Jurnal Health Sains (JHS)
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    SKIN CANCER IN CHILDREN WITH XERODERMA PIGMENTOSUM

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    Introduction: Xeroderma pigmentosum) is a rare disease, inherited in an autosomal recessive manner with disturbances in the repair of deoxyribonucleic acid (DNA) which often occur in malignancy. Irreversible DNA lesions and mutations also occur in the genes which regulate skin cancer development in Xeroderma Pigmentosum. Purpose: To explain the signs, symptoms, and management of  skin cancer Xeroderma Pigmentosum. Case Report : A 6 year old girl with basal cell carcinoma arising from Xeroderma pigmentosum.  The histopathological picture of the left nasolabial biopsy preparation was found to show basal cell carcinoma (BCC). The patient was treated with 5FU administration and were followed after 6 week In the second patient, a 3 year old boy, squamous cell carcinoma in the oocipital area. From the histopathological picture, moderately differentiated squamous cell carcinoma on the left frontalis occipital dextra and corresponds to mottled hypermegrance on the parietal dextra. In this patient, a wide excision of the occipital lump was performed and the defect was closed with a full-thickness skin graft. Provided education to the parents of both patients for direct prevention of sun exposure by using sunscreen/hats. Discussion and Conclusion: Xeroderma Pigmentosum patients who are Xeroderma Pigmentosum  to ultraviolet radiation (UV) can result in the development of highly cancerous lesions consisting of squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and malignant melanoma (MM). Clinical management of Xeroderma Pigmentosum includes sun avoidance, minimizing UV eXeroderma Pigmentosumosure, early detection, skin lesions, and genetic counseling. Topical application of 5-fluorouracil or imiquimod is used for premalignant lesions, and surgical excision is performed for malignant neoplasms of the skin, tongue, eyelids, conjunctiva, and cornea

    The Influence Of Price, Product Quality And Promotion On The Purchase Decision Of Villa Banana Cake Products At The Botania Outlet Batam City

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    In an era where technology is so sophisticated as it is today, it triggers very tight competition in the business world, plus the Covid-19 pandemic outbreak that originated in Wuhan, China in early 2020 until today has forced business actors to work even harder. All means and efforts are made so that their business can survive or even increase and can face increasingly fierce competition. The results of this study indicate that price, product quality and promotion have a simultaneous effect on purchasing decisions. Price, product quality and promotion together will have an influence on purchasing decision

    ANALYSIS OF HR TURNOVER AT RSIA RESTU BUNDA, BANDAR LAMPUNG

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    The importance of HR in an organization because it has an important role in helping the organization in achieving its goals. RSIA Restu Bunda, Bandar Lampung which aims to accelerate the achievement of saving the death of pregnant women and their babies to the delivery process requires human resources in it. However, the problem that often occurs is the change of human resources, including in this hospital. This study aims to analyze the turnover of human resources at RSIA Restu Bunda in Bandar Lampung. This research uses a descriptive method with a qualitative approach. Collection techniques with documentation and interview techniques, while data analysis is inductive / qualitative and qualitative research results emphasize meaning rather than generalization by triangulation (combined). The results showed that there are five factors driving HR turnover are dissatisfaction with public facilities, social institutions and welfare in terms of income and ease of access to obtain basic daily needs and relationships with superiors. Thus, the importance of HR management strategies so that there is no change in invention. Some of the roles of HR management in managing HR turnover are the role of the recruitment system, training, compensation and benefits, career development and promotion, rewards and performance appraisals

