International journal of health sciences
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Effectiveness of integrated approach of emotional first aid and life skills training on psychological distress among adolescent students
Full text linkOur country is recently known as the most populated country on the planet, and this only adds to the already neglected mental health epidemic of “Depression” and “Psychological Distress”. Psychological distress is a state of suffering that happens emotionally when a person feels completely devoid of emotions and lacks complete interest in previously pleasurable activities. This research paper focuses on how life skills training and emotional first aid can help address distress and emotional stressors daily. The experiment aims to provide training on emotional first aid and life skills to students, thereby reducing the levels of psychological distress among students. For this, a sample of 350 students was taken and further divided into experimental and control groups of 60 each. The Depression Anxiety Stress Scale was used to determine the levels of psychological distress, here correlation method was used to test the effectiveness of variables. The results of the study indicated that Life skills training and psychological distress training have reduced the levels of Psychological distress among adolescent students. There was a significant impact of the integrated approach of life skills training and emotional first aid on psychological distress
A review on wound healing properties of Tinospora Cordifolia
Full text linkWound healing is the body’s natural process of regenerating dermal and epidermal tissue. The healing cascade is activated when platelets come into contact with exposed collagen leading to platelet aggregation and the release of clotting factors resulting in the deposition of a fibrin clot at the site of injury. . Tinospora Cordifolia (Menispermaceae) Synonyms: Giloe, Gurcha, Gulvel, Gilo. It contains Alkaloids, Glycosides, Steroids, Sesquiterpenoids, Aliphatic compound, and Essential oils, Mixture of fatty acids and Polysaccharides. Pharmacological Activities: Adaptogenic activity, Immunomodulatory Activity, Anticancer Activity, Anti-Inflammatory Activity, Antimalarial Activity, Anti-Allergic Rhinitis Activity, Wound Healing Activity, Antioxidant Activity, Hepatoprotective Activity, Anti-Diabetic Activity, Anti-Osteoporotic Activity, Radio-Protective Activity, Cardio-Protective Activity. The review article highlight the effect of the extract of tinospora cordifolia of the wound when is given in dose range of 200 – 250 mg/kg
Integrating psychological interventions into holistic management of chronic respiratory diseases: Update review
Full text linkChronic Respiratory Diseases (CRD), such as asthma, interstitial lung disease, and chronic obstructive pulmonary disease (COPD), have a significant negative influence on a patient's physical and mental health. Stress, anxiety, and depression are common psychological injuries that worsen lung function, and increase mortality, exacerbations, and healthcare utilization in patients with chronic respiratory disease (CRD). Pulmonary rehabilitation is a gold standard non-pharmacological management for CRD—where care delivery strategies are based on a bio-psycho-social model of integrated therapies. However, there are still issues since there are global differences in the way programs are designed and implemented, and there are no standardized psychological assessments or therapies available for patients with CRD. This review critically examines the challenges in standardizing pulmonary rehabilitation programs and the lack of health psychological assessment or interventions for patients with CRD. Additionally, it suggests necessary updates to respiratory physiotherapy curricula with the neuroscience of breathing in clarifying the relationship between psychological factors and inflammation in CRD. The review calls for an urgent need for increased global research funding to enhance psychological therapies as integrated respiratory care management and improve outcomes for patients with CRD
Patient out-of-pocket expenditure in primary care comparing high income, middle income and low-income countries
Full text linkBackground: Out-of-pocket health expenditures (OOPHE) in primary care can pose a significant financial burden on individuals and households, particularly in low- and middle-income countries. Understanding the factors influencing OOPHE is crucial for developing effective policies to improve healthcare access and affordability. Objective: This systematic review aimed to identify and analyze the factors influencing OOPHE in primary care settings across high-, middle-, and low-income countries. Methods: A comprehensive search of electronic databases was conducted to identify relevant studies. Included studies were assessed for quality and data were extracted to identify key factors influencing OOPHE. Results: Demographic characteristics, socioeconomic factors, healthcare utilization, system factors, and cultural factors were all found to influence OOPHE. Lower income levels, limited insurance coverage, frequent healthcare utilization, and higher disease severity were consistently associated with higher OOP costs. Conclusion: The findings highlight the significant burden of OOP expenditures on individuals and households. Policymakers should prioritize strategies to expand health insurance coverage, improve access to primary care services, negotiate lower prices for healthcare goods, and address underlying socioeconomic factors. Further research is needed to explore the impact of specific interventions and the role of cultural factors in shaping OOP expenditures
Evaluation of the functional status of post caesarean women with low back pain using Psoas major exercise: A randomized clinical trial
Full text linkLow back pain and functional limitations have been commonly reported in postnatal women who underwent a cesarean section (C-section). Despite the understanding that the Psoas major muscle, an important lumbar spine stabilizer, is critical in the treatment of low back pain, only limited studies on the benefits of Psoas major exercise intervention in postpartum C-section women prevail. Therefore, the present study aims to determine the influence of psoas major exercise in postnatal cesarean women with low back pain, and functional impairments. 60 women who had C-section deliveries participated in the present prospective randomized study either in the control group A (n = 30) or in the interventional group B (n = 30). The Roland-Morris Low Back Pain and Disability Questionnaire (RMQ) and NPRS (Numerical Pain Rating Scale) were utilized as standardized assessment tools and the outcome measures revealed that intervention with designed Psoas major exercises in postnatal C-section women significantly alleviated low back pain and improved functional status (p<0.001). The study results, thus clearly demonstrate the beneficial influence of Psoas major exercise in postnatal C-section women, and emphasize the need for further large cohort studies
Knowledge on water, sanitation and hygiene (WASH) practice among cyclone Yaas affected people of Shyamnagar, Satkhira district : Knowledge on WASH practice among cyclone affected people
Full text linkProper disposal of all waste as well as control of the carriers of communicable diseases. Objective: The aim of the present study was to assess the knowledge on water, sanitation and hygiene practice among cyclone Yaas affected people of Shyamnagar, Satkhira district. Methodology: A cross sectional study was conducted in the Department of public health, North South University, Dhaka. The duration of the study was from July 2021- September 2021. People of Koikhali, Gabura , Munshiganj union of Shyamnagar were the study population. After data collection and processing, all statistical analysis was done by SPSS software windows version 26. Result: 384 people from Shyamnagar were interviewed with a questionnaire. 84.11% respondents were utilized tube well water. Only 16% respondents were utilizing filtered water for drinking. 58.07% respondents were used sanitary type of latrine. 84.11% respondents had the knowledge about hand washing technique. , hapazardly throwing was the approach used by 60.94% of respondents to dispose of solid waste products. Before eating, 67.97% of respondents just washed their hands with water. 59.11% of respondents just washed their hands with water after defecation. Of those surveyed, 64.06 percent routinely washed their clothes.71.86% respondents were utilized footwear regularly before using latrine. 
