Jurnal Farmasi Fakultas Kedokteran Universitas Mataram
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    Molecular docking study of natural compounds from red betel (Piper crocatum Ruiz & Pav) as inhibitor of secreted aspartic proteinase 5 (Sap 5) in Candida albicans

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    Candida albicans can cause adverse infections in humans. The targeting of Sap 5 is due to its virulence factor in C. albicans. The method used is molecular docking using YASARA structure and BIOVIA Discovery Studio. The purpose of this study was to investigate the molecular interaction between red betel and Sap 5 as a potential inhibitor of C. albicans in infecting humans. The results showed that CHEMBL216163 (9,644 kcal/mol) and MLS000557666 (9,525 kcal/mol) have Binding energy above Pepstatin (9,484 kcal/mol) and affect the active site of Sap 5 so that the two test ligands could be further analyzed

    Cyclea barbata L. Miers.: Penggunaan tradisional, fitokimia, dan aktivitas farmakologi

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    Indonesian people still favor the use of traditional medicine because they believe its side effects are lower than synthetic drugs. One of the plants that can be used in traditional medicine is Cyclea barbata L. Miers, or green grass jelly. This study aimed to explain and summarize the traditional use, phytochemical content, and pharmacological activity of C. barbata. All information on C. barbata was collected from various electronic databases (Google Scholar, Science Direct, and PubMed) using important and related keywords. Secondary metabolites found in stems, roots, and leaves are alkaloids and flavonoids. The pharmacological activities of C. barbata include antibacterial, antioxidant, anti-plasmodial, immunomodulator, Alzheimer, anti-inflammatory, anti-cholesterol, and antiulcer. Although C. barbata has been used empirically, further research is still needed to ensure the effectiveness and safety of this plant

    Analisis tingkat pengetahuan penggunaan antibiotik di masyarakat Desa Lebah Sempage Kabupaten Lombok Barat

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    Antibiotics are drugs used to treat infections caused by bacteria. The results of RISKESDAS in 2013 showed that there were 27.8% of the public storing antibiotics without a doctor's prescription, which could lead to bacterial resistance. One of the factors that influence the use of antibiotics in community is the level of knowledge. The purpose of this study was to determine the level of public knowledge regarding the use of antibiotics using the CBIA (Active Human Learning Way) method. This research is descriptive using the CBIA method. Respondents were given a pre-test questionnaire followed by the delivery of material related to antibiotics, then continued with the post-test. The results showed that there was an increase in public knowledge regarding the use of antibiotics by 16.25% using the CBIA method

    Edukasi herbal dan pengolahan minuman herbal sebagai peningkat sistem imun untuk mencegah infeksi COVID-19

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    The COVID-19 situation at the global and national levels is still at very high risk. A good immune system is needed to protect us from COVID-19. Eating healthy meals and increasing antioxidant consumption can help us to boost the body's immune system. Some herbs in Indonesia that are useful in boosting the immune system based on the Traditional Medicine Formulary are included red ginger, lime, cinnamon, and garlic. The Red ginger rhizome contains gingerol and shogaol, cinnamon bark contains cinnamaldehyde, lime has a high vitamin C content, and garlic bulbs contain ajoene. All of these compounds can synergistically improve the immune system. These ingredients are widely available and are processed into antioxidant herbal drinks that increase the immune system. The activity was carried out using the lecture method, discussion, and pretest-posttest to measure the level of participant knowledge. After the implementation of the activity, public knowledge increased regarding herbal ingredients, their processing, and preparation. As many as 100 percent of respondents were recognized the types of immune system enhancing herbs, 72 percent were understood how to process herbs, and 92 percent were understood how to prepare these herbs

    Optimalisasi pemberdayaan kesehatan dalam implementasi dermatitis di Desa Sungai Alat, Kecamatan Astambul, Kabupaten Banjar

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    Implementation community service in Astambul District, Sungai Alat Village, Dermatitis disease the 6th highest. Unclean environmental conditions, prone to flooding have resulted in Residents of Sungai Alat village being susceptible dermatitis. Objective to implement dermatitis screening Villagers Sungai Alat, Local health workers follow up and explain to cadres how dermatitis screening. Etiology of Dermatitis is not known with certainty, there is an interaction Intrinsic and Extrinsic Factors Dermatitis. Symptoms include itching and skin disorders according specific morphology and distribution. So far there no follow up. Short interviews with 10 villagers, 8 people said that they often experience itching, redness in the hands, feet, ranging from children, adults, the elderly. Itching on skin experienced, because they not realize causes, whether was due allergy to something or fungus. Based on the data above, proposing team wants to improve health status of the community and achieve a better standard of living. Strategy improve quality of health services, one of conducting initial dermatitis screening residents Sungai Alat village, Service Team cadres in the village to screen dermatitis, making easier Residents to get health services. Method implementation use the existing dermatitis hand tool. Assessment is carried out by looking condition of residents' skin and matching with a hand tool, if appropriate, then validate/confirm by asking that have been determined. Activity involved all villagers of Sungai Alat, students and proposing team. Results Activities that will be provided form screening data and data for cadres who can carry out screening stages properly

    Penyuluhan perilaku hidup bersih sehat dalam mewujudkan masyarakat Desa Sembalun timba gading peduli sehat