    Control Of Various Types Of Traps Flies In Pasar Aur Duri Jambi City

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    The background of flies as a mechanical vector of flies can spread disease, through germs (seeds of disease) attached to the legs, feathers, wings, body of flies so that flies can be dangerous to humans. The purpose of this study was to determine the control of various types of fly traps in Pasar Aur Duri Jambi City. This research method is quasi-experimental with a post test only design with control group with a statistical test approach Anova.The location of the study was on the stalls of fish traders, vegetable traders, and chicken traders in Pasar Aur Duri Jambi City. There are three types of traps, namely fly trap blowers, fly traps, and glue traps. Repetition in the study 9 times. The results of the study The number of flies trapped with fly trap blowers as fly control in Lapak 1 (fish traders), Lapak 2 (chicken meat traders) and stall 3 (vegetable traders) Pasar Aur Duri Jambi City showed that in the 1st to 9th repeats, the average number of flies trapped to the fly trap blower was 6 flies with flies trapped in Chrysomia megachepala as many as 116 flies. While the number of flies in the fly trap trapped was 54 flies, the average fly was 2 flies, and for the fly glue trap showed as many as 121 flies with an average of 3 flies, the type of fly trapped was Chrysomia megachepala. The results of one way Anova analysis showed that there was a significant difference in the number of flies trapped between Fly trap blowers, Fly traps, and Glue flies with F = 71.86; p < 0.001. Post-hoc analysis with the LSD method also showed that the Fly trap blower (M = 6.00; SD = 0.866) had significantly more flies than fly traps (M = 2.00; SD = 0.50) and Glue flies (M = 4.44; SD = 0.73), p < 0.001. While glue flies have a significantly greater number of flies trapped than fly traps (p < 0.001).  Conclusion: The highest number of flies with a total of 334 flies with the effectiveness of trapping tools is Fly trap blowers and the most common type of fly Chrysomia megacephala. Suggestions for fly control in Pasar Aur Duri Jambi City should be to increase the full power of the portable flytrap blower that is easy to carry and place anywher

    Pengaruh Kualitas Pelayanan terhadap Loyalitas Pasien yang Dimediasi Oleh Pemasaran Relasional dan Kepuasan Pasien

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    Progress in the economic field, indirectly has an impact on the rapid development in the field of health, especially hospitals. The best service is currently the main focus for each hospital to increase the competitiveness and selling power of the hospital. The study aims to analyze the effect of quality of service on patient loyalty at Kartika Pulomas Hospital East Jakarta, with patient satisfaction and relational marketing as intervening variables. The study was conducted by collecting quantitative data through the dissemination of questionnaires to 255 respondents. The analytical technique used is Structural Equation Modelling (SEM) with lisrel. The results showed that quality of service had a significant effect on patient loyalty with patient satisfaction and relational marketing as intervening variables; Quality of service has a significant effect on relational satisfaction and marketing, but has no effect on patient loyalty; Patient satisfaction and relational marketing have a significant effect on patient loyalty. Managerial implications based on the results of the study is that it is recommended that hospitals make information containers both printed and digital; evaluate the running of SPO (Standard Operating Procedure); Complete supporting inspection facilities; Improve employee abilities and skills through seminars or trainingKemajuan di bidang perekonomian, secara tidak langsung memberikan dampak pada perkembangan yang cukup pesat di bidang kesehatan, khususnya rumah sakit. Pelayanan terbaik saat ini menjadi fokus utama bagi setiap rumah sakit guna meningkatkan daya saing dan daya jual rumah sakit tersebut. Penelitian ini bertujuan untuk menganalisis pengaruh kualitas pelayanan terhadap loyalitas pasien di Rumah Sakit Kartika Pulomas Jakarta Timur, dengan kepuasan pasien dan pemasaran relasional sebagai variabel intervening. Penelitian dilakukan dengan mengumpulkan data kuantitatif melalui penyebaran kuesioner kepada 255 responden. Teknik analisis yang digunakan adalah Structural Equation Modelling (SEM) dengan lisrel. Hasil penelitian menunjukkan bahwa Kualitas pelayanan berpengaruh signifikan terhadap loyalitas pasien dengan kepuasan pasien dan pemasaran relasional sebagai variabel intervening; Kualitas pelayanan berpengaruh signifikan terhadap kepuasan dan pemasaran relasional, namun tidak berpengaruh terhadap loyalitas pasien; Kepuasan pasien dan pemasaran relasional berpengaruh signifikan terhadap loyalitas pasien. Implikasi managerial berdasarkan hasil penelitian adalah Disarankan agar rumah sakit membuat wadah informasi baik cetak maupun digital; mengevaluasi berjalannya SPO (Standar Prosedur Operasional); Melengkapi fasilitas pemeriksaan penunjang; Meningkatkan kemampuan dan keterampilan karyawan melalui seminar atau pelatiha

