Jurnal Farmasi Fakultas Kedokteran Universitas Mataram
Not a member yet
184 research outputs found
Sort by
Penyuluhan perilaku hidup bersih dan sehat (oral hygiene) di Sekolah Pendidikan Anak Usia Dini Ayah Bunda Sayang, Lombok Barat
The mouth and teeth are one of the entry points for microorganisms such as fungi, bacteria and so on which can cause health problems. Oral and dental health can be achieved by implementing clean and healthy living behaviors (PHBS) oral hygiene such as brushing your teeth properly and being able to keep your toothbrush clean. This community service activity aims to increase the knowledge of young children regarding the practice of maintaining oral and dental health. The method of activity that the author uses is in the form of counseling and mentoring with lecture methods, discussions, and demonstrations on how to brush your teeth properly and correctly. This activity was attended by 16 participants. The player is accompanied by the teacher to fill out the questionnaire. The results of the questionnaire showed that almost of the PKM participants had not properly implemented the behavior of maintaining oral and dental hygiene. Participants took part in this counseling enthusiastically and the results of the evaluation revealed that all participants understood oral hygiene behavior, namely knowing the practice of brushing their teeth and how to maintain cleanliness in brushing their teet
GENGGAM JARIMU : Promosi edukasi relaksasi genggam jari sebagai upaya menurunkan intensitas nyeri sendi
One of the independent interventions that is effective in reducing joint pain in gout arthritis is finger grip relaxation, this relaxation is easy to do. The purpose of implementing this community service is that the community and health cadres are able to recognize gout arthritis and finger grip relaxation, and health cadres are able to understand the measurement of pain scales using the Numerical Rating Scale (NRS). The service was carried out in the village of Tunggul Irang for 3 (three) months, namely measuring pretest and posttest knowledge, measuring uric acid levels, promoting education about gout arthritis and relaxation of finger grips through media stickers and demonstration methods, teaching pain scale measurements to health cadres, then the monitoring stage evaluation for 1 week. The knowledge of the villagers and health cadres about gout arthritis and finger grip relaxation was in the very good category and the majority of uric acid levels were in the normal category and the health cadres had a good understanding of measuring pain scales. Promotion of education optimized both in a structured and gradual manner can increase knowledge and the right choice of complementary therapy to prevent the risk of gout arthritis
Teh herbal terstandar simplisia bunga gemitir (Tagetes erecta Linn.) sebagai kandidat antioksidan baru
Empirically, gemitir flower (Tagetes erecta Linn.) has been used for generations as an alternative to treat whooping cough and eye pain medication. Gemitir flower is potential as an antioxidant because it contains secondary metabolites of phenolic groups, flavonoids, and alkaloids that have been shown to have antioxidant activity. As a pharmaceutical products, medicinal plants must be guaranteed quality and safety. This study aims to determine the suitability of the simplicia quality of gemitir flowers by standardization based on Indonesian Herbal Pharmacopoeia and Indonesian Materia Medica, and also to determine the antioxidant potential of standardized herbal teas of gemitir flowers. This first step of this research were standardization of gemitir flower simplicia based on specific and non-specific parameters, followed by making standardized herbal tea of gemitir flower. Antioxidant activity test was carried out on tea preparations using the DPPH method. The results showed that the simplicia of gemitir flower met all the standard parameters of specific and non-specific standardization with an ash content value of 3,47%, acid insoluble ash content of 0,11%, water soluble extract content of 24,86%, ethanol soluble extract content of 21,67%, drying shrinkage content of 9,33%, moisture content of 9,23% and foreign organic matter of 0,3%. Standardized herbal tea simplicia gemitir flower was able to inhibit 50% of DPPH free radicals at a volume of 33,87 µL. Based on the results, it can be concluded that the empirical use of gemitir flower tea potential as a natural antioxidant
Hilirisasi produk Smart ENT Unit dinilai sangat bermanfaat bagi mitra Fakultas Kedokteran Universitas Mataram
Medical technology continues to grows, both for services and education, thus, innovation is needed. One of these innovations is through the development of the Smart Ear Nose and Throat (ENT) Unit, especially for ear, nose, throat, head and neck surgery (ENT-HNS). In the field of education, this can support problem-based learning (PBL) systems. The development of hardware, software and electronic systems is required in the actualization of this Smart ENT Unit. The method for this community service is by transferring the science and technology that has been produced by the authors to partners. This is to support the use of technology that has been developed by academician to partners, namely the Mataram University Primary Clinic. The result of this community service is in the form of handing over a smart ENT Unit to partners. When the equipment is handed over, assistance is also provided to partners regarding the operation and maintenance of the unit. Eventually, the unit has been used to delivering the health service and education. The conclusion of this community service is that the transfer of the Science and Technology Smart ENT Unit has been successfully completed by the authors. Based on the partner testimonials, the benefits have been felt in regards to this program
Analisis fitokimia dan kromatografi lapis tipis ekstrak etanol daun rosella (Hibiscus sabdariffa L.)