The role of pharmacogenomics in personalized medicine: A focus on drug metabolism
Full text linkBackground: The conventional model of drug treatment may involve set protocols of drug use and not the currently variegated pharmacology patterns due to mutations in drug metabolism enzymes. But recent innovations in pharmacogenomics have provided new insight on feeds and processing of drugs through genetic and environment components that present a more divergent view of treatment. Aim: The purpose of this study is to understand drug metabolism specificity in the framework of individualized medicine and its potential to enhance the efficacy and safety of a drug due to genetic and lifestyle differences. Methods: A literature search was performed to compare the effects of genetic variations and environment as to drug metabolism. The research also focuses at how the pharmacogenomics testing is used in developing the custom drug therapies. Results: major impact in the rate of metabolism of drugs along with their effectiveness and toxicity. Of course, assessing health-promoting behaviours that include diet and physical activity, or the lack of thereof, as well as others, can strongly impact therapeutic success. Conclusion: Potential for manufactured Meal is its ability to highlight the vests in drug metabolism that are crucial for finding personalized treatments. 
Apparition of germline mutation c.1395-1397del of MUTYH in Algerian consanguineous family with colorectal cancer
Full text linkMUTYH is a glycosylase that removes adenine opposite 8-oxoguanine (OG) during base-excision repair of DNA. Variants of MUTYH defective in functional activity lead to MUTYH-associated polyposis (MAP), autosomal recessive predisposition to colorectal cancer (CRC). MAP combines clinical features with other hereditary CRC syndromes, and exhibits phenotypic overlap, particularly with Lynch syndrome (LS). To determine the impact of MUTYH mutations in colorectal adenomas and cancer susceptibility, this prospective objective screens the MUTYH gene in seventeen Eastern Algerian families with clinically suspected LS but without mismatch repair (MMR) mutations. Methods: We examined the presence of the mutations in the probands and their relatives using direct sequencing of the entire coding region of the MUTYH gene. Results: The biallelic and monoallelic pathogenic MUTYH mutations, c.1395_1397del, were discovered in a consanguineous family with CRC and gastric cancer as a novel finding in our Eastern Algerian population. Conclusion: High rates of consanguinity in Algerian population increase the risk of CRC caused by biallelic mutations in the MUTYH gene. In our families, the LS and MAP phenotypes might coexist. 
Modern consumption pattern of social networking sites and its impact on the mental health of adolescents
Full text linkSocial Media is taking part in different types of online networking, so they are integral in the lives of adolescents. Practitioners need to be able to assess risk, The onset of mental health problems peaks between adolescence and youth and social media are potentially a new dimension to consider. Adolescent voices and practitioner perspectives are central to understanding the relationship between social media and mental health of adolescents. they are rapidly shifting into social media use which has impact at both ends, as boon in form of communication and as bane in the form of mental health problems
Diagnostic accuracy of abdominal ultrasound for detection if acute appendicitis taking operative findings as gold standard
Full text linkThis study objective is to assess the diagnostic accuracy of ultrasonography (USG). While evaluating acute abdominal conditions, including acute appendicitis acute cholecystitis, and pneumoperitoneum. In this study, 342 patients were evaluated to present with symptoms suggestive of acute abdominal pathology. Researchers included patient data including demographic information and USG findings were collected from medical records. In addition, diagnostic accuracy parameters, including sensitivity, specificity, positive predictive value (PPV). Moreover, negative predictive value (NPV), and overall diagnostic accuracy of USG, stratifiend and calculated based on age and gender. The average age of the study was 41.23 ± 6.75 years with a gender distribution. Though the (male: 197, female: 145). USG demonstrated high diagnostic accuracy in detecting acute appendicitis (sensitivity 89.60%, specificity 82.50%. the PPV 88.89%, NPV 83.54%, diagnostic accuracy 86.83%). While the acute cholecystitis (sensitivity 94.44%, specificity 87.10%, diagnostic accuracy 91.04%), and pneumoperitoneum (sensitivity 95.35%, specificity 88.89%, PPV 93.18%, NPV 92.31%, diagnostic accuracy 92.86%). The Stratified analyses by age and gender revealed consistent diagnostic performance of USG. The findings of this study found the diagnostic utility of ultrasonography in evaluating acute abdominal conditions. These results underscore the importance of USG as a frontline imaging modality in the management of acute abdominal emergencie