Jurnal Farmasi Fakultas Kedokteran Universitas Mataram
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Utilization of dried butterfly pea flower (Clitoria ternatea L.) as a source of natural antioxidants: determination of total flavonoid content and activity test with dpph method
Full text linkButterfly pea flower (Clitoria ternatea L.) is a herbaceous plant known for its high content of bioactive compounds, particularly flavonoids, which serve as natural antioxidants. Commonly used in traditional medicine and functional foods, this flower's ability to neutralize free radicals makes it a valuable natural resource. This study evaluates the antioxidant potential of dried butterfly pea flowers by determining their total flavonoid content and assessing antioxidant activity using the DPPH method. A key novelty of this research lies in the use of controlled oven drying at 50°C, which differs from previous studies employing sunlight drying. This method preserved flavonoids more effectively, resulting in a higher flavonoid content (40.60 mg/100 mg extract) compared to prior reports. Phytochemical screening also detected the presence of saponins and tannins, broadening the understanding of its bioactive profile. Antioxidant activity was evaluated using the DPPH method, yielding an IC50 value of 36.06 ppm, indicating very strong activity. Comparatively, vitamin C as a positive control showed an IC50 value of 2.13 ppm. These findings underscore the advantages of optimized drying and extraction methods, highlighting dried butterfly pea flowers as a promising source of natural antioxidants for applications in functional foods and health products
Strategi pemberdayaan masyarakat dalam penanggulangan stunting: pemahaman, pencegahan, dan intervensi
Full text linkThis community service discusses stunting, a problem of stunted child growth due to chronic malnutrition, especially in the West Nusa Tenggara region of Indonesia. Stunting causes impaired growth in children, with boys growing much less than they should. This condition is often caused by a lack of nutritional knowledge among pregnant women and children, as well as an unbalanced diet. The impact of stunting includes physical and cognitive impairment, increased risk of chronic disease, and lower adult productivity. Stunting prevention requires a holistic approach involving nutrition, health, sanitation and education, as well as active participation from the government, community and family. An intervention program was implemented in Bayan, North Lombok, involving participatory discussions with various community members to improve understanding and prevention of stunting. The PAR method was used in the implementation of the activities, which involved initial mapping, implementation, and evaluation. The results showed an increase in the community's understanding of stunting and its prevention measures. The program highlights the importance of community empowerment in stunting prevention to improve children's quality of life
Edukasi pencegahan hipertensi dan pengetahuan minum obat di lingkungan Pemuda Muhammadiyah Ngaglik
Full text linkHypertension is included in top ten diseases in Sleman Regency 2023 for all age groups. Men have a risk 3 times greater than women. There is a significant relationship between the level of knowledge and adherence to taking medication in hypertensive patients. Therefore, it is necessary to provide services in the form of education regarding the prevention of hypertension and knowledge regarding adherence to taking antihypertensive medication among young people in Sleman. The service was carried out in Sleman Regency with 20 Muhammadiyah youth from Sleman Regency as participants. The service instrument used is a questionnaire. The data was analyzed by classifying the level of education and assessing the percentage of knowledge level of the respondents' answers, which was 50% good, 40% sufficient and 10% less. The results concluded that education had a good impact on the level of knowledge for some respondents
Profil kadar asam urat dan kadar kolestrol pemedek Pura Besakih
Full text linkPura Besakih located in Karangasem district, Bali is one of the largest Hindu worship sites and is considered a center of spirituality. The ceremony of Ida Bhatara Down Kabeh takes place on the tenth month of the Bali Calendar every year. Universitas Bali Internasional (UNBI) has launched a free medical check-up initiative targeting the religious leaders who lead the ceremonies and visitors to the temple who are Hindu during the ceremony. This activity is a real implementation that the UNBI routinely performs every year through Community Services. UNBI collaboration in Pura Besakih not only provides medical check-up but also builds inter-agency relationships and raises the understanding of how vital community health is. This community service activity is carried out through a collaboration between lecturers and undergraduate students of the Bachelor of Medical Laboratory Technology Study Program. This activity has been implemented on April 19, 2023, with a medical check-up covering cholesterol and uric acid levels. This medical examination uses the Point of Care testing method (POCT). This activity concluded that in uric acid tests, there were 40% above normal levels consisting of 34% males (average uric acid levels 8.5 mg/dL) and 66% females (averaged uric Acid levels 6.7 mg/ dL). In the cholesterol tests, 39% were beyond normal levels, which consisted of 26% male (averaging cholesterol levels 230,1 mg/dL) and 74% female (237.2 mg / dL) cholesterol.