Rosella (Hibiscus sabdariffa L) is a plant belonging to the Malvaceae family. This plant is widely used as herbal medicine. Rosella leaves have many compounds that can function as antioxidants and antibacterials. As a crude material for traditional medicine, it is necessary to know the content of secondary metabolites contained in rosella leaves both quantitatively and qualitatively as one of the standardization parameters. The objective of this study was to determine the content of secondary metabolites contained in the ethanolic extract of rosella leaves through phytochemical analysis and Thin Layer Chromatography. Rosella leaf extraction was carried out by maceration method using 70% ethanol as solvent. Testing the content of secondary metabolites in the ethanolic extract of rosella leaves was carried out by phytochemical screening. Furthermore, the TLC test was carried out to confirm the presence of a positive group of compounds on phytochemical screening. Phytochemical screening from rosella leaves extract revealed the presence of alkaloids, flavonoids, saponins and tannins. The TLC system used in this study was able to separate the phytochemical content and gave positive results confirming the phytochemical screening results. The eluent used was chloroform:methanol:acetic acid with a ratio of 14:2:1 obtained spots with an Rf of 0.737 which is similar to the Rf standard of quercetin which is 0.762
Potensi anti-kanker payudara tanaman songga (Strychnos lucida R.Br): Tinjauan interaksi molekuler terhadap reseptor estrogen-α in silico
Songga (Styrchnos lucida R.Br) is a plant that has potential to be developed as an anti-breast cancer against. This study was conducted to predict the secondary metabolite derived from songga, which potential as anti-breast cancer through inhibition of estrogen receptor-α. A molecular docking study was carried out using Autodock Vina assisted by AutodockTool and Biovia Discovery Studio. The study used estrogen receptor-α as a protein and ten compounds from songga as ligands. The 3D structure of estrogen receptor-α and ten ligands were obtained from Protein Data Bank and the PubChem database. The result revealed that strychnine N-oxide is the compound that has the lowest free binding energy and inhibition constant with the value 9.6 kcal/mol and 0.09 µM, respectively. This indicated that strychnine N-oxide has an excellent affinity for estrogen receptor-α. Thus, this compound is predicted to inhibit the estrogen receptor-α and can be developed as anti-breast cancer. However, further investigations such as molecular dynamics simulation, in vitro and in vivo assays should be undertaken
Uji validitas dan reliabilitas instrumen kuesioner gambaran penggunaan obat nyeri haid secara mandiri pada mahasiswi Fakultas Kedokteran Universitas Mataram
Self-medication often becomes a choice for various complaints, one of which is menstrual pain. Regarding the description of the use of menstrual pain medication independently, it is still limited. The use of a questionnaire as a research instrument that has been tested for validity and reliability is very necessary. Therefore, this study aims to develop and test the validity and reliability of the description of the independent use of menstrual pain medication in female students. This research is a descriptive survey type with a cross-sectional design. The validity test was carried out using a qualitative and quantitative professional assessment method, namely by using the Content Validity Ratio (CVR). An advance validity test was conducted by 5 experts and 40 respondents. The reliability test was carried out with 40 respondents and used the Chronbach Alpha value. The results of the validity test obtained 28 questions with a CVR value of 1. Facial validity was declared valid after one repair. The reliability of the test obtained Cronbach's Alpha coefficient value of 0.934. Based on the validity and reliability test of the questionnaire, it was declared valid and reliable so that all questions could be used as an instrument to find out the description of the use of menstrual pain medication independently
Evaluasi pola penggunaan obat dispepsia berdasarkan indikator WHO (World Health Organization) pada pasien rawat jalan Puskesmas Karang Taliwang tahun 2019
