Jurnal Farmasi Fakultas Kedokteran Universitas Mataram
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Pola terapi dan outcome therapy pasien penyakit ginjal kronik di Rumah Sakit Ansari Saleh Banjarmasin tahun 2023
Full text linkChronic kidney disease is a permanent disease that occurs when the body is unable to maintain the balance of fluids and electrolytes, leading to reduced kidney function. This study quantifies the distribution of therapy profiles among patients with chronic kidney disease, taking into account drug classes, names, doses, and methods of administration. The percentages are calculated based on doctors' statements. This descriptive research used total population sampling as a method for data collection. A total of 55 medical records met the research criteria. The therapy profile that was used most frequently, with a proportion of 13.60%, was the vitamin and mineral group. The medicine name Aminefron® accounted for 8.45% of the results. The prescribed dose was 3x2 capsules per day. The oral route represented the highest percentage of usage, at 55.67%. The doctor's declaration indicated that the percentage of patients who improved was 52.73%, while 38.18% remained sick and 9.09% unfortunately died
Review artikel: validasi metode analisis kafein dalam minuman kemasan menggunakan berbagai instrumen
Full text linkCaffeine is a central nervous system stimulant that is commonly found in packaged beverages. While moderate consumption provides cognitive and physical benefits, excessive intake may cause adverse health effects, including anxiety disorders, insomnia, cardiovascular diseases, and renal dysfunction. Consequently, accurate and validated analytical methods are essential for determining caffeine levels in commercial beverages. This review evaluates analytical instruments and techniques for caffeine quantification, drawing on national and international studies published between 2015 and 2025. The methods examined include UV-Visible Spectrophotometry, High-Performance Liquid Chromatography (HPLC), Gas Chromatography–Mass Spectrometry (GC–MS), Ultra-Performance Liquid Chromatography (UPLC), and High-Performance Thin-Layer Chromatography (HPTLC). Validation was assessed using parameters such as limit of detection (LOD), limit of quantification (LOQ), precision, accuracy, and linearity. The findings indicate that all methods meet acceptable validation criteria. Among them, UPLC demonstrated the highest sensitivity, while HPTLC provided advantages in speed and operational efficiency. Therefore, the choice of method for caffeine determination should be guided by analytical objectives, laboratory resources, and required sensitivity
Pencegahan balita stunting melalui edukasi makanan pendamping air susu ibu (MPASI) yang inovatif
Full text linkComplementary feeding (MPASI) is additional food used to meet the growth and development needs of babies under 5 years old after 6 months. Complementary feeding given early to babies before the age of 6 months has the risk of causing stunting. Early provision of complementary feeding to babies under 6 months of age in Tangsil Wetan Village, Bondowoso Regency is 16.5%. Bondowoso Regency is one of the areas in East Java with a high prevalence of stunting in 2024 of around 32%. This community service activity aims to provide education on providing innovative complementary feeding to mothers of toddlers in Tangsil Wetan Village to prevent stunting. This community service activity uses lecture, question and answer, and demonstration methods. Participants who participated in the counseling activities were given a pretest and a posttest to measure their level of knowledge. The pretest and posttest results showed that mothers' knowledge after being given counseling increased significantly (p<0.05). In addition, demonstrating the right MPASI menu texture according to the toddler's age in this community service activity can be a preventive effort against stunting incidents in Tangsil Wetan Village
Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region
No full textCurrently, there is a phenomenon that shows that many herbs consumed by the public contain medicinal chemicals (BKO). This study aims to identify the presence of BKO prednisone in rheumatic herbs and its levels. This study took five types of samples of rheumatic herbs in Magelang area with different brands, namely samples of herbs A, B, C, D and E, which are available in capsule and powder form. Identification of prednisone in rheumatic herbs was carried out using thin layer chromatography (TLC) method with silica gel GF254 as stationary phase and ethyl acetate: chloroform mixture (4:1) as mobile phase. Quantitative analysis was performed using UV-Vis spectrophotometry with a maximum wavelength of 238.5 nm. The rf value of prednisone standard 0.42 was obtained and quantitative analysis showed that the prednisone content in sample B in the first replication was 3.22%, in the second replication was 2.18%, in the third replication was 2.23%
Analisis kualitatif bahan kimia obat dalam jamu pegal linu di wilayah kabupaten Grobogan
Full text linkThe use of traditional medicine in Indonesia, particularly jamu, remains very popular and an important part of the public health culture. According to the 2018 Riskesdas data, around 59.12% of the Indonesian population consumes jamu, and 95.6% of them recognize the health benefits obtained from it. Jamu, which is made from various types of plants, has been used for thousands of years to maintain health and treat various diseases. This study used Thin Layer Chromatography to identify Medicinal Chemicals (BKO) in jamu circulating in Grobogan Regency, Central Java. The purpose of this study was to analyze the content of medicinal chemicals in traditional herbal medicine. Six samples of jamu pegal linu were tested with Silica Gel 60 F254 stationary phase and different mobile phases for each standard. The results showed that all samples of jamu pegal linu tested did not contain the investigated BKOs, indicating product safety from this aspect
Analisis waste pada depo rawat jalan dengan menggunakan lean hospital di Rumah Sakit Islam Siti Hajar Mataram
