Jurnal Farmasi Fakultas Kedokteran Universitas Mataram
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Upaya pemberantasan kutu rambut santri, pelatihan produksi sampo antiketombe dan wirausaha barbershop pesantren
Get PDFHead lice, dandruff and other scalp diseases are still one of the main problems of the students at the Nurul Qarnain boarding school. Factors that influence the development of disease are poor personal hygiene due to the students' lack of understanding of this disease. Anti-dandruff shampoo, is expensive and is insufficient to treat head lice problem among students. Furthermore, the absence of professional barbers in the boarding school environment is also one of the factors that triggered this problem. The results of this activity are increased knowledge of students about hair health from 58.8% to 98.24% and the ability and skills of students to make anti-dandruff shampoo and hair cutting. This is expected to increase awareness and ability to care for hair and provide added value to the economy
Analisis perencanaan dan pengadaan guna menjamin ketersediaan obat di rumah sakit
Get PDFManagement of drug is one of the factors which contribute to the quality of hospital services. This study aimed at finding out drug planning in Pharmacy Unit of Adelia Surgical Hospital by using ABC analysis method. This research is qualitative descriptive study involving informants. Primary data were collected by interview with respondents and secondary data report of general drugs purchased period of May 2018 – May 2019. The Result using ABC analysis indicate that there are 23 (17,42%) kindof drugs in group A, 35 (26,52%) in group B and 74 (56,06%) in grup C. Group A if in the event of an excess or deficiency will couse harm to the hospital. ABC analysis method will effectively improve hospital drug consumption plan
Profil penggunaan obat antidiabetes pada pasien diabetes mellitus tipe 2 di instalasi rawat jalan RSUD Provinsi NTB tahun 2018
Get PDFDiabetes mellitus (DM) is a disorder of insulin secretion, insulin action or both, which are characterized by blood glucose levels > 200 mg/dl and / or fasting blood glucose levels > 126 mg/dl. In 2017 Indonesia was recorded as the sixth largest country with DM in the world. The most common classification of diabetes is type 2 DM with an incidence 90-95%. The study aimed to determine the profile of antidiabetic use in type 2 DM patients at the outpatient installation of RSUD Provinsi NTB in 2018. This study used cross sectional design retrospectively with purposive sampling method for the period January-December 2018. The results showed that in 112 patients, 195 antidiabetic agents were prescribed. The antidiabetic prescribed were metformin (33.85%), glimepirid (25.13%), aspart insulin (13.33%), insulin detemir (8.21%), pioglitazone (6.67%), insulin glargine (6.67%), glyclazide (1.54%), gliquidone (1.54%), acarbose (1.54), regular insulin (1.03%), and insulin lispro (0.51%). Overall, antidiabetic use was in accordance with the guideline recommendations. Further research is needed regarding the review of prescriptions and detailed indications in order to increase rationality of drug use, reduce morbidity and mortality and reduce medical costs
Pola peresepan antibiotik pada pasien infeksi saluran kemih di instalasi rawat jalan RSUD Provinsi NTB tahun 2017
Get PDFUrinary tract infection (UTI) is an infection due to the proliferation of microorganisms in the urinary tract. UTI is usually occur in the community at various ages. In 2014, Indonesian Ministry of Health showed that the number of people with UTIs reached 90-100 cases per 100,000 population per year. Antibiotics are the main therapy used in treating urinary tract infections. The purpose of this study was to determine the pattern of antibiotic prescribing in UTI patients and determine the suitability of therapy with guidelines for UTI at the Installation of NTB Provincial Hospital in 2017. The design of this study was descriptive by collecting data retrospectively. The study was conducted on 105 UTI patients at the Installation Hospital of NTB Province in 2017, then the data obtained from the medical record and prescription sections were processed using Microsoft Excel software. The results showed that therapy for UTI patients was antibiotics with the most use of ciprofloxacin (45.71%), then cefixime (40%), urinter (pipemidic acid) (11.43%), levofloxacin (1.90%), cefadroxil (0.95 %). Based on these results, the suitability of prescription was seen from the type of drug and the dosage in the main therapy (antibiotics) was 100% according to the treatment guidelines, but the frequency and duration of administration only reached 99.05% and 88.6%
Formulasi dan evaluasi karakter fisik sediaan gel ekstrak etanol daun salam (Syzygium polyanthum)
Get PDFAbstrak: Bay leaves (Syzygium polyanthum) are known to have antioxidant effects that can neutralize free radicals found in the skin. The objectives of this research are to formulate the ethanol extract of bay leaves into gel formulation and evaluate the physical properties of gel formulation. Ethanol extract of bay leaves was obtained through the maceration method with 70 % ethanol as a solvent. The thick ethanol extract of bay leaves was formulated into gel formulation with CMC – Na as a gelling agent, glycerin as a humectant, methyl paraben as a preservative, and aquadest as a solvent. After the freeze-thaw test was done, there was no change found in organoleptic but there were changes in pH, spreadability, and adhesion. The pH of gel preparation before being in storage was 5 and after being in storage was 6. In the spreadability, gel formulation spread 5,5 cm before being in the storage, and 5,1 cm after being in the storage. Gel adhesion has a sticky time of 8.35 seconds before in being storage and 8.45 seconds after being in storage
Optimasi formula sampo ekstrak daun pacar air (Impatiens balsamina L.) dengan kombinasi natrium lauril sulfat dan cocamide DEA