    Implementasi Dana Alokasi Khusus (DAK) Non Fisik Kefarmasian di Kabupaten Purwakarta Tahun 2019

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    Non-physical DAK for pharmaceuticals is one of the APBN budgets given to districts/cities in the pharmaceutical sector with a menu of distribution of drugs, vaccines and medical consumables (BMHP) as well as support for the use of information systems or drug logistics applications and electronic BMHP as a government effort to guarantee availability of drugs in primary health services. The focus of this research is the implementation of non-physical DAK pharmaceutical BOK implementation policies at the Purwakarta District Health Office. The performance of policy implementation needs to be analyzed in order to evaluate to generate feedback for the next policy development process. Data collection techniques are through in-depth interviews with key informants, observation, and document review. This research uses the Van Meter and Van Horn policy implementation model approach. The results of the research show that it is still necessary to improve the understanding of implementers in planning activities and the low compliance of reporting on the realization of Non-physical DAK in accordance with the established technical guidelinesDana Alokasi Khusus (DAK) Non Fisik Kefarmasian merupakan salah satu anggaran APBN yang diberikan kepada Kabupaten/Kota di bidang Kefarmasian dengan menu distribusi obat, vaksin, dan bahan medis habis pakai (BMHP) serta dukungan pemanfaatan sistem informasi atau aplikasi logistik obat dan BMHP secara elektronik sebagai upaya pemerintah dalam menjamin ketersediaan obat di pelayanan kesehatan dasar. Fokus dalam penelitian ini adalah implementasi kebijakan penerapan DAK non fisik BOK kefarmasian di Dinas Kesehatan Kabupaten Purwakarta. Kinerja implementasi kebijakan perlu dianalisis dalam rangka evaluasi untuk menghasilkan umpan balik bagi proses pengembangan kebijakan selanjutnya. Teknik pengumpulan data yaitu melalui wawancara mendalam kepada informan kunci, observasi, dan telaah dokumen. Penelitian ini menggunakan pendekatan model implementasi kebijakan Van Meter dan Van Horn. Hasil penelitian diperoleh bahwa masih perlu ditingkatkan pemahaman terhadap pelaksana dalam menyusun perencanaan kegiatan serta rendahnya kepatuhan pelaporan realisasi DAK Non fisik sesuai dengan Petunjuk teknis yang ditetapka

    Model Perencanaan dan Pengadaan Obat dengan Metode ABC Indeks Kritis (Studi Kasus Di Rumah Sakit Jiwa dr. Soeharto Heerdjan Jakarta)

