Ufuk Universitesi Akademik Acikerisim Sistemi
Not a member yet
2287 research outputs found
Sort by
Problematic whatsApp use among adolescents: linking fear of missing out and psychiatric symptoms
Get PDFObjective: WhatsApp (WA) is the most popular instant message application all over the world. Although communication has become easier and enjoyable with the help of this application, the overuse, and addiction of WA has become an important problem among adolescents. WhatsApp addiction is a part of problematic smartphone use (PSU). When we examined previous studies, we found that the samples were generally composed of young adults, but studies on adolescents who are at high risk for problematic Whatsapp use (PWU) were insufficient, and almost no studies were conducted in the clinical adolescent sample. In this study, we aimed to increase our knowledge about problematic PWU and possible risk factors including fear of missing out (FoMO), PSU, and psychiatric symptoms among adolescents who applied to outpatient psychiatry clinics.Methods: 197 adolescents (136 boys, 61 girls, age: 12-18 years) recruited the study. Problematic Mobile Phone Usage Scale (PMPUS), Bergen Whatsapp Addiction Scale, Brief Symptom Inventory, and Fear of Missing Out (FoMO) Scale were used.Results: We grouped the sample as PWU (Problematic WhatsApp use) and Normal Use group due to Bergen WA Addiction Scale. PWU group’s adolescents were significantly older than others (p=0.03), and had higher scores in all subscales of Brief Symptom Inventory (BSI), FoMO and PMPUS (for all scale scores p<0.001). Regression analysis demonstrated that FoMO is a predictor of PWU. Also, paranoid ideation, psychoticism, phobic anxiety, and somatization had a positive effect (ß=1.80, 0.98, 1.26, 0.52; respectively) while obsession compulsion and depression had a negative effect on PWU (ß=-0.76, – 1.22, respectively).Conclusion: Our results demonstrated that problematic Whatsapp use is an important internet-related behavioral problem and have specific risk factors among adolescents. Adolescents use Whatsapp generally with their real friends/relatives. Adolescents who have depression, obsession-compulsion mostly have social withdrawal, and would not be interested in communicating their real social environment. On the other hand, adolescents who have phobic anxiety, paranoid ideation, psychoticism and somatization symptoms would follow the changes and events more closely. The associations between different psychiatric symptoms and PWU could guide the practitioners in the psychiatric care of adolescents
Cholesterol-related gene variants are associated with diabetes in coronary artery disease patients
Get PDFCoronary artery disease (CAD) which is a complex cardiovascular disease is the leading cause of death worldwide. The changing prevalence of the disease in diferent ethnic groups pointing out the genetic background of CAD. In this study, we aimed to evaluate the contribution of selected cholesterol metabolism-related gene polymorphisms to CAD presence. A total of 493 individuals who underwent coronary angiography were divided into 2 groups: normal coronary arteries (?30% stenosis) and critical disease (?50% stenosis). Individuals were genotyped for APOC1 (rs11568822), APOD (rs1568565), LIPA (rs13500), SORL1 (rs2282649), and LDLR (rs5930) polymorphisms using hydrolysis probes in Real-Time PCR. Blood samples were drawn before coronary angiography and biochemical analyses were done. The results were statistically evalu ated. When the study group was stratifed according to CAD, the minor allele of APOD polymorphism was found related to decreased risk for T2DM in the non-CAD group. In logistic regression analysis adjusted for several confounders, LDLRrs5930 polymorphism was found associated with T2DM presence in the male CAD group [OR=0.502, 95%CI (0.259–0.974), p=0.042]. Besides, APOD and LIPA polymorphisms were shown to afect serum lipid levels in non-CAD T2DM patients (p<0.05). The minor allele of APOC1 was found associated with triglyceride levels in males independent of CAD status. Besides, LDLR minor allele carrier females had elevated HbA1c and glucose levels independent from CAD status in the whole group. The cholesterol metabolism-related gene polymorphisms were found associated with T2DM and biochemical parameters stratifed to sex, CAD, and T2DM status
Is emergency endoscopic retrograde cholangiopancreatography safe in COVID-19 pandemic?