Get PDFDandruff is an anomalous condition characterized by excessive exfoliation of the horny layer from the scalp. The leaves of the water henna plant (Impatiens balsamina L.) are one of the natural ingredients that have anti-dandruff properties, so they can be used as an active ingredient in making dandruff shampoo. The water henna leaves were extracted using the maceration method with ethanol 96%. Apart from the active ingredients, shampoo also has an important component, namely surfactants. The surfactant used in this study was a combination of sodium lauryl sulfate and cocamide DEA. The purpose of this study was to optimize the surfactant formula of sodium lauryl sulfate and cocamide DEA in water henna leaf extract shampoo. This research was a laboratory experimental research. Formula optimization was done through the Simplex Latice Design (SLD) method approach by making eight formulas. All formulas were evaluated for their physical properties including the foam height test and pH test. The data obtained were processed with Design Expert® software. Based on the physical evaluation of the water henna leaf extract shampoo, the results of the high foam test were 10,025 cm and a pH of 6,12. The results of the acceptability test of shampoo preparations including the parameters of color, smell, texture and viscosity received a fairly good response with the acquisition of values 3,1, 3,3, 3,9 and 4 with information 1 (very dislike), 2 (dislike), 3 (quite like), 4 (like) and 5 (really like). The optimum formula for the shampoo consisting of 5% water henna leaf extract, 1,1863% sodium lauryl sulfate, 19,814% cocamide DEA, 3% CMC, 0,5% citric acid, 0,5% methyl paraben, 0,15% menthol and distilled water had physical properties that meet the requirements of a good shampoo preparation
Aktivitas antioksidan ekstrak etanol daun pecut kuda (Stachytarpheta jamaicensis (L.) Vahl) menggunakan metode ekstraksi berbasis gelombang ultrasonic
Get PDF Free radical is an atom or molecule that has unpaired electrons, is reactive and unstable which can cause damage to cells and tissues. Secondary metabolite compounds in plants such as phenolics, flavonoids, tannins, and saponins can inhibit free radicals. One of the plants that has the potential as an antioxidant is a Stachytarpheta jamaicensis (L.) Vahl. The part of the plant that is often used as a medicinal ingredient by Indonesian people is the leaf part. The leaves of snakeweed are natural ingredients that are rich in phenolic compounds, flavonoids, tannins, and saponins. This study aims to determine the activity of free radical inhibition in the snakeweed leaf extract with Ultrasound Assisted Extraction method. Determination of free radical inhibition activity was examined using DPPH method at the concentration series of snakeweed leaf extracts of 60, 65, 70, 75, 80, and 85 ppm. The comparison solution used was vitamin C made with a concentration series of 4, 5, 6, 7, 9, and 11 ppm. The results showed that vitamin C had a free radical inhibitory activity with an IC50 value of 9.40 ± 0.07 ppm, while the extract of snakeweed leaf had free radical inhibition activity with an IC50 value of 74.32 ± 0.71 ppm. Based on the IC50 value, the intensity of free radical inhibition activity in vitamin C is classified as very strong and the extract of snakeweed leaf is stron
In silico analysis of Trisindoline 1 compound against Mpro SARS-CoV-2 as novel potential drugs candidate
Get PDFThe novel coronavirus 2019 (SARS-CoV-2) is one of the viruses that can infect humans and cause high mortality worldwide. The protease (Mpro) is key SARS-CoV-2 an enzyme mediates the viral replication and the transcription. Mpro is currently used as the candidate for the SARS-CoV-2 vaccine because Mpro is one of the key enzymes in the viral life cycle that essential for interactions between the virus and host cell receptor during viral entry. The Mpro can be a target protein to design the novel drug of SARS-CoV-2. The drug design from natural products that are considered to have low toxicity is needed against the virus. The study aims to determines the potential pharmacology of Trisindoline 1 compound from the sponge Hyrtios altum against SARS-CoV-2 and to find the amino acid residues between interaction ligand-protein receptors. The methods of this study use the virtual screening of Auto Dock Vina and visualization the amino acid residue using Bio via Discovery Studio. The result of this study was the selected marine compound from Trisindoline 1 may have potential to developed as inhibitor of SARS-CoV-2.Keywords: In Silico, Mpro, Sars Cov 2, Trisindoline 1, Sponge
Formulasi sabun mandi cair dari daging putih buah semangka (Citrullus lanatus)
Get PDFWhite flesh watermelon (Citrullus lanatus) is known to contain alkaloids, flavonoids, tannins and polyphenols. Research conducted by Rimando proves that watermelon rind contains the amino acid citrulline reaching 60% which is important in increasing levels of nitric oxide which is a regulator of blood flow, muscle energy metabolism, and mitochondrial respiration during exercise. This study aims to formulate bath soap from watermelon waste that meets the requirements with variations in the concentration of watermelon flesh extract (3%; 6%; 9%). Watermelon flesh extract was extracted by maceration process using 70% ethanol. Evaluations were carried out in the form of organoleptic, pH, free of alkali, high foam and density. The results showed that the three formulas were formulas that met the requirements according to SNI standards based on pH test, free alkali, foam height, and density. Â
Edukasi dan sosialisasi gerakan masyarakat cerdas menggunakan obat (Gema Cermat) dengan metode CBIA
Get PDFA community service about the education of Gema Cermat has been conducted in Lebah Sempaga village, West Lombok, NTB. The objective of these activities was to increase people’s knowledge and skills regarding the use of medicines in a right and rational way. The community service was held in three main steps of Community Based Interactive Method, namely presentation of the materials of Gema Cermat by pharmacist leader in NTB, assessments of people’s knowledge before and after socialization by using questionnaires, and evaluation of the participant skills in medicine identifications through the presentation of the participant representations. 23 people are participating in these activities, dominated by females with the age of about 29-50 years old. However, only 13 of them were finishing the questionnaires. Overall, the result of assessments, as well as the evaluation, showed that there was a noticeable improvement in the understanding of people about Gema Cermat, the precise and rational ways in using medicines, with the percentage of 16% increase. Hopefully, people in that area could spread the information to others so that the side effects due to the non-appropriate use of medicines will reduc