Ufuk Universitesi Akademik Acikerisim Sistemi
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Approaches to preclinical studies with heterogeneous breast phantom using reconstruction and three-dimensional image processing algorithms for diffuse optical imaging
Get PDFThe continuous-wave back reflection diffuse optical tomography (rCWDOT) system is one of the new medical imaging modalities. This study examines the success of reconstruction and three-dimensional (3D) image processing algorithms on data obtained from a heterogonous breast phantom by rCWDOT. Breast phantoms were prepared by putting a bit of spleen inside the tail. The spleen mimics a breast tumor since it has more blood than tail fat. rCWDOT was used to acquire data from the breast phantoms. The breast phantoms were reconstructed using the transpose-free quasi-minimal residual (TFQMR) reconstruction algorithm. Then, image processing algorithms were performed to improve the image quality. In image processing, 3D Gaussian filtering and bi-cubic interpolation were used to enhance the appearance and remove noise from the images. After the image processing, the images were evaluated numerically using the peak signal-to-noise ratio (PSNR) method. It has been shown that the used reconstruction technique and image processing algorithms for a heterogeneous breast phantom provided 3D images that resemble actual ones. This study will help researchers use the most convenient reconstruction algorithm and image processing algorithms and perform preclinical experiments in this field.Turkiye Bilimsel ve Teknolojik Arastirma KurumuTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [110E263]; Akdeniz UniversitesiAkdeniz University [2009.02.0122.003
Psychological Determinants of Entertainment Preferences: From the Perspective of Schema Theory
No full textBackground: The relationship between entertainment preferences and personality traits has previously been addressed in a few studies. However, there are no studies evaluating this relationship within the scope of the schema theory. We planned to evaluate the relationship between early maladaptive schemas (EMS) and music and movie preferences. In this study, the research team created a survey on the 8 most preferred film and music categories in social media platforms in Turkey. Methods: A sociodemographic data form and the Young Schema Questionnaire - Short Form 3 were applied to 389 participants. Our findings emphasize the relationship between EMS, schema domains, and entertainment preferences. Results: In particular, we found significant effects of the Disconnection and Rejection, Impaired Autonomy and Performance, and Impaired Limits schema domains. Even after controlling for age and gender, we found interesting relationships. Conclusion: Early maladaptive schemas have important effects on entertainment preferences. A better understanding of these relationships can provide us with more information on the reflections of personality on daily life
Can serum biochemical markers be used to establish a relationship between idiopathic polyhydramnios and antenatal aneuploidy?
No full textBackground: Polyhydramnios is a common cause of adverse pregnancy outcomes. The prediction of polyhydramnios in early pregnancy may lead to improved treatments and will diminish these adverse outcomes. Objective: This study aims to investigate the role of biochemical markers in antenatal screening tests to predict idiopathic polyhydramnios. Methods: Patient records were retrospectively evaluated in this case-control group study. Pregnant women (160 in total) were included in the study (this included 47 pregnant women diagnosed with idiopathic polyhydramnios and 113 healthy pregnant women as a control group). Results: Alpha-fetoprotein, unconjugated estriol, and total beta-human chorionic gonadotropin values were similar in both groups (p = 0.296, p = 0.573, p = 0.284). There was no significant difference between the group diagnosed with idiopathic polyhydramnios and the control group when the first-trimester screening test parameter, pregnancy-associated plasma protein-A, was examined (p = 0.102). Conclusion: Biochemical markers examined in prenatal screening tests in the first and second trimesters were insufficient to predict idiopathic Polyhydramnios. The reasons for this are that our study was retrospective, and the patient population was low. We believe that a prospective study with a larger population of patients should be conducted for more meaningful results
The duties and powers of public prosecutor during the investigation phase