Get PDFCoronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 is now a pandemic worldwide and clinicians have many questions about the safety of interventional procedures, even in an emergency [1]. Here, we will present an endoscopic retrograde cholangiopancreatography (ERCP) case safely performed in emergency situations in a case known to be COVID-19 positive. An 81-year-old male patient was admitted to the emergency department with right upper quadrant pain, jaundice and fever of the last 2 days. In his evaluation, obstructive jaundice due to cholelithiasis and cholangitis was determined. ERCP was performed by duodenoscope (Olympus, TJF-150) with needle-knife sphincterotomy (Microtech) and precut. The procedure was completed without acute complications, after ERCP his bilirubin levels and complaints improved. On the fourth day of ERCP, he had an acute coronary syndrome, coronary angiography was performed and a coronary stent was inserted. Due to stent insertion, 600 mg clopidogrel, 300 mg acetylsalicylic acid, and 6000 IU enoxaparin were given to the patient. On the fifth day of ERCP, he had melena, with a 2 g/dl decrease in hemoglobin levels. Because he was having a 38.5°C of fever and cough, COVID-19 rapid blood test (OVIOSR) determining the serology of Corona virus-19 was performed which was positive. We performed ERCP again, with maximum protection using appropriate equipment (Fig. 1). On the sphincterotomy line, there were blood cloths and they were cleaned with serum physiologic. Coagulation was achieved with the tapered tip sphincterotome (Microtech), choledoch was selectively cannulated, and 10F 10 cm plastic stent (10F, 10 cm; Microtech) was inserted. Two hemoclips (Sureclip, MicroTech) were inserted, and at the end of the procedure, there was no bleeding. After ERCP, because COVID-19 rapid blood test was positive, the real-time PCR test for nucleic acid determination in respiratory samples for COVID-19 was sent to the laboratory which was positive and thorax computerized tomography was performed which revealed bilateral ground-glass opacities in basal parts of the lungs. Instantly, COVID-19 treatment including hydroxychloroquine (2 × 400 mg loading and 2 × 200 mg maintenance) and azitromycine (1 × 500 mg loading and 1 × 250 mg maintenance) started [2]. On follow-ups, his hemoglobin levels did not decrease and his vital signs were stable. After 7 days of treatment for Coronavirus-19 in ICU, his real-time PCR test for nucleic acid determination in respiratory samples (NCOV-19) was negative and he was discharged. Due to the contact history, rapid test results and PCR in healthcare workers in this team were negative, and no COVID symptom was observed during the 14-day follow-up. In conclusion, if adequate precautions are taken, emergency ERCP procedures can be performed safely without any harm to the healthcare workers and patients
Do follicular fluid advanced glycation end products levels affect the ovarian response in unexplained infertility?
Get PDFObjective: To compare the advanced glycation end products (AGEs) levels in follicular fluid according to
the different ovarian responses of women who underwent controlled ovarian stimulation due to unexplained
infertility and to examine the relationship between these levels and pregnancy outcomes.
Methods: Sixty-three women who underwent fresh IVF/ICSI cycles with GNRH antagonist protocol were
divided into 3 groups according to the number of retrieved oocytes as suboptimal (4–9 oocytes), optimal
(10–15 oocytes) and high (>15 oocytes) responders. AGEs levels in follicular fluid were measured by
ELISA method.
Results: AGEs levels were 6.81 ± 2.20 mg/ml, 5.30 ± 2.01 and 6.44 ± 1.43 mg/ml in suboptimal, optimal and
high response group, respectively. AGEs level was significantly higher in suboptimal response group than
in optimal response group. The cutoff level of 6.19 mg/ml had a sensitivity of 59.3% and a specificity of
66.7% in distinguishing the suboptimal response group from the optimal response group. However, there
were no statistically significant difference between AGEs levels and clinical pregnancy and live birth rates.
