Ufuk Universitesi Akademik Acikerisim Sistemi
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THE IMPACT OF CONTACT LENS DURATION ON OCULAR DISCOMFORT
No full textObjectives: To compare contact lens discomfort (CLD) using the Contact Lens Dry Eye Questionnaire-8 (CLDEQ8) in short and long-term CL wearers. Materials and Methods: This prospective study included 98 patients who applied to the Department of Ophthalmology of Ufuk University between January 2020 and January 2021 and had a history of wearing contact lenses for over a month. Participants who wore contact lenses (CL) for six months or less were categorized as short-term CL users, while those who wore them for more than six months were categorized as long-term CL users. Contact lens compliance and the CLDEQ-8 questionnaire results were compared between the groups. Results: The mean age was 21.70±2.81 years in 55 short-term CL wearers, and 80% were female. In 43 long-term CL wearers, the mean age was 28.69±8.48 years, and 86% were female (respectively, p<0.001, p=0.592). The duration of CL wear was 2.36±1.06 months in short-term CL wearers and 10.11±5.6 months in long-term CL wearers (p<0.001). The mean CLDEQ-8 score was 11.52±6.59 in short-term CL wearers and 14.37±6.55 in long-term CL wearers (p=0.015). In addition, 40% of short-term and 65.1% of long-term users had a CLDEQ-8 score greater than 12 (p=0.016). Conclusion: Long-term CL wearers experienced much more CLD, and several considered removing their lenses at various times. Contact lens discomfort has to be investigated, especially in long-term CL users, and solutions should be developed to avoid CL dropout. © Annals of Translational Medicine. All rights reserved
Comparison of kinesio taping, trigger point injection, and neural therapy in the treatment of acute myofascial pain syndrome: A randomized controlled study
No full textObjectives: Myofascial pain syndrome (MPS) is a regional painful soft-tissue disorder, characterized by trigger points (TrPs) and taut bands in the muscles. In this study, we aimed to compare the effectiveness of kinesio taping (KT), TrPs injection, and neural therapy (NT) on pain and disability in acute MPS.Methods: 104 patients with MPS in the cervical region were allocated into three groups. Group 1 (n=35) were treated with KT, Group 2 (n=35) received local anesthetic (LA) (lidocaine of 0.5%) TrPs injection, and Group 3 (n=34) received NT with the same LA solution. Patients were assessed by means of pain, pressure pain threshold (PPT), and disability. Pain severity was measured by Visual Analog Scale. The neck pain disability scale was used for assessing disability. PPT was measured by using an algometer. Measurements were taken before and after treatment of 3(rd) and 7(th) days.Results: There were improvements on pain and disability in all groups at the end of treatments at 3(rd) day and during follow-up period (p<0.001) and no differences were found between the groups. There was significant difference in PPT values in TrPs injection and NT groups in comparisons between all time periods, however, the change, depending on time in the KT group, was not statistically significant.Conclusion: The results of this study show that all these three treatment methods found to be effective on pain relief and disability in acute MPS. In terms of PPT, injection treatments seem to be superior than KT
Evaluation of abdominal computed tomography findings in patients with COVID-19: a multicenter study
No full textPURPOSETo evaluate the frequency of abdominal computed tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19) and interrogate the relationship between abdominal CT findings and patient demographic features, clinical findings, and laboratory test results as well as the CT atheroscle-rosis score in the abdominal aorta.METHODSThis study was designed as a multicenter retrospective study. The abdominal CT findings of 1.181 patients with positive abdominal symptoms from 26 tertiary medical centers with a positive polymerase chain-reaction test for severe acute respiratory syndrome coronavirus 2 were reviewed. The frequency of ischemic and non-ischemic CT findings as well as the association between CT findings, clinical features, and abdominal aortic calcific atherosclerosis score (AA-CAS) were recorded.RESULTSIschemic and non-ischemic abdominal CT findings were detected in 240 (20.3%) and 328 (27.7%) patients, respectively. In 147 patients (12.4%), intra-ab-dominal malignancy was present. The most frequent ischemic abdominal CT findings were bowel wall thickening (n = 120; 10.2%) and perivascular infil-tration (n = 40; 3.4%). As for non-ischemic