Dyspepsia is a collection of several clinical symptoms consisting of pain in the pit of the stomach, flatulence, early satiety, nausea, and vomiting. The incidence of dyspepsia at the Karang Taliwang Public Health Center until 2019 was quite high. Evaluation of drug use at the Puskesmas has never been carried out, so it is necessary to know the pattern of use of dyspepsia drugs at the Karang Taliwang Public Health Center. This review aimed to determine the pattern of dyspepsia drug use in outpatient dyspepsia at Karang Taliwang Public Health Center using prescribing indicators developed by the World Health Organization. This study is a descriptive study of retrospective drug use. Sampling using a consecutive sampling method. Prescription data and medical records were collected through observation sheets. The results of the study on drug use patterns were the average number of drug items per sheet of 2.55 prescription; the percentage of drugs prescribed with generic names was 99,37%; the percentage of prescription drugs with antibiotics was 1.61%; the percentage of prescription drugs with injection preparations was 0%; and the percentage of drugs prescribed according to the Formularium was 96.84%
Aktivitas antioksidan ekstrak air daun kelor (Moringa oleifera) dengan metode DPPH serta analisis kualitatif kandungan metabolit sekunder
Sunlight contains UV radiation which will have an impact on the skin if exposed continuously and cause premature aging of the skin. The use of cosmetic products that contain antioxidant compounds is needed to avoid premature aging due to exposure to UV rays. Antioxidants used in cosmetics generally come from synthetic compounds, namely BHT (Butyl hydroxytoluene) whose use will have a negative impact on the skin if used in the long term, so in this study, Moringa oleifera leaf was used as a natural antioxidant. The purpose of this study is to determine the antioxidant activity of Moringa leaf water extract by calculating IC50 and using a comparison standard of vitamin C. The method used in this study is the stratified maceration method with measurement of antioxidant activity using the DPPH method. The results showed that the aqueous extract of Moringa leaves contains secondary metabolites of flavonoids, tannins, saponins, and alkaloids that play a role in antioxidant activity. The test results of Moringa leaf water extract showed moderate antioxidant activity with an IC50 value of 87.54 ppm, while the comparison control vitamin C obtained an IC50 of 483.53 ppm. This is because vitamin C has been oxidized so that the ability to donate protons to DPPH free radicals is also reduced
Edukasi mengenai pentingnya PHBS tatanan rumah tangga dalam meningkatkan derajat kesehatan masyarakat di Desa Medana Kecamatan Tanjung Kabupaten Lombok Utara
Clean and healthy living behavior (PHBS) in the household order is to empower household members to know, be willing and able to practice and play an active role in the health movement in the community. PHBS in household order has 10 indicators that must be implemented. Teluk Dalem Hamlet in Medana Village has not yet fully implemented PHBS so that a PHBS extension work program is still being planned. The purpose of the counseling is to increase awareness and empowerment of the community in PHBS in Teluk Dalem Hamlet, Medana Village, Tanjung District, North Lombok Regency. The method used is counseling and evaluation monitoring in Teluk Dalem Hamlet by providing materials, discussions, questions and answers and demonstrations. The results of filling out the PHBS questionnaire were births by health workers (100%); exclusive breastfeeding (80%); weigh the baby every month (70%); use of clean water (85%); wash hands with soap (60%); house free from mosquito larvae (40%); consumption of fruit and vegetables (70%); physical activity (50%); no smoking in the house (25%); and use of healthy latrines (75%). The conclusion in this community service can have an impact on increasing the health status of Teluk Dalem Hamlet, Medana Village, among others, increasing public knowledge about clean and healthy living behavior (PHBS), and being able to practice good handwashing behavior so as to avoid various diseases