No full textBu çalışmada Soruşturma aşamasında Cumhuriyet Savcısının görev ve yetkileri konusu incelenmiştir. Birinci bölümde; Cumhuriyet Savcılığına ilişkin temel bilgilere yer verilerek Cumhuriyet Savcılığının konumu, tarihi gelişimi, karşılaştırmalı hukuktaki yeri, teşkilatlanması ve kuruma hâkim olan ilkeler üzerinde durulmuştur. İkinci bölümde; Türk Hukukunda Cumhuriyet Savcısının soruşturma yapma görev ve yetkisi incelenmiştir. Soruşturmaya başlanılması, delil toplanması, koruma tedbirleri ve diğer soruşturma işlemlerine değinilmiştir. Üçüncü bölümde soruşturmanın neticelendirilmesi ve soruşturmayı sonuçlandıran kararlar detaylandırılmıştır. Çalışma boyunca mevzuat, doktrin ve yargı kararlarından yararlanılmıştır.In this study, during the investigation phase, the issue of the duties and powers of the public prosecutor has been examined. In the first part, providing basic information about the public prosecutor's office, its position, historical development, place in comparative law, organisation and the basic principles that govern the institution have been emphasized. In the second part, the duty and authority of the public prosecutor to conduct investigations in Turkish Law has been examined. The initiation of an investigation, collection of evidence, protective measures and the other investigative procedures have been mentioned. In the third part, the conclusion of the investigation and the decisions ending the investigation have been detailed. Throughout the study, legislation, doctrine and judicial decisions have been used
Effectiveness of extracorporeal shock wave therapy in the treatment of epin calcanei
No full textAmaç: Topuk dikeni klinikte sıkça kars?ılas?ılan, kronik plantar topuk ag?rısına neden olan klinik bir tablodur. Hastalara uygulanan kortikosteroid enjeksiyonu, steroid olmayan antiinflamatuvar ilaçlar ve çes?itli fizik tedavi modaliteleri gibi seçeneklerin yanında, Ekstrakorporeal Şok Dalga Tedavisi (Extracorporeal Shock Wave Therapy - ESWT) cerrahi olmayan yöntemler arasında yerini almıs?tır. Bu prospektif kontrollü çalıs?manın amacı klinik ve radyolojik olarak topuk dikeni tanısı alan hastalarda ESWT tedavisinin etkinlig?ini aras?tırmaktır. Gereç-Yöntem: Çalıs?maya klinik ve radyolojik olarak topuk dikeni tanısı konan 49 hasta alındı. Hastalar randomize olarak iki gruba ayrıldı. Grup 1 (n=25) silikon tabanlık kullandı ve dört gün aralıkla 3 seans boyunca 8 Hz frekans ile her seans 1000 atım olacak s?ekilde ESWT tedavisi aldı. Grup 2 (n=24) ise kontrol grubu olarak kabul edildi ve sadece silikon tabanlık kullandı. Ag?rı s?iddeti gece ag?rısı, sabah ilk basma sırasındaki ag?rı, hareket ile ag?rı, istirahat ag?rısı, engebeli zeminde ag?rı ve gün sonunda ag?rı olmak üzere Görsel Analog Skala (GAS) ile ve ayak aktiviteleri ile ilgili fonksiyonel düzey ise Ayak ve Ayak Bileği Sonuç Skoru (Foot and Ankle Outcome Score - FAOS) indeksi ile değerlendirildi. Ölçümler hastalar tedaviye alınmadan önce ve 4 haftalık izlem sonrasında yapıldı. Bulgular: Tedavi sonrasında her iki grupta tüm parametrelerde istatistiksel olarak anlamlı iyiles?me saptandı (p0.05). Sonuç: Çalıs?mamızın sonuçlarına göre ESWT uygulaması topuk dikenine bağlı ağrı semptomunu azaltmada efektif bir konservatif yöntem olarak görülmektedir.Objective: Epin calcanei is a common clinical problem with chronic plantar heel pain. ‘Extracorporeal Shock Wave Therapy (ESWT)’ is a non-surgical method administered to patients along with a variety of other options such as corticosteroid injections, non-steroidal antiinflammatory drugs and physical therapy mo dalities. The aim of this prospective controlled study is to investigate the efficacy of ESWT in patients with clinical and radiological diagnosis of epin calcanei. Materials-Methods: The study included 49 patients diagnosed with epin calcanei according to the clinical and radiological criteria. Patients were randomly divided into two groups. Group 1 (n=25) used silicone insoles and received ESWT treatment as 1000 shots in each session at a frequency of 8 Hz, 3 sessions in total with intervals of four days. Group 2 (n=24) was accepted as the control group and used silicone insoles alone. The severity of pain was evaluated using the pain Visual Analog Scale (VAS) as pain at night, pain in the morning, on the first step, pain on motion, pain at rest, pain on uneven ground and pain at the end of the day. The functional level of activity of the foot was evaluated by the Foot and Ankle Outcome Score (FAOS) index. Measurements were taken before treatment and after 4 weeks of follow-up. Results: After treatment, both groups showed statistically significant improvement in all parameters (p0.05). Conclusion: According to the results of our study, ESWT application is seen as an effective conservative method in decreasing pain related to heel spur
Determination of patient satisfaction in Ankara City Hospital, department of radiation oncology
