Ufuk Universitesi Akademik Acikerisim Sistemi
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COVID-19 treatment at a glance
Get PDFAs coronavirus disease 2019 (COVID-19) spreads across the world, the ongoing clinical trials are leading to a big race worldwide to develop a treatment that will help control the pandemic. Unfortunately, COVID-19 does not have any known effective treatment with reliable study results yet. In this pandemic, there is not a lot of time to develop a new specific agent because of the rapid spread of the disease. The process of developing a vaccine is long and requires hard work. Although the pathophysiology of the disease is not fully understood, some of the proposed treatment alternatives are based on old evidence and some have been used with the idea that they might work owing to their mechanism of action. The efficacy, reliability, and safety of the currently available treatment alternatives are therefore a matter of debate. Currently, the main therapies used in the treatment of COVID-19 are antiviral drugs and chloroquine/hydroxychloroquine. Other proposed options include tocilizumab, convalescent plasma, and steroids, but the mainstay of the treatment in intensive care units remains supportive therapies
An assessment of career consciousness and career planning awareness of undergraduate students in business administration departments of state and foundation universities
No full textUĞURLU, Pınar. Devlet ve Vakıf Üniversiteleri İşletme Lisans Öğrencilerinin Kariyer Bilinci ve Kariyer Planlama Konusundaki Farkındalıkları Üzerine Bir Değerlendirme, Yayımlanmamış Yüksek Lisans Tezi, Ankara, 2020 Çalışma yaşamı ve teknolojideki gelişmeler ile birlikte, bilgiye sahip olma ve kendini geliştirme olgusu bireyler için stratejik bir önem taşımaktadır. Hayatın her alanında esas alınması gereken sürekli gelişim faaliyetleri, bireylerin her zaman bir adım öne çıkmalarını sağlayacaktır. İşte bu kendini geliştirme, deneyim ve kazanımlarıyla bir mevkii edinme faaliyetlerinin hepsi kariyer olarak adlandırılır. İlgili literatür incelendiğinde bireyler kariyer kararlarını 20'li yaşlarda vermektedir. Bu yaşlar kişinin kendini tanıması, ne istediğine karar vermesi ve o yönde kendine yatırım yapması gereken yıllardır. Bu çalışmanın amacı, İşletme Bölümü öğrencilerinin kariyer bilinci ve kariyer planlamaları konusundaki farkındalıklarını ortaya koymaktır. İşletme Bölümü, mezun olduktan sonra mühendislik, tıp, eczacılık gibi spesifik bir çalışma alanı olmayıp bir çok alanda kariyer sahibi olunabilecek bir bölümdür. Bu yüzden bu öğrenciler için bilinçli bir kariyer seçimi ve kariyer planlama yapmak çok önemlidir. Öğrencilerin bu konudaki yönelimlerini incelemek amacıyla kendilerine "Kariyer Kararı Verme Yetkinliği Ölçeği (KVYÖ)" uygulanmıştır. İlgili ölçek genel ifadeyle kariyer kararı verme öz-yetkinliğini ölçerken, alt ölçekleri ile de "iş/meslek bilgisi, "kendini tanıma", "kariyer tercihi, "kariyer planı oluşturma yolları" ve "mesleki konuları takip etme" hususlarını ölçmektedir. Alınan demografik bilgiler ışığında ise, öğrencilerin kariyer kararları konusunda kendilerini yetkin görmeleri ile yaptıkları arasında fark olup olmadığını ortaya koyarak bu konudaki kararlarının bilinci saptanmaya çalışılmıştır. Çalışma dört bölümden oluşmaktadır. İlk bölümde kariyer kavramı, kapsamı ve önemi, ikinci bölümde kariyer planlama, üçüncü bölümde kariyer kararı ve kariyer kararı verme yetkinliği, dördüncü bölümde ise Ankara'daki devlet ve vakıf üniversitelerinde uygulanan anket çalışması kapsamındaki sonuçlar analiz edilmiş ve değerlendirilmiştir.UĞURLU, Pınar. An Assessment of Career Consciousness and Career Planning Awareness of Undergraduate