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    The drug planning and procurement system is a determining factor for drug availability and budget requirements. A good method can be applied to create a good drug planning and procurement system, one of which is the ABC Critical Index method. With this method, priority drugs can be grouped that have a large investment value. RSJ dr. Suharto Heerdjan has never done an ABC Critical Index analysis and the problem that often occurs is the stock of drugs is empty. Suharto Heerdjan Jakarta. This type of research is descriptive qualitative, using data on drug use for the period January 2020 to June 2021 and filling out the VEN questionnaire by 15 doctors. The analysis was carried out using the ABC Critical Index method. The results of the analysis showed that of the 351 types of drugs that were included in group A, there were 6 types of critical index (2%), group B had 119 types of critical index (33.6%) and group C had a critical index of 119 types (33.6%). 226 species (64.4%). Drugs included in group A of the critical index are psychotropic drugs, namely Clozapine 100 mg, Clozapine 25 mg, Trihexyphenidil 2 mg, Risperidone 2 mg, Depakote 500 mg ER, Abilify 10 mg Discmelt. Group A critical index drugs are a priority to be planned and procured, so for the six types of drugs, the estimated demand for 2022, EOQ, SS and ROP are calculated with the following results: Clozapine 100 mg needs 194,844 tablets, EOQ 5,401 tablets, SS 16,953 tablets, ROP 17,654 tablets; Clozapine 25 mg needs 407,080 tablets, EOQ 21,338 tablets, SS 25,892 tablets, ROP 27,194 tablets; Trihexyphenidil 2 mg needs 1,695,404 tablets, EOQ 93,399 tablets, SS 29,544 tablets, ROP 33,387 tablets; Risperidone 2 mg needs 1,073,301 tablets, EOQ 42,897 tablets, SS 12,963 tablets, ROP 14,967 tablets; Depakote 500 mg ER needs 107,971 tablets, EOQ 3,068 tablets, SS 1,980 tablets, ROP 2,110 tablets; Abilify 10 mg discmelt needs 99,737 tablets, EOQ 1,426 tablets, SS 587 tablets, ROP 680 tablets. The application of the drug planning and procurement model using the ABC Critical Index method in research can help determine drug priorities, adjust to budget availability without disrupting the smooth running of services, and improve drug use efficiencySistem perencanaan dan pengadaan obat merupakan faktor penentu ketersediaan obat dan kebutuhan anggaran. Metode yang baik dapat diterapkan untuk menciptakan sistem perencanaan dan pengadaan obat yang baik, salah satunya dengan metode ABC Indeks Kritis. Dengan metode ini maka dapat dikelompokkan obat prioritas yang memiliki nilai investasi besar. RSJ dr. Soeharto Heerdjan belum pernah melakukan analisis ABC Indeks Kritis dan masalah yang sering terjadi adalah stok obat kosong. Tujuan penelitian ini adalah menganalisis sistem perencanaan dan pengadaan obat di RSJ dr. Soeharto Heerdjan Jakarta. Jenis penelitian ini yaitu deskriptif kualitatif, menggunakan data pemakaian obat periode Januari 2020 sampai dengan Juni 2021 dan pengisian kuesioner VEN oleh 15 orang dokter. Analisis dilakukan dengan metode ABC Indeks Kritis. Hasil analisis menunjukkan bahwa dari 351 jenis obat yang termasuk dalam kelompok A indeks kritis ada 6 jenis (2%), kelompok B indeks kritis ada 119 jenis (33,6%) dan kelompok C indeks kritis ada 226 jenis (64,4%). Obat yang masuk dalam kelompok A indeks kritis adalah obat-obatan psikotropika, yaitu Clozapine 100 mg, Clozapine 25 mg, Trihexyphenidil 2 mg, Risperidone 2 mg, Depakote 500 mg ER, Abilify 10 mg Discmelt. Obat kelompok A indeks kritis menjadi prioritas untuk direncanakan dan diadakan, sehingga pada keenam jenis obat tersebut dilakukan perhitungan perkiraan kebutuhan tahun 2022, EOQ, SS dan ROP dengan hasil sebagai berikut: Clozapine 100 mg kebutuhan 194.844 tablet, EOQ 5.401 tablet, SS 16.953 tablet, ROP 17.654 tablet; Clozapine 25 mg kebutuhan 407.080 tablet, EOQ 21.338 tablet, SS 25.892 tablet, ROP 27.194 tablet; Trihexyphenidil 2 mg kebutuhan 1.695.404 tablet, EOQ 93.399 tablet, SS 29.544 tablet, ROP 33.387 tablet; Risperidone 2 mg kebutuhan 1.073.301 tablet, EOQ 42.897 tablet, SS 12.963 tablet, ROP 14.967 tablet; Depakote 500 mg ER kebutuhan 107.971 tablet, EOQ 3.068 tablet, SS 1.980 tablet, ROP 2.110 tablet; Abilify 10 mg discmelt kebutuhan 99.737 tablet, EOQ 1.426 tablet, SS 587 tablet, ROP 680 tablet. Penerapan model perencanaan dan pengadaan obat dengan metode ABC Indeks Kritis dalam penelitian dapat membantu menentukan prioritas obat, menyesuaikan dengan ketersediaan anggaran tanpa  mengganggu kelancaran pelayanan, dan meningkatkan efisiensi pemakaian obat

    PENGARUH VARIASI KADAR ASAM BASA TERHADAP WAKTU LARUT GRANUL EFFERVESCENT EKSTRAK HERBA MENIRAN (Phyllanthus niruri L.)