findings, colitis (n = 91; 7.7%) and small bowel inflammation (n = 73; 6.2%) constituted the most frequent disease processes. The duration of hospital stay was found to be higher in patients with abdominal CT findings than in patients without any positive findings (13.8 & PLUSMN; 13 vs. 10.4 & PLUSMN; 12.8 days, P < 0.001). The frequency of abdominal CT findings was significantly higher in patients who did not survive the infection than in patients who were discharged after recovery (41.7% vs. 27.4%, P < 0.001). Increased AA-CAS was found to be associated with a higher risk of ischemic conditions in abdominal CT examinations.CONCLUSIONAbdominal symptoms in patients with COVID-19 are usually associated with positive CT findings. The presence of ischemic findings on CT correlates with poor COVID-19 outcomes. A high AA-CAS is associated with abdominal ischemic findings in patients with COVID-19
Effects of Sildenafil Citrate on Ipsilateral Testis Damage Following Experimental Testicular Torsion in Rats
No full textObjective: Testicular torsion results in damage of the gonad and represents surgical emergency. Testicular torsion induces sterility as a result of ischemia. The aim of this study was to determine the effects of a vasodilator agent sildenafil on the testicular damage following testicular torsion. Methods: Forty-two Wistar-albino male albino rats were divided into seven groups, each containing six rats. C: Control, S: Sham (operative procedure without torsion), T: Torsion (detorsion was performed 2 hours after 720 degrees left testis torsion and orchiectomy was done at the 4th hour.), Sildenafil (Viagra; Pfizer) was given without torsion to V1 group and V2 group (respectively 1 mg/kg and 2 mg/kg). Sildenafil was given to V1T group and V2T group respectively 1mg/kg and 2mg/kg at the first hour following torsion then detorsion was performed 2 hours after torsion and orchiectomy was done at the 4th hour. At the end of the study blood and testes tissue samples were obtained for malonyldialdehyde (MDA), nitric oxide (NO), Johnsen tubuler biopsy score (JTBS) and diameter of seminiferous tubule (STD) analysis. Results: JTBS and STD levels were highest in the C group and the lowest T Group and torsion reduced spermatogenesis significantly compared to the C and S groups (p < 0.05). Sildenafil administration without torsion (V1 and V2) did not change JTBS scores. JTBS levels of the V2T group were increased significantly when compared to V1T (p < 0,05). C compared to study groups showed statistically different changes in terms of STD (p < 0,05). Torsion reduced STD significantly compared to the C and S group (p < 0,05). Tissue and plazma MDA levels were the highest in the V2T group and the lowest C Group. Tissue NO levels were the highest in the V1T group and lowest in C Group. Sildenafil administration (1 mg/kg and 2 mg/kg) without torsion group compared to torsion groups in terms of plasma and testis tissue MDA and NO levels showed significantly statistically different changes. Conclusion: Sildenafil showed a protective effect against tubular damage histologicaly after unilateral torsion and detorsion.Scientific Research Foundation of Gazi University [01/2002-119]This study was sponsored by the Scientific Research Foundation of Gazi University (01/2002-119)
Comparison of Pain Catastrophic Scale and Anxiety in Patients With Boxer's Fracture and Other Types of Hand Fractures
No full textObjective: The Pain Catastrophic Scale (PCS) is generally associated with high and low post-recovery satisfaction and measures the pain perception of patients in the literature. This study aims to evaluate the association of deliberate (as in a fight or anger causing punching a wall) boxer's fractures with catastrophic pain compared to accidental (as in a fall, accidental knocking it against a wall, etc.) fractures and evaluate the effect of anxiety about fracture union and functional recovery on clinical outcomes.Materials and methods: A total of 62 male patients with metacarpal fractures, 31 as a result of deliberate punching (1st group) and 31 with metacarpal fractures as a result of an accident (2nd group), who applied to the emergency department or orthopedic clinic with the diagnosis of metacarpal fracture between January 2021 and October 2022, were included in the study. All patients were selected from patients who were followed up with conservative plaster/splint. The PCS scores of the patients were evaluated comparatively with the clinical results measured after at least six weeks.Results: The mean age of the patients was 30.8 (18-50) in the 1st group and 34.8 (18-64) in the 2nd Group, and no statistically