Full text linkPharmaceutical installations can provide substantial revenue if managed properly and efficiently. Good or bad service can affect patient satisfaction. For this reason, pharmaceutical installations must improve quality in terms of patient satisfaction, one of which is by reducing waste that occurs in the pharmaceutical service process in hospitals. This study aims to analyze what waste occurs in outpatient depot services to improve service efficiency. This research is descriptive qualitative. Data were obtained through document review, direct observation, interviews. Waste identification uses Value Stream Mapping and Fishbone Diagram to determine the root causes of critical waste that occurs. The results showed that the highest percentage of value added was in the ordinary prescription service of 63.41%, the highest percentage of necessity but non-value added was in the prescription service that required drug distribution from the warehouse unit of 70.79%, and the highest non-value added was in the compounded prescription service process of 36.59%. By using lean hospital, it can be identified that many wastes occur including waiting, transportation, and defects. Increasing service efficiency at the Siti Hajar Mataram Islamic Hospital Outpatient depot can be done by minimizing non-value added activities
Promosi kesehatan remaja melalui program pediatric social responsibility (PSR) di Nusa Tenggara Barat
Full text linkAdolescents needs serious attention because they are at risk of experiencing various health problems. The Pediatric Social Responsibility (PSR) initiated by the Indonesian Pediatric Society, is an innovation program to overcome the health problems of Indonesia adolescents through assistance to health workers who work at primary health centers in various subject including adolescent health promotion. One of its activities in West Nusa Tenggara was carried out in a hybrid seminar aimed to increase knowledge of health workers and related stakeholders regarding adolescent health with a school-based approach. A total of 289 participated in this activity, with 149 (51.6%) participants attending offline Program evaluation was carried out by comparing the knowledge of participants before and after the activity (pre-test and post-test) and evaluating the implementation of the activity. There was a significant difference of participants' knowledge before and after the activity (p-value=0.005; p<0.05). This program was useful (82.2%), held in a sufficient time duration (90.1%), the material was updated (72.9%) and in accordance with the needs of the participants (89.1%), also might be applied in daily work/practice. Similar activities in this PSR program need to be held again regularly with a wider coverage, varied themes and involve teenagers directly
Formulasi gel ekstrak daun sirih cina (Peperomia pellucida L. Kunth) variasi carbopol 940 serta uji fisik dan stabilitasnya
Full text linkChinese betel leaf (Peperomia pellucida L. Kunth) contains tannins, alkaloids, saponins and flavonoids which can inhibit the growth of Propionibacterium acnes bacteria. Gel preparations are suitable for topical therapy of acne. The gelling agent used was carbopol 940. The purpose of this study was to determine the effect and concentration of carbopol 940 which produced the best physical properties of Chinese betel leaf extract gel preparations. This research is an experimental research. Gel preparations were made with various concentrations of carbopol 940 0.5%, 1.0%, 1.5%, and 2.0% then organoleptic examination, homogeneity, pH, adhesion, spreadability, viscosity, skin irritation, physical stability , and hedonic. The data obtained were analyzed with SPSS (trial) using the One Way ANOVA method. The results showed that variations in carbopol 940 concentrations had an effect on organoleptic, adhesiveness, pH, spreadability, viscosity, and hedonics but had no effect on homogeneity, physical stability, and skin irritation. Carbopol 940 concentration of 1.0% produced the best preparation compared to concentrations of 0.5%, 1.5% and 2.0% in terms of physical properties and statistical analysis
Antipyretic activity test of cucumber (Cucumis sativus L.) ethanol and methanol extract on male white mice (Mus musculus)
Full text linkCucumber plants are annual plants that grow in the lowlands or highlands. Cucumbers are easy to get and have lots of benefits, but the peel of the cucumber is still less desirable, so it becomes waste. On the peel of cucumber (Cucumis sativus Linn) showed the active compounds of saponins, phenolics, steroids, protein, calcium and flavonoids. Compounds that have an antipyretic effect are flavonoid compounds. The aim of the research was to determine the ability of the methanol and ethanol extracts of cucumber peels as antipyretics. This study was included in an experimental study by looking at the effect of methanol and ethanol extract cucumber peels on male mice. The method used is chemical induction method. Forty male mice with body weight between 20-30 grams, divided into 8 groupsnegative control, positive control, cucumber peel methanol and ethanol extract dose of 100 mg/kg BW, 200 mg/kg BW, 400 mg/kg BW. The decrease in temperature was observed for 180 minutes with an interval of 30 minutes. It is known that at 30 minutes it has shown a decrease in temperature, until at 240 minutes the temperature drop has reached normal temperature. The data obtained were analysed statistically with One-way ANOVA. The results showed that cucumber peel extract (Cucumis sativus Linn) could provide antipyretic activity at doses of 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW in peptone-induced male mice (Mus musculus), by injecting subcutaneously in the nape of the mice. Â The effective dose Cucumber peel of Ethanol and Methanol extract (Cucumis sativus L.) used to reduce the rectal temperature of male white mice is at a dose of 400 mg/Kg B
Aktivitas antelmintik ekstrak herba meniran (Phyllanthus niruri) terhadap Paramphistomum spp.
Full text linkPhyllanthus niruri is traditionally used to treat intestinal worms. The content of flavonoids in Phyllanthus niruri has the potential as an anthelmintic. The aims of study are to identify flavonoid compounds of the ethanolic extract of Phyllanthus niruri and determine the anthelmintic activity against Paramphistomum spp. Paramphistomum spp. grouped into positive control (Albendazole 10% w/v), negative control (CMC-Na 0.5% w/v), ethanolic extract of Phyllanthus niruri 1.25%, 2.5%, and 5% w/v. For 5 hours, the time and quantity of dead worms were counted every 15 minutes. The average time of death and percentage of worm mortality were then calculate. Differences in average time of death were analyzed with Kruskal-Wallis and Mann Whitney. The results of the test tube and TLC showed the content of flavonoid compounds. Percentage of mortality of Paramphistomum spp. obtained by 100%. Average death time of Paramphistomum spp. at 50, 275, 155, 140, and 115 minutes respectively. Ethanolic extract of Phyllanthus niruri contained flavonoid compounds and has anthelmintic activity with an optimum concentration of 5% w/v although lower than Albendazole 10% w/v (p<0.05)