Students in Business Administration Departments of State and Foundation Universities, Unpublished Master's Thesis, Ankara, 2020 The fact of being knowledgeable and self-improvement in parallel to developments in work life and technology has a strategic significance for individuals. Continuous development activities that need to be taken as the basis in any field of life would ensure individuals to step forward always. Entirety of these activities to acquire a position through self-improvement, experience and gains is called career. Considering the relevant literature, individuals make their career decisions in their 20s. During these ages, the person needs to recognize himself/herself, decide what he/she wants and make investment on that direction. This study aimed to put forward career consciousness and career planning awareness of students in Business Departments. Business Department does not a specific work area after graduation unlike engineering, medicine and pharmacy and it is possible to have a career in multiple areas. Thus, it is critical for students to make a conscious career selection and career planning. "Career Decision-Making Self-Efficacy Scale (CDMS)" was applied to students in order to identify their orientations in this issue. The relevant scale measures the self-efficacy to make a career decision in general sense and its sub scales, on the other hand, measure the matters of "job/profession knowledge", "self-recognition", "career choice", "means of career planning" and "keeping up with occupational topics". In the light of collected demographic data, it was aimed to reveal whether there was a difference between competency perception of students and what they did about their career decisions and to designate whether their decisions on this subject were reached consciously. The study consisted of four sections. The first section analyzed and assessed the career concept, its scope and significance, the second section analyzed and assessed career planning, the third section analyzed and assessed career decision and competency in career decision reaching, and the fourth section analyzed and assessed the outcomes of the scale applied in state and foundation universities in Ankara
Renal transplant alıcılarında transplant sonrası nötrofil-lenfosit oranı ve trombosit-lenfosit oranı ile graft fonksiyonu arasındaki ilişki
Get PDFAim: The aim of this study was to evaluate the association of neutrophil-to-lymphocyte ratio
(NLR) and platelet-to-lymphocyte ratio (PLR) with acute rejection after kidney
transplantation.
Material and Methods: A total of 36 adult renal transplant recipients (33 males, 3 females)
with a median age of 41 (range, 19-64) years were included in this retrospective study
conducted between January 2016 and January 2019. Data on patient demographics and
laboratory findings (neutrophil, lymphocyte, platelet, creatinine, eGFR, serum uric acid and
C-reactive protein) were recorded. Acute rejection was defined via renal biopsy in accordance
with Banff criteria.
Results: Acute rejection occurred in 16 (44.4%) patients. NLR (median 3.75 vs. 1.99, p=0.001)
and PLR (median 125.59 vs. 99.23, p=0.008) values were significantly higher in the acute
rejection group than in the control group. Area under the curve was calculated to be 0.822 for
NLR and to be 0.759 for PLR. Cut-off values were determined to be >2.5 (75% sensitivity and
75% specificity) for NLR and to be >108 (81% sensitivity and 65% specificity) for PLR.
Univariate analysis revealed a strong correlation of acute rejection both with NLR >2.5 (Odds
Ratio (OR)=0.267, 95% Confidence Interval (CI)=0.089-0.803, p=0.019) and PLR >108
(OR=0.231, 95% CI=0.066-0.810, p=0.022).