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Telaah: self-care mobile application untuk pencegahan luka diabetes
Full text linkSelf-care practices and appropriate glycemic management may prevent diabetic ulcer, a complication that has a detrimental effect on patients and their families. Through mobile-health applications, educational initiatives can increase patient awareness and promote the early preventative measures required to minimize complications from diabetes. The purpose of this review of the literature is to investigate research on the development of mobile-health applications for people with diabetes. The articles reviewed were obtained through keyword searches in the PubMed and Google Scholar databases within the last 10 years. According to seven published articles, six applications were created as self-care resources for people with diabetes mellitus. In order to prevent diabetic ulcer, mobile-health applications might assist people with diabetes maintain their independence in self-care routines
Sugar content evaluation in commercially available lidah kucing pastries: uv-vis spectrophotometric analysis of traditional indonesian confections in pontianak tenggara district
Full text linkGlucose content in confectionery products requires careful monitoring due to its association with serious health conditions including obesity, diabetes, and cardiovascular disease. This study examined glucose levels in three lidah kucing cookie samples from Pontianak Tenggara district retailers to assess nutritional variability in these traditional Indonesian confections. The research employed a dual analytical approach combining qualitative and quantitative methods. Initial screening utilized Fehling and Benedict reagent tests to confirm glucose presence, followed by precise quantitative analysis using the Nelson-Somogyi method with UV-visible spectrophotometry. The quantitative protocol involved standard solution preparation, calibration curve development, optimal wavelength determination, and triplicate sample measurements to ensure analytical reliability. Qualitative testing confirmed glucose presence in all three samples through positive Fehling and Benedict reactions. Quantitative analysis revealed significant concentration variations among products. Sample A contained 0.227 percent glucose, Sample B demonstrated substantially higher levels at 0.993 percent, while Sample C showed minimal glucose content at 0.004 percent. These results indicate considerable variability in glucose concentrations across commercially available lidah kucing products within the study area. The investigation successfully established glucose presence in all examined samples while documenting substantial differences in glucose concentrations among similar commercial products. These findings highlight the importance of analytical monitoring in traditional confectionery items and demonstrate significant nutritional variation among comparable products in local markets. The results provide essential baseline data for consumer awareness and potential regulatory considerations regarding glucose content in traditional Indonesian baked goods, supporting informed dietary choices and public health initiatives
Edukasi deteksi dini kanker payudara sebagai upaya pencegahan penyakit kronis mematikan di Kelurahan Kalisegoro Semarang
Full text linkA major health concern for women is breast cancer, which is the most common cause of death in this population and delayed diagnosis is a major contributor to this. This delay often arises from a lack of public understanding about breast cancer and its potential for harm. However, performing regular breast self-exams (BSE) offers a method for early identification. Therefore, this community service aims to socialize the BSE method to The Family Welfare Program (PKK) mothers in Kalisegoro Urban Village. The method used in this socialization process uses direct counseling. This education seeks to increase knowledge and promote the regular use of the BSE method. This community service is descriptive community service and gathering the data through an evaluation questionnaire administered after the activity's completion. A number of respondents in this community service were residents of Kalisegoro Urban Village. These results show that the service team effectively communicated information about the early detection of breast cancer, and the participants responded positively to it
Review artikel: analisis validasi metode penetapan kadar logam timbal (Pb) dalam kosmetik menggunakan berbagai instrumen
Full text linkLead (Pb) is one of the most commonly found heavy metal contaminants in cosmetic products. Continuous exposure to lead (Pb) can cause pathological changes in body organs and may lead to cancer. Therefore, it is essential to measure the concentration of lead in cosmetics to ensure safety and prevent potential side effects. This article aims to determine the most effective method for analyzing lead (Pb) content in cosmetic preparations using various instruments, including UV-Vis Spectrophotometry and Atomic Absorption Spectrophotometry (AAS). This study was conducted by comparing the validation results of both instruments. The results showed that the lead (Pb) content in most cosmetic preparations was below the safety limit set by the Badan Pengawas Obat dan Makanan (BPOM) Indonesian, which is <20 ppm. Atomic Absorption Spectrophotometry (AAS) was selected as the most optimal method, as it met all validation parameters with high accuracy and precision. It also demonstrated higher sensitivity, with lower LOD (Limit of Detection) and LOQ (Limit of Quantification) values compared to UV-Vis Spectrophotometry. Therefore, AAS is superior in detecting and quantifying lead in cosmetic preparation
Post-harvest process influences antibacterial activity of Clitoria ternatea flower extracts against Staphylococcus aureus and Escherichia coli
Full text linkButterfly pea is a plant with high potential for development as an antimicrobial agent. However, its antimicrobial potential is closely related to its phytochemical profile, which can be influenced by post-harvest processing. This study aimed to evaluate the effect of post-harvest processing on the antibacterial activity of butterfly pea flowers. Butterfly pea flower was prepared using three different methods: fresh, aerobic fermentation, and sun-dried. The samples were extracted by maceration using 96% methanol for 1 day with 3 re-extraction process. Phytochemical screening was conducted using colorimetric method with specific reagents for certain groups. Antimicrobial potential was tested using the well diffusion method on NA media in five different concentrations of extract. Extraction results showed that the three samples produced different extract yields, with sun-dried butterfly pea flower extract giving the highest yield (18%), followed by fresh extract (8%), and aerobic fermentation (0.8%). Phytochemical screening revealed that all three butterfly pea flower samples did not contain quinones and saponins. Additionally, alkaloids were not detected in the fermented extract. Antibacterial activity of the three butterfly pea flower extracts showed significantly different zone of inhibition, with the sun-dried extract consistently providing the largest zone of inhibition compared to fresh and fermented extracts against Escherichia coli and Staphylococcus aureus, with average inhibition zones of 8.67 - 11.17 ± 0.88 mm and 4.25 - 10.5 ± 1.64 mm, respectively. It can be concluded that the post-harvest processing affects the antibacterial activity of butterfly pea flowers
Pengaruh penyuluhan mengenai hipertensi terhadap tingkat pengetahuan masyarakat di Cilolohan, Kota Tasikmalaya
Full text linkHypertension is a medical condition where blood pressure surpasses the normal range, defined by a systolic pressure of 140 mmHg or higher and a diastolic pressure of 90 mmHg or higher. According to WHO data from 2023, the global prevalence of hypertension was 33%, while in Indonesia, it stood at 34.11%. The high prevalence of hypertension raises concerns about more severe complications, such as stroke, heart disease, and kidney failure. This study aimed to provide health education regarding hypertension and its treatment. The methodology began with a pretest questionnaire, followed by educational sessions using the lecture method and leaflet media, and concluded with a posttest questionnaire. The study results indicated that education on hypertension utilizing the lecture method and leaflet media significantly improved the public's level of knowledge (p < 0.05), with an increase of 18.60%. The health promotion and education about hypertension to the society is effective to increase the knowledge level, and may decrease the cardiovascular events in the future