Jurnal Health Sains (JHS)
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The Effect of the Ketogenic Diet on Weight Loss and Metabolic Risk Factors: A Systematic Review and Meta-Analysis
Full text linkObesity remains a major global health problem with increasing prevalence, leading to a rise in the use of dietary interventions such as the ketogenic diet. Despite its popularity, evidence regarding its effectiveness in improving metabolic parameters remains inconsistent. This study aimed to evaluate the impact of the ketogenic diet on weight loss and metabolic risk factors through a systematic review and meta-analysis. Following the PRISMA 2020 guidelines, relevant studies were retrieved from PubMed, ScienceDirect, Cochrane Library, and ProQuest databases. Eligible randomized controlled trials assessing the effects of the ketogenic diet on glucose control, blood pressure, body mass index (BMI), and lipid profiles in obese patients were included. Data extraction and quality assessment were conducted using the Risk of Bias (RoB) tool, and statistical analyses were performed with Review Manager v5.3. Nine eligible studies (n = 437 participants) were included. The ketogenic diet significantly reduced blood glucose levels (SMD = -0.27 mg/dL, 95% CI: -0.50 to -0.04, P = 0.02) and triglycerides (SMD = -28.38 mg/dL, 95% CI: -32.07 to -24.69, P < 0.001), while increasing LDL cholesterol (SMD = 17.27 mg/dL, 95% CI: 1.10 to 33.44, P = 0.04). However, no significant changes were observed in BMI, HDL, total cholesterol, or blood pressure. Funnel plot and Egger’s test results indicated no publication bias. In conclusion, the ketogenic diet demonstrates beneficial effects on glucose regulation and triglyceride reduction but has limited efficacy for weight loss and may elevate LDL levels, warranting cautious clinical application in obesity management
Manual Aid in the Vaginal Delivery of Spontaneous Twin Cephalic-Complete Breech Pregnancy: A Case Report
Full text linkMultiple gestation, particularly those involving a combination of breech and cephalic presentations, presents a complex obstetric challenge. This case report describes the successful vaginal delivery of a twin pregnancy with mixed presentation at 36/37 weeks of gestation. A 28-year-old woman, G2P1A0, presented in active labor with a cervical dilation of 4 cm. The first twin was in cephalic presentation, while the second was in breech. Following the NICE guidelines for twin delivery with a cephalic-presenting first twin, a vaginal delivery was planned. The first baby was delivered spontaneously. For the second, breech-presenting twin, an amniotomy was performed, followed by a Manual Aid for Breech Delivery, resulting in a safe vaginal birth. Both infants had satisfactory Apgar scores, and the third stage was managed without significant postpartum haemorrhage. This case demonstrates that with careful monitoring and skilled intervention, vaginal delivery is a viable and safe option for twin pregnancies with a cephalic-breech combination, potentially avoiding the need for cesarean section. The successful outcome underscores the importance of preparedness for breech extraction and holistic management during the intrapartum and postpartum periods
Empowering Cadres In Preparing The Community To Face The New Normal Era In Jabungan Banyumanik Village, Semarang City
Full text linkSpecial attention to health issues is still the main focus of the government in Indonesia. Some health aspects that are of concern include health degrees, cross-sectoral cooperation, health development policies, health development financing systems, quality of health facilities, health workers, and health supplies (Suparyanto, 2010). These health problems can affect the general public as well as certain groups such as infants, toddlers, pregnant women, the elderly, and workers. The purpose of this study is to run the Tri Darma of higher education by implementing community service activities, especially in the form of preparing health cadres to face the New Normal Era in Jabungan Banyumanik Village, Semarang City. The implementation method includes a preparatory stage that involves coordinating with health cadres, identifying participants, compiling materials, and carrying out activities using lectures, demonstrations, and discussion methods. Evaluation is carried out through pretest and posttest to measure the increase in cadre knowledge. Findings from the study showed that there was an increase in cadre knowledge by 15%. The impact of this research is improving the quality of health cadres, public understanding of the New Normal Era, and strengthening cooperation between universities and the community. Therefore, increasing the knowledge and skills of cadres, as well as community understanding, is expected to have a positive impact on health services and preparation for new situations
The Relationship of Smoking Status and Ventilation Extent with The Incident of Tuberculosis
Full text linkTuberculosis is an infectious disease caused by the bacterium Mycobacterium Tuberculosis and attacks the organs or tissues of the human body, especially the lungs, which is caused by an imbalance between the environment, agent and host. Factors that can cause the spread of tuberculosis, if treatment is not carried out quickly, will cause an increase in the number of cases of tuberculosis. The aim of this research is to analyze the relationship between family smoking status and ventilation area with the incidence of tuberculosis in the working area of the Banjarejo Community Health Center, Madiun City. In this research, researchers used quantitative research as an approach. The research method used is an analytical survey while the type of research is Case Control. The total population was 35 tuberculosis cases with a sample size of 52 respondents who were divided between the case group and the control group using the Chi-Square test. The results of the study showed that there was a significant relationship between the independent variables of family smoking status (p-value = 0.018), ventilation area (p-value = 0.007) with the incidence of tuberculosis in the working area of the Banjarejo Community Health Center, Madiun City