significant difference was found (p=0.274). While the median PCS score was 10.5 (interquartile range {IQR}: 12.3) for the 1st group, the median PCS score was 17.5 (IQR: 14.5) for the 2nd group, and the PCS score was statistically significantly lower in group 1 (p=0.009). While the median Visual Analogue Scale (VAS) value was 0 (IQR: 0.3) for the 1st group, the median VAS value was 1 (IQR: 2.0) for the 2nd group, and the VAS score was statistically significantly lower in the 1st group (p<0.001). While the median 'quick disabilities of the arm, shoulder, and hand' (Q-DASH) value was 0 (IQR:2.3) for the 1st group, the median Q-DASH value was 3.4 (IQR:6.3) for the 2nd group, and the Q-DASH score was statistically significantly lower in the 1st group (p=0.001). No significant difference was observed between the 1st and 2nd groups in terms of grip strength values (p=0.815). Conclusion: The etiology of patients presenting with a boxer's fracture should be well understood, and if necessary, these patients should be treated multidisciplinary, with psychiatric help. Better satisfaction can be achieved with lower results in patients whose PCS scoring system has lost its eigenvalue
The diagnosis of femoroacetabular impingement can be made on pelvis radiographs using deep learning methods
No full textObjectives: The aim of this study was to evaluate diagnostic ability of deep learning models, particularly convolutional neural network models used for image classification, for femoroacetabular impingement (FAI) using hip radiographs. Materials and methods: Between January 2010 and December 2020, pelvic radiographs of a total of 516 patients (270 males, 246 females; mean age: 39.1 +/- 3.8 years; range, 20 to 78 years) with hip pain were retrospectively analyzed. Based on inclusion and exclusion criteria, a total of 888 hip radiographs (308 diagnosed with FAI and 508 considered normal) were evaluated using deep learning methods. Pre-trained VGG-16, ResNet-101, MobileNetV2, and Inceptionv3 models were used for transfer learning. Results: As assessed by performance measures such as accuracy, sensitivity, specificity, precision, F-1 score, and area under the curve (AUC), the VGG-16 model outperformed other pre-trained networks in diagnosing FAI. With the pre-trained VGG-16 model, the results showed 86.6% accuracy, 82.5% sensitivity, 89.6% specificity, 85.5% precision, 83.9% F1 score, and 0.92 AUC. Conclusion: In patients with suspected FAI, pelvic radiography is the first imaging method to be applied, and deep learning methods can help in the diagnosis of this syndrome
Impact of VieScope? on first-attempt success during simulated COVID-19 patients intubation: A randomized cross-over simulation trial
No full textBACKGROUND: The purpose of our study was to determine the efficacy of intubation with VieScope (R) and Macintosh laryngoscope in different scenarios of simulated COVID-19 patients by paramedics wearing personal protective equipment (PPE) for aerosol generMETHODS: Study was designed as a prospective, observational, randomized, crossover simulation trial. 37 paramedics took part in the study. They performed endotracheal intubation (ETI) of a person suspected of COVID-19. Intubation was performed using VieScope (R) and Macintosh laryngoscopes in two research scenarios: Scenario A - normal airway and Scenario B - difficult airway. Both theRESULTS: In Scenario A, time to intubation using VieScope (R) and Macintosh laryngoscope amounted to 35.3 (IQR; 32-40) seconds and 35.8 (IQR: 30-40)s, respectively. Nearly all participants performed ETI successfully both with VieScope (R) and Macintosh laryngoscope (100% vs. 94.6%). In scenario B, intubation with the VieScope (R), compared to the Macintosh laryngoscope, was associated with a shorter intubation time (p<0.001), a higher success rate of the first intubation attempt (p<0.001), a better visualization degree glottisCONCLUSION: Our analysis suggests that the use of a VieScope (R) compared to Macintosh laryngoscope in difficult airway intubation performed by paramedics wearing PPE-AGP is associated with shorter intubation times, greater intubation efficiency as well as better visualization of the glottis. Additional clinical trials are necessary to confirm the obtained results
Facial emotion recognition in adolescent depression: The role of childhood traumas, emotion regulation difficulties, alexithymia and empathy