Conclusion: Increased AGEs level in follicular fluid may be associated with decreased ovarian response
during controlled ovarian stimulation in unexplained infertility case, however, it does not provide information
about pregnancy outcomes
Abnormal foot angles has an association with ingrown toenail
Get PDFBackground: Onychocryptosis, frequently termed ‘‘ingrown toenail’’ is a common
foot problem in routine dermatology and orthopaedic clinical practice which leads to
pain and disability. Although the aetiology of ingrown toenail is not well understood
various associated risk factors have been identified with the pathogenesis.
Material and methods: This study was a retrospective investigation of 170 patients
with hallux valgus and lateral border ingrown toenail of all stages. The patients were
compared with a control group. The radiologic assessment in both groups included
right hallux valgus angle, left hallux valgus angle, right first and second intermetatarsal
angle, and left first and second intermetatarsal angle.
Results: There were 121 female and 49 male patients in the case group and 68 female
and 32 male in the control group. The mean age of the case group was 41.1 years
and 41.1 years in the control group. A statistically significant difference was found
between the case and the control groups in terms of the right hallux valgus angle
variable.
Conclusion: The abnormal hallux valgus angle and the abnormal intermetatarsal angle
plays an important role in ingrown toenail aetiology. The X-rays
of the feet should be
performed to determine the susceptibility of the patients who are admitted to the
hospital for ingrown toenail in order to prevent other toes ingrown toenail and for
planning the treatment of the patients with an ingrown toenail
Mean platelet volume may not be a marker for prognosis in patients with aneurysmal subarachnoid hemorrhage
Get PDFÇÖLYAK HASTALIĞINDA FİBROMİYALJİ SIKLIĞI VE FİBROMİYALJİNİN HASTALAR ÜZERİNE ETKİSİNİN DEĞERLENDİRİLMES
No full textAMAÇ: Çölyak hastalığı, gluten ilişkili bir enteropati olmakla birlikte malabsorbsiyona bağlı bütün vücudu etkileyebilen bir hastalıktır. Diğer yandan antijen maruziyeti sebebiyle kronik inflamasyona da zemin hazırlamaktadır. Kronik inflamasyonun vücutta sistemik etkilerinin olduğu bilinmektedir. Çölyak hastalığının sistemik etkileri farklı mekanizmalar üzerinden fibromiyalji sendromunu (FMS) tetikliyor olabilir. Çalışmamızın amacı Çölyak hastalarında FMS prevalansını belirlemek ve FMS’nin Çölyak hastaları üzerindeki etkisini değerlendirmektir. GEREÇ VE YÖNTEM: Çalışmaya 1 Şubat-10 Haziran 2019 tarihleri arasında Gastroenteroloji kliniğimize başvuran 24 Çölyak hastası (7 aktif, 17 Çölyak diyeti altında) ve 20 kontrol gönüllü olarak dahil edildi. FMS tanısı için 2010 American College of Rheumatology kriterleri kullanıldı. WSPI (yaygın ağrı indeksi), SSS (somatik semptom ağırlık skoru) ve toplamından FMS skoru hesaplandı. Bütün katılımcılara fibromiyalji etki anketi uygulandı. Veriler istatistiksel olarak karşılaştırıldı. BULGULAR: Çölyak hastaları ve kontrol grubunda FMS sıklığı birbirleriyle karşılaştırıldığında anlamlı farklılık saptanmadı; Çölyak hastalarında %12,5, gönüllü kontrol grubunda %5 (p: 0,61). Kadın ve erkeklerdeki FMS sıklığı benzerdi. Gruplar arasında WSPI, SSS ve FMS skorları açısından anlamlı fark yoktu. FMS etki skalası skorları yönünden FMS olanlar ile olmayanlar karşılaştırıldığında gönüllü kontrol grubunda anlamlı fark yoktu (23,9±18,8 ve 21,5±0; p: 0,90). Çölyak hastalığı olanlarda, FMS etki skoru FMS olanlarda olmayanlara göre daha yüksek olmasına rağmen anlamlılık düzeyine ulaşmamıştır (51,9±25,5 ve 28,5±17,7; p: 0,25). SONUÇ: Türk toplumunda Çölyak hastalarında FMS sıklığını gösteren ilk çalışmadır. Normal popülasyona göre Çölyak hastalığında FMS sıklığı artmamaktadır. Çölyak hastalığında aktivitenin FMS üzerine etkisi yoktur. FMS tanısı olan Çölyak hastalarında olmayanlara göre hayat kalitesi daha çok etkilenmektedir. Daha geniş bir popülasyonda yapılacak çalışmalara ihtiyaç vardır