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    One of the plants that have the potential to be developed as traditional medicine is the green meniran herb (Phyllanthus niruri L.). The results showed that meniran herbs contain lignin and terpenoid compounds that have potential as antibacterials. People use meniran as a medicine for itching by drinking boiled water of meniran, lowering glucose and diuretic levels, and increasing body resistance. Meniran herbs were extracted by the maceration method with 96% ethanol as solvent. Then refluxed for 6 hours with the same solvent. Meniran herb extract was formulated into effervescent granules with varying levels of acid sources, namely citric acid, and tartaric acid, with a ratio of FI (0.5 g: 1.5 g), FII (1 g: 1 g), FIII (1.5 g: 0.5 g). Effervescent granules were evaluated physically including flow rate, angle of repose, drying shrinkage, and dissolving time. The results of the study showed that the extract of the meniran herb contained flavonoids, alkaloids, sterols and triterpenoids, saponins, polyphenols, and tannins. The flow rate of each formula increased with the addition of tartaric acid in the formula, the higher the tartaric acid added, the faster the flow time. The results of the dissolution time showed that the greater the concentration of sodium bicarbonate, the longer the dissolution time of the effervescent granule preparation. Based on the results obtained, all formulas have a pH value of 4-5.   Salah satu tanaman yang memiliki potensi untuk dikembangkan sebagai obat tradisional adalah herba meniran hijau (Phyllanthus niruri L.). Hasil penelitian menunjukkan bahwa herba meniran mengandung senyawa lignin dan terpenoid yang mempunyai potensi sebagai antibakteri. Masyarakat menggunakan meniran sebagai obat gatal-gatal dengan cara meminum air rebusan meniran, menurunkan kadar glukosa dan diuretik serta meningkatkan daya tahan tubuh. Herba meniran dibuat ekstrak dengan metode maserasi dengan pelarut etanol 96%. Selanjutnya direfluk selama 6 jam dengan pelarut yang sama. Esktrak herba meniran diformulasikan menjadi granul effervescent dengan variasi kadar sumber asam yaitu asam sitrat dan asam tartrat, dengan perbandingan FI (0,5g : 1,5g), FII (1g : 1g), FIII (1,5g : 0,5g). Granul effervescent dilakukan evaluasi fisik meliputi laju alir, sudut diam, susut pengeringan, waktu larut. Hasil dari penelitian didapatkan bahwa ekstrak herba meniran mengandung flavonoid, alkaloid, sterol dan triterpenoid, saponin, polifenol dan tannin. Kecepatan alir masing-masing formula meningkat seiring bertambahnya asam tartrat yang ditambahkan dalam formula, semakin tinggi asam tartrat yang ditambahkan maka waktu alirnya semakin cepat. Hasil waktu larut menunjukkan bahwa semakin besar konsentrasi natrium bikarbonat maka semakin lama waktu larut dari sediaan granul effervescent. Berdasarkan hasil yang diperoleh, semua formula memiliki nilai pH 4-5

    Influence Of Workload And Job Satisfaction Of Pharmaceutical Workers On The Achievement Of Quality Indicators With Motivation As Intervening Variables In Jakarta Dharmais Cancer Hospital

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    Based on an initial survey of  10 pharmacists, there are still many employees (10%) who complain of being tired when the office, especially the morning service, sometimes doesn't have time to rest, eat, plus pharmacists who don't come because of illness, causing the workload to be more The survey results also showed 50% of employees expressed job dissatisfaction this was related to salary provision, relationships with superiors and job placements were not in accordance with their skills and abilities. In addition, 20% of employees show low work motivation, this is because the work environment is not conducive and the workload is high. In addition to the results of observations based on the RSKD suggestion box, the phenomenon of complaints felt by 3 patients / families, including "long pharmacy service, employees do not smile and behave rudely". Long waiting time is one of the components that have the potential to cause patient dissatisfaction. Objective: To analyze the effect of workload and job satisfaction on the achievement of quality indicators with motivation as an intervening variable for pharmacists at Dharmais Cancer Hospital. The research design that will be used in this research is a quantitative approach research model. Quantitative model is a decision model that uses numbers. In addition, based on numerical or numerical data and decision models produce decision variables in the form of numbers with a cross sectional approach. There is a  significant effect between workload on the motivation of pharmacists at Dharmais Cancer Hospital, There is a significant influence between job satisfaction on the motivation of pharmacists at Dharmais Cancer Hospital, There is a significant influence between workload on the achievement of quality indicators in the Home Pharmacy Installation Dharmais Cancer. , There is a significant effect between job satisfaction on the achievement of quality indicators in the Pharmacy Installation of Dharmais Cancer Hospital., There is a significant influence between workload and job satisfaction on the achievement of quality indicators with motivation as an influential factor in the Pharmacy Installation of Dharmais Cancer Hospita

