause these lesions. An enlargement may display a variation of normal anatomic structure, cyst, inflammation, developmental anomalies and neoplasm. These lesions included a group of reactive hyperplasia which arises in response to recurring; chronic tissue injury that provokes vigorous or extreme tissue repair response .so pyogenic granuloma is one of the many common entities in charge of soft tissue enlargement. Objective: The current study aimed to detect the immunohistochemical expressions of ER and alpha smooth muscle actin (α-SMA) for lobular capillary hemangioma (pyogenic granuloma). Material and Methods: fifty cases of confirmed diagnostic pyogenic granuloma were subjected to immunohistochemically assessment by using ER marker and Smooth Muscle Actin marker. Result: The immunohistochemically finding appeared that all 50 cases were positive for SMA marker while only 14 cases were positive for ER marker. So there is no significant difference between ER marker in relation to clinical parameters (age, gender and location) and intensity
PBMC miRNA in diagnosis of rheumatoid arthritis: A miRNA expression analysis study
Get PDFBackground and objective: RA is an autoimmune disorder mediated by autoantibodies. miRNAs have been shown to negatively regulate protein translation via an antisense RNA-RNA interaction. Altered miRNA expression has been well established in autoimmune diseases. In this study, the expression of four microRNA was analysed. Also, correlation between microRNA and immunological markers was examined. Method: RNA was isolated from PBMC obtained from 100 RA patients and age-gender matched healthy controls. Levels of mature miRNA of miR146a, miR155a, miR499 and miR124a were detected using real time PCR. Downstream cytokine was analysed using ELISA from R&D systems. Result: Real time PCR reveals that the expression of miR-146a, miR-155a, miR-499 in PBMC was found to be down regulated in RA patients when compared to the controls by fold change of 0.15, 0.69 and 0.04 respectively whereas, expression of miR124a was found to be low to detect. Expression of TNF- alpha upregulated (p-value=0.09) and IL6 was found to be insignificantly down regulated in patient. miRNA 155a was found to be in significant negative correlation with rheumatoid factor (r= -0.210; p=0.038). 
Formulation and evaluation of herbal body lotion: A review
Get PDFThis article is all about the requirement of standardization and the composition of herbal product in day to day life. Composition of herbal products will give ever best effect in our daily life as the composition of any single and individual product. The only motive-behind to choose the mixture of herbal product was to bring true upon the effectiveness of these formulation without any side-effects. Comparision include organoleptic and physio-chemical character such as viscosity, ph, spreadibilty, moisture free body after use
Design of intelligent IoT for smart healthcare monitoring system using optimal neural network (IONN) model
Get PDFOne of the most important aspects of human life is health. Every society is paying more attention to and implementing technology in the areas of health and healthcare. In the healthcare sector, Artificial Intelligence (AI) is frequently employed to deliver quick and reliable results. Early disease predictions assist doctors in making timely decisions to save patients' lives. The Internet of Things (IoT) is assisting AI applications in healthcare by acting as a catalyst. The data of the patients is gathered by IoT sensor, and the data is analysed using machine learning algorithms. The IONN model, an innovative and intelligent healthcare monitoring system based on modern technologies such as the IoT, optimization techniques, and machine learning, is introduced in this study to detect various diseases early and precisely. For people who reside in rural places, this system gives a low-cost solution. The accuracy of the proposed IONN model has enhanced by 4% to 15% when compared to existing approaches. Furthermore, as compared to ANNs that use the BPN algorithm, the IONN model reduces the overall training time by 15% to 52%. 