Conclusion: In kidney transplant patients, there is a strong relationship between high NLR
and PLR values and the development of acute rejection. As simple, easy-to-access, inexpensive
and non-invasive methods, PLR, and particularly NLR, may be potential tests to diagnose posttransplant acute rejectio
Research on the relationship between service quality and Full-Time Production (JIT) in health institutions
No full textTam zamanında üretim (JIT) sistemi işletmelerin en az stokla en karlı ve en kaliteli şekilde hizmet ve ürün sunumunu gerçekleştirmeyi hedefleyen bir sistemdir. Sağlık kurumları açısından Tam zamanlı üretim kaliteden ödün vermeden zamandan tasarruf sağlamayı, israftan doğacak maddi zararı en aza indirmeyi hedefleyen bir sistemdir. Hizmet sektörleri arasında sağlık kurumları kar amacından önce insan hayatına odaklı hizmet sunumu sağlamaları açısından; üretim ve sunum aşamalarında her türlü riski her türlü kaliteyi her türlü memnuniyeti sağlamakla yükümlüdürler. Bu çalışmamda sağlık kurumlarındaki kalite yönetimi anlayışını ve kalitenin kuruma etkileri incelemiştir. Ayrıca kalite yönetimiyle tam zamanlı üretim anlayışına sahip sağlık kuruluşlarının bağı irdelenmiştir. Önemli olan hizmet sunumunun ortaya çıkması değil, hizmet sunumu ortaya çıkarken ki işlemlerin en az maliyetle en kaliteli bir şekilde sunumunun gerçekleşmesidir. Tam Zamanlı Üretim ve Hizmet Kalitesi hakkında çeşitle sağlık hizmetlerinin uygulama sitemleri göz önüne alınarak proje çalışması gerçekleşmiş bulunmaktadır. Sağlık sistemlerinde Tam Zamanlı Üretimin gerçekleşmesi kalite açısından hiçbir aksaklık gerçekleştirmediğine ve stok seviyelerinin en aza indirgenerek üretimin sağlanması / hizmetin sunulması daha da kaliteyi doğru oranda etkilediği tespit edilmiştir.Just in time production (JIT) system is a system that aims to provide the most profitable and highest quality service and product with the least stock. In terms of health institutions, full-time production is a system that aims to save time without sacrificing quality, and to minimize the material damage that may arise from waste. Health institutions among the service sectors in terms of providing service focused on human life before profit; They are obliged to provide all kinds of risks, all kinds of quality, all kinds of satisfaction during the production and presentation stages. In this study, he examined the understanding of quality management in health institutions and the effects of quality on the institution. In addition, the connection between quality management and healthcare institutions that have full-time production understanding was examined. The important thing is not the emergence of service delivery, but the realization of the best quality delivery of the transactions while the service delivery occurs at the least cost. Project work has been carried out regarding Full Time Production and Service Quality, taking into account the application systems of various health services. It has been determined that the realization of Full-Time Production in health systems does not cause any disruptions in terms of quality and that the provision of production / service provision by minimizing the stock levels affects the quality even more correctly
Localized infection and leg ulcer after platelet-rich plasma injection
Get PDFAlthough many studies report effective use of platelet-rich plasma (PRP) injection inthe clinics, almost no study reports any side effects. The patient who was treatedwith PRP injection in gastrocnemius muscle developed complications. The authors ofthis study present a case which may show the possible side effects of PRP
Chest compression methods in simulated Covid-19 patient resuscitation: a randomized cross-over simulation trial
Get PDFBackground: High-quality chest compression is one of the key elements of resuscitation to return of spontaneous
circulation. In the COVID-19 era, medical personnel should wear personal protective equipment (PPE) against
aerosol generating procedures (AGP) during resuscitation. However, the use of this personal protection equipment
may reduce the effectiveness of medical procedures performed.
Objective: We aimed to compare chest compression quality parameters between standard manual chest compression
and chest compression with TrueCPR feedback device performed by medical students wearing full personal protractive
equipment against aerosol generating procedure.
Methods: The study was designed as a randomized, cross-over, single-blinded simulation study. Thirty-two medical
students wearing PPE-AGP performed 2-min continuous chest compression on an adult simulator with and without
TrueCPR feedback device.
Results: Median chest compression depth with and without TrueCPR feedback device varied and amounted to 46
(IQR; 42-53) vs. 41 (IQR; 36-45) mm (MCC vs. TrueCPR, respectively). The manual chest compression rate was 117
(IQR; 112-125) compressions per minute (CPM) and was higher than with TrueCPR feedback device - 107 (IQR; 102-
115; p = 0.017). Full chest relaxation in the manual's chest compression technique (without TrueCPR) was 33 (IQR;
26-42)% and was lower than with chest compression with TrueCPR feedback device - 58 (IQR; 40-75)% (p=0.002).
Conclusions: We conclude that a TrueCPR feedback device improves chest compression quality during simulated
COVID-19 resuscitation performed by medical students wearing PPE-AGP
Elevated serum calprotectin as an inflammatory marker in obstructive sleep apnea
Get PDFOBJECTIVE To investigate the serum calprotectin (SCal) levels and neutrophil/lymphocyte ratio (NLR) values in patients with obstructive sleep apnea (OSA).