    Analysis Of Nurse Workload On Implementation Of Patient Safety And Teamwork With Caring Behavior As Mediation Variables At Metro Hospitals Cikupa

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    The central issue of nursing is currently developing in the era of globalization and the era of hospital competition is the application of patient safety goals in hospitals. Most of the components of implementing the six patient safety goals are in the hands of nurses. Maintaining patient safety during treatment cannot be separated from the workload and caring attitude of a nurse who takes care of patients. Therefore, the authors want to examine the extent to which the workload and caring attitude of nurses and teamwork affect the application of patient safety. The main purpose of this study was to analyze the relationship between nurses' workload and teamwork on the application of patient safety goals and caring behavior as an intervening variable. The research population was inpatient and outpatient nurses with a sample number is 60 nurses. The research design uses quantitative data with a causative approach, with a focus on cause-and-effect relationships. Statistical methods for data analysis used in this study were univariate statistics, three-box methods, and path analysis to analyze the pattern of relationships between variables. The results showed: 1). Workload had a simultaneous effect on the variables of teamwork, caring behavior, and goals. patient safety in the hospital  2). Nurse workload has a positive effect on the variable implementation of patient safety goals. 3). The nurse's workload has a positive effect on the variable of the implementation of caring behavior. 4). Caring behavior has a positive effect on the variable of applying patient safety goals. 5). Nurse's workload has a positive effect on the teamwork variable 6). The teamwork variable did not significantly affect the variable implementation of patient safety goals.Conclusion: nurses' workload variables have a significant effect on teamwork, caring behavior, and patient safety goals. Caring behavior has a positive effect on patient safety goals, but teamwork does not significantly affect the implementation of patient safety goals.  Isu sentral keperawatan yang saat ini berkembang di era globalisasi dan era persaingan rumah sakit, adalah penerapan tujuan keselamatan pasien di rumah sakit. Sebagian besar komponen penerapan enam tujuan keselamatan pasien berada di tangan perawat. Menjaga keselamatan pasien selama perawatan tidak lepas dari beban kerja dan sikap kepedulian seorang perawat yang merawat pasien. Oleh karena itu, penulis ingin mengkaji sejauh mana beban kerja dan sikap caring perawat serta teamwork mempengaruhi penerapan patient safety. Tujuan utama dari penelitian ini adalah untuk menganalisis hubungan antara beban kerja perawat dan kerja tim terhadap penerapan tujuan keselamatan pasien dan perilaku caring sebagai variabel intervening. Populasi penelitian adalah perawat rawat inap dan rawat jalan dengan jumlah sampel 60 perawat. Desain penelitian menggunakan data kuantitatif dengan pendekatan kausatif, dengan fokus pada hubungan sebab akibat. Metode statistik analisis data yang digunakan dalam penelitian ini adalah statistik univariat, metode three box dan analisis jalur untuk menganalisis pola hubungan antar variabel. Hasil penelitian menunjukkan: 1). Beban kerja berpengaruh secara simultan terhadap variabel kerjasama tim, perilaku peduli dan tujuan. keselamatan pasien di rumah sakit 2). Beban kerja perawat, berpengaruh positif terhadap variabel implementasi tujuan keselamatan pasien. 3). Beban kerja perawat berpengaruh positif terhadap variabel implementasi perilaku caring. 4). Perilaku Caring berpengaruh positif terhadap variabel penerapan tujuan keselamatan pasien. 5). Beban kerja perawat berpengaruh positif terhadap variabel teamwork 6). Variabel kerjasama tim tidak berpengaruh signifikan terhadap variabel implementasi tujuan keselamatan pasien

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