No full textBu çalışmada Ankara Şehir hastanesinde ayaktan radyoterapi uygulanan 100 hastanın memnuniyetleri değerlendirilmiştir. On sekiz yaş üstü, terminal dönemde olmayan, kanser tanısı olan ve radyoterapi uygulanmakta olan hastalar dahil edilmiştir. Sağlık Bakanlığının standart kullandığı ankete 7 soru daha eklenerek toplam 30 soruluk anket hazırlanmıştır. Hasta memnuniyeti 3'lü Likert ölçeği ile değerlendirilmiştir. Hastaların memnuniyet durumu ve buna etki eden faktörler araştırılmıştır. Hastaların medyan yaşı 59 (21- 86 arasında) dur. Kadın hastalar (%56) çoğunluktadır. Akciğer kanserli hastalar en büyük grubu (%33) oluşturmaktadır ve evre 3 hastalık en sıktır (%38). IMRT tekniği de %65 oranında tercih edilmiştir. Medyan toplam memnuniyet skoru %96.6 olarak hesaplanmıştır. Memnuniyeti etkileyen faktörlere bakıldığında hastaların eğitim durumu (p=0.011) ve daha önce tedavi almış olması (p=0.019) önemli bulunmuştur. Radyoterapi bölümünden memnuniyet oranı medyan %100 (%81-%100 aralığında) bulunmuştur. Hastaneye birden çok başvuran hastaların istatistiki olarak önemli ölçüde daha memnun oldukları gözlenmiştir (P=0.031). RT tekniğinin memnuniyeti sınırlı düzeyde etkilediği görülmüştür (P=0.069). Ankara Şehir Hastanesi'nde RT uygulanan hastalar üzerinde yapılan bu çalışmada, sunulan hizmetlerin hasta beklentilerini karşıladığını göstermektedir.Patient satisfaction survey was performed on 100 out-patient radiotherapy patients at Ankara City Hospital. Patients more than 18 years of age, who have diagnosis of cancer, not at the terminal stage were included in the study. Survey is prepared by adding 7 questions to standard Ministry of Health survey. Patient satisfaction was evaluated by 3 points Likert scale. Patient satisfaction and influential factors were evaluated. Median patient age was 59 (between 21-86). Female patients were larger group (56%). Lung cancer patients were the biggest group (33%) and stage 3 diagnosis was the most frequent (38%). IMRT was preferred technique in 65% of the cases. Median satisfaction score was 96.6%. The factors that effect the satisfaction were patient education (P=0.011) and history of previous treatments (P=0.019). Patient's satisfaction with the radiotherapy department was median 100% (81-100 %). Patients with previous admission to the hospital were significantly more satisified (P=0.031). Radiotherapy technique was borderline significance on Patient's satisfaction (P.0.069). This study that was performed in Ankara City Hospital, showed patients were satisfied with the provided health services
Comparison of Dementia Patients Admission Rates and Dementia Characteristics Before and During the COVID-19 Pandemic
No full textBackground The coronavirus disease 2019 (COVID-19) epidemic was recognized as a pandemic by the World Health Organization on March 2020. There have been significant changes in our lives due to the measures used to prevent the spread of the COVID-19 pandemic. Dementia patients are one of the most vulnerable groups who have difficulties in adapting to this situation. Our study aimed to compare the admission rate to the hospital and dementia characteristics of dementia patients in the COVID-19 pandemic and pre-pandemic periods. Methods Dementia patients admitted to the neurology outpatient clinic during the pandemic and pre-pandemic periods were included in the study. In these two periods, age, gender, dementia type, stage, age of onset, mini-mental state examination, reason for admission, vitamin B12, vitamin D, folk acid levels, brain imaging, electroencephalogram results were analysed retrospectively. Dementia characteristics and vitamin levels were compared. Results Two hundred and two dementia patients were included in the study. When the reasons for admission to the hospital were examined, the number of applications with the complaint of forgetfulness was highest in the pre-COVID period (53.1%); this rate was 37.8% in the COVID period. Also, 9.5% of patients were admitted for a drug prescription or medication report during the COVID period, while this rate was 1.6% in the pre-COVID period. Brain imaging was performed on 91 patients in the pre-COVID period, while 42 patients underwent imaging in the COVID period. Conclusions Although this study was performed with a limited population, it indicates that the COVID-19 pandemic indirectly affects the clinical conditions of people living with dementia
Apolipoprotein E and adiponectin levels in coronary artery disease patients with low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol discordance