An anatomical study of the bicipital aponeurosis in embalmed and fresh frozen cadavers
No full textObjectives: The bicipital aponeurosis is a fascial expansion which arises from the distal tendon of biceps brachii muscle. It is an important structure for protecting the median nerve and brachial artery. The aim of this study was to analyze the morphometry and shape of the bicipital aponeurosis and its implications for the protection of the median nerve and brachial artery. Methods: Upper extremities of two fresh frozen and seven embalmed cadavers (five right, four left sides) were dissected. The ages of the cadavers varied between 60–86 years. The central length, superior width, central width, inferior width and the shape of bicipital aponeurosis were evaluated. All measurements were performed by using digital caliper. Results: The central length of the bicipital aponeurosis was measured 3.6±1.2 cm. The superior, central and inferior width of the bicipital aponeurosis were found 1.5±0.7 cm, 1.5±0.6 cm and 1.8±0.8 cm, respectively. Through the examination of upper extremities; two different shapes of bicipital aponeurosis were observed. In type I; the bicipital aponeurosis was fusiform in shape and observed in four upper extremities. In five extremities, it was found as quadrangular in shape and classified as type II. Conclusion: The morphometry and shape of bicipital aponeurosis have a clinical importance to protect the median nerve and brachial artery or to reduce compression of these neurovascular structures. A better understanding of bicipital aponeurosis morphometry is important in assessment of biomechanical properties of biceps brachii
Farklı Fenotiplere Sahip Polikistik Over Sendromlu Hastaların Klinik ve Laboratuvar Parametreleri Yönünden Değerlendirilmesi
No full textAmaç: Polikistik over sendromu oligo/anovulasyon, klinik veya biyokimyasal hiperandrojenemi, polikistik overlerle karakterize heterojen bir hastalıktır. Bu çalışmada amacımız farklı fenotiplere sahip polikistik over sendromlu (PCOS) hastaların klinik ve laboratuvar parametreleri yönünden değerlendirilmesini sağlayarak hastalığın uygun tanı ve tedavisine katkı sağlamaktır. Gereç ve Yöntemler: Çalışma Ekim 2013-Mayıs 2015 tarihleri arasında Ufuk Üniversitesi Tıp Fakültesi Dr. Rıdvan Ege Hastanesi ve Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum kliniklerinde ortak olarak yürütülmüştür. Çalışmaya PCOS tanısı konulan 760 (%89.1) hasta ve 93 (%10.1) sağlıklı birey dahil edilmiştir. PKOS’lu hastalar dört ana fenotipe ayrılmış olup, bu fenotipler hem kendi aralarında hem de kontrol grubu ile karşılaştırıldılar. Bulgular: PKOS fenotiplerin ülkemizdeki prevalansı 1. fenotip %45.7, 2. fenotip %10, 3. fenotip %17.8 ve 4. fenotip için %26.6 olarak saptandı. Fenotip 1 klinik ve biyokimyasal olarak en hiperandrojen fenotip olarak tespit edildi. 1. ve 2. fenotiplerde BMI değerleri daha yüksekti dolayısıyla obeziteye diğer fenotiplerden daha yatkındılar. Her 4 fenotipin ortalama sistolik ve diyastolik kan basınçları kontrol grubuna göre anlamlı yüksekti (p<0.05). HOMA indeksi fenotip 1’de en yüksek düzeydi. Metabolik sendrom açısından da fenotip 1 en riskli grubu oluşturmaktaydı (p<0.05). Sonuç: Farklı PKOS fenotipleri arasında klinik, metabolik ve hormonal parametreler yönünden birçok farklılık mevcuttur. Her fenotip için farklı riskler söz konusu olduğundan PKOS tanısı konulurken hastaların hangi fenotipe dahil olduğu uygun şekilde sınıflandırılmalıdır. Bu sayede hastaların karşılaşabilecekleri kısa ve uzun dönemli sağlık riskleri daha iyi hesaplanabili