Herbal hair oil: A review
Get PDFBeauty and cosmetic concept is as ancient as mankind and civilization. Cosmetics play a vital role in human life. Herbal cosmetic is one of the most effective areas of cosmetic technology. Herbal cosmetics are developed by the coalition of bioactive ingredients and pharmaceutical products. Herbs are used for beautification purpose of body, preparation of cosmetics, flavouring and colouring agent. Hair plays a vital role in personality of human and we use a lots of cosmetics product for the care of hair. The study aims reviewing the importance of herbal oil and their use in the common hair problem such as baldness, hair fall, hair dryness, dandruff etc. Various beauty and cosmetic products are used which contain herbs to give young and charming look. Various herbal ingredients are used in herbal hair formulation; they provide essential nutrients such as vitamins, antioxidant, etc. Herbal hair oil has been widely used for nourishment of hair and for the protection of hair from hair fall and hair damage. Now a day’s side effect is a major problem after using any beauty product due to which herbal products are preferred because of having less probability of any types of side effects
Employee creativity and ability, motivation and opportunity approach through moderation effect learning culture in it industry: An empirical research
Get PDFThis article aims to assess the impact of employee creativity and ability, motivation and opportunity on learning culture of IT employees. The article applies Reliability Analysis, Descriptive Statistics, EFA and Regression on a sample of IT employees 357. A usual of 18 items of Employee creativity and AMO converted into four factors. The current study proposes a model of Employee Creativity and AMO approach through moderation effect learning culture of IT employees. The research found that Employee creativity, ability, motivation and opportunities are impacting significantly the learning culture of IT employees. The present research explored the effect of creativity and AMO on the learning culture of IT employees concluded that motivation had the highest impact on learning culture surveyed by creativity, ability and opportunity
Description of antiendotoxic immunity immunological properties in children diagnosed with microbe etiological diseases
Get PDFThe aim of the study was to determine the titer of antibodies against gram-negative bacterial endotoxins in diseases of various microbial etiology in children, to assess its diagnostic value and to evaluate the immunological properties of antiendotoxic immunity. It was found that the percentage of seropositive sera to GShPB antigens was convincingly higher in children with MEK and IID than in healthy children. The percentage of detection of antitoxin antibodies depended on the type of microorganism. The most important in YID were Escherichia coli i Pseudomonas aeruginosa, and in MEK were Escherichia coli. In terms of the intensity of antitoxin antibody formation, MEK differed sharply from other groups. While “medium” and “high” titers were detected mainly in the CEC, only “low” titers were detected in healthy and YID-observed children. Determination of the intensity of antibody formation against GShPB endotoxins at "medium" and "high" titers is recommended as an additional diagnostic and prognostic criterion in the diagnosis of MEC
Lipid nanocarrier system of perinodopril for enhancement of bioavailability
Get PDFPerinodopril comes under BCS class II drug (low solubility/high permeability) which shows variable absorption pattern due to solubility limitation. Therefore, nanostructured lipid carrier (NLC) of Perinodopril was developed which is suitable for drug with high log P value as it offers the advantage of high drug entrapment and loading capacity to lipophilic drugs. Tween 80 and Poloxamer 188 were reportedly P-gp efflux inhibitors which would be an added feature to the property of Perinodopril -NLC thus enhancing drug availability across intestine. So the objective of the current work was to evaluate the NLC of perinodopril formulation and to evaluate the same. The invivo estimation of the activity was carried out on Albino wistar rats that are maintained under room conditions and the formulation was investigated for the Pharamcokinetic and pharmacodynamic paramteres in rat plasma. Also they were tested for their stability invitro. Results show that the nano particles measured as 0.207nm in size. The invitro drug release studies suggest that the formulations were releasing the drug in controlled fashion during 23 hrs. Stability studies proves the drug is very stable in the formulation
Description of the level of the effect of gene-modified soy on normal microflora in the experience
Get PDFThe aim of the study was to determine the effect of GM-soy on the microbiocenosis of white colonized rats in the experiment. In the normal microflora of the colon of rats fed with GM-free soybeans, it was found that different quantitative differences were different from those of intact laboratory animals Bifidobacterium spp (1.28-fold decrease), Lactobacillus spp (1.53-fold decrease), Enterobacter spp, and Proteus spp (4.1). and an increase of 6.25 times). This did not indicate the development of complete dysbiosis, as no group differences between Escherichia colilactosanegative and lactose-positive strains were identified, Symptoms of dysbiosis were poorly developed in GM-free soybeans (DI I), and dysbiosis symptoms were more pronounced in GM-soy-fed soybeans (DI II)