The Relationship Between Glycemic Control And Lipid Profile In Patients With Type 2 Diabetes Mellitus In Bangli Hospital
Full text linkType 2 diabetes mellitus (DM) is prone to diabetic dyslipidemia which is one of the factors in increasing the risk of cardiovascular disease complications. The purpose of this study was to determine the relationship between glycemic control and lipid profile in patients with type 2 DM. Research with a cross-sectional study was conducted at the Internal Medicine Polyclinic of Bangli Hospital in the period January 2023-December 2023 and as many as 60 patients with type 2 DM who met the inclusion criteria. Patients were grouped into type 2 DM patients with controlled glycemic control (HbA1c <7%) and uncontrolled (HbA1c ≥7%). Lower levels of total cholesterol (160,444 ± 30,608 mg/dl vs 203,476 ± 45,471 mg/dl; p = 0.001), triglycerides (125,500 ± 56,019 vs 202,047 ± 91,568; p = 0.002), low-density lipoprotein (K-LDL) (93,072 ± 28,443 vs 131,571 ± 44,590; p = 0.001) in type 2 DM patients with controlled glycemic control. High-density lipoprotein (K-HDL) levels (50,022 ± 14,050 vs 41,152 ± 12,619; p = 0.019) were higher in type 2 DM patients with controlled glycemic control. Statistical tests showed a positive correlation between total cholesterol (r = 0.277; p = 0.032), triglyceride (r = 0.386; p = 0.002) and K-LDL (r = 0.357; p = 0.005) levels with HbA1c levels. There was a negative correlation between K-HDL (r=-0.366; p=0.004) and HbA1c levels. The significant correlation between HbA1c and lipid profile shows the importance of glycemic control in type 2 DM patients. This can be explained in the pathogenesis of type 2 DM during the advanced phase. There was a positive correlation between glycemic control (HbA1c) with total cholesterol, triglycerides and K-LDL. There is a negative correlation between glycemic control (HbA1c) and K-HDL
Analysis of Factors Affecting The Body Temperature of Postoperative Patients At RSUP Dr. M Djamil Padang
Full text linkIntroduction: Surgery is a medical procedure carried out using invasive methods by opening, cutting or slashing parts of the body to provide treatment to the patient. Changes in body temperature can occur in post-operative patients which are influenced by age, gender, body mass index (BMI), duration of surgery, and type of surgery. Objective: To analyze the factors that influence the body temperature of post-operative patients at RSUP Dr. M. Djamil Padang. Methods: This study is a correlative analytical research using cross sectional design. This study was conducted using primary data and the samples were selected by consecutive sampling technique with a total of 56 samples. Results: The results of this study show that there is a relationship between age with body temperature of the patients after surgery (p=0,021, r=-0,308), there is no relationship between gender with body temperature of the patients after surgery (p=0,876, r=0,021), there is a relationship between BMI with body temperature of the patients after surgery (p=0,033, r=0,140), there is a relationship between duration of surgery with body temperature of the patients after surgery (p=0,027, r=-0,482), and there is no relationship between type of surgery with body temperature of the patients after surgery (p=0,762, r=0,041). Conclusion: There is a significant relationship between age, BMI and duration of surgery with body temperature of the patient's after surgery and there was no significant relationship between gender and type of surgery with body temperature of the patient's after surgery
Herbal For Anxiety In Psychology Case: Bibliometric Analysis
Full text linkThis research aims to carry out an in-depth analysis of the effects of herbs on anxiety in psychological cases. In order to address the complex character of anxiety disorders, there is a link between herbal therapies for anxiety in psychological cases and the integration of psychological and herbal viewpoints. Herbal treatments provide supplementary options for modifying neurobiological mechanisms underpinning symptom presentation, whereas psychological therapies focus on the cognitive, emotional, and behavioural elements of anxiety. Bibliometric analysis was done using VOSviewer software, and data was taken from the Scopus database. Data was taken by searching for keywords that were appropriate to this research, namely "herbal,” “anxiety,” and “psychology.”Herbal remedies are a viable means of supplementing psychological therapy and fostering overall well-being while reducing anxiety in psychological problems. In psychological circumstances, the link between herbal therapies for anxiety entails integrating herbal and psychological viewpoints to address the intricate interaction of behavioural, affective, cognitive, and neurobiological components that underlie anxiety disorders. Healthcare professionals should stay up to date on the growing body of research supporting herbal therapies and participate in collaborative decision-making with patients on available treatments, taking into account each patient's unique preferences, values, and cultural beliefs. The research's methodological approach, which combines bibliometric analysis with data retrieved from the Scopus database, offers a methodical and objective way to compile the body of knowledge on herbal remedies for anxiety in psychiatric problems