No full textObjectives: The aim of this study was to investigate whether serum apolipoprotein E (ApoE) and adiponectin were as sociated with discordance of low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) levels in coronary artery disease (CAD) patients. Methods: A total of 243 patients with significant CAD were studied. The fasting levels of serum lipids, plasma ApoE, and adiponectin were measured. The median LDL-C and non-HDL-C values were determined to assess and analyze discordance. Discordance was defined as an LDL-C? the median and non-HDL-C< the median, or an LDL-C< the median and a non-HDL-C? the median. ApoE and adiponectin were compared between discordant and concordant groups. Results: Discordance between the LDL-C and the non-HDL-C was observed in 14% of the patients. Although the me dian adiponectin was lowest in the group with an LDL-C< median and a non-HDL-C? the median, and the median ApoE was lowest in the group with an LDL-C? median and a non-HDL-C< the median, no statistically significant differences in the ApoE and adiponectin were recorded between the groups (p=0.186 and p=0.161, respectively). Adiponectin was negatively correlated with triglyceride and remnant cholesterol (p<0.001 and p<0.001, respectively). Conclusion: While discordance between the LDL-C and the non-HDL-C in CAD patients (14%) was observed, the plas ma ApoE and adiponectin levels were not significantly different between the discordant and concordant groups
Validity and reliability of the Turkish version of the Shoulder Rating Questionnaire in patients with shoulder pain
Get PDFObjectives: The aim of this study was to translate the Shoulder Rating Questionnaire (SRQ-T) into Turkish and to determine the
validity and reliability of the translated version in patients with shoulder pain.
Methods: The Turkish version of the SRQ-T was applied to patients after translation from English into Turkish. Patients with
various shoulder pain complaint were included into the study if they were over 18 years. The patients with mixed-type pain,
cancer pain, headache, substance abuse, severe depression, and fibromyalgia syndrome were excluded. The musculoskeletal
and neurological examinations of the patients were performed. The Turkish version of the SRQ-T and Disabilities of arm,
shoulder, hands-T (DASH-T) were applied to all patients.
Results: 122 patients were included in the study, and then patients are divided into two groups: Group 1, working group (n = 72);
Group 2, non- working group (n = 50). The reliability and consistency of SRQ-T for all the samples were acceptable with a
Cronbach’s coefficient of 0.979. The test-retest method was used to determine reliability of the scale. Cronbach’s alpha was
measured pre-assessment and post- assessment; the values were 0.815 and 0.770, respectively. The correlation analysis was
determined for all the samples and calculated as 0.780. Also, the test-retest method with Wilcoxon Signed Rank Test was used to
determine reliability of the SRQ- T and its domains in group 1 and group 2.
Conclusion: The Turkish version of the SRQ-T seems to be a valid and reliable self-administered questionnaire to evaluate the
shoulder pain in Turkish patient
The utility of immunoglobulin A/complement 3 and immunoglobulin G/immunoglobulin M ratios in the assessment of disease activation in patients with Behcet disease
Get PDFObjective: Pathogenesis of Behc¸et disease (BD) has not yet been clearly revealed and there is no ideal
test for the estimation of disease activation at present. This study aimed to assess the efficiencies of
IgG/IgM and IgA/C3 ratios in determining activation of BD.
Method: This retrospective cohort study consisted of 140 patients with BD. Patients were divided into
two groups: (1) active BD (n ¼ 89) and (2) inactive BD (n ¼ 51) and were compared in terms of demo graphic features, clinical characteristics and laboratory test results. IgA/C3 and IgG/IgM ratios were
compared according to organ system involvement; receiver operating characteristic (ROC) curve ana lysis was performed in order to assess the performance of IgA/C3 and IgG/IgM ratios in determining
patient disease status.
Results: Significantly higher levels of erythrocyte sedimentation rate, C-reactive protein, IgA, G, C4,
IgA/C3, IgG/IgM ratios (p ¼ .007 for IgA and p < .001 for others) and significantly lower levels of IgM
and C3 were observed in patients with active BD (p < .001). The IgG/IgM ratio was significantly higher
in patients with vascular involvement (p ¼ .017) and the IgA/C3 ratio was significantly higher in
patients with arthritis (p ¼ .007). Cut-off values of 0.019 (70.8% sensitivity, 62% specificity) and 7.08
(84.3% sensitivity, 80% specificity) were determined for IgA/C3 and IgG/IgM ratios, respectively.
Conclusion: IgA/C3 and IgG/IgM ratios may be used as additional parameters for the assessment of
BD status