METHODS Sixty-seven OSA patients and 46 healthy volunteers without any sleep disorders were included in the study. The patient group was divided into three subgroups according to the severity of OSA. The SCal levels and NLR values were compared among subgroups and between the experimental and control groups.
RESULTS The mean SCal level and NLR value were higher in the study group than in the control group (p = 0.002 and p = 0.001, respectively). The SCal levels were significantly higher in patients with severe OSA than in those with moderate and mild OSA (p = 0.004 and p = 0.001, respectively).
DISCUSSION Unlike NLR, the SCal level may inform the severity of OSA and could be used as an indicator for OSA
Application of vascular endothelial growth factor at different phases of intestinal ischemia/reperfusion: what are its effects on oxidative stress, inflammation and telomerase activity?
Get PDFBackground. Intestinal ischemic reperfusion injury (IRI) represents a great challenge in clinical practice, with high morbidity and mortality. Vascular endothelial growth factor (VEGF), asasignal protein, contributes tovasculogenesis and angiogenesis.Objectives. To evaluate the local effectiveness of VEGF following intestinal IRI and its relation with application time.Material and methods. Thirty Wistar albino rats were allocated to5 groups and underwent laparotomy. Thesuperior mesenteric arteries (SMA) were dissected in4 groups, while thecontrol group (GrC) underwent aresection ofsmall and large intestines. The VEGF group (Gr V) received VEGF following SMA dissection, with no further intervention, and theremaining 3 groups were subjected toischemia for 90min through occlusion ofSMA and reperfusion for 4h. Ischemic reperfusion group (Gr I/R) received no additional medication, while theremaining 2 groups received VEGF just before ischemia (Gr V+I/R) and during reperfusion (Gr I/R+V).Results. Both applications of VEGF caused decreases inplasma levels of interleukin6 (IL-6), tumor necrosis factor ? (TNF-?), intestinal malondialdehyde (MDA), oxidized glutathione, protein carbonyl levels, and increases inintestinal total glutathione and superoxide dismutase (SOD) levels. Telomerase activity, which disappeared for Gr I/R, was found to be elevated following both treatment groups. Similarly, the histopathological scores were found better for both treatment groups, but Gr V-I/R represented best outcomes.Conclusions. The findings of our study revealed that VEGF, applied either before ischemia or during reperfusion, iseffective onlocal damage following intestinal IRI. Byinterpreting thebiochemical analysis and histopathological findings, we conclude either treatment option to be considered according to the reason of intestinal IRI
Neonatal bladder-derived mesenchymal stem cells ameliorate bladder dysfunction in diabetic rat models
Get PDFPurpose: To evaluate the effect of a new mesenchymal stem cell type derived from the neonatal bladder (nMSC-B)
on diabetic bladder dysfunction (DBD).
Materials and Methods: nMSC-B were harvested from neonatal male Sprague-Dawley rat’s bladder and expand- ed in culture. nMSC-B were transferred to Type-1 diabetic rats which were induced by a single dose 45 mg/kg
Streptozocin (STZ). Stem cells were transferred via intraperitoneally (IP) (DM-IP group, n:6) and by direct injec- tion to the detrusor (DM-D group, n:6) at 12th week following diabetes and compared with Phosphate Buffered
Saline (PBS) injected diabetic rats (DM-PBS group, n:6) and age-matched PBS injected non-diabetic normal rats
(NR-PBS group, n:6). All rats were evaluated histopathologically and functionally four weeks after the stem cell
treatment.
Results: nMSC-B showed improvement in both voiding function and bladder structure. The maximum voiding
pressure (MVP) values in the DM-PBS group were lower compare to DM-IP, DM-D and NR-PBS groups (13.27 ±
0.78 vs 16.27 ± 0.61, 28.59 ± 2.09, 21.54 ± 1.00, respectively, P < .001). There was a significant improvement for
MVP values in stem cell-treated groups. Immunohistochemical examination revealed decreased bladder smooth
muscle (SM), increased fibrosis and desquamation in urothelia in diabetic groups compared to normal group(P <
.001). We detected recovery in the stem cell groups. This recovery was more evident in DM-D group. No statisti- cal difference was observed in SM and fibrosis between DM-D and NR-PBS groups (P = .9).