Social media marketing: A review on instagram
No full textKüreselleşen dünyada teknolojik değişim ve gelişmeler sonucu sosyal medya kavramı ortaya çıkmıştır. Önceleri internet kullanıcıları için sadece eğlence ve paylaşım ortamı olan sosyal medya işletme/marka ve hatta bireyler için ticari pazar özelliğine de kavuşmuştur. Özellikle işletme/markalar Facebook, Instagram vs. sosyal medya platformları aracılığıyla daha geniş hedef kitlelere daha kolay ve hızlı ulaşmaya başlamıştır. Sosyal medya pazarlaması işletme/markalar için geleneksel pazarlama faaliyetlerinin yanı sıra sıklıkla başvurdukları yeni bir pazarlama faaliyeti haline gelmiştir. Bu çalışmanın amacı, sosyal medya pazarlamasının en önemli araçlarından biri haline gelen Instagram uygulaması üzerinden bir inceleme hazırlamaktır. Sözkonusu inceleme için araştırma soruları hazırlanmıştır. Uluslararası marka değerlendirme kuruluşu Brand Finance "Türkiye'nin En Değerli 100 Markası" raporundaki Türkiye'nin marka değeri en yüksek 100 firması içindeki ilk 3 hazır giyim markası Koton, Mavi ve Vakko markaları seçilmiştir. Seçilen markaların Instagram hesapları önceden belirlenen araştırma soruları doğrultusunda 1 Aralık 2020- 1 Nisan 2021 tarihleri arasında incelenmiştir. Elde edilen veriler günlük olarak kaydedilmiştir. Araştırma sonucunda işletme/markaların marka imajlarına ve satışlarına olumlu etkisi olan sosyal medya pazarlaması faaliyetlerine önem vermeye devam etmesi; veriler doğrultusunda Instagram hesap yönetimlerini gerçekleştirmeleri ve Instagram özelinde stratejiler belirlenerek hedef kitlelerine uygun ve Instagram kullanıcılarına özel, yaratıcı, merak uyandıran paylaşımlar yapması önerilmektedir.The concept of social media has emerged as a result of technological changes and developments in the globalizing world. Social media, which was previously only an entertainment and sharing medium for internet users, has also gained the commercial market feature for businesses/brands and even individuals. Especially businesses/brands started to use social media platforms such as Facebook and Instagram etc. in order to reach wider target audiences easier and quicker. Social media marketing has become a new marketing activity for businesses/brands that they frequently apply as well as traditional marketing activities. The aim of this study is to prepare a review on the Instagram application, which has become one of the most important tools of social media marketing. Research questions were prepared for the said study. According to the report of the international brand valuation agency Brand Finance "Turkey's 100 Most Valuable Brands", Koton, Mavi, and Vakko were selected as the top 3 ready-to-wear brands among the 100 companies with the highest brand value in Turkey. The Instagram accounts of the selected brands were examined between 1 December 2020 and 1 April 2021 in line with the predetermined research questions. The obtained data were recorded daily. As a result of the research, businesses/brands continue to attach importance to social media marketing activities that have a positive impact on their brand image and sales; in line with the data, it is recommended that they perform Instagram account management and determine Instagram-specific strategies and make creative, intriguing posts suitable for their target audience and specific to Instagram users