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    The Clean and Healthy Life Behaviour Program (PHBS) is a  community program designed  to improve the health standard of the community starting from the closest aspect, namely in the family or household. The Clean and Healthy Life Behaviour Program (PHBS) household aspect has 10 main indicators that must be implemented. The East Lombok Regency has a percentage of 47.88% in implementing PHBS, in other words PHBS in the area is still low. Because of the low implementation rate, it is necessary to carry out counselling on PHBS with the aim of knowing  the community of Sembalun Timba Gading Village’s understanding regarding PHBS. The method used in this study is observation related to sanitation problems in Sembalun Timba Gading Village, distributing questionnaires, and conducting counseling. Based on the results of filling out the questionnaire, it was found that the implementation rate of child delivery that is assisted by health workers is (100%); using clean water (100%); healthy latrines (100%), exclusive breastfeeding (85%); weighing the baby every month (80%); washing hands with soap (80%); eradicating mosquito larvae (85%); consuming fruit and vegetables (40%); not smoking (45%); and doing physical activity everyday is 65%. The conclusion of this counseling is that the implementation of PHBS in Sembalun Timba Gading Village is quite good, although the PHBS indicators have not been fully implemented by the local community

    Sosialisasi penanaman dan pemanfaatan tanaman obat keluarga (TOGA)

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    Indonesian people have used herbal plants for generations to overcome health problems, but some people are still lacking in obtaining health services. Tenggareng hamlet, North Jenggik Village, Montong Gading Dstrict, East Lombok Regency, West Nusa Tenggara Province is one of the hamlets that has not optimized the yard as land for growing herbal plants. The yard house is suitable land for planting various types of plants. The purpose of this activities was to increase the knowledge of the community, especially about the cultivation and use of medicinal plants. The method used in this community services were lecturing and discussion method. Involving 42 participants. The results of community services are increasing people knowledge and skills related to the planting and utilization of herbal plants. This can be seen from the occurrence of interactive discussions. In conclusion, by conducting socialization and utilization of Family Medicinal Plants can increase public understanding to optimize Family Medicinal Plants

    Peranan program acara stasiun TVRI NTB sebagai salah satu media edukasi kesehatan pendengaran

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    Television is one of the modern mass media that has the potential to convey information to the public and can also shape and build a person's character and behavior. Not only national media, but local media also play an important role in health education activities. In commemoration of World Hearing Day, Unram Hospital cooperates with local station TVRI NTB to hold a health program through the “Sehat Bugar†program providing education about ear and hearing health as a promotive and preventive effort. The purpose of holding this activity is to raise high awareness among individuals, especially the young millennial generation, regarding their daily attitudes in order to maintain healthy ears and hearing. The activities of the millennial generation who like to listen to music with earphones at a loud volume and for a long period of time can be at risk of hearing loss. The presence of hearing loss is often not realized because they are used to ignoring ear health. Hearing loss can cause barriers to communication and have an impact on a person's quality of life. Therefore, cleanliness and ear health  are  important things that must always be considered and maintained. As an evaluation, this health education activity can be accepted by the community. In practice, the live streaming of this television program has been watched 624 times. In addition, this can also be used as an evaluation to carry out health education activities better in the future

    Sosialisasi gerakan masyarakat cerdas menggunakan obat (Gema Cermat) pada masyarakat di Desa Gunungsari

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    Swamedikasi atau self-medication adalah penggunaan obat-obatan tanpa resep oleh seseorang atas inisiatifnya sendiri. Swamedikasi biasanya digunakan untuk mengatasi keluhan-keluhan penyakit ringan yang banyak dialami masayarakat, seperti demam, nyeri, pusing, batuk, influenza, sakit maag, diare, penyakit kulit. Swamedikasi dilakukan masyarakat untuk meningkatkan keterjangkauan pengobatan. Pengobatan yang tidak rasional kerap terjadi pada swamedikasi. Hasil survei pendahuluan pada masyarakat dusun Balekuwu tentang penggunaan obat, masyarakat pada umumnya mengatasi penyakitnya dengan mengobati sendiri karena pengaruh iklan atau meniru teman, keluarga atau tetangga. Pemerintah melalui Kementerian Kesehatan telah mencanangkan Gerakan Masyarakat Cerdas Menggunakan Obat (Gema Cermat). Kegiatan pengabdian Gema Cermat dilakukan kepada masyarakat Dusun Balekuwu, Desa Gunungsari, Kecamatan Gunungsari, Lombok Barat. Kegiatan ini dilakukan dengan metode sosialisasi secara tatap muka (face-to-face) kepada masyarakat di Dusun Balekuwu. Melalui kegiatan sosialisasi ini, masyarakat dusun Balekuwu mendapatkan informasi tentang cara menggunakan obat dengan baik

    Penyuluhan DAGUSIBU sebagai upaya peningkatan pengetahuan masyarakat Desa Sukadana Lombok Tengah terkait penggunaan dan pengelolaan obat yang rasional menggunakan metode CBIA

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    The lack of health facilities and personnel compared to the population in Sukadana Village makes public knowledge about drug information and self-medication is still very low. Drug information including how to get, use, store and dispose of drugs properly is known as DAGUSIBU. This DAGUSIBU counseling aims to increase the knowledge of the Sukadana village community regarding the rational use and management of drugs. This counseling had been carried out through the delivery of material by pharmacists and continued with practice using the Community Based Interactive Approach Method (CBIA). After the DAGUSIBU counseling was carried out, the community's knowledge about drugs and self-medication had increased compared to the knowledge before the counseling

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