Conclusion: It was shown that nMSCBs provided amelioration of DBD. We think that nMSC-B constitutes an
effective treatment method in DBD
İngilizce öğretim görevlilerinin stresi: Devlet ve vakıf üniversiteleri arasındaki karşılaştırmalı analiz
No full textBu çalışma, Ankara'daki devlet ve vakıf üniversitelerinde çalışan İngilizce okutmanlarının mesleki stres faktörleri ile ilgili karşılaştırmalı bir analiz yapmak ve mesleki stres puanları ile cinsiyet, toplam okutmanlık deneyimi, üniversite türü ve yönetim ya da herhangi bir ek birim görev katılımı gibi demografik değişkenlerle aralarında istatistiksel olarak anlamlı farklar olup olmadığını ortaya koymak için yürütülmüştür. Petek (2008) tarafından oluşturulmuş, 'Alana Özel Stres Faktörleri Anketi' ve 'Örgütsel Stres Faktörleri Anketi'ni içeren "İngilizce Okutmanlarının Stres Sebepleri Anketi" kullanılarak Ankara, Türkiye'deki hem devlet hem de vakıf üniversitelerinin Yabancı Diller Bölümlerinde görev yapan 330 İngilizce okutmanından toplanan veriler bir araya getirilmiştir. Toplanan veriler SPSS 22 kullanılarak analiz edilmiş ve betimsel istatistik testleri ve parametrik yöntemlerden Independent Samples t-Test ve One-way ANOVA testleri kullanılmıştır. Demografik değişkenler göz önünde bulundurulduğunda mesleki stres puanlarında oluşan değişiklikleri saptamak için Independent Samples t-Test uygulanmıştır. Devlet üniversitelerinde görev yapan okutmanların vakıf üniversitelerinde çalışanlara oranla mesleki strese bağlı olan örgütsel strese daha çok sahip oldukları gözlemlenirken, diğer demografik değişkenlerin mesleki strese etkileri ile ilgili istatiksel anlamlı bir fark ölçülmemiştir. ANOVA bulguları, öğretmenlik deneyiminin, alana özel stres puanları üzerinde anlamlı bir etkisi olduğunu ortaya çıkarmaktadır. Bunun üzerine hangi gruplar arasında anlamlı bir etki olduğunu saptamak için LSD testi kullanarak çoklu karşılaştırma yapılmıştır. Betimsel istatistikler sonucunda, "Öğrenci Tutumları" ve "İş Yükü Fazlalığı"nın bu çalışmaya katılım sağlayan İngilizce okutmanları için en yaygın mesleki stres kaynağı olduğu görülmektedir.The present study was conducted to make a contrastive analysis about the occupational stressors of English instructors working at School of Foreign Languages in the public and foundation universities. The aim of this study was also to explore whether there was significant differences between the occupational stress scores and the demographic variables such as gender, years of experience in teaching profession, type of institution, the involvement in any additional duty. By using 'Teacher Stress Questionnaires' including 'Field-specific Stress Questionnaire' and 'Organizational Stress Factors Questionnaire' constructed by Petek (2008), data was gathered from 330 EFL teachers working in the in both public and foundation universities in Ankara, Turkey. The collected data were analyzed using SPSS Version 22, and descriptive analysis, Independent Samples t-Test and One-way ANOVA were conducted. To determine the differences in occupational stressors with respect to the demographic variables, Independent Samples t-Tests was carried out. It was observed that instructors working at public universities turned out to have more organizational stress than the ones working in foundation universities while the other demographics played no significant difference considering the scores of occupational stress. The results of ANOVA revealed that there was a significant effect of teaching experience on field-specific stress scores. Accordingly, the post hoc multiple comparison using LSD test was used to find out the relationship between groups. After analyzing the descriptives, it was also reported that 'Student Attitude' and 'Work Overload' were the most prevalent occupational stress factor of all for the English instructors participated in the current study