Analysing the Spiritual Effects of Emotional Freedom Technology (SEFT) in Building Psychological Well-being: Systematic Literature Review
Full text linkSpiritual emotional freedom techniques (SEFT) influence psychological well-being because psychological well-being is an individual's ability to prosper with all one's abilities and weaknesses cope with life's stresses, can work productively and fruitfully. The method used is a systematic literature review by collecting various literature, namely Scopus, and PubMed. Using SEFT keywords; psychological well-being, effects. The results of several studies indicate that there is an influence of SEFT in developing psychological well-being. SEFT is carried out with the power of prayer and tapping at several points will influence the level of stress. SEFT therapy can be applied in the field of clinical practice to support patient care
Adjuvant Therapy Effect of Curcuma Longa Rhizome Extract On TGF-β Serum Levels in Leprosy Ulcer Patients
Full text linkLeprosy ulcer is one of the worsening manifestations of leprosy that often causes disability if not appropriately handled. Healing of ulcers requires a long enough duration so that a good immunological response is needed to encourage the wound healing process, one of which is transforming growth factor- (TGF-), which is necessary of the plants that plays a role in the expression of TGF- to spur wound healing is Curcuma longa rhizome or turmeric rhizome. This study is expected to prove that administering Curcuma longa rhizome extract can increase serum TGF-β levels in leprosy ulcer patients. This study is an experimental study with a pre and post-randomised single-blind controlled trial design involving 22 subjects with leprosy ulcers. The control group obtained standard therapy for leprosy ulcers, and the treatment group received standard therapy and adjuvant Curcuma longa rhizome extract at a dose of 1 g per day for 30 days. TGF-β levels were measured by the ELISA method. Data analysis used the Wilcoxon test and the Mann-Whitney test. The results showed no significant difference in TGF-β levels after and before the intervention in the control group (p=0.79) and the treatment group (p=0.14). However, there was a significant difference in TGF-β levels after the intervention in the control group and treatment (p=0.01). Curcuma longa rhizome extract did not show an important role in changes in serum TGF-β levels in leprosy ulcer patients. This study showed that administering Curcuma longa rhizome extract for 1 month did not show a potential role as an adjuvant therapy.
Leprosy ulcer is one of the worsening manifestations of leprosy that often causes disability if not appropriately handled. Healing of ulcers requires a long enough duration so that a good immunological response is needed to encourage the wound healing process, one of which is transforming growth factor- (TGF-), which is necessary of the plants that plays a role in the expression of TGF- to spur wound healing is Curcuma longa rhizome or turmeric rhizome. This study is expected to prove that administering Curcuma longa rhizome extract can increase serum TGF-β levels in leprosy ulcer patients. This study is an experimental study with a pre and post-randomised single-blind controlled trial design involving 22 subjects with leprosy ulcers. The control group obtained standard therapy for leprosy ulcers, and the treatment group received standard therapy and adjuvant Curcuma longa rhizome extract at a dose of 1 g per day for 30 days. TGF-β levels were measured by the ELISA method. Data analysis used the Wilcoxon test and the Mann-Whitney test. The results showed no significant difference in TGF-β levels after and before the intervention in the control group (p=0.79) and the treatment group (p=0.14). However, there was a significant difference in TGF-β levels after the intervention in the control group and treatment (p=0.01). Curcuma longa rhizome extract did not show an important role in changes in serum TGF-β levels in leprosy ulcer patients. This study showed that administering Curcuma longa rhizome extract for 1 month did not show a potential role as an adjuvant therapy
Effect of Curcuma longa Extract as Adjuvant Therapy on IL-6 Serum Levels in Leprosy Type 1 Reaction Patients
Full text linkType 1 leprosy reaction / Reversal reaction (RR) is an inflammatory episode in existing leprosy lesions and aggravates the pain rate. Long-term therapy with steroids causes a variety of side effects, so an adjuvant therapy alternative is needed to alleviate steroid use. Curcuma longa rhizome extract has become an anti-inflammatory therapy choice in various previous inflammatory diseases. This study aims to determine the anti-inflammatory effect of Curcuma longa rhizome extract as an adjuvant therapy for reversal reaction patients by analyzing serum levels of IL-6 as a marker of inflammation. The pre and post-test randomized single-blinded controlled trial was conducted on two groups, namely control (RR patients with steroid therapy & placebo) and treatment (steroid therapy & Curcuma longa rhizome extract 1 gram/day). IL-6 serum levels were analyzed from sampling before and after the intervention for one month. The serum levels of IL-6 post-test in the control group were significantly higher than those of the pre-test. The treatment group showed lower serum levels of IL-6 post-test compared to pre-test, although there was no significant difference. Curcuma longa rhizome extract 1 gram/day for one month as adjuvant therapy for patients with type 1 leprosy reaction did not significantly reduce serum IL-6 levels