No full textIntroduction: Facial emotion recognition (FER) is crucial for effective social competency, and problems in this skill are linked depression during adolescence. In this study, we aimed to find the rates of FER accuracy for negative (fearful, sad, angry, disgusted), positive (happy, surprised), and neutral emotions, and the possible predictors of FER skill for most confusing emotions. Subjects and Methods: A total of 67 drug-naive adolescents with depression (11 boys, 56 girls; 11-17 years) were recruited for the study. The facial emotion recognition test, childhood trauma questionnaire and basic empathy, difficulty of emotion regulation, and Toronto alexithymia scales were used. Results: The analysis demonstrated that adolescents have more difficulties in recognizing negative emotions when compared the positive ones. The most confusing emotion is fear (39.8% of fear was recognized as surprise). Boys have lower fear recognition skill than girls and higher childhood emotional abuse, physical abuse, emotional neglect, and difficulty in describing feelings to predict lower fear recognition skill. For sadness recognition skill, emotional neglect, difficulty in describing feelings, and depression severity were the negative predictors. Emotional empathy has a positive effect on disgust recognition skill. Conclusion: Our findings demonstrated that impairment of FER skill for negative emotions is associated with childhood traumas, emotion regulation difficulties, alexithymia, and empathy symptoms in adolescent depression
Association between vascular calcification, atherosclerosis and inflammatory markers in end-stage renal disease patient and simple method for detecting vascular calcification (direct radiography)
No full textPurpose: In our study, we planned to investigate the relationship of malnutrition with inflammation, atherosclerosis and calcification in dialysis patients. Materials and methods: 140 Chronic kidney disease (CKD) patients and 44 healthy controls were included in the study. Carotid artery intima-media thickness (CIMT) was measured by doppler ultrasonography. Valvular calcification was assessed by echocardiography and vascular calcification scores (VCS) were done based on the radiograms. Biochemical parameters were assessed using routine laboratory methods. Subjective global assessment (SGA) was used to evaluate malnutrition. Results: In the study, VCS showed no differences between hemodialysis (HD) and peritoneal dialysis (PD) patients (1.84±2.35 for HD, 1.77±1.64 for PD; p=0.83). CIMT, Osteopontin (OPN), interleukin-6 (IL-6) and homocysteine were significantly different in both dialysis groups compared to healthy controls. The Mean carotid intima-media thickness (m-CIMT) was higher in HD patients compared to PD group. CIMT, vascular calcification and SGA scores showed positive correlation with age, dialysis duration and valvular calcification grades, and negative correlation with albumin levels. A positive correlation between SGA scores and high-sensitive C-reactive protein (hs-CRP) levels was also noted. On multiple regression analysis, m-CIMT was independently associated with age, VCS and albumin levels. VCS was found to be independently associated with only albumin levels. Conclusion: Vascular and valvular calcification, an indicator of cardiovascular mortality and morbidity in dialysis patients, was found to be significantly associated with malnutrition. We found higher rates of valvular calcification in patients with vascular calcification. Malnutrition was more prominent in these patients
ENGLISH INSTRUCTORS’ PERCEPTION RELATED TO PROFESSIONAL DEVELOPMENT: A CASE STUDY IN A FOUNDATION UNIVERSITY
No full textOver the past decades, the importance given to Teacher Professional Development (TPD) activities and opportunities have been undoubtedly increasing day by day all around the world. As every living thing in the world is evolving, a language itself, a living phenomenon, is assuredly evolving which means that educators face new challenges they have to come up with new solutions for and adapt. The study aims to investigate the English language teachers’ perceptions with regards to teacher professional development and its related options. For that purpose, in the study, the sequential method was adopted. The participants were composed of 20 full-time instructors (16 female, 4 male) working in a foundation university in Turkey as English instructors. The data were collected using via both a questionnaire developed by Eksi (2010) and a follow-up interview. For follow-up interview, the respondents were gathered of 5 full-time instructors determined by simple random sampling method. The data obtained from the questionnaire were analyzed using Statistical Package for the Social Sciences (SPSS) Version 25 and the data from the follow-up interview were coded and were analyzed